T Shoji

Summary

Affiliation: Osaka City University
Country: Japan

Publications

  1. ncbi request reprint Sodium sensitivity and sympathetic nervous system in hypertension induced by long-term nitric oxide blockade in rats
    S Yuasa
    Second Department of Internal Medicine, School of Medicine, Kagawa Medical University, Japan
    Clin Exp Pharmacol Physiol 27:18-24. 2000
  2. doi request reprint Influence of atherosclerosis on the relationship between anaemia and mortality risk in haemodialysis patients
    Kiyoshi Maekawa
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Nephrol Dial Transplant 23:2329-36. 2008
  3. ncbi request reprint Association of serum fetuin-A with carotid arterial stiffness
    Katsuhito Mori
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Endocrinol (Oxf) 66:246-50. 2007
  4. ncbi request reprint Regional arterial stiffness associated with ischemic heart disease in type 2 diabetes mellitus
    Sawako Hatsuda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Atheroscler Thromb 13:114-21. 2006
  5. ncbi request reprint Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients
    Eiji Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 45:859-65. 2005
  6. ncbi request reprint Serum lipids and prevention of atherosclerotic cardiovascular events in hemodialysis patients
    Tetsuo Shoji
    Department of Geriatrics and Vascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Exp Nephrol 18:257-60. 2014
  7. pmc Undercarboxylated osteocalcin does not correlate with insulin resistance as assessed by euglycemic hyperinsulinemic clamp technique in patients with type 2 diabetes mellitus
    Katsuhito Mori
    Deaprtment of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Diabetol Metab Syndr 4:53. 2012
  8. doi request reprint Serum n-3 and n-6 polyunsaturated fatty acid profile as an independent predictor of cardiovascular events in hemodialysis patients
    Tetsuo Shoji
    Department of Geriatrics and Vascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 62:568-76. 2013
  9. ncbi request reprint Thrice-weekly insulin injection with nurse's support for diabetic hemodialysis patients having difficulty with self injection
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 58:35-8. 2012
  10. doi request reprint Decreased serum adrenal androgen dehydroepiandrosterone sulfate and mortality in hemodialysis patients
    Ryusuke Kakiya
    Department of Metabolism, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephrol Dial Transplant 27:3915-22. 2012

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Sodium sensitivity and sympathetic nervous system in hypertension induced by long-term nitric oxide blockade in rats
    S Yuasa
    Second Department of Internal Medicine, School of Medicine, Kagawa Medical University, Japan
    Clin Exp Pharmacol Physiol 27:18-24. 2000
    ....
  2. doi request reprint Influence of atherosclerosis on the relationship between anaemia and mortality risk in haemodialysis patients
    Kiyoshi Maekawa
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Nephrol Dial Transplant 23:2329-36. 2008
    ..Since CKD is a high-risk population for cardiovascular disease (CVD), we tested a hypothesis that the presence of atherosclerosis affects the relationship between anaemia and mortality risk...
  3. ncbi request reprint Association of serum fetuin-A with carotid arterial stiffness
    Katsuhito Mori
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Endocrinol (Oxf) 66:246-50. 2007
    ..The objective of this study was to investigate the association between serum fetuin-A levels and arterial stiffness, a functional property of atherosclerosis, in healthy subjects...
  4. ncbi request reprint Regional arterial stiffness associated with ischemic heart disease in type 2 diabetes mellitus
    Sawako Hatsuda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Atheroscler Thromb 13:114-21. 2006
    ..Thus, diabetic patients with IHD have increased stiffness of arteries, particularly of the aorta, supporting the concept that central arterial stiffness plays an important role in the development of IHD...
  5. ncbi request reprint Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients
    Eiji Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 45:859-65. 2005
    ..Although an increased serum phosphate concentration is a significant risk factor for vascular calcification, it is unclear whether serum phosphate level is a risk factor for increased arterial wall thickness in hemodialysis patients...
  6. ncbi request reprint Serum lipids and prevention of atherosclerotic cardiovascular events in hemodialysis patients
    Tetsuo Shoji
    Department of Geriatrics and Vascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Exp Nephrol 18:257-60. 2014
    ..New directions of lipid research in CKD include cholesterol metabolism markers, omega-3 polyunsaturated fatty acids, and modifications of lipoproteins...
