Shuhei Nakanishi

Summary

Affiliation: Radiation Effects Research Foundation
Country: Japan

Publications

  1. ncbi request reprint Relation between QT duration and mortality in an elderly Japanese population
    Shuhei Nakanishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Am J Cardiol 93:1182-5. 2004
  2. ncbi request reprint Relationship between development of diabetes and family history by gender in Japanese-Americans
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Res Clin Pract 61:109-15. 2003
  3. ncbi request reprint Elevated C-reactive protein is a risk factor for the development of type 2 diabetes in Japanese Americans
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Care 26:2754-7. 2003
  4. ncbi request reprint The effect of polymorphism in the intestinal fatty acid-binding protein 2 gene on fat metabolism is associated with gender and obesity amongst non-diabetic Japanese-Americans
    S Nakanishi
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Obes Metab 6:45-9. 2004
  5. ncbi request reprint A protective effect of adiponectin against oxidative stress in Japanese Americans: the association between adiponectin or leptin and urinary isoprostane
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Metabolism 54:194-9. 2005
  6. ncbi request reprint Increasing of oxidative stress from mitochondria in type 2 diabetic patients
    Shuhei Nakanishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Diabetes Metab Res Rev 20:399-404. 2004
  7. ncbi request reprint Relationship between HbA(1)c and mortality in a Japanese population
    S Nakanishi
    Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima 732 0815, Japan
    Diabetologia 48:230-4. 2005
  8. ncbi request reprint Prevalence of metabolic syndrome compared between native Japanese and Japanese-Americans
    Masayasu Yoneda
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Diabetes Res Clin Pract 79:518-22. 2008
  9. ncbi request reprint Serum leptin and adiponectin are positively associated with bone mineral density at the distal radius in patients with type 2 diabetes mellitus
    Tomoko Tamura
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Metabolism 56:623-8. 2007
  10. ncbi request reprint Associations between small dense LDL, HDL subfractions (HDL2, HDL3) and risk of atherosclerosis in Japanese-Americans
    Shusaku Maeda
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    J Atheroscler Thromb 19:444-52. 2012

