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Genomes and GenesSpecies | Akihiro TamoriSummaryAffiliation: Osaka City University Country: Japan Publications
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Publications
HBV DNA integration and HBV-transcript expression in non-B, non-C hepatocellular carcinoma in JapanAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
J Med Virol 71:492-8. 2003..These results suggested that occult HBV infection might play an important role in hepatocarcinogenesis in non-B, non-C patients with anti-HBc and that excessive alcohol intake might be related to HCC in non-B, non-C patients in Japan...
Expression of connective tissue growth factor in the human liver with idiopathic portal hypertensionHiroyasu Morikawa
Department of Hepatology, Osaka City University Graduate School of Medicine, Asahimachi, Osaka, Japan
Mol Med 13:240-5. 2007..Six (8%) of the 76 patients with IPH had serum CTGF levels greater than 80 ng/mL, far exceeding the level of any patient with cirrhosis. In conclusion, overexpression of CTGF is one of the most important features of IPH...
Add-on combination therapy with adefovir dipivoxil induces renal impairment in patients with lamivudine-refractory hepatitis B virusA Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
J Viral Hepat 17:123-9. 2010..However, the dosing interval of ADV should be adjusted according to renal function and serum phosphate levels in patients receiving long-term treatment...- Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseasesAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Liver Int 27:95-100. 2007..We investigated the genotypic status of TPMT to evaluate the risk of azathioprine-related adverse effects in Japanese patients with different liver diseases, including autoimmune hepatitis (AIH)... - Alteration of gene expression in human hepatocellular carcinoma with integrated hepatitis B virus DNAAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Clin Cancer Res 11:5821-6. 2005..This study attempted to find the link between HBV DNA, the adjoining cellular sequence, and altered gene expression in hepatocellular carcinoma (HCC) with integrated HBV DNA... - Prospective study of reactivation of hepatitis B virus in patients with rheumatoid arthritis who received immunosuppressive therapy: evaluation of both HBsAg-positive and HBsAg-negative cohortsAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
J Gastroenterol 46:556-64. 2011..This study also evaluated guidelines for determining HBV reactivation in patients with RA... - Frequent detection of hepatitis B virus DNA in hepatocellular carcinoma of patients with sustained virologic response for hepatitis C virusAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
J Med Virol 81:1009-14. 2009..Mutation in 'a' determinant of HBsAg was found in three HCC of group A. Occult HBV infection may be one of the most important risk factors in hepatocarcinogenesis of Japanese patients with sustained virologic response... - Hepatitis B virus DNA integration in hepatocellular carcinoma after interferon-induced disappearance of hepatitis C virusAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Am J Gastroenterol 100:1748-53. 2005..At chromosome 11q12, HBV DNA was integrated into protein-coding genome, the function of which remains unclear. CONCLUSION: Integrated HBV DNA may play a role in hepatocarcinogenesis after the clearance of HCV by IFN treatment... - Sequencing of human-viral DNA junctions in hepatocellular carcinoma from patients with HCV and occult HBV infectionAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Japan
J Med Virol 69:475-81. 2003..In conclusion, integrated HBV was detected in some patients with HCV infection; in these patients, the integrated DNA was associated with accelerated hepatocarcinogenesis... - Differences in molecular alterations of hepatocellular carcinoma between patients with a sustained virological response and those with hepatitis C virus infectionTakehiro Hayashi
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Liver Int 29:126-32. 2009..We compared molecular alterations in hepatocellular carcinoma (HCC) between patients with a sustained virological response (SVR) to IFN and patients with HCV... - Mutational patterns of hepatitis B virus genome and clinical outcomes after emergence of drug-resistant variants during lamivudine therapy: analyses of the polymerase gene and full-length sequencesMasaru Enomoto