  7. pmc Undercarboxylated osteocalcin does not correlate with insulin resistance as assessed by euglycemic hyperinsulinemic clamp technique in patients with type 2 diabetes mellitus
    Katsuhito Mori
    Deaprtment of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Diabetol Metab Syndr 4:53. 2012
    ..abstract:..
  8. doi request reprint Serum n-3 and n-6 polyunsaturated fatty acid profile as an independent predictor of cardiovascular events in hemodialysis patients
    Tetsuo Shoji
    Department of Geriatrics and Vascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 62:568-76. 2013
    ..We examined possible alterations in serum PUFA profiles in patients on maintenance hemodialysis therapy and its association with CVD risk...
  9. ncbi request reprint Thrice-weekly insulin injection with nurse's support for diabetic hemodialysis patients having difficulty with self injection
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 58:35-8. 2012
    ..These preliminary results suggest that this regimen can be one of the practical choices in poor-controlled diabetes patients on regular hemodialysis who have difficulty in self injection of insulin...
  10. doi request reprint Decreased serum adrenal androgen dehydroepiandrosterone sulfate and mortality in hemodialysis patients
    Ryusuke Kakiya
    Department of Metabolism, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephrol Dial Transplant 27:3915-22. 2012
    ..The aims of this study were to examine a possible change in the DHEA-S level in dialysis patients and its association with survival in this population...
  11. ncbi request reprint Chronic kidney disease, dyslipidemia, and atherosclerosis
    Tetsuo Shoji
    Department of Geriatrics and Vascular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Osaka, Japan
    J Atheroscler Thromb 19:299-315. 2012
    ....
  12. pmc Serum C-reactive protein and thioredoxin levels in subjects with mildly reduced glomerular filtration rate
    Shoko Tsuchikura
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    BMC Nephrol 11:7. 2010
    ..We compared the levels of serum biomarkers for inflammation and oxidative stress between subjects with normal and mildly reduced glomerular filtration rate (GFR)...
  13. doi request reprint Plasma angiopoietin-like protein 3 (ANGPTL3) concentration is associated with uremic dyslipidemia
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    Atherosclerosis 207:579-84. 2009
    ..Since the role of angiopoietin-like protein 3 (ANGPTL3) in uremic dyslipidemia is unknown, we examined its possible association with the lipoprotein abnormalities in patients with chronic renal failure (CRF)...
  14. ncbi request reprint Advanced atherosclerosis in predialysis patients with chronic renal failure
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Kidney Int 61:2187-92. 2002
    ..The purpose of this study was to evaluate the effects of hemodialysis and renal failure on CA-IMT in patients with chronic renal failure...
  15. doi request reprint Small dense low-density lipoprotein cholesterol concentration and carotid atherosclerosis
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Atherosclerosis 202:582-8. 2009
    ....
  16. ncbi request reprint Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease
    T Shoji
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Am Soc Nephrol 12:2117-24. 2001
    ..These results demonstrate that the increased aortic stiffness of the ESRD patients with diabetes mellitus contributed to the higher all-cause and cardiovascular mortality rates...
  17. ncbi request reprint Body fat measurement in chronic kidney disease: implications in research and clinical practice
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    Curr Opin Nephrol Hypertens 16:572-6. 2007
    ..The purpose of this review is to update the concept on body fat in patients with chronic kidney disease...
  18. ncbi request reprint Plasma lipoprotein abnormalities in hemodialysis patients--clinical implications and therapeutic guidelines
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Ther Apher Dial 10:305-15. 2006
    ..For severe hypercholesterolemia, LDL-apheresis is another choice for consideration. Further studies are needed to clearly prove the benefit of lipid reduction in hemodialysis patients and those with CKD at earlier stages...
  19. ncbi request reprint Altered relationship between body fat and plasma adiponectin in end-stage renal disease
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Metabolism 54:330-4. 2005
    ..Thus, plasma adipocytokine profile was altered in ESRD, and the effects of body fat and sex on adiponectin were less significant in the patients with ESRD...
  20. ncbi request reprint Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Nephrol Dial Transplant 19:179-84. 2004
    ..We hypothesized that treatment with vitamin D(3) may be beneficial for survival in patients with end-stage renal disease (ESRD)...
  21. doi request reprint Arterial stiffness predicts cardiovascular death independent of arterial thickness in a cohort of hemodialysis patients
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Ashahi machi, Abeno Ku, Osaka 545 8585, Japan
    Atherosclerosis 210:145-9. 2010
    ..Although these arterial changes develop in parallel, no study has ever tested a hypothesis that arterial stiffness can predict mortality from CVD independent of arterial thickness. This study tested this possibility...
