Yasushi Oshima

Summary

Country: Japan

Publications

  1. doi request reprint Effect of light-emitting diode (LED) therapy on the development of osteoarthritis (OA) in a rabbit model
    Yasushi Oshima
    Department of Orthopaedic Surgery, University of California San Diego, La Jolla CA 92093 0863, USA
    Biomed Pharmacother 65:224-9. 2011
  2. ncbi request reprint Fate of transplanted bone-marrow-derived mesenchymal cells during osteochondral repair using transgenic rats to simulate autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 602 8566 Japan
    Osteoarthritis Cartilage 12:811-7. 2004
  3. ncbi request reprint Behavior of transplanted bone marrow-derived GFP mesenchymal cells in osteochondral defect as a simulation of autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Histochem Cytochem 53:207-16. 2005
  4. doi request reprint Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 215:837-45. 2008
  5. doi request reprint Antiapoptotic molecule Bcl-2 is essential for the anabolic activity of parathyroid hormone in bone
    Yuichi Nagase
    Department of Orthopaedic Surgery, University of Tokyo, Tokyo, Japan
    Ann N Y Acad Sci 1192:330-7. 2010
  6. pmc Anti-apoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts
    Yuichi Nagase
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Biol Chem 284:36659-69. 2009
  7. ncbi request reprint GFP chimeric models exhibited a biphasic pattern of mesenchymal cell invasion in tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 210:684-91. 2007
  8. doi request reprint Is a right pedicle screw always away from the aorta in scoliosis?
    Katsushi Takeshita
    Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan
    Spine (Phila Pa 1976) 36:E1519-24. 2011
  9. pmc Variation of mesenchymal cells in polylactic acid scaffold in an osteochondral repair model
    Yasushi Oshima
    Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA 92093 0630, USA
    Tissue Eng Part C Methods 15:595-604. 2009
  10. doi request reprint Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6
    Tetsuro Yasui
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Bone Miner Res 26:1447-56. 2011

