Shigeo Takenaka

Summary

Affiliation: Osaka Prefecture University
Country: Japan

Publications

  1. ncbi request reprint Feeding dried purple laver (nori) to vitamin B12-deficient rats significantly improves vitamin B12 status
    S Takenaka
    Laboratory of Nutrition and Food Science, Hagoromo gakuen College, Sakai 592 8344, Japan
    Br J Nutr 85:699-703. 2001
  2. ncbi request reprint Occurrence of coenzyme forms of vitamin B12 in a cultured purple laver (Porphyla yezoensis)
    Shigeo Takenaka
    Department of Veterinary Sciences, Osaka Prefecture University, Sakai, Japan
    Biosci Biotechnol Biochem 67:2480-2. 2003
  3. pmc Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives
    Tsutomu Shimada
    Laboratory of Cellular and Molecular Biology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1 58 Rinku Orai Kita, Izumisano, Osaka 598 8531, Japan
    Chem Res Toxicol 23:1921-35. 2010
  4. ncbi request reprint Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors
    Toshihiko Tanno
    Laboratory of Cellular and Molecular Biology, Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    J Vet Med Sci 68:1173-7. 2006
  5. ncbi request reprint Expression patterns of the BRCA1 splicing variants in canine normal tissues and mammary gland tumors
    Takaaki Sugiura
    Laboratory of Veterinary Radiology, Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
    J Vet Med Sci 69:587-92. 2007
  6. doi request reprint Urinary metabolic fingerprinting for alpha-naphthylisothiocyanate-induced intrahepatic cholestasis in rats using Fourier transform-ion cyclotron resonance mass spectrometry
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
    Toxicol Pathol 36:818-26. 2008
  7. doi request reprint Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury
    Yoko Mori
    Laboratories of Veterinary Pathology and Molecular Science, Life and Environmental Sciences, Osaka Prefecture University, Nakaku, Sakai, Osaka, Japan
    Toxicol Pathol 37:463-73. 2009
  8. ncbi request reprint Molecular characterization of a bifunctional glyoxylate cycle enzyme, malate synthase/isocitrate lyase, in Euglena gracilis
    Masami Nakazawa
    Department of Applied Biological Chemistry, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Comp Biochem Physiol B Biochem Mol Biol 141:445-52. 2005
  9. doi request reprint Alternations of phospholipid profile in placenta of streptozotocin-induced diabetic rat
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    Congenit Anom (Kyoto) 51:174-6. 2011
  10. ncbi request reprint Slit3 regulates cell motility through Rac/Cdc42 activation in lipopolysaccharide-stimulated macrophages
    Toshihiko Tanno
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    FEBS Lett 581:1022-6. 2007

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Feeding dried purple laver (nori) to vitamin B12-deficient rats significantly improves vitamin B12 status
    S Takenaka
    Laboratory of Nutrition and Food Science, Hagoromo gakuen College, Sakai 592 8344, Japan
    Br J Nutr 85:699-703. 2001
    ..These results indicate that vitamin B12 in dried purple laver is bioavailable to rats...
  2. ncbi request reprint Occurrence of coenzyme forms of vitamin B12 in a cultured purple laver (Porphyla yezoensis)
    Shigeo Takenaka
    Department of Veterinary Sciences, Osaka Prefecture University, Sakai, Japan
    Biosci Biotechnol Biochem 67:2480-2. 2003
    ..Coenzyme forms of vitamin B(12) (about 60% of the total vitamin B(12)) were found in the cultured purple laver aseptically, which may have the ability to biosynthesize the coenzymes...
  3. pmc Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives
    Tsutomu Shimada
    Laboratory of Cellular and Molecular Biology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1 58 Rinku Orai Kita, Izumisano, Osaka 598 8531, Japan
    Chem Res Toxicol 23:1921-35. 2010
    ....
  4. ncbi request reprint Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors
    Toshihiko Tanno
    Laboratory of Cellular and Molecular Biology, Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    J Vet Med Sci 68:1173-7. 2006
    ..These results suggest that the expression of slit2 plays an important role in tumor angiogenesis in canine mammary gland tumors and that slit2 can be a putative marker for malignancy diagnosis of these tumors...