  22. ncbi request reprint Atherogenic lipoproteins in end-stage renal disease
    T Shoji
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S30-3. 2001
    ..The effect of lipid-lowering therapy on cardiovascular mortality in ESRD, however, awaits the results of ongoing prospective trials...
  23. doi request reprint Central versus peripheral arterial stiffness in association with coronary, cerebral and peripheral arterial disease
    Shoko Tsuchikura
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Atherosclerosis 211:480-5. 2010
    ..We measured pulse wave velocity (PWV) in four arterial segments, and examined the relative changes in the four regional PWVs in patients with CAD, CVD or PAD...
  24. pmc Elevated non-high-density lipoprotein cholesterol (non-HDL-C) predicts atherosclerotic cardiovascular events in hemodialysis patients
    Tetsuo Shoji
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Clin J Am Soc Nephrol 6:1112-20. 2011
    ..We tested a hypothesis that dyslipidemia increases the risk of incident atherosclerotic CVD and that protein energy wasting (PEW) increases the risk of fatality after CVD events in hemodialysis patients...
  25. ncbi request reprint Atherogenic lipoprotein changes in diabetic nephropathy
    T Shoji
    Second Department of Internal Medicine, Osaka City University Medical School, 1 4 3 Asahi machi, Osaka 545 8585, Abeno Ku, Japan
    Atherosclerosis 156:425-33. 2001
    ..These lipoprotein alterations may contribute to an increased cardiovascular risk in diabetic nephropathy, especially in diabetic renal failure...
  26. doi request reprint Reverse epidemiology in hemodialysis patients. Lessons from Japanese registries
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephrol Ther 4:223-7. 2008
  27. ncbi request reprint Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects
    T Shoji
    Second Department of Internal Medicine, Osaka City University Medical School, 1 4 3, Asahi machi, Abeno Ku, Osaka, Japan
    Atherosclerosis 148:171-7. 2000
    ..Although these results suggest that oxLDL Ab may play a role in maintaining the low level of plasma oxLDL, its role in atherogenesis awaits further studies...
  28. ncbi request reprint Impact of insulin resistance and nephropathy on homocysteine in type 2 diabetes
    M Emoto
    Second Department of Internal Medicine, Institute of Geriatrics and Medical Science, Osaka City University Medical School, Japan
    Diabetes Care 24:533-8. 2001
    ..To assess the impacts of insulin resistance and renal function on plasma total homocysteine (tHcy) levels in patients with type 2 diabetes with a wide range of nephropathy...
  29. ncbi request reprint Glycemic control is a predictor of survival for diabetic patients on hemodialysis
    T Morioka
    Department of Internal Medicine, Osaka City University Graduate Medical School, Osaka, Japan
    Diabetes Care 24:909-13. 2001
    ..133 per 1.0% increment of HbA1c, 95% CI 1.028-1.249, P = 0.012), as were Cre and CTR. CONCLUSIONS: Good glycemic control (HbA1c <7.5%) predicts better survival of diabetic ESRD patients starting hemodialysis treatment...
  30. ncbi request reprint Renal insufficiency accelerates atherosclerosis in patients with type 2 diabetes mellitus
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S186-90. 2001
    ....
  31. ncbi request reprint Arterial wall stiffness is associated with peripheral circulation in patients with type 2 diabetes
    Akane Kizu
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Atherosclerosis 170:87-91. 2003
    ..Thus, arterial wall stiffness of femoral artery appears to be a major determinant of peripheral circulation in patients with type 2 diabetes...
  32. ncbi request reprint Plasma leptin level and its relationship with body composition in hemodialysis patients
    Y Nishizawa
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 31:655-61. 1998
    ....
  33. ncbi request reprint Paradox of risk factors for cardiovascular mortality in uremia: is a higher cholesterol level better for atherosclerosis in uremia?
    Y Nishizawa
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S4-7. 2001
    ..Further studies are needed to show the differential effects of a risk factor on event rate and fatality rate. Patients with ESRD would have a better chance of living longer by better management of the two categories of risk factors...
  34. ncbi request reprint Femoral artery wall thickness and stiffness in evaluation of peripheral vascular disease in type 2 diabetes mellitus
    H Taniwaki
    Second Department of Internal Medicine, Osaka City University Medical School, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan
    Atherosclerosis 158:207-14. 2001
    ..These data suggest that stiffening of arterial wall has a significant impact on PVD manifestations, particularly on the leg symptoms, in patients with type 2 diabetes...