Department of Hepatology, Osaka City University Medical School, Asahimachi, Abeno Ku, Osaka, Japan
J Med Virol 79:1664-70. 2007..In conclusion, mutational patterns of HBV DNA at the time of emergence of YMDD variants were apparently unrelated to the clinical outcomes in Japanese patients with chronic hepatitis B during lamivudine therapy... - Chemiluminescence enzyme immunoassay for monitoring hepatitis C virus core protein during interferon-alpha2b and ribavirin therapy in patients with genotype 1 and high viral loadsMasaru Enomoto
Department of Hepatology, Osaka City University Medical School, Osaka, Japan
J Med Virol 77:77-82. 2005..13 log10/day) than in 13 patients with no response (0.028 log10/day, P = 0.042). The wide linear range of the HCV core protein assay is appropriate for measuring viral loads during therapy with IFN-alpha and ribavirin... - Quantitative detection of hepatitis B surface antigen by chemiluminescent microparticle immunoassay during lamivudine treatment of chronic hepatitis B virus carriersMadoka Kohmoto
Department of Hepatology, Osaka City University Medical School, Abeno-ku, Osaka, Japan
J Med Virol 75:235-9. 2005.... - Effect of mosapride citrate on gastric emptying in interferon-induced gastroparesisEtsushi Kawamura
Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
Dig Dis Sci 57:1510-6. 2012..Current therapeutic options are limited. We evaluated the efficacy of mosapride for IFN-induced gastroparesis... - p16 promoter hypermethylation in human hepatocellular carcinoma with or without hepatitis virus infectionTakashi Narimatsu
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Intervirology 47:26-31. 2004..CONCLUSIONS: Our results suggest that hepatitis viruses might induce methylation of p16 promoter in liver with chronic inflammation, before appearance of HCC... - Clinical role of FDG-PET for HCC: relationship of glucose metabolic indicator to Japan Integrated Staging (JIS) scoreEtsushi Kawamura
Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
Hepatogastroenterology 55:582-6. 2008.... - Accurate prediction of response to interferon therapy by repeated measurement of hepatitis C virus core protein in patients with chronic hepatitis CShuhei Nishiguchi
Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
Intervirology 45:105-10. 2002..0-4.5 months before and just before the start of IFN therapy, and were tested for HCV core protein by a fluorescent enzyme immunoassay... - Dynamics of hepatitis C virus monitored by real-time quantitative polymerase chain reaction during first 2 weeks of IFN-beta treatment are predictive of long-term therapeutic responseMasaru Enomoto
Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan
J Interferon Cytokine Res 22:389-95. 2002..09 log10/day in nonresponders. We conclude that during the first 2 weeks of therapy, changes in serum HCV RNA levels as monitored by real-time quantitative PCR can be used to predict the long-term response to treatment with IFN-beta... - Lamivudine and IFN-beta sequential therapy in HBe antigen-positive patients with chronic hepatitis B virus genotype C infectionMasaru Enomoto
Department of Hepatology, Osaka City University Medical School, Osaka 545 8585, Japan
J Interferon Cytokine Res 27:201-7. 2007..Patients who were young or who had a favorable virologic response to lamivudine were more likely to have a sustained response... - Real-time tissue elastography as a tool for the noninvasive assessment of liver stiffness in patients with chronic hepatitis CHiroyasu Morikawa
Department of Hepatology, Graduate School of Medicine, Osaka City University, 1 4 3 Asahimachi, Abeno, Osaka 545 8585, Japan
J Gastroenterol 46:350-8. 2011.... - Effect of long-term postoperative interferon therapy on intrahepatic recurrence and survival rate after resection of hepatitis C virus-related hepatocellular carcinomaShuhei Nishiguchi
Department of Hepatology, Osaka City University Medical School, Osaka, Japan
