Research Topics
Genomes and Genes | Tsutomu KishiSummaryAffiliation: RIKEN Brain Science Institute Country: Japan Publications
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Detail Information
Publications
Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclinHiroaki Seino
Division of Mutagenesis, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
Mol Cell Biol 23:3497-505. 2003....
The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurinTsutomu Kishi
Kishi Initiative Research Unit, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
Proc Natl Acad Sci U S A 104:17418-23. 2007..The results provide insight into the mechanism involved in maintaining proper responses to Ca(2+) signals...
A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entryTsutomu Kishi
Kishi Initiative Research Unit, RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
Proc Natl Acad Sci U S A 105:14497-502. 2008..These findings indicate that the SCF(Cdc4) complex regulates S phase entry not only through degradation of Sic1, but also through degradation of Swi5...
Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligaseSachie Asada
Kishi Initiative Research Unit, Frontier Research System, 2 1 Hirosawa, Wako, Saitama, Japan
Int J Mol Med 22:95-104. 2008..These results suggest that H2O2 induces SCF beta-TrCP-mediated ubiquitination of RCAN1, leading to a decrease in the protein level of RCAN1...
Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1Sachie Asada
Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1 1 1 Tennoudai, Tsukuba, Ibaraki 305 8577, Japan
Cell Signal 19:519-27. 2007..These results suggest that Foxo1 is specifically phosphorylated by Erk and p38, and that this phosphorylation regulates the function of Foxo1 as a coactivator for Ets-1...
