Affiliation: Osaka University
Tsujikawa K, Ichijo T, Moriyama K, Tadotsu N, Sakamoto K, Sakane N, et al
. Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule. Mol Cancer Res. 2002;1:155-63 pubmed
..Our results indicate that Lck and Fyn would be substrates of LAR in immature thymocytes and that each LAR PTPase domain plays distinct functional roles in phosphorylation and dephosphorylation. ..
Tsujikawa K, Yayama K, Hayashi T, Matsushita H, Yamaguchi T, Shigeno T, et al
. Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice. Proc Natl Acad Sci U S A. 2007;104:16702-7 pubmed
..These results indicate that CGRP signaling through CLR/RAMP1 receptors plays a crucial role in the regulation of both blood pressure by vascular relaxation and proinflammatory cytokine production from dendritic cells. ..
Tsujikawa K, Kawakami N, Uchino Y, Ichijo T, Furukawa T, Saito H, et al
. Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor. Mol Endocrinol. 2001;15:271-80 pubmed
..These results indicate that each domain of LAR plays distinct functional roles through phosphorylation and dephosphorylation in vivo. ..
Tsujikawa K, Koike K, Kitae K, Shinkawa A, Arima H, Suzuki T, et al
. Expression and sub-cellular localization of human ABH family molecules. J Cell Mol Med. 2007;11:1105-16 pubmed
..In some HeLa cells transfected with EmGFP-hABH5, dot-like fluorescence was also detected in the cytoplasm. These observations provide important information for the future annotation of the hABH family of molecules. ..