Collaborators

Detail Information

Publications26

  1. doi request reprint Effect of light-emitting diode (LED) therapy on the development of osteoarthritis (OA) in a rabbit model
    Yasushi Oshima
    Department of Orthopaedic Surgery, University of California San Diego, La Jolla CA 92093 0863, USA
    Biomed Pharmacother 65:224-9. 2011
    ..The objective of this study was to evaluate whether light-emitting diodes (LEDs) could be effective in a noninvasive, therapeutic device for the treatment of osteoarthritic (OA) knee joints...
  2. ncbi request reprint Fate of transplanted bone-marrow-derived mesenchymal cells during osteochondral repair using transgenic rats to simulate autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 602 8566 Japan
    Osteoarthritis Cartilage 12:811-7. 2004
    ..With this aim in view, the survival of transplanted bone-marrow-derived mesenchymal cells within osteochondral defects was determined using transgenic rats to simulate autologous transplantation...
  3. ncbi request reprint Behavior of transplanted bone marrow-derived GFP mesenchymal cells in osteochondral defect as a simulation of autologous transplantation
    Yasushi Oshima
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Histochem Cytochem 53:207-16. 2005
    ....
  4. doi request reprint Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 215:837-45. 2008
    ..These findings suggest that locally injected PRP is useful as an activator of circulation-derived cells for enhancement of the initial tendon healing process...
  5. doi request reprint Antiapoptotic molecule Bcl-2 is essential for the anabolic activity of parathyroid hormone in bone
    Yuichi Nagase
    Department of Orthopaedic Surgery, University of Tokyo, Tokyo, Japan
    Ann N Y Acad Sci 1192:330-7. 2010
    ..Interestingly, the anabolic effect of parathyroid hormone (PTH) was not observed in Bcl-2(-/-)Bim(+/-) mice. This data demonstrates that Bcl-2 is indispensable for the anabolic activity of PTH in bone...
  6. pmc Anti-apoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts
    Yuichi Nagase
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Biol Chem 284:36659-69. 2009
    ..The balance between Bcl-2 and Bim regulates osteoclast apoptosis and function, whereas other pro-apoptotic members are important for osteoblasts...
  7. ncbi request reprint GFP chimeric models exhibited a biphasic pattern of mesenchymal cell invasion in tendon healing
    Yoshiteru Kajikawa
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Cell Physiol 210:684-91. 2007
    ..These findings suggest that circulation-derived and tendon-derived cells contribute to the healing of tendons in different periods as part of a biphasic process...
  8. doi request reprint Is a right pedicle screw always away from the aorta in scoliosis?
    Katsushi Takeshita
    Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan
    Spine (Phila Pa 1976) 36:E1519-24. 2011
    ..Retrospective analysis...
  9. pmc Variation of mesenchymal cells in polylactic acid scaffold in an osteochondral repair model
    Yasushi Oshima
    Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA 92093 0630, USA
    Tissue Eng Part C Methods 15:595-604. 2009
    ..The objectives of this study were to elucidate the survival of mesenchymal cells (MCs). In a polylactic acid (PLA) scaffold and assess the possibility of MC/PLA constructs for osteochondral repair...
  10. doi request reprint Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6
    Tetsuro Yasui
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Bone Miner Res 26:1447-56. 2011
    ..In summary, TGF-β is indispensable in RANKL-induced osteoclastogenesis, and the binding of Smad3 to the TRAF6-TAB1-TAK1 complex is crucial for RANKL-induced osteoclastogenic signaling...
  11. pmc The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice
    Mitsuyasu Iwasawa
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    J Clin Invest 119:3149-59. 2009
    ....
  12. doi request reprint In vivo effects of ovarian steroid hormones on the expressions of estrogen receptors and the composition of extracellular matrix in the anterior cruciate ligament in rats
    Atsuhiko Yoshida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Connect Tissue Res 50:121-31. 2009
    ..These findings suggest that ACL is ER-dependent and that ovarian hormones alter ligament tissue composition, especially at the proximal portion. Female hormonal influences are partly involved in the biological properties of ACL...
  13. doi request reprint Natural course and prognostic factors in patients with mild cervical spondylotic myelopathy with increased signal intensity on T2-weighted magnetic resonance imaging
    Yasushi Oshima
    Department of Orthopaedic Surgery, The University of Tokyo, Bunkyo ku, Japan
    Spine (Phila Pa 1976) 37:1909-13. 2012
    ..A retrospective comparative study...
  14. ncbi request reprint Behavior of graft and host cells in underlying subchondral bone after transplantation of osteochondral autograft
    Yasushi Oshima
    Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
    Microsc Res Tech 58:19-24. 2002
    ..The two models of the transplantations using the transgenic rats were found to be beneficial in following graft cells as well as host cells and in understanding their function on healing after autologous transplantation...
  15. doi request reprint Bone marrow-derived cells from the footprint infiltrate into the repaired rotator cuff
    Yoshikazu Kida
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Shoulder Elbow Surg 22:197-205. 2013
    ..Cells from the bone marrow are considered important during the rotator cuff repair process, but the kinetics of bone marrow-derived cells in this process is unknown...
  16. pmc Use of bone morphogenic protein-7 as a treatment for osteoarthritis
    Neil Badlani
    Department of Orthopaedic Surgery, University of California, San Diego, 9500 Gilman Drive, Mail Code 0630, La Jolla, CA 92093 0630, USA
    Clin Orthop Relat Res 467:3221-9. 2009
    ..These results indicate bone morphogenic protein-7 may reduce degradation of articular cartilage in osteoarthritis...
  17. ncbi request reprint The fate of host and graft cells in early healing of bone tunnel after tendon graft
    Masashi Kobayashi
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto 602 8566, Japan
    Am J Sports Med 33:1892-7. 2005
    ..The behavior of host and graft cells during the healing process after autologous tendon graft has not been elucidated...
  18. ncbi request reprint Ossification of the posterior atlantoaxial membrane associated with an os odontoideum: a case report
    Junichi Ohya
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Orthop Surg (Hong Kong) 19:392-4. 2011
    ..Long-standing atlantoaxial instability might have played a role in ectopic ossification of the posterior atlantoaxial membrane...
  19. pmc Validity and reliability of the Japanese version of the painDETECT questionnaire: a multicenter observational study
    Yoshitaka Matsubayashi
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 8:e68013. 2013
    ..The aim of this study was to evaluate the validity and reliability of the Japanese version of the painDETECT questionnaire (PDQ-J)...
  20. ncbi request reprint Tumor necrosis factor-alpha inhibits chondrogenic differentiation of synovial fibroblasts through p38 mitogen activating protein kinase pathways
    Chiaki Okuma-Yoshioka
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Mod Rheumatol 18:366-78. 2008
    ..Combination therapy BMP-2 and anti-TNF-alpha agents especially targeting p38 MAPK might be a good approach to stimulating neochondrogenesis in the damaged joints in RA...
  21. doi request reprint Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis
    Chiaki Okuma
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    J Bone Miner Metab 26:576-85. 2008
    ..Using this model, we found the possible involvement of p53 in the osteocyte apoptosis observed in ION. Therapeutics targeting p53 might be a useful approach to ameliorating or even preventing osteonecrosis in ION patients...
  22. doi request reprint Use of Doppler ultrasonography to detect an elusive communication of a spinal extradural arachnoid cyst
    Masakazu Kanetaka
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    J Clin Neurosci 18:863-4. 2011
    ..Doppler ultrasonography may be a helpful adjunct for identifying the location of elusive communication in a spinal extradural arachnoid cyst...
  23. doi request reprint Validity, reliability and responsiveness of the Japanese version of the Neck Disability Index
    Katsushi Takeshita
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Orthop Sci 18:14-21. 2013
    ..The Neck Disability Index (NDI) is one of the most widely used questionnaires for neck pain. The purpose of this study was to validate the Japanese NDI...
  24. doi request reprint Clinical usefulness of thallium-201 scintigraphy and magnetic resonance imaging in the diagnosis of chondromyxoid fibroma
    Hiroaki Murata
    Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
    Ann Nucl Med 22:221-4. 2008
    ..Contrast-enhanced MR imaging and thallium-201 scintigraphy may be useful to distinguish CMF from benign bone tumors or chondrosarcoma...
  25. pmc Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis
    Yasushi Oshima
    Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Biol Chem 283:26499-508. 2008
    ..These results suggest the pivotal role of Bcl-2 family members in the regulation of chondrocyte apoptosis...
  26. doi request reprint Aorta movement in patients with scoliosis after posterior surgery
    Katsushi Takeshita
    Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan
    Spine (Phila Pa 1976) 35:E1571-6. 2010
    ..Retrospective analysis...