Affiliation: RIKEN Brain Science Institute
- Motor recovery and microstructural change in rubro-spinal tract in subcortical strokeYohei Takenobu
Division of Neurology, Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, Osaka, Japan Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
Neuroimage Clin 4:201-8. 2014....
- Neuroimaging for optimization of stem cell therapy in Parkinson's diseaseTakuya Hayashi
Functional Architecture Imaging Unit, RIKEN Center for Life Science Technologies, 6 7 3 Minatojima minami machi, Chuo Ku, Kobe, Hyogo 650 0047, Japan
Expert Opin Biol Ther 13:1631-8. 2013..Neuroimaging techniques allow us to measure various biological markers repeatedly and quantitatively, which may serve as a powerful tool for optimizing the use of stem cells in preclinical and clinical trials. ..
- Kinetics of neurodegeneration based on a risk-related biomarker in animal model of glaucomaTakuya Hayashi
Functional Probe Research Laboratory, RIKEN Center for Molecular Imaging Science, Kobe, Hyogo, 650 0047, Japan
Mol Neurodegener 8:4. 2013..Here, we show predictability of a model with risk-based kinetics of neurodegeneration, whereby neurodegeneration proceeds as probabilistic events depending on the risk...
- Autologous mesenchymal stem cell-derived dopaminergic neurons function in parkinsonian macaquesTakuya Hayashi
Functional Probe Research Laboratory, Center for Molecular Imaging Science, RIKEN, Kobe, Japan
J Clin Invest 123:272-84. 2013..These data suggest that transplantation of differentiated autologous MSCs may represent a safe and effective cell therapy for Parkinson's disease...
- Dorsolateral prefrontal and orbitofrontal cortex interactions during self-control of cigarette cravingTakuya Hayashi
McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, QC, Canada H3A 2B4
Proc Natl Acad Sci U S A 110:4422-7. 2013..These findings indicate that DLPFC builds up value signals based on knowledge of drug availability, and support a model wherein aberrant circuitry linking dorsolateral prefrontal and orbitofrontal cortices may underlie addiction...
- Quantification of regional cerebral blood flow in rats using an arteriovenous shunt and micro-PETTakayuki Ose
Functional Probe Research Laboratory, RIKEN Center for Molecular Imaging Science, Chuo Ku, Kobe 650 0047, Japan
Nucl Med Biol 39:730-41. 2012..We therefore tested the feasibility of using an arteriovenous (AV) shunt in rats for less invasive blood analysis...
- Establishment of in vivo brain imaging method in conscious miceHiroshi Mizuma
Functional Probe Research Laboratory, RIKEN Center for Molecular Imaging Science, Chuo Ku, Kobe, Japan
J Nucl Med 51:1068-75. 2010..Here, we established an in vivo imaging system for conscious mice to reveal the physiologic regional cerebral glucose metabolic rate (rCMRglu) with (18)F-FDG PET...
- Linkage between the midline cortical serotonergic system and social behavior traits: positron emission tomography studies of common marmosetsChihiro Yokoyama
Functional Probe Research Laboratory, RIKEN Center for Molecular Imaging Science, Kobe, Hyogo 650 0047, Japan
Cereb Cortex 23:2136-45. 2013..These results suggest that the midline cortical serotonergic system is crucial in social behavior traits and its subregions are functionally segregated in socio-emotional processing. ..
- Temporal plasticity involved in recovery from manual dexterity deficit after motor cortex lesion in macaque monkeysYumi Murata
Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki 3058568, Japan, Research Fellow of the Japan Society for the Promotion of Science, Chiyoda ku, Tokyo, 1020083, Japan
J Neurosci 35:84-95. 2015....
- An acute psychosocial stress enhances the neural response to smoking cuesAlain Dagher
Montreal Neurological Institute, McGill University, 3801 University St, Montreal QC, Canada H3A 2B4
Brain Res 1293:40-8. 2009..Stress-induced limbic deactivation predicted subsequent neural cue-reactivity. We suggest that stress increases the incentive salience of drug cues...