Takuji Tomimatsu

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. ncbi request reprint Effects of neonatal hypoxic-ischemic brain injury on skilled motor tasks and brainstem function in adult rats
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Osaka University School of Medicine, 2 2, Yamada oka, Suita, Osaka, Japan
    Brain Res 926:108-17. 2002
  2. ncbi request reprint Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease
    T Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, Osaka 565 0871, Japan
    Neurosci Lett 312:21-4. 2001
  3. ncbi request reprint Long-term neuroprotective effects of hypothermia on neonatal hypoxic-ischemic brain injury in rats, assessed by auditory brainstem response
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, Osaka, 565 0871, Japan
    Pediatr Res 53:57-61. 2003
  4. ncbi request reprint Effects of hyperthermia on hypoxic-ischemic brain damage in the immature rat: its influence on caspase-3-like protease
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Japan
    Am J Obstet Gynecol 188:768-73. 2003
  5. ncbi request reprint Neonatal Bartter syndrome with unilateral multicystic dysplastic kidney disease
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, 565 0871, Osaka, Japan
    Pediatr Nephrol 18:391-3. 2003
  6. ncbi request reprint Apoptosis and related proteins in placenta of intrauterine fetal death in prostaglandin f receptor-deficient mice
    Junwu Mu
    Department of Obstetrics and Gynecology, Osaka University, Faculty of Medicine, Osaka, Japan
    Biol Reprod 68:1968-74. 2003
  7. doi request reprint Maternal carbon dioxide level during labor and its possible effect on fetal cerebral oxygenation: mini review
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    J Obstet Gynaecol Res 39:1-6. 2013
  8. ncbi request reprint Postischemic hyperthermia induced caspase-3 activation in the newborn rat brain after hypoxia-ischemia and exacerbated the brain damage
    Hirotsugu Fukuda
    Department of Obstetrics and Gynecology, Osaka University School of Medicine, 2 2 Yamada Oka Suita, Osaka 565 0871, Japan
    Biol Neonate 84:164-71. 2003
  9. doi request reprint The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Obstet Gynecol 203:364.e6-364.e12. 2010
  10. ncbi request reprint Relationship between human tumor-associated antigen RCAS1 and gestational diabetes mellitus
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 58:440-6. 2007

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Effects of neonatal hypoxic-ischemic brain injury on skilled motor tasks and brainstem function in adult rats
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Osaka University School of Medicine, 2 2, Yamada oka, Suita, Osaka, Japan
    Brain Res 926:108-17. 2002
    ..The present study shows that both the staircase test and ABR are sensitive and objective long-term neurofunctional measurements that can be used in future studies to assess therapeutic intervention in this neonatal cerebral H-I model...
  2. ncbi request reprint Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease
    T Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, Osaka 565 0871, Japan
    Neurosci Lett 312:21-4. 2001
    ....
  3. ncbi request reprint Long-term neuroprotective effects of hypothermia on neonatal hypoxic-ischemic brain injury in rats, assessed by auditory brainstem response
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, Osaka, 565 0871, Japan
    Pediatr Res 53:57-61. 2003
    ..The current study demonstrates that postischemic hypothermia may provide effective and long-lasting neurofunctional as well as histopathologic protection to the immature brain...
  4. ncbi request reprint Effects of hyperthermia on hypoxic-ischemic brain damage in the immature rat: its influence on caspase-3-like protease
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Japan
    Am J Obstet Gynecol 188:768-73. 2003
    ....
  5. ncbi request reprint Neonatal Bartter syndrome with unilateral multicystic dysplastic kidney disease
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, 2 2, Yamada oka, Suita, 565 0871, Osaka, Japan
    Pediatr Nephrol 18:391-3. 2003
    ..In this paper, we report a case of neonatal Bartter syndrome associated with unilateral multicystic dysplastic kidney disease. To our knowledge, this is the first case report of such an association...
  6. ncbi request reprint Apoptosis and related proteins in placenta of intrauterine fetal death in prostaglandin f receptor-deficient mice
    Junwu Mu
    Department of Obstetrics and Gynecology, Osaka University, Faculty of Medicine, Osaka, Japan
    Biol Reprod 68:1968-74. 2003
    ..Thus, significantly increased apoptosis in the mouse placenta and decidua might be involved in the pathophysiologic mechanism of intrauterine fetal death...
  7. doi request reprint Maternal carbon dioxide level during labor and its possible effect on fetal cerebral oxygenation: mini review
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    J Obstet Gynaecol Res 39:1-6. 2013
    ..Thus, maternal hyperventilation may interfere with optimal fetal cerebral oxygenation. Here, we provide a brief overview of the literature relevant to this issue...
  8. ncbi request reprint Postischemic hyperthermia induced caspase-3 activation in the newborn rat brain after hypoxia-ischemia and exacerbated the brain damage
    Hirotsugu Fukuda
    Department of Obstetrics and Gynecology, Osaka University School of Medicine, 2 2 Yamada Oka Suita, Osaka 565 0871, Japan
    Biol Neonate 84:164-71. 2003
    ..Our results show that postischemic hyperthermia exacerbates HI injury in immature brains, and that the mechanism is strongly associated with activation of an apoptotic pathway...