  5. ncbi request reprint Expression patterns of the BRCA1 splicing variants in canine normal tissues and mammary gland tumors
    Takaaki Sugiura
    Laboratory of Veterinary Radiology, Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
    J Vet Med Sci 69:587-92. 2007
    ..Especially, the relative amounts of the exon11-defecting products were remarkably decreased in most of the tumors (11/16)...
  6. doi request reprint Urinary metabolic fingerprinting for alpha-naphthylisothiocyanate-induced intrahepatic cholestasis in rats using Fourier transform-ion cyclotron resonance mass spectrometry
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
    Toxicol Pathol 36:818-26. 2008
    ..In conclusion, it is possible to monitor the progression of and recovery from drug-induced hepatotoxicity by urinary metabolic fingerprinting with FT-ICR MS and to search for potential biomarkers involved in intrahepatic cholestasis...
  7. doi request reprint Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury
    Yoko Mori
    Laboratories of Veterinary Pathology and Molecular Science, Life and Environmental Sciences, Osaka Prefecture University, Nakaku, Sakai, Osaka, Japan
    Toxicol Pathol 37:463-73. 2009
    ..Collectively, macrophages in acute hepatic necrosis may express different properties such as phagocytosis, MHC class II expression, and TGF-beta1 production; such expression may be influenced by MCP-1 produced by HSCs...
  8. ncbi request reprint Molecular characterization of a bifunctional glyoxylate cycle enzyme, malate synthase/isocitrate lyase, in Euglena gracilis
    Masami Nakazawa
    Department of Applied Biological Chemistry, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Comp Biochem Physiol B Biochem Mol Biol 141:445-52. 2005
    ..We discussed the physiological roles of the bifunctional glyoxylate cycle enzyme in these organisms as well as its molecular evolution...
  9. doi request reprint Alternations of phospholipid profile in placenta of streptozotocin-induced diabetic rat
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    Congenit Anom (Kyoto) 51:174-6. 2011
    ..We suggest that these changes in phospholipids in the diabetic placenta might be involved in development of fetal malformation in a type 1 diabetic pregnancy...
  10. ncbi request reprint Slit3 regulates cell motility through Rac/Cdc42 activation in lipopolysaccharide-stimulated macrophages
    Toshihiko Tanno
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    FEBS Lett 581:1022-6. 2007
    ..These results suggest that slit3 functions as an intracellular signaling molecule for cell motility as part of the LPS-induced signaling cascade...
  11. ncbi request reprint Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development
    Chisa Ichikawa
    Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano shi, Osaka, Japan
    Histol Histopathol 28:257-68. 2013
    ..A3 would become a useful antibody to know the kinetics of rat hair follicle-constituting cells...
  12. ncbi request reprint Urinary metabolic fingerprinting for thioacetamide-induced rat acute hepatic injury using fourier transform-ion cyclotron resonance mass spectrometry (FT-ICR MS), with reference to detection of potential biomarkers for hepatotoxicity
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmenal Science, Osaka Prefecture University, Sakai, Osaka, Japan
    Toxicol Pathol 35:570-5. 2007
    ..dCty might be a biomarker for the acute hepatotoxicity in rats...
  13. pmc Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds
    Tsutomu Shimada
    Laboratory of Cellular and Molecular Biology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1 58 Rinku Orai Kita, Izumisano, Osaka 598 8531, Japan
    Chem Res Toxicol 24:1327-37. 2011
    ....
  14. ncbi request reprint Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Exp Toxicol Pathol 59:115-20. 2007
    ..These results indicate that PAG, IDN and HA are biomarkers for AMD-induced PLD in urinary metabolic fingerprinting using FT-ICR MS. These markers may be useful for evaluation of chemicals, which have the potential to induce PLD...
  15. ncbi request reprint Expression of a chemorepellent factor, Slit2, in peripheral nerve regeneration
    Toshihiko Tanno
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    Biosci Biotechnol Biochem 69:2431-4. 2005
    ..These results suggest that disruption of the continuity of basal lamina tubes induces the expression of slit2 in Schwann cells during peripheral nerve regeneration...