Intervirology 48:71-5. 2005..This study was aimed at evaluating the effects of interferon (IFN)-alpha on survival rate after resection of hepatocellular carcinoma... - Noninvasive laboratory tests proposed for predicting cirrhosis in patients with chronic hepatitis C are also useful in patients with non-alcoholic steatohepatitisHideki Fujii
Department of Hepatology, Graduate School of Medicine, Osaka City University, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
J Gastroenterol 44:608-14. 2009..We assessed whether noninvasive laboratory tests designed to predict the risk of cirrhosis in patients with chronic hepatitis C virus (HCV) infection could be used in patients with NASH... - Comparison of the effect of BCAA granules on between decompensated and compensated cirrhosisDaiki Habu
Department of Hepatology, Graduate School of Medicine, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
Hepatogastroenterology 56:1719-23. 2009.... - Polyamine metabolism and recurrence after resection for hepatocellular carcinomaShoji Kubo
Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
Hepatogastroenterology 51:208-10. 2004..We investigated the relationship between polyamine metabolism in hepatocellular carcinoma tissues and the recurrence after resection of hepatocellular carcinoma... - Role of vitamin K2 in the development of hepatocellular carcinoma in women with viral cirrhosis of the liverDaiki Habu
Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
JAMA 292:358-61. 2004..13 (95% CI, 0.02-0.99; P =.05). CONCLUSION: There is a possible role for vitamin K2 in the prevention of hepatocellular carcinoma in women with viral cirrhosis... - Hepatitis B virus genotypes and response to antiviral therapyMasaru Enomoto
Department of Hepatology, Osaka City University Medical School, Osaka, Japan
Clin Lab 52:43-7. 2006..Determining the genotype could be helpful for predicting the outcome of antiviral therapy in patients with chronic hepatitis B... - Hepatocellular carcinoma (HCC) recurring 10 years after clearance of hepatitis B surface antigen and 20 years after resection of hepatitis B virus-related HCCHiroji Shinkawa
Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, 545 8585, Japan
Int J Clin Oncol 13:562-6. 2008..Cassette-ligation-mediated PCR showed that HBV DNA was integrated into the telomerase reverse transcriptase gene located on chromosome 5p15... - Vitamin K2 (menatetrenone) for bone loss in patients with cirrhosis of the liverSusumu Shiomi
Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
Am J Gastroenterol 97:978-81. 2002..017). No adverse effects of vitamin K2 were noted. CONCLUSIONS: Vitamin K2 can prevent bone loss and may therefore be useful in the management of bone disease in women with cirrhosis of the liver... - Does a late evening meal reduce the risk of hepatocellular carcinoma among patients with chronic hepatitis C?Satoko Ohfuji
Department of Public Health, Osaka City University Graduate School of Medicine, Osaka, Japan
Hepatol Res 38:860-8. 2008..Further studies with larger study sizes are needed to corroborate these findings... - A randomized pilot trial of oral branched-chain amino acids in early cirrhosis: validation using prognostic markers for pre-liver transplant statusEtsushi Kawamura
Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan
Liver Transpl 15:790-7. 2009..4% (7 of 23 patients) at 3 years, P = 0.043]; only ascites was significant individually. In conclusion, early interventional oral BCAAs might prolong the liver transplant waiting period by preserving hepatic reserve in cirrhosis... - Optimal duration of additional therapy after biochemical and virological responses to lamivudine in patients with HBeAg-negative chronic hepatitis B: a randomized trialMasaru Enomoto
Department of Hepatology, Graduate School of Medicine, Osaka City University Medical School, Osaka, Japan
Hepatol Res 38:954-9. 2008.... - Cimetidine reduces impairment of cellular immunity after transcatheter arterial embolization in patients with hepatocellular carcinomaShuhei Nishiguchi
Department of Hepatology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan
Hepatogastroenterology 50:460-2. 2003..032). CONCLUSIONS: Our study raises the possibility that cimetidine has the effect to preserve cell-mediated immune response during transcatheter arterial embolization... - Usefulness of per-rectal portal scintigraphy with technetium-99m pertechnetate for prognosis of primary biliary cirrhosisShuhei Nishiguchi