  9. doi request reprint The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Obstet Gynecol 203:364.e6-364.e12. 2010
    ..We hypothesized that RCAS1 protein gene silencing might affect blood pressure and proteinuria in pregnant mice...
  10. ncbi request reprint Relationship between human tumor-associated antigen RCAS1 and gestational diabetes mellitus
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 58:440-6. 2007
    ....
  11. ncbi request reprint Long-term neuroprotective effects of carbon dioxide on neonatal rat hypoxic-ischemic brain injury: an experimental study of skilled motor tasks
    Masatomo Kohzuki
    Department of Obstetrics and Gynecology Osaka University Faculty of Medicine, Suita City, Osaka, Japan
    Am J Obstet Gynecol 195:240-5. 2006
    ..This study was undertaken to investigate the long-term effect of hypercapnia on neonatal hypoxic-ischemic brain injury, we tested its effect in a neonatal rat hypoxia-ischemia model...
  12. doi request reprint Maternal blood serum and plasma human tumor-associated antigen RCAS1 during the course of uncomplicated pregnancies: a prospective study
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 64:218-24. 2010
    ..we aimed to investigate the expression of the tumor-associated RCAS1 protein in maternal blood of uncomplicated pregnancies...
  13. doi request reprint Hypoxic preconditioning increases triiodothyronine (T3) level in the developing rat brain
    Kenji Minato
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Brain Res 1501:89-97. 2013
    ..The present study indicates that thyroid hormones and their associated molecules may be involved in neuroprotective mechanisms of HPC during the developmental period...
  14. doi request reprint Maternal hyperventilation during labor revisited: its effects on fetal oxygenation
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan
    Reprod Sci 19:1169-74. 2012
    ..62, P < .001), and UVHb(O2) values (r = .59, P < .001). Maternal hyperventilation had a close relationship with lower UVP(CO2), UVP(O2), and UVHbo(2) values, which might interfere with optimal fetal cerebral oxygenation...
  15. doi request reprint Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 63:137-43. 2010
    ..The aim of our study was to investigate the expression of RCAS1 protein in the uteri of normal pregnant mice...
  16. doi request reprint Nicotine suppresses interleukin-6 production from vascular endothelial cells: a possible therapeutic role of nicotine for preeclampsia
    Namuxila Sharentuya
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Reprod Sci 17:556-63. 2010
    ..Nicotine inhibited inflammatory reaction through NF-kB suppression in vitro model of maternal vascular endothelium, and this effect may be one of the explanations for the reduced risk of preeclampsia in smokers...
  17. ncbi request reprint Normalisation of angiogenic imbalance after intra-uterine transfusion for mirror syndrome caused by parvovirus B19
    Satoko Goa
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    Fetal Diagn Ther 34:176-9. 2013
    ..This suggests that the sFlt-1/PlGF ratio may help to predict the post-treatment course of mirror syndrome. ..
  18. doi request reprint Pseudomyxoma peritonei originating from colorectal cancer during pregnancy
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 37:254-8. 2011
    ....
  19. doi request reprint Human C-reactive protein enhances vulnerability of immature rats to hypoxic-ischemic brain damage: a preliminary study
    Yukiko Kinugasa-Taniguchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Reprod Sci 17:419-25. 2010
    ..C-reactive protein makes the immature brain susceptible to HI insult, even if the insult causes little or no injury by itself...
  20. ncbi request reprint Apoptosis and related proteins during parturition in prostaglandin F receptor-deficient mice
    Junwu Mu
    Department of Obstetrics and Gynecology, Radiation Biology, Faculty of Medicine, Osaka University, 2 2 Yamadaoka Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 292:675-81. 2002
    ..These findings demonstrate that apoptosis, Fas, FasL, caspase-3, and Bcl-2 occur in mouse term placenta that is not involved in parturition...
  21. doi request reprint Ceftriaxone preconditioning confers neuroprotection in neonatal rats through glutamate transporter 1 upregulation
    Kazuya Mimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Reprod Sci 18:1193-201. 2011
    ..This study investigated the hypothesis that ceftriaxone preconditioning ameliorates brain damage in neonatal animals through glutamate transporter 1 (GLT-1) upregulation...
  22. doi request reprint Effects of 4-hydroxy-2-nonenal, a major lipid peroxidation-derived aldehyde, and N-acetylcysteine on the cyclooxygenase-2 expression in human uterine myometrium
    Kumiko Temma-Asano
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Gynecol Obstet Invest 72:37-42. 2011
    ..We also examined the effect of N-acetylcysteine (NAC) on 4-HNE-induced COX-2 expression...
  23. doi request reprint Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in an in vitro model of preeclamptic vascular endothelium: a possible therapeutic role of nicotinic acetylcholine receptor (nAChR) agonists for preeclampsia
    Kazuya Mimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Am J Obstet Gynecol 202:464.e1-6. 2010
    ..In this study we tested the hypothesis that nicotine restores proangiogenic functions to endothelial cells pretreated with soluble fms-like tyrosine kinase 1 and/or soluble endoglin...