  16. doi request reprint Cellular responses in the spinal cord during development of hypomyelination in the mv rat
    Takeshi Izawa
    Department of Veterinary Sciences, Osaka Prefecture University, Gakuencho 1 1, Nakaku, Sakai, Osaka 599 8531, Japan
    Brain Res 1195:120-9. 2008
    ..The data suggest that attractin may be directly involved in the function of oligodendrocytes in CNS myelination...
  17. doi request reprint Metabolic fingerprinting of amniotic fluid from the streptozotocin-induced diabetic pregnant rat using Fourier transform-ion cyclotron resonance mass spectrometry
    Mina Hasegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
    Congenit Anom (Kyoto) 48:137-9. 2008
    ..The alteration of biochemical composition in the diabetic amniotic fluid suggests the presence of potential biomarkers to indicate progression of malformation under the diabetic pregnancy...
  18. doi request reprint Detection of chromogranin A in the adrenal gland extracts of different animal species by an enzyme-linked immunosorbent assay using Thomsen-Friedenreich antigen-specific Amaranthus caudatus lectin
    Hideo Akiyoshi
    Laboratory of Veterinary Surgery, Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan
    Vet Immunol Immunopathol 144:255-8. 2011
    ..Thus, ACA is concluded to be a valuable reagent for CgA detection in crude extracts from different animal species, and for CgA isolation/purification...
  19. ncbi request reprint Expression and function of Slit1alpha, a novel alternative splicing product for slit1
    Toshihiko Tanno
    Department of Veterinary Science, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    J Biochem 136:575-81. 2004
    ..These findings suggest that Slit1alpha is an active Slit1 protein specific in the vertebrate nervous system...
  20. pmc Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study
    Tsutomu Shimada
    Laboratory of Cellular and Molecular Biology, Department of Veterinary Science, Osaka Prefecture University, 1 58 Rinku Orai Kita, Izumisano, Osaka 598 8531, USA
    Chem Res Toxicol 22:1325-33. 2009
    ..Substitutions on the compounds with various acetylenic groups and propargyl ethers cause an increase or decrease of their affinities to P450 1B1, depending on the parent compound used...
  21. ncbi request reprint Hypoxia-induced megaloblastosis in vitamin B12-deficient rats
    Shuhei Ebara
    Department of Applied Biological Chemistry, Osaka Prefecture University, Sakai, Osaka, Japan
    Br J Nutr 89:441-4. 2003
    ..These results indicate that a megaloblastic anaemia-like symptom is induced when the vitamin B12-deficient rats are exposed to hypoxia...
  22. ncbi request reprint Adipogenic, osteogenic and myofibrogenic differentiations of a rat malignant fibrous histiocytoma (MFH)-derived cell line, and a relationship of MFH cells with embryonal mesenchymal, perivascular and bone marrow stem cells
    Jyoji Yamate
    Laboratory of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Gakuencho 1 1, Sakai, Osaka 599 8531, Japan
    Eur J Cancer 43:2747-56. 2007
    ..c-kit mRNA expression was seen in bone marrows and MT-9. Collectively, progenitors of MFH should be sought in lineage of marrow stem cells capable of differentiating into mesenchymal cells...
  23. ncbi request reprint Nitric oxide synthase induction, cGMP elevation, and biopterin synthesis in vascular smooth muscle cells stimulated with interleukin-1beta in hypoxia
    Kaori Nagao
    Department of Applied Biological Chemistry, Osaka Prefecture University, Sakai, Osaka 599 8531
    J Biochem 133:501-5. 2003
    ..In addition, the IL-1beta-induced synthesis of tetrahydrobiopterin, a cofactor for iNOS, was also greatly stimulated by hypoxia in VSMC...