Department of Hepatology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585 Osaka, Japan
Hepatogastroenterology 50:1783-6. 2003.... - Close correlation of liver stiffness with collagen deposition and presence of myofibroblasts in non-alcoholic fatty liver diseaseMami Mori
Department of Hepatology, Graduate School of Medicine, Osaka City University Central Clinical Laboratory, Osaka City University Medical School Hospital, Osaka, Japan
Hepatol Res 41:897-903. 2011..390, P = 0.0184) and α-smooth muscle actin-positive area (r = 0.333, P = 0.0471). Conclusions: Liver stiffness measurement by transient elastography is valuable for evaluating fibrotic progression in NAFLD... - Emerging antiviral drugs for hepatitis C virusMasaru Enomoto
Department of Hepatology, Osaka City University Medical School, Osaka, Japan
Rev Recent Clin Trials 4:179-84. 2009..Herein we review recent progress in the development of new treatments under investigation in clinical trials, including specifically targeted antiviral therapy for HCV such as NS3/4A protease and NS5B polymerase inhibitors... - Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinomaAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan
J Gastroenterol 39:1063-8. 2004..The accumulation of mtDNA mutations is a useful predictor of hepatocarcinogenesis... - GB virus C and TT virus infections in Japanese patients with autoimmune hepatitisShuhei Nishiguchi
Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
J Med Virol 66:258-62. 2002..These findings provide no compelling evidence that GBV-C or TTV has a pathogenic role in autoimmune hepatitis... - [Epidemiology of HBV related hepatocellular carcinoma in Japan]Shuhei Nishiguchi
Department of Hepatology, Osaka City University Graduate School of Medicine
Nippon Rinsho 62:377-80. 2004 - Successful treatment of giant rectal varices by modified percutaneous transhepatic obliteration with sclerosant: Report of a caseHirotoshi Okazaki
Department of Gastroenterology, Osaka City University Graduate School of Medicine, 1-4-3, Asahimachi, Abeno-ku, Osaka, Japan
World J Gastroenterol 12:5408-11. 2006..After the patient received this therapy, her condition of rectal varices was markedly improved... - Benefits of artificially induced pleural effusion and/or ascites for percutaneous radiofrequency ablation of hepatocellular carcinoma located on the liver surface and in the hepatic domeShuji Iwai
Department of Hepatology, Osaka City University, Osaka, Japan
Hepatogastroenterology 59:546-50. 2012..However, the indication of this technique is unclear and its therapeutic efficacy is undetermined... - [Interferon]Akihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine
Nihon Rinsho 70:620-4. 2012..Maintenance therapy with low dose of PEG-IFN or IFN can improve the prognosis of patients with advanced hepatic fibrosis... - Response-guided therapy for patients with chronic hepatitis who have high viral loads of hepatitis C virus genotype 2Yasunori Yamaguchi
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Hepatol Res 42:549-57. 2012..Conclusions: 16 weeks of combination therapy could achieve an adequate antiviral effect for RVR patients. Extending therapy could not significantly improve SVR rate in non-RVR patients... - A case of primary small cell carcinoma of the liver that was treated with chemotherapyHiroyasu Morikawa
Department of Hepatology, Graduate School of Medicine, Osaka City University, 1 4 3, Asahimachi, Abeno, Osaka, 545 8585, Japan
Hepatol Int 2:500-4. 2008..We discuss the clinical course and therapy of extra-pulmonary SCC and review the literature of the cases previously reported... - Pretreatment prediction of anemia progression by pegylated interferon alpha-2b plus ribavirin combination therapy in chronic hepatitis C infection: decision-tree analysisNaoki Hiramatsu
Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan
J Gastroenterol 46:1111-9. 2011..This study aimed to develop a model to predict the development of severe anemia during pegylated interferon alpha-2b plus ribavirin combination therapy... - Usefulness of transient elastography for assessment of liver fibrosis in chronic hepatitis B: Regression of liver stiffness during entecavir therapyMasaru Enomoto
