RIKEN Brain Science Institute

Summary

Organization: RIKEN Brain Science Institute
Country: Japan

Top Publications

  1. doi An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio
    Yutaka Kodama
    Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA
    Biotechniques 49:793-805. 2010
  2. doi Assessment of chromosomal integrity using a novel live-cell imaging technique in mouse embryos produced by intracytoplasmic sperm injection
    Kazuo Yamagata
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN Kobe, Minatojima minamimachi 2 2 3, Chuo Ku, Kobe City, Hyogo 651 0047, Japan
    Hum Reprod 24:2490-9. 2009
  3. ncbi Next-generation gene targeting in the mouse for functional genomics
    Yoichi Gondo
    Mutagenesis and Genomics Team, RIKEN BioResource Center, 3 1 1 Koyadai, Tsukuba, Ibaraki 305 0074, Japan
    BMB Rep 42:315-23. 2009
  4. doi Age-related spatial and nonspatial short-term memory in Cav2.1alpha1 mutant mice, Rolling Nagoya
    Eiki Takahashi
    RIKEN Brain Science Institute, Research Resources Center, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    Behav Brain Res 204:241-5. 2009
  5. doi Short communication: Establishment of a new polymerase chain reaction-sequence-based typing method for genotyping cattle major histocompatibility complex class II DRB3
    S N Takeshima
    Viral Infectious Diseases Unit, RIKEN, Wako, Saitama 351 0198, Japan
    J Dairy Sci 92:2965-70. 2009
  6. doi Genetic analysis of glucosidase II beta-subunit in trimming of high-mannose-type glycans
    Taisuke Watanabe
    RIKEN Advanced Science Institute, Wako, Saitama, Japan
    Glycobiology 19:834-40. 2009
  7. doi Prevotella falsenii sp. nov., a Prevotella intermedia-like organism isolated from monkey dental plaque
    Mitsuo Sakamoto
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama 351 0198, Japan
    Int J Syst Evol Microbiol 59:319-22. 2009
  8. doi Taste reactivity and its modulation by morphine and methamphetamine in C57BL/6 and DBA/2 mice
    Barbara Cagniard
    Molecular Neuropathology Group, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama, 351 0198, Japan
    Physiol Behav 96:412-20. 2009
  9. doi Ca2+ induces macropinocytosis via F-actin depolymerization during growth cone collapse
    Hiroyuki Kabayama
    Laboratory for Developmental Neurobiology, Brain Science Institute, The Institute of Physical and Chemical Research RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Mol Cell Neurosci 40:27-38. 2009
  10. doi Generation of mice derived from embryonic stem cells using blastocysts of different developmental ages
    Hiroshi Ohta
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Chuo Ku, Kobe 650 0047, Japan
    Reproduction 136:581-7. 2008

Detail Information

Publications62

  1. doi An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio
    Yutaka Kodama
    Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA
    Biotechniques 49:793-805. 2010
    ..This mutation allows a 4-fold increase in the S/N ratio of the BiFC assay in living cells. This improved Venus-based BiFC system will facilitate PPI studies in various biological research fields...
  2. doi Assessment of chromosomal integrity using a novel live-cell imaging technique in mouse embryos produced by intracytoplasmic sperm injection
    Kazuo Yamagata
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN Kobe, Minatojima minamimachi 2 2 3, Chuo Ku, Kobe City, Hyogo 651 0047, Japan
    Hum Reprod 24:2490-9. 2009
    ..One major cause is thought to be embryonic chromosomal abnormalities. However, there is no direct evidence of how these occur or how they affect pregnancy outcomes...
  3. ncbi Next-generation gene targeting in the mouse for functional genomics
    Yoichi Gondo
    Mutagenesis and Genomics Team, RIKEN BioResource Center, 3 1 1 Koyadai, Tsukuba, Ibaraki 305 0074, Japan
    BMB Rep 42:315-23. 2009
    ....
  4. doi Age-related spatial and nonspatial short-term memory in Cav2.1alpha1 mutant mice, Rolling Nagoya
    Eiki Takahashi
    RIKEN Brain Science Institute, Research Resources Center, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    Behav Brain Res 204:241-5. 2009
    ..In perirhinal cortex, there were no significantly different expressions. Alteration of age-dependent expressions of Cav2.1 channels differs in different regions with related effects on behavioral performances...