  24. pmc Gas chromatography-mass spectrometry-based metabolic profiling of cerebrospinal fluid from epileptic dogs
    Tetsuya Hasegawa
    Department of Veterinary Science, Graduated School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka 598 8531, Japan
    J Vet Med Sci 76:517-22. 2014
    ..These findings show that metabolic profiles of CSF differ between idiopathic and symptomatic epilepsy and that metabolites including glutamic acid and ascorbic acid in CSF may be useful for diagnosis of canine epilepsy. ..
  25. ncbi request reprint Amelioration of the progression of an atopic dermatitis-like skin lesion by silk peptide and identification of functional peptides
    Yasuhira Ikegawa
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan
    Biosci Biotechnol Biochem 76:473-7. 2012
    ..Our findings indicate that silk peptide exerts an effect on atopic dermatitis by modulating the Th1/Th2 balance...
  26. ncbi request reprint Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes)
    Madoka Inui
    Department of Applied Biological Chemistry, Osaka Prefecture University, Osaka 599 8531, Japan
    Toxicology 194:43-50. 2003
    ..In this study, we showed that 4-MBC, OMC, and PP have estrogenic activity in fish...
  27. ncbi request reprint Identification and molecular characterization of mitochondrial ferredoxins and ferredoxin reductase from Arabidopsis
    Keiko Takubo
    Graduate School of Agriculture and Biosciences, Osaka Prefecture University, 1 1 Gakuen cho, Sakai 599 8531, Japan
    Plant Mol Biol 52:817-30. 2003
    ..Possible physiological roles of these mitochondrial electron transfer components are discussed in relation to redox dependent metabolic pathways in plants...
  28. pmc Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity
    Tsutomu Shimada
    Laboratory of Cellular and Molecular Biology, Department of Veterinary Science, Osaka Prefecture University, 1 1 Gakuen cho, Naka ku, Sakai, Osaka 599 8531, Japan
    Chem Res Toxicol 21:2313-23. 2008
    ....
  29. doi request reprint Production and characterization of a novel monoclonal antibody against Vibrio parahaemolyticus F0F1 ATP synthase's delta subunit and its application for rapid identification of the pathogen
    Junko Sakata
    Division of Bacteriology, Osaka Prefectural Institute of Public Health, 1 3 69, Nakamichi, Higashinari ku, Osaka 537 0025, Japan
    J Microbiol Methods 88:77-82. 2012
    ..parahaemolyticus colonies as compared with the conventional biochemical test...
  30. ncbi request reprint Mutation at the Lmx1a locus provokes aberrant brain development in the rat
    Mitsuru Kuwamura
    Laboratory of Veterinary Pathology, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Brain Res Dev Brain Res 155:99-106. 2005
    ..These findings suggest that the qc mutation is involved in development of the ventricular system and dorsal migration of neurons...
  31. ncbi request reprint Determination of unique amino acid substitutions in protein variants by peptide mass mapping with FT-ICR MS
    Katsuhiro Tanaka
    Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan
    J Am Soc Mass Spectrom 17:508-13. 2006
    ..Therefore, FTICR MS is capable of identifying all 53 types of substitutions, each of which is associated with a unique mass difference, except for the Leu and Ile isomers...
  32. ncbi request reprint Pyruvate:NADP+ oxidoreductase is stabilized by its cofactor, thiamin pyrophosphate, in mitochondria of Euglena gracilis
    Masami Nakazawa
    Department of Applied Biological Chemistry, Osaka Prefecture University, Sakai, Osaka 599 8531, Japan
    Arch Biochem Biophys 411:183-8. 2003
    ..These findings suggest that PNO is readily degraded when TPP is not provided in mitochondria, and consequently the PNO protein level is greatly reduced by thiamin deficiency in E. gracilis...
  33. ncbi request reprint Characterization and bioavailability of vitamin B12-compounds from edible algae
    Fumio Watanabe
    Department of Health Science, Kochi Women s University, Kochi 780 8515, Japan
    J Nutr Sci Vitaminol (Tokyo) 48:325-31. 2002
    ..Pseudovitamin B12 (an inactive corrinoid) predominated in the spirulina tablets, which are not suitable for use as a vitamin B12 source, especially for vegetarians. algal health food, bioavailability, cobalamin, edible algae, vitamin B12..