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Hepatol Res 40:853-61. 2010..7) to 3.9 (3.2-4.4) ng/mL (P = 0.015), respectively. Conclusion: Liver stiffness measurement can be useful for monitoring regression of liver fibrosis during entecavir treatment in patients with chronic hepatitis B virus infection... - Portal vein thrombosis following percutaneous ethanol injection therapy for hepatocellular carcinomaDaiki Habu
Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan
Indian J Gastroenterol 21:162-3. 2002..She developed portal vein thrombosis that on color Doppler revealed no tumor vascular signal, and so was diagnosed as non-tumor thrombus. The thrombus resolved over 3 months... - Ultrasonographic diagnosis of degree of chronic type C liver diseaseDaiki Habu
Department of Hepatology, Graduate School of Medicine, Osaka City University Medical School, Japan
Hepatogastroenterology 52:1820-4. 2005..We propose a method, named US score, for semi-quantitative determination of the stage of chronic type C liver disease by ultrasonography... - Effects of lamivudine on outcome after liver resection for hepatocellular carcinoma in patients with active replication of hepatitis B virusShoji Kubo
Departments of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
Hepatol Res 37:94-100. 2007.... - Changes in sequences of core region, interferon sensitivity-determining region and interferon and ribavirin resistance-determining region of hepatitis C virus genotype 1 during interferon-alpha and ribavirin therapy, and efficacy of retreatmentRitsuzo Kozuka
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka Center for the Advancement of Higher Education, Faculty of Engineering, Kinki University, Hiroshima, Japan
Hepatol Res 42:1157-67. 2012..Conclusion: Sequences of the core region and ISDR sometimes change during anti-HCV therapy, potentially affecting the outcomes of retreatment... - [Drug-induced liver injury caused by an herbal medicine, bofu-tsu-sho-san]Hiroyuki Motoyama
Department of Hepatology, Graduate School of Medicine, Osaka City University, Japan
Nihon Shokakibyo Gakkai Zasshi 105:1234-9. 2008..The liver biopsy specimen revealed features of acute hepatitis. Physicians should be aware that bofu-tsu-sho-san can cause liver injury, as this drug is commonly used as an over-the-counter medicine... - Two cases of hepatocellular adenomatosis treated with transcatheter arterial embolizationSawako Kobayashi
Department of Hepatology, Graduate School of Medicine, Osaka City University, 1 4 3, Asahimachi, Abeno, Osaka, 545 8585, Japan
Hepatol Int 3:416-20. 2009..After TAE, most parts of the adenomas showed necrotic change. These cases suggest that TAE is an effective treatment of hepatocellular adenomatosis... - Favorable factors for re-treatment with pegylated interferon α2a plus ribavirin in patients with high viral loads of genotype 1 hepatitis C virusAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine Department of Hepatology Osaka City General Hospital Department of Gastroenterology and Hepatology, Osaka City Juso Hospital, Osaka Internal Medicine, Izumi Municipal Hospital, Izumi Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Hepatol Res 41:1169-77. 2011..Re-treatment is a particularly useful option for patients who achieve early viral clearance during previous therapy... - High prevalence of hepatitis C virus infection in Airin district, Osaka, Japan: A hospital-based study of 1162 patientsYasunori Yamaguchi
Departments of Hepatology Gastroenterology, Graduate School of Medicine, Osaka City University Department of Internal Medicine, Osaka Socio Medical Center Hospital Izumi Municipal Hospital, Izumi, Osaka, Japan
Hepatol Res 41:731-7. 2011..Patient education and strict action against illegal drug use are indispensable to prevent the spread of HCV infection from the district... - Erythrocyte-binding polyamine as a tumor growth marker for human hepatocellular carcinomaShuhei Nishiguchi
Third Department of Internal Medicine, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