  35. ncbi request reprint Short-term aerobic exercise improves arterial stiffness in type 2 diabetes
    Hisayo Yokoyama
    Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetes Res Clin Pract 65:85-93. 2004
    ..To investigate whether: (1) aerobic exercise decreases arterial stiffness and (2) reduction in arterial stiffness is associated with improvement in insulin resistance in type 2 diabetes...
  36. ncbi request reprint Different risk factors for peripheral vascular calcification between diabetic and non-diabetic haemodialysis patients--importance of glycaemic control
    E Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetologia 45:1446-8. 2002
    ..We compared factors affecting peripheral vascular calcification between haemodialysis patients with and without diabetes...
  37. ncbi request reprint Increasing body fat mass in the first year of hemodialysis
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan Shirasagi Hospital Kidney Center, Osaka, Japan
    J Am Soc Nephrol 12:1921-6. 2001
    ..More general, dual x-ray absorptiometry assessment of body fat mass was found to be useful for evaluating the nutritional status of hemodialysis patients...
  38. ncbi request reprint Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients
    Koka Motoyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Metabolism 52:895-9. 2003
    ..In conclusion, the M416V polymorphism of GYS1 gene is not associated with insulin resistance in type 2 diabetes...
  39. ncbi request reprint Association between plasma angiopoietin-like protein 3 and arterial wall thickness in healthy subjects
    Sawako Hatsuda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Vasc Res 44:61-6. 2007
    ..We evaluated the possible association between plasma ANGPTL3 level and carotid artery intima-media thickness (CA-IMT) and femoral artery intima-media thickness (FA-IMT) in healthy human subjects...
  40. ncbi request reprint Arterial wall thickness is associated with insulin resistance in type 2 diabetic patients
    Shigehiko Fujiwara
    Metabolism, Endocrinology and Molecular Medicine, Department of Internal Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Atheroscler Thromb 10:246-52. 2003
    ..0001, respectively). In conclusion, insulin resistance is associated with both CA-IMT and FA-IMT in type 2 diabetic patients, suggesting that it is an independent risk factor for the development of atherosclerosis in type 2 diabetes...
  41. ncbi request reprint Significance of intima-media thickness in femoral artery in the determination of calcaneus osteo-sono index but not of lumbar spine bone mass in healthy Japanese people
    Shinsuke Yamada
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585, Osaka, Japan
    Osteoporos Int 16:64-70. 2005
    ....
  42. ncbi request reprint [Effects of vitamin D on the cardiovascular system]
    Tetsuo Shoji
    Osaka City University Graduate School of Medicine, Depanartment of Metabolism, Endocrinology and Molecular Medicine
    Clin Calcium 16:1107-14. 2006
    ..Experimentally, active vitamin D inhibits atherogenic cellular behaviors and activation of the renin-angiotensin system. Thus, active vitamin D is a regulator of cardiovascular and kidney functions...
  43. ncbi request reprint Effect of histamine H2-receptor antagonist on the phosphorus-binding abilities of calcium carbonate and calcium lactate in hemodialysis patients
    N Takahashi
    Second Department of Internal Medicine, Kagawa Medical University, Japan
    J Am Soc Nephrol 10:1090-4. 1999
    ..Calcium lactate may be useful as a phosphorus binder in such hemodialysis patients...
  44. ncbi request reprint Effects of lipid-lowering drugs on intermediate-density lipoprotein in uremic patients
    Y Nishizawa
    Osaka City University Medical School, Japan
    Kidney Int Suppl 71:S134-6. 1999
    ..There are a limited number of studies reporting pharmacological approaches to IDL reduction in a uremic population...
  45. ncbi request reprint The K469E polymorphism of the intercellular adhesion molecule-1 gene is associated with plasma fibrinogen level in type 2 diabetes
    Hisayo Yokoyama
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Metabolism 54:381-6. 2005
    ....
  46. ncbi request reprint Effect of diabetes on uremic dyslipidemia
    Eiji Kimoto
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Atheroscler Thromb 9:305-13. 2002
    ..These results indicate that increased IDL in ESRD is further deteriorated in the presence of diabetes, and that the adverse effect is accounted for at least partly by hypertriglyceridemia associated with chronic hyperglycemia...