  24. ncbi request reprint Level of S100B protein expression in the amnion at various gestational ages in the third trimester of normal pregnancies
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Acta Obstet Gynecol Scand 86:915-20. 2007
    ..The aim of our study was to assess the correlation between S100B protein expression in the amnion, amniotic fluid and gestational age in the third trimester of uncomplicated pregnancies...
  25. doi request reprint Central aortic blood pressure and augmentation index during normal pregnancy
    Mika Fujime
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    Hypertens Res 35:633-8. 2012
    ..These data may be used as the basis for further investigation into the role of pulse wave analysis in the assessment, management and prediction of disorders, which might interfere with pregnancy-related cardiovascular adaptations...
  26. doi request reprint Balloon tamponade during cesarean section is useful for severe post-partum hemorrhage due to placenta previa
    Takako Ishii
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    J Obstet Gynaecol Res 38:102-7. 2012
    ..The aim of this study was to evaluate the efficiency of intrauterine tamponade with a Sengstaken-Blakemore tube (SB-tube) for the treatment of severe post-partum hemorrhage in cases of placenta previa...
  27. doi request reprint A case of complete hydatidiform mole with coexistent fetus: conclusive diagnosis of androgenesis of the molar placenta by variation of paternal acrocentric short arms
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Am J Perinatol 27:143-9. 2010
    ..We describe the clinical course of our case and review some literature concerning complete hydatidiform mole with coexisting fetus...
  28. ncbi request reprint Cervical insufficiency following cesarean delivery after prolonged second stage of labor: experiences of two cases
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan
    J Obstet Gynaecol Res 36:411-3. 2010
    ..Our report highlights the need to alert obstetricians to take more care with their cesarean section technique...
  29. pmc The amnioscope strikes back as a useful device for pinhole amniotomy in the management of polyhydramnios
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    AJP Rep 1:99-104. 2011
    ..In this pilot clinical study, we identified a new value for the amnioscope as a promising device for safer amniotomy in women with polyhydramnios...
  30. doi request reprint Successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor: the first case report in Japan
    Shinsuke Koyama
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 37:1711-6. 2011
    ..She delivered a 2882-g healthy infant in October 2010. Pregnancy after simultaneous pancreas-kidney transplantation is discussed...
  31. ncbi request reprint Investigation of intraplacental villous arteries by Doppler flow imaging in growth-restricted fetuses
    Junwu Mu
    Department of Obstetrics and Gynecology, Osaka University, Faculty of Medicine, Japan
    Am J Obstet Gynecol 186:297-302. 2002
    ....
  32. ncbi request reprint Umbilical cord ulcer associated with fetal jejunal atresia: report of 2 cases
    Takuya Kimura
    Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Fetal Diagn Ther 18:144-7. 2003
    ..In such cases, detailed examination of the umbilical cord by ultrasonography may be useful for the prenatal diagnosis of this disease...
  33. ncbi request reprint The effects of repeated corticosteroid administration on the neurogenesis in the neonatal rat
    Takeshi Kanagawa
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Osaka, Japan
    Am J Obstet Gynecol 194:231-8. 2006
    ..The purpose of this study is to clarify the effects on the brain including neurogenesis pretreated with repeated doses of dexamethasone in the neonatal rat...
  34. doi request reprint Reliable predictors of neonatal immune thrombocytopenia in pregnant women with idiopathic thrombocytopenic purpura
    Shinsuke Koyama
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Japan
    Am J Hematol 87:15-21. 2012
    ..Management decisions, including mode of delivery, may be altered by the degree of risk for potentially severe NITP...
  35. doi request reprint Molecular analysis of parturition via oxytocin receptor expression
    Tadashi Kimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Taiwan J Obstet Gynecol 52:165-70. 2013
    ..Recent progress in molecular biology has augmented our knowledge about OTR regulation in the uterus at the transcription level, although the totality of preparation for labor through OTR expression is still obscure. ..
  36. doi request reprint Fetal and neonatal anemia associated with anti-Jr(a) : a case report showing a poorly hemolytic mechanism
    Naoko Sasamoto
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 37:1132-6. 2011
    ..9 mg/dL) and reticulocyte counts (4.5%) were low. During the course, the infant showed no apparent signs of hemolysis. Jr(a) alloimmunization should be recognized as a possible cause of fetal anemia with no direct hemolytic process...
  37. ncbi request reprint Fetal cerebral oxygenation: the role of maternal hyperoxia with supplemental CO2 in sheep
    Takuji Tomimatsu
    Center for Perinatal Biology and the Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA
    Am J Obstet Gynecol 196:359.e1-5. 2007
    ..We tested the hypothesis that supplemental CO2 can enhance the effect of maternal oxygen administration on fetal cerebral oxygenation...
  38. ncbi request reprint Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats
    Kouji Wakayama
    Department of Advanced Clinical Science and Therapeutics, Graduate School of Medicine, The University of Tokyo, Japan
    Brain Res 1130:181-7. 2007
    ..Thus, the Montoya staircase test and methamphetamine-induced rotation are useful to evaluate neurological deficit in the chronic stage of subcortical infarction induced by 30-min tMCAo...