M Ozawa

Summary

Country: Japan

Publications

  1. ncbi request reprint Altered cell adhesion activity by pervanadate due to the dissociation of alpha-catenin from the E-cadherin.catenin complex
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Biol Chem 273:6166-70. 1998
  2. pmc The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Biol 142:1605-13. 1998
  3. ncbi request reprint Tyrosine phosphorylation of p120(ctn) in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Sci 114:503-12. 2001
  4. ncbi request reprint Identification of the region of alpha-catenin that plays an essential role in cadherin-mediated cell adhesion
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Biol Chem 273:29524-9. 1998
  5. ncbi request reprint The fourth armadillo repeat of plakoglobin (gamma-catenin) is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor suppressor APC protein
    M Ozawa
    Department of Biochemistry, Kagoshima University
    J Biochem 118:1077-82. 1995
  6. ncbi request reprint Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1)
    Y Adachi
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan
    Oncogene 13:2197-203. 1996
  7. pmc Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis
    S Matsubara
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Biol 154:573-84. 2001
  8. ncbi request reprint Isolation and characterization of mucinlike glycoprotein associated with photoreceptor cells
    F Uehara
    Department of Ophthalmology, Kagoshima University, Faculty of Medicine, Kagoshima shi, Japan
    Invest Ophthalmol Vis Sci 41:2759-65. 2000
  9. ncbi request reprint Myocardial infarction induces expression of midkine, a heparin-binding growth factor with reparative activity
    H Obama
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan
    Anticancer Res 18:145-52. 1998
  10. ncbi request reprint Identification of the domain of alpha-catenin involved in its association with beta-catenin and plakoglobin (gamma-catenin)
    H Obama
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890, Japan
    J Biol Chem 272:11017-20. 1997

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Altered cell adhesion activity by pervanadate due to the dissociation of alpha-catenin from the E-cadherin.catenin complex
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
    J Biol Chem 273:6166-70. 1998
    ....
  2. pmc The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Biol 142:1605-13. 1998
    ..Therefore, the membrane-proximal region participates in regulation of the adhesive activity by preventing lateral dimerization of the extracellular domain...
  3. ncbi request reprint Tyrosine phosphorylation of p120(ctn) in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Sci 114:503-12. 2001
    ..These results indicate that tyrosine phosphorylation of p120(ctn) is involved in the v-Src modulation of E-cadherin-mediated cell adhesion...
  4. ncbi request reprint Identification of the region of alpha-catenin that plays an essential role in cadherin-mediated cell adhesion
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Biol Chem 273:29524-9. 1998
    ....
  5. ncbi request reprint The fourth armadillo repeat of plakoglobin (gamma-catenin) is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor suppressor APC protein
    M Ozawa
    Department of Biochemistry, Kagoshima University
    J Biochem 118:1077-82. 1995
    ....
  6. ncbi request reprint Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1)
    Y Adachi
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan
    Oncogene 13:2197-203. 1996
    ..The evidence reported in this study indicates that MK gene is a newly identified WT1 target gene...
  7. pmc Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis
    S Matsubara
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Cell Biol 154:573-84. 2001
    ..We postulate that alpha-catenin mediates transduction of signals from the cadherin-catenin complex to regulate the apoptotic cascade via p27kip1...
  8. ncbi request reprint Isolation and characterization of mucinlike glycoprotein associated with photoreceptor cells
    F Uehara
    Department of Ophthalmology, Kagoshima University, Faculty of Medicine, Kagoshima shi, Japan
    Invest Ophthalmol Vis Sci 41:2759-65. 2000
    ..In this study, cloning of the O-linked glycoproteins not only in the IPM but also in the region including the cone pedicles and rod spherules was attempted...
  9. ncbi request reprint Myocardial infarction induces expression of midkine, a heparin-binding growth factor with reparative activity
    H Obama
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan
    Anticancer Res 18:145-52. 1998
    ..The induced MK expression is likely to mimic the expression during embryogenesis: MK was strong lye-expressed in the myocytes of embryonic heart, and the expression decreased during embryogenesis...
  10. ncbi request reprint Identification of the domain of alpha-catenin involved in its association with beta-catenin and plakoglobin (gamma-catenin)
    H Obama
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, 8 35 1 Sakuragaoka, Kagoshima 890, Japan
    J Biol Chem 272:11017-20. 1997
    ..7 x 10(-8), respectively). When transfected into L cells expressing E-cadherin, the amino-terminal region of alpha-catenin (from residue 1 to 226) formed complexes with beta-catenin supporting the in vitro binding experiment results...
  11. ncbi request reprint Cloning of a human homologue of mouse reticulocalbin reveals conservation of structural domains in the novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University
    J Biochem 117:1113-9. 1995
    ..The conservation of the HDEL sequence in reticulocalbin in both species raises the possibility that this sequence has some roles in the function(s) of this protein family...
  12. ncbi request reprint Molecular cloning and expression of a mouse alpha-1,3 fucosyltransferase gene that shows homology with the human alpha-1,3 fucosyltransferase IV gene
    M Ozawa
    Department of Biochemistry, Kagoshima University
    J Biochem 119:302-8. 1996
    ....
  13. ncbi request reprint Cloning of an alternative form of plakoglobin (gamma-catenin) lacking the fourth armadillo repeat
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University
    J Biochem 118:836-40. 1995
    ..Therefore the variant form is most likely derived through alternative splicing of precursor RNA transcripts in an exon sequence...
  14. ncbi request reprint p120(ctn) binds to the membrane-proximal region of the E-cadherin cytoplasmic domain and is involved in modulation of adhesion activity
    T Ohkubo
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Kagoshima 890 8520, Japan
    J Biol Chem 274:21409-15. 1999
    ..Together, these results indicate that p120(ctn) is a modulator of E-cadherin-mediated cell adhesion...
  15. ncbi request reprint Midkine (MK) expression in extraembryonic tissues, amniotic fluid, and cerebrospinal fluid during mouse embryogenesis
    H Obama
    Department of Biochemistry, Faculty of Medicine, Kagoshima University
    J Biochem 118:88-93. 1995
    ..Transport of MK from the site of its synthesis appears to also occur in the adult kidney, since MK mRNA and the MK protein are localized in different regions of the kidney...
  16. ncbi request reprint Structure of the gene encoding mouse reticulocalbin, a novel endoplasmic reticulum-resident Ca(2+)-binding protein with multiple EF-hand motifs
    M Ozawa
    Department of Biochemistry, Faculty of Medicine, Kagoshima University
    J Biochem 118:154-60. 1995
    ..Comparison of the gene organization of reticulocalbin with that of other EF-hand proteins revealed that reticulocalbin diverged very early from other members of the EF-hand protein super-family...
  17. ncbi request reprint cDNA cloning and sequence analysis of a novel calcium binding protein with oligoproline motif
    S Yu
    Department of Biochemistry, Faculty of Medicine, Kagoshima University, Japan
    Cell Struct Funct 20:263-8. 1995
    ..The cDNA was translated as a fusion protein with glutathione-S-transferase, and was verified to have calcium binding activity, upon a calcium blot experiment...