  47. ncbi request reprint Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis
    Yasuro Kumeda
    Division of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Arthritis Rheum 46:1489-97. 2002
    ....
  48. ncbi request reprint Factors affecting progression of renal failure in patients with type 2 diabetes
    Hideki Ueda
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Diabetes Care 26:1530-4. 2003
    ..Hyperglycemia and hypertension are known to be risk factors for the development of proteinuria in patients with diabetes. Little is known, however, about predictors of progression of renal failure in diabetic patients...
  49. ncbi request reprint Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment in normal range weight and moderately obese type 2 diabetic patients
    Hisayo Yokoyama
    Osaka City University Graduate School of Medicine, Metabolism, Endocrinology and Molecular Medicine, Osaka, Japan
    Diabetes Care 26:2426-32. 2003
    ....
  50. doi request reprint Cerebral microbleeds in predialysis patients with chronic kidney disease
    Hideaki Shima
    Department of Endocrinology, Metabolism and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephrol Dial Transplant 25:1554-9. 2010
    ..Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease. The relationship between CKD and CMBs, which has not been clarified to date, is examined...
  51. doi request reprint Fetuin-A and atherosclerotic calcified plaque in patients with type 2 diabetes mellitus
    Masanori Emoto
    The Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Metabolism 59:873-8. 2010
    ..753; 95% confidence interval, 0.608-0.933; P = .010). These results suggest that fetuin-A may inhibit the calcification of atherosclerotic plaques independently of the dialyzed condition...
  52. doi request reprint Poor glycemic control is a significant predictor of cardiovascular events in chronic hemodialysis patients with diabetes
    Yoshihiro Tsujimoto
    Inoue Hospital, Osaka, Japan
    Ther Apher Dial 13:358-65. 2009
    ..0046, respectively). In diabetic hemodialysis patients, poor glycemic control is a significant, independent predictor of the emergence of CVD, indicating the importance of careful management of glycemic control in hemodialysis patients...
  53. ncbi request reprint Arterial stiffness in predialysis patients with uremia
    Kayo Shinohara
    Department of Metabolism, Osaka City University Graduate School of Medicine, Osaka, Japan
    Kidney Int 65:936-43. 2004
    ..We compared aortic PWV of uremic patients before starting hemodialysis treatment with that of patients on maintenance hemodialysis...
  54. ncbi request reprint [Vitamin D and survival of hemodialysis patients]
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
    Clin Calcium 14:64-8. 2004
    ..Although these observations need further confirmation by randomized controlled studies, appropriate use of active forms of vitamin D may improve the outcomes of patients with chronic kidney disease...
  55. ncbi request reprint Risk stratification based on metabolic syndrome as well as non- metabolic risk factors in the assessment of carotid atherosclerosis
    Hiroyuki Noda
    Public Health, Department of Social and Environmental Medicine, Osaka University, Graduate School of Medicine, Japan
    J Atheroscler Thromb 18:504-12. 2011
    ..We aimed to develop a new approach to risk stratification using metabolic syndrome as well as traditional non-metabolic risk factors, and to examine its validity in carotid atherosclerosis...
  56. ncbi request reprint Factors associated with silent cerebral microbleeds in hemodialysis patients
    T Naganuma
    Department of Urology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Nephrol 75:346-55. 2011
    ..The present study investigated the clinical factors associated with the presence of CMBs in hemodialysis (HD) patients...
  57. ncbi request reprint Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population
    A Yamada
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Metabolism 50:805-11. 2001
    ..These results suggest that insulin resistance or hyperinsulinemia is a factor contributing to the intragenotype variability of paraoxonase activity in a population without overt hyperglycemia...
  58. doi request reprint [Chronic kidney disease (CKD) and bone. Pleiotropic actions of vitamin D and survival advantage]
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University, Graduate School of Medicine
    Clin Calcium 19:514-21. 2009
    ..Furthermore, the use of active vitamin D is associated with decreased proteinuria and a lower risk for developing end-stage renal disease. Further evidence is needed to establish these pleiotropic actions of vitamin D...
  59. ncbi request reprint Regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease
    Eiji Kimoto
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Am Soc Nephrol 17:2245-52. 2006
    ..The cross-sectional result may explain the increased risk for cardiovascular disease in CKD, although longitudinal studies are needed to confirm it...
  60. ncbi request reprint Inflammation and bone resorption as independent factors of accelerated arterial wall thickening in patients with rheumatoid arthritis
    Mayumi Nagata-Sakurai
    