  5. doi Short communication: Establishment of a new polymerase chain reaction-sequence-based typing method for genotyping cattle major histocompatibility complex class II DRB3
    S N Takeshima
    Viral Infectious Diseases Unit, RIKEN, Wako, Saitama 351 0198, Japan
    J Dairy Sci 92:2965-70. 2009
    ..This new method will contribute to high-throughput genotyping of BoLA-DRB3 by sequence-based typing...
  6. doi Genetic analysis of glucosidase II beta-subunit in trimming of high-mannose-type glycans
    Taisuke Watanabe
    RIKEN Advanced Science Institute, Wako, Saitama, Japan
    Glycobiology 19:834-40. 2009
    ..These results suggested that the beta-subunit confers the substrate specificity toward di- and monoglucosylated glycans on the glucose-trimming activity of the alpha-subunit...
  7. doi Prevotella falsenii sp. nov., a Prevotella intermedia-like organism isolated from monkey dental plaque
    Mitsuo Sakamoto
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama 351 0198, Japan
    Int J Syst Evol Microbiol 59:319-22. 2009
    ..nov. is proposed. The type strain is 04052(T) (=JCM 15124(T) =CCUG 56137(T))...
  8. doi Taste reactivity and its modulation by morphine and methamphetamine in C57BL/6 and DBA/2 mice
    Barbara Cagniard
    Molecular Neuropathology Group, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama, 351 0198, Japan
    Physiol Behav 96:412-20. 2009
    ....
  9. doi Ca2+ induces macropinocytosis via F-actin depolymerization during growth cone collapse
    Hiroyuki Kabayama
    Laboratory for Developmental Neurobiology, Brain Science Institute, The Institute of Physical and Chemical Research RIKEN, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Mol Cell Neurosci 40:27-38. 2009
    ..We propose that the coordinated regulation of actin cytoskeletal reorganization and macropinocytosis-mediated retrograde membrane trafficking may contribute to Ca(2+)-induced axon growth inhibition...
  10. doi Generation of mice derived from embryonic stem cells using blastocysts of different developmental ages
    Hiroshi Ohta
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Chuo Ku, Kobe 650 0047, Japan
    Reproduction 136:581-7. 2008
    ..We also discuss a comparison of the present findings with those of our previous study, where ES mice were generated using an aggregation method employing the same ES cell lines...
  11. doi Microbacterium hatanonis sp. nov., isolated as a contaminant of hairspray
    Mohammad Abdul Bakir
    Microbe Division Japan Collection of Microorganisms, RIKEN BioResource Center, Wako, Saitama 351 0198, Japan
    Int J Syst Evol Microbiol 58:654-8. 2008
    ..nov. is proposed. The type strain is FCC-01(T) (=JCM 14558(T) =DSM 19179(T))...
  12. ncbi Multilayer nonnegative matrix factorization using projected gradient approaches
    Andrzej Cichocki
    Laboratory for Advanced Brain Signal Processing, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    Int J Neural Syst 17:431-46. 2007
    ..Our new implementations of NMF are demonstrated with the simulations performed for Blind Source Separation (BSS) data...
  13. ncbi An artificial aptazyme-based riboswitch and its cascading system in E. coli
    Atsushi Ogawa
    Bioengineering Laboratory, RIKEN The Institute of Physical and Chemical Research, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Chembiochem 9:206-9. 2008
  14. ncbi Molecular characterization of microbial mutations induced by ion beam irradiation
    Hiroyuki Ichida
    Graduate School of Science and Technology, Chiba University, Matsudo, Chiba 271 8510, Japan
    Mutat Res 639:101-7. 2008
    ..We found also that ion beams, particularly "heavier" ion beams, can produce single gene disruptions and may present an effective alternative to transgenic approaches...
  15. doi Biomimetic approach to tacit learning based on compound control
    Shingo Shimoda
    RIKEN Brain Science Institute BSI Toyota Collaboration Center, Nagoya 463 0003, Japan
    IEEE Trans Syst Man Cybern B Cybern 40:77-90. 2010
    ..We show that the individual activities can generate optimized behaviors from a particular global viewpoint, i.e., autonomous rhythm generation and learning of balanced postures, without using global performance indices...