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Relation between QT duration and mortality in an elderly Japanese population
    Shuhei Nakanishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Am J Cardiol 93:1182-5. 2004
    ..Even in Japanese subjects, who have a lower coronary heart disease rate than that of Caucasians, the careful observation of subjects with a prolonged QTc is believed to be necessary...
  2. ncbi request reprint Relationship between development of diabetes and family history by gender in Japanese-Americans
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Res Clin Pract 61:109-15. 2003
    ..Our findings suggest that even if lifestyle is westernized, a family history of diabetes is an important predictor of type 2 diabetes development especially among women in Japanese-American population...
  3. ncbi request reprint Elevated C-reactive protein is a risk factor for the development of type 2 diabetes in Japanese Americans
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Care 26:2754-7. 2003
    ..However, Japanese subjects are skewed to lower CRP concentrations than westerners. Therefore, the effect of CRP on the development of type 2 diabetes among Japanese is unclear...
  4. ncbi request reprint The effect of polymorphism in the intestinal fatty acid-binding protein 2 gene on fat metabolism is associated with gender and obesity amongst non-diabetic Japanese-Americans
    S Nakanishi
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Diabetes Obes Metab 6:45-9. 2004
    ..Assuming that the effects of the polymorphism were modulated by gender and obesity which were related to lipid and glucose metabolism, we investigated this polymorphism and its effect on fat metabolism according to such factors...
  5. ncbi request reprint A protective effect of adiponectin against oxidative stress in Japanese Americans: the association between adiponectin or leptin and urinary isoprostane
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Metabolism 54:194-9. 2005
    ..These results also suggest the possibility that adiponectin might modulate oxidative stress, leading to antidiabetic and anti-arteriosclerotic effects...
  6. ncbi request reprint Increasing of oxidative stress from mitochondria in type 2 diabetic patients
    Shuhei Nakanishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Diabetes Metab Res Rev 20:399-404. 2004
    ..Mitochondria has received much attention as an important organ in the generation of oxidative stress. However, the importance of oxidative stress among diabetic patients without vascular complications is unclear...
  7. ncbi request reprint Relationship between HbA(1)c and mortality in a Japanese population
    S Nakanishi
    Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima 732 0815, Japan
    Diabetologia 48:230-4. 2005
    ..However, the relationship has not been clarified well in the Japanese. In addition, studies of the relationship between HbA(1)c and mortality from malignant neoplasms are scarce...
  8. ncbi request reprint Prevalence of metabolic syndrome compared between native Japanese and Japanese-Americans
    Masayasu Yoneda
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Diabetes Res Clin Pract 79:518-22. 2008
    ..This report demonstrates that a westernization of lifestyle can increase the prevalence of metabolic syndrome among Japanese-Americans as compared to native Japanese...
  9. ncbi request reprint Serum leptin and adiponectin are positively associated with bone mineral density at the distal radius in patients with type 2 diabetes mellitus
    Tomoko Tamura
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Metabolism 56:623-8. 2007
    ..No correlation was observed between serum adiponectin and serum osteocalcin or urinary NTX. These results indicate that leptin and adiponectin may have a protective effect on bone metabolism in patients with type 2 diabetes mellitus...
  10. ncbi request reprint Associations between small dense LDL, HDL subfractions (HDL2, HDL3) and risk of atherosclerosis in Japanese-Americans
    Shusaku Maeda
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    J Atheroscler Thromb 19:444-52. 2012
    ....
  11. ncbi request reprint Effects of a westernized lifestyle on the association between fasting serum nonesterified fatty acids and insulin secretion in Japanese men
    Nozomu Kamei
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734 8551, Japan
    Metabolism 54:713-8. 2005
    ..A westernized lifestyle may increase the effects of serum fasting NEFA levels on total insulin secretion after a glucose load in Japanese men...
  12. ncbi request reprint Effectiveness of Semmes-Weinstein monofilament examination for diabetic peripheral neuropathy screening
    Nozomu Kamei
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    J Diabetes Complications 19:47-53. 2005
    ..To evaluate the effectiveness of the Semmes-Weinstein monofilament examination (SWME) for diabetic peripheral neuropathy (DPN) screening at an outpatient clinic...
  13. ncbi request reprint Decreased total and high molecular weight adiponectin are independent risk factors for the development of type 2 diabetes in Japanese-Americans
    Reiko Nakashima
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi Minami ku, Hiroshima City 734 8551, Japan
    J Clin Endocrinol Metab 91:3873-7. 2006
    ..Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic adipokine. Adiponectin exists as multimers in plasma, and high molecular weight (HMW) adiponectin is particularly thought to be the active form of the protein...
  14. ncbi request reprint [Macroangiopathy compared between native Japanese and Japanese-Americans: findings from the Hawaii-Los Angels-Hiroshima Study]
    Masatoshi Hirano
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
    Nihon Rinsho 68:857-60. 2010
    ..The mortality rate of Japanese-Americans with diabetes from ischemic heart disease increased to be similar extent to that of Caucasian in the U.S. It could be concluded that Japanese-Americans are at high risk for macroangiopathy...
  15. ncbi request reprint Resistance to thyroid hormone accompanied by Graves' disease
    Tsuguka Shiwa
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Japan
    Intern Med 50:1977-80. 2011
    ..The finding of an elevated TSH level without decreased thyroid hormones should suggest the presence of RTH during therapy of Graves' disease...
  16. ncbi request reprint HLA haplotype is associated with diabetes among atomic bomb survivors
    Tomonori Hayashi
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan
    Hum Immunol 64:910-6. 2003
    ..These results suggest that individuals with specific HLA haplotypes may have an increased risk of diabetes with increased-dose categories...
  17. ncbi request reprint Association of Chlamydia pneumoniae infection and carotid intima-media wall thickness in Japanese Americans
    Kuniaki Jitsuiki
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Hiroshima University, Hiroshima, Japan
    Circ J 70:815-9. 2006
    ..Chlamydia pneumoniae (Cp) infection has been proposed as a risk factor for coronary artery disease (CAD), but it remains unclear whether Cp plays a role in the progression of early stage carotid atherosclerosis...
  18. ncbi request reprint A case of polyglandular autoimmune syndrome type III complicated with autoimmune hepatitis
    Kenji Oki
    Department of Molecular and Internal Medicine, Graduate School Biomedical Sciences, Hiroshima University, Kasumi, Hiroshima, Japan
    Endocr J 53:705-9. 2006
    ..Although it is common for patients with Graves' disease to exhibit abnormal liver function, it is important to make an accurate diagnosis of AIH because of this life-threatening disorder...
  19. doi request reprint Improvement of hypercortisolism by β-blocker therapy in subclinical Cushing's syndrome associated with ACTH-independent macronodular adrenocortical hyperplasia
    Kenji Oki
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3 Kasumi, Minami Ku, Hiroshima City, Hiroshima 734 8551, Japan
    Endocrine 36:372-6. 2009
    ..Additional cases or controlled studies are needed to determine the potential effect of propranolol on metabolic disorders and adrenal size in patients with AIMAH...
  20. doi request reprint Aldosterone synthase (CYP11B2) C-344T polymorphism affects the association of age-related changes of the serum C-reactive protein
    Kenji Oki
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
    Hypertens Res 33:326-30. 2010
    ..028). The CC genotype of the CYP11B2 C-344T polymorphism was associated with an age-dependent increase in the serum CRP level independent of BP, and may contribute to a cardiovascular phenotype by promoting vascular inflammation...
  21. ncbi request reprint [International comparison of morbidity in diabetes and IGT]
    Shuhei Nakanishi
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University
    Nihon Rinsho 63:67-71. 2005
  22. ncbi request reprint Anti-Ku antibody-positive scleroderma-dermatomyositis overlap syndrome developing Graves' disease and immune thrombocytopenic purpura
    Nozomu Kamei
    Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima
    Intern Med 41:1199-203. 2002
    ..The patient was anti-Ku antibody-positive and had relatively low natural killer T cell counts, both of which might contribute to the complication of multiple autoimmune diseases...
  23. ncbi request reprint Circulating aminopeptidase N/CD13 is an independent prognostic factor in patients with non-small cell lung cancer
    Haruyasu Murakami
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, and The Fifth Department of Oncology, Kitano Hospital, Osaka, Japan
    Clin Cancer Res 11:8674-9. 2005
    ..The aim of this study was to evaluate the clinical significance of circulating aminopeptidase N/CD13 protein detected by mAb MH8-11 in patients with non-small cell lung cancer (NSCLC)...