Hepatogastroenterology 49:504-7. 2002..Concentrations of polyamines are higher in some cancer tissue than in normal tissue. We examined erythrocyte-binding polyamines to evaluate the usefulness of polyamines as pathophysiological markers for hepatocellular carcinoma... - A case of sclerosing cholangitis with autoimmune pancreatitis evaluated by FDG-PETEtsushi Kawamura
Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
Ann Nucl Med 21:223-8. 2007.... - [Prevalence and clinical course in HBV and HCV dual chronic infection]Akihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine
Nippon Rinsho 62:667-70. 2004 - Potential role of vitamin K(2) as a chemopreventive agent against hepatocellular carcinomaAkihiro Tamori
Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
Hepatol Res 37:S303-7. 2007..This article reviews the potential role of vitamin K(2) as a chemopreventive agent against HCC and discusses future directions for clinical trials... - Randomized trial assessing gastric emptying in patients with chronic hepatitis C during interferon-alpha or -beta therapy and effect of cisaprideShuhei Nishiguchi
Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
Dig Dis Sci 47:73-8. 2002..Interferon-alpha is associated with a greater delay in gastric emptying and a higher symptom score than is interferon-beta. Administration of cisapride corrects the delayed gastric emptying and relieves associated digestive symptoms... - Esophagogastric varices due to arterioportal shunt in a serous cystadenoma of the pancreas in von Hippel-Lindau diseaseMasatsugu Okuyama
Department of Gastroenterology, Osaka City University Medical School, Osaka, Japan
Dig Dis Sci 48:1948-54. 2003..Rupture of esophageal varices was successfully treated with endoscopic injection sclerotherapy... - Previous or occult hepatitis B virus infection in hepatitis B surface antigen-negative and anti-hepatitis C-negative patients with hepatocellular carcinomaKazuki Ohba
Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan
Surg Today 34:842-8. 2004..CONCLUSION: These findings suggested that previous or occult hepatitis B virus infection is common in HBsAg-negative and anti-HCV-negative patients with HCC... - Serial changes in expression of functionally clustered genes in progression of liver fibrosis in hepatitis C patientsYoshiyuki Takahara
Exploratory and Applied Pharmaceutical Research Department, Pharmaceutical Company, Ajinomoto Co, Inc, 1 1 Suzuki cho, Kawasaki ku, Kawasaki 210 8681, Japan
World J Gastroenterol 14:2010-22. 2008.... - Changes in serum levels of hepatitis C virus genotype 1b monitored by real-time quantitative polymerase chain reaction as a predictor of long term response to interferon-alpha treatmentMasaru Enomoto
Third Department of Internal Medicine and Second Department of Biochemistry, Osaka City University Medical School, Japan
Am J Gastroenterol 97:420-6. 2002..CONCLUSIONS: Changes in serum levels of HCV genotype 1b in the first 2 wk of interferon-alpha treatment, monitored by real-time quantitative PCR, can be used for prediction of the long term therapeutic response... - Disease associations and altered immune function in CD45 138G variant carriersSally Boxall
The Edward Jenner Institute for Vaccine Research, Compton, Berkshire RG20 7NN, UK
Hum Mol Genet 13:2377-84. 2004..These data suggest that the 138G variant allele strongly influences these diseases by modulation of immune mechanisms and may have achieved its high frequency as a result of a natural selection probably related to pathogen resistance... - [Present status of community-based HCV screening in Osaka City and evaluation of the utility of follow-up programs on hepatitis]Kenji Matsumoto
Asahi Ward Health and Welfare Center, Osaka City
Nihon Koshu Eisei Zasshi 55:75-82. 2008..The present status of community-based HCV screening in Osaka City and the utility of follow-up programs on hepatitis were examined... - Geographical distribution and disease associations of the CD45 exon 6 138G variantVictoria Ward
Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, Cancer Research UK, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
Immunogenetics 58:235-9. 2006..The allele is widely distributed in the Far East and India, indicating that it may have a significant effect on disease burden in a large part of the human population...