  16. pmc Kernel bandwidth optimization in spike rate estimation
    Hideaki Shimazaki
    RIKEN Brain Science Institute, Saitama, Japan
    J Comput Neurosci 29:171-82. 2010
    ....
  17. doi Physiological function and molecular basis of STIM1-mediated calcium entry in immune cells
    Yoshihiro Baba
    Laboratory for Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan
    Immunol Rev 231:174-88. 2009
    ....
  18. ncbi [Recognition of dynamic facial expressions in peripheral and central vision]
    Tomomi Fujimura
    JST ERATO Okanoya Emotional Information Project, RIKEN, Hirosawa, Wako 351 0198, Japan
    Shinrigaku Kenkyu 81:348-55. 2010
    ..These findings suggest that an effect of dynamic information is more salient in peripheral vision than in central vision for recognizing certain facial expressions...
  19. doi A global single-cell cDNA amplification method for quantitative microarray analysis
    Kazuki Kurimoto
    Laboratory for Mammalian Germ Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan
    Methods Mol Biol 687:91-111. 2011
    ..The promoter-tagged cDNA is purified with gel electrophoresis and amplified with one final cycle of PCR...
  20. doi Vapochromic and mechanochromic tetrahedral gold(I) complexes based on the 1,2-bis(diphenylphosphino)benzene ligand
    Masahisa Osawa
    Luminescent Materials Laboratory, RIKEN The Institute of Physical and Chemical Research, Hirosawa 2 1, Wako Shi, 351 0198 Japan
    Chemistry 16:12114-26. 2010
    ..We have demonstrated that the symmetry reductions are responsible for the phosphorescence color alteration caused by external stimuli (volatile organic compounds and mechanical grinding)...
  21. ncbi Sex determination: insights from the silkworm
    Masataka G Suzuki
    The Institute of Physical and Chemical Research, Hirosawa, Wako, Saitama 351 0198, Japan
    J Genet 89:357-63. 2010
    ..Since BmPSI does not exhibit any sequence relationship to known SR proteins, such as Tra and Tra2, the regulatory mechanism of sex-specific alternative splicing of Bmdsx is distinct from that of dsx...
  22. pmc GeneWaltz--A new method for reducing the false positives of gene finding
    Kazuharu Misawa
    Research Program for Computational Science, Research and Development Group for Next Generation Integrated Living Matter Simulation, Fusion of Data and Analysis Research and Development Team, RIKEN, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    BioData Min 3:6. 2010
    ..These false positives are problematic because they waste time and resources of experimental studies...
  23. doi Development of selective inhibitors of necrosis
    Mikiko Sodeoka
    RIKEN Advanced Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Chem Rec 10:308-14. 2010
    ..IM-54 inhibits necrosis induced by oxidative stress, but not apoptosis induced by anticancer drugs...
  24. doi DNA methylation profiling using live-cell imaging
    Kazuo Yamagata
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN Kobe, Minatojima minamimachi 2 2 3, Chuo Ku, Kobe City, Hyogo 651 0047, Japan
    Methods 52:259-66. 2010
    ..In this review, I describe the theoretical basis of this imaging and discuss its usefulness and potential for studies on epigenetic regulation, especially in early mammalian development...
  25. pmc Autonomous right-screw rotation of growth cone filopodia drives neurite turning
    Atsushi Tamada
    Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
    J Cell Biol 188:429-41. 2010
    ..Although the growth cone itself has been regarded as functionally symmetric, our study reveals the asymmetric nature of growth cone motility...
  26. doi sORF finder: a program package to identify small open reading frames with high coding potential
    Kousuke Hanada
    Plant Science Center, RIKEN, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    Bioinformatics 26:399-400. 2010
    ....
  27. doi Optimization of SSVEP brain responses with application to eight-command Brain-Computer Interface
    Hovagim Bakardjian
    Laboratory for Advanced Brain Signal Processing, Brain Science Institute, RIKEN, Wako Shi, Saitama, Japan
    Neurosci Lett 469:34-8. 2010
    ..These results emphasize the need for SSVEP applications to optimize not only the analysis algorithms but also the stimuli in order to maximize the brain responses they rely on...
  28. pmc NGSView: an extensible open source editor for next-generation sequencing data
    Erik Arner
    RIKEN Omics Science Center, RIKEN Yokohama Institute 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    Bioinformatics 26:125-6. 2010
    ..NGSView is available under an open source license and can be extended through a well documented API...
  29. doi Pd(0)-Mediated rapid coupling between methyl iodide and heteroarylstannanes: an efficient and general method for the incorporation of a positron-emitting (11)C radionuclide into heteroaromatic frameworks
    Masaaki Suzuki
    RIKEN Center for Molecular Imaging Science, 6 7 3 Minatojima minamimachi, Chuo Ku, Kobe 650 0047, Japan
    Chemistry 15:12489-95. 2009
    ....
  30. doi Relative importance of the tyrosine phosphorylation sites of Disabled-1 to the transmission of Reelin signaling
    Toshifumi Morimura
    Ogawa Research Unit, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Brain Res 1304:26-37. 2009
    ..The results also suggest that phosphorylation of either one of the residues in each pair is sufficient for the transmission of Reelin signaling...
  31. ncbi Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol
    Tadashi Suzuki
    Department of Biochemistry, 21st Center of Excellence Program, Osaka University Graduate School of Medicine, Japan
    Semin Cell Dev Biol 18:762-9. 2007
    ..Taken together, these observations indicate that C-terminus of mammalian PNGase is important for recognition of the substrates while N-terminus of this enzyme is involved in assembly of a degradation complex...
  32. ncbi Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions
    Naoya Hosono
    Laboratory for Genotyping, SNP Research Center, The Institute of Physical and Chemical Research RIKEN, Kanagawa, Japan
    Hum Mutat 29:182-9. 2008
    ..We believe mPCR-RETINA will provide a significant contribution to identifying functional alleles in CNV regions...
  33. pmc Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes
    Akiyoshi Uemura
    Laboratory for Stem Cell Biology, Center for Developmental Biology, Institute of Physical and Chemical Research RIKEN, Kobe, Japan
    J Clin Invest 116:369-77. 2006
    ..This work identifies Tlx as an essential component of the molecular network involved in the hypoxia-inducible proangiogenic switch in retinal astrocytes...
  34. ncbi Improved Golgi-like visualization in retrogradely projecting neurons after EGFP-adenovirus infection in adult rat and monkey
    Ryohei Tomioka
    Laboratory for Cortical Organization and Systematics, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    J Histochem Cytochem 54:539-48. 2006
    ..The native EGFP signal (without antibody enhancement) may be sufficient for studies involving cultured cells or slices...
  35. ncbi Raman probe using a single hollow waveguide
    Yuichi Komachi
    Probing Technology Laboratory, RIKEN, The Institute of Physical and Chemical Research, Hirosawa, Wako Shi 351 0198, Japan
    Opt Lett 30:2942-4. 2005
    ..In addition, the measured Raman spectra showed better signal-to-noise ratios than a conventional Raman fiber probe. The HW's suitability as a Raman fiber probe was also demonstrated...
  36. ncbi Robustness, evolvability, and optimality of evolutionary neural networks
    P P Palmes
    RIKEN Brain Science Institute, Hirosawa Wako City, Saitama 351 198, Japan
    Biosystems 82:168-88. 2005
    ..Our results strongly suggest that proper ANN design requires simultaneous adaptation of ANN structure and weights to avoid one-sided or bias convergence to either the weight or architecture space...
  37. ncbi Generation of progeny from embryonic stem cells by microinsemination of male germ cells from chimeric mice
    Eiji Mizutani
    Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN Kobe, Japan
    Genesis 43:34-42. 2005
    ..Thus, this technique allowed us to generate the ES cell-derived progeny even from the low contributed chimeric mice, which cannot produce ES-origin offspring by natural mating...
  38. ncbi Gene expression and association analyses of LIM (PDLIM5) in bipolar disorder and schizophrenia
    T Kato
    Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Wako Shi, Saitama, Japan
    Mol Psychiatry 10:1045-55. 2005
    ..No association was observed in case-control analysis and family-based association analysis in schizophrenia. These results suggest that SNPs in the upstream region of LIM may confer the genetic risk for bipolar disorder...
  39. ncbi Molecular phylogeny of parabasalids inferred from small subunit rRNA sequences, with emphasis on the Hypermastigea
    Moriya Ohkuma
    Environmental Molecular Biology Laboratory, RIKEN, Wako, Saitama 351 0198, Japan
    Mol Phylogenet Evol 35:646-55. 2005
    ..The monophyletic lineage composed by Spirotrichonymphida exhibited a narrower branching pattern than Trichonymphida. The root of parabasalids was examined but could not be discerned accurately...
  40. ncbi [Future views on genome network projects]
    Yoshihide Hayashizaki
    Tanpakushitsu Kakusan Koso 49:3017. 2004
  41. ncbi [Orthologue, paralogue and comparative genomics for gene network analysis]
    Nobuyuki Kawagashira
    Tanpakushitsu Kakusan Koso 49:2909-15. 2004
  42. ncbi [Protein-protein interaction assay by dual-color fluorescence cross correlation spectroscopy]
    Rieko Oyama
    Tanpakushitsu Kakusan Koso 49:2775-9. 2004
  43. ncbi Isofrequency band-like zones of activation revealed by optical imaging of intrinsic signals in the cat primary auditory cortex
    H Ojima
    Cortical Organization Systematics, BSI, RIKEN, 2 1 Hirosawa, Wako, Saitama, 351 0198 Japan
    Cereb Cortex 15:1497-509. 2005
    ....
  44. ncbi [Functional coupling between neuron and glia in neuronal sphingolipid biosynthesis]
    Yoshio Hirabayashi
    Tanpakushitsu Kakusan Koso 49:2391-6. 2004
  45. ncbi pDUAL, a multipurpose, multicopy vector capable of chromosomal integration in fission yeast
    Akihisa Matsuyama
    Chemical Genetics Laboratory, RIKEN, Saitama 351 0198, Japan
    Yeast 21:1289-305. 2004
    ..Using these all-in-one vectors, a suitable mode of expression of a cloned gene can be selected for individual analysis without any complicated subcloning processes...
  46. ncbi New methods to prepare iodinated derivatives by vaporizing iodine labelling (VIL) and hydrogen peroxide VIL (HYPER-VIL)
    Hideyuki Miyatake
    RIKEN Harima Institute SPring 8, Sayo cho, Sayo gun, Hyogo, Japan
    Acta Crystallogr D Biol Crystallogr 62:280-9. 2006
    ..The effectiveness of these techniques was assessed using five different crystals. Four of the crystals were successfully iodinated, providing sufficient phasing power for structure determination...
  47. ncbi Neural correlates of priming on occluded figure interpretation in human fusiform cortex
    L C Liu
    Laboratory for Human Brain Dynamics, RIKEN Brain Science Institute BSI, 2 1 Hirosawa, Wakoshi, Saitama 351 0198, Japan
    Neuroscience 141:1585-97. 2006
    ....
  48. ncbi Lipid rafts: new tools and a new component
    Toshihide Kobayashi
    Lipid Biology Laboratory, RIKEN Institute of Physical and Chemical Research, Japan
    Biol Pharm Bull 29:1526-31. 2006
    ..Recent findings have uncovered a previously unrecognized activity of a glycosphingolipid synthesis inhibitor, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP)...
  49. ncbi Notch: filling a hole in T helper 2 cell differentiation
    Masato Kubo
    Laboratory for Signal Network, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Suehiro cho 1 7 22, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Immunity 27:3-5. 2007
    ..In this issue of Immunity, Amsen et al. (2007) and Fang et al. (2007) propose a direct role for Notch signaling in the expression of GATA-3 transcription factor and T helper 2 cell differentiation...
  50. ncbi A novel dominant-negative mutation in Gdf5 generated by ENU mutagenesis impairs joint formation and causes osteoarthritis in mice
    Hiroshi Masuya
    Mouse Functional Genomics Research Group, RIKEN GSC, Tsukuba, Ibaraki, Japan
    Hum Mol Genet 16:2366-75. 2007
    ..This study further highlights a critical role of GDF5 in joint formation and the development of OA, and this mouse should serve as a good model for OA...
  51. ncbi Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family
    M Tomomura
    Laboratory for Molecular Neurogenesis, Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    Neuroscience 148:510-21. 2007
    ....
  52. ncbi Lymphocytic choriomeningitis infection undetected by dirty-bedding sentinel monitoring and revealed after embryo transfer of an inbred strain derived from wild mice
    Fumio Ike
    RIKEN BioResource Center, Tsukuba, Ibaraki, Japan
    Comp Med 57:272-81. 2007
    ..111..
  53. ncbi Simultaneous pattern classification and multidomain association using self-structuring kernel memory networks
    Tetsuya Hoya
    Department of Mathematics, College of Science and Technology, Nihon University, Tokyo 101 8308, Japan
    IEEE Trans Neural Netw 18:732-44. 2007
    ....
  54. pmc Two new non-competitive mGlu1 receptor antagonists are potent tools to unravel functions of this mGlu receptor subtype
    T Knopfel
    Laboratory for Neuronal Circuit Dynamics, RIKEN BSI, Wako Shi, Saitama, Japan
    Br J Pharmacol 151:723-4. 2007
    ....
  55. ncbi Dynamic functional connectivity
    Andreas A Ioannides
    Laboratory for Human Brain Dynamics, RIKEN Brain Science Institute, 2 1 Hirosawa, Wakoshi, Saitama, Japan 351 0198
    Curr Opin Neurobiol 17:161-70. 2007
    ..As shown at the end of this review, a correspondence principle can be formulated to guide the interpretation across network levels and to relate nodes to well defined anatomical entities...
  56. ncbi Mechanisms of COPII vesicle formation and protein sorting
    Ken Sato
    Molecular Membrane Biology Laboratory, RIKEN Discovery Research Institute, Hirosawa, Wako, Saitama 351 0198, Japan
    FEBS Lett 581:2076-82. 2007
    ..In the present review, we summarize current knowledge of COPII-mediated vesicle formation from the ER, as well as highlighting non-canonical roles of COPII components...
  57. ncbi Precise mapping of early visual responses in space and time
    Vahe Poghosyan
    Laboratory for Human Brain Dynamics, BSI, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama, 351 0198, Japan
    Neuroimage 35:759-70. 2007
    ..These results show for the first time in humans, significantly shorter onset latencies in V1 for peripheral than parafoveal VF stimulations...
  58. ncbi Molecular genetics of bipolar disorder and depression
    Tadafumi Kato
    Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Wako, Saitama, Japan
    Psychiatry Clin Neurosci 61:3-19. 2007
    ..Finally, this report addresses some possible causes for the lack of replication in this field...
  59. ncbi [ADLib system for rapid and flexible design of monoclonal antibodies]
    Kunihiro Ohta
    Genetic System Regulation Laboratory, RIKEN Discovery Research Institute, Wako City, Saitama, Japan
    Yakugaku Zasshi 127:81-9. 2007
    ..The ADLib system is applicable to self- or highly conserved antigens, polysaccharide chains, peptides, and haptens...
  60. ncbi Acid-base catalysis of chiral Pd complexes: development of novel catalytic asymmetric reactions and their application to synthesis of drug candidates
    Yoshitaka Hamashima
    Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi, Japan
    Chem Pharm Bull (Tokyo) 54:1351-64. 2006
    ..This aza-Michael reaction was successfully applied to asymmetric synthesis of the CETP inhibitor torcetrapib...
  61. ncbi Clathrin-associated adaptor protein complexes
    Hiroshi Ohno
    Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology RCAI, RIKEN, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Japan
    J Cell Sci 119:3719-21. 2006
  62. ncbi Identification of region-specific transcription factor genes in the adult mouse brain by medium-scale real-time RT-PCR
    Harukazu Suzuki
    Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences Center GSC, 1 7 22, Suehiro cho, Tsurumi ku, Yokohama 230 0045, Japan
    FEBS Lett 573:214-8. 2004
    ..These results provide unique molecular markers that may account for the molecular basis of the unique functions of specific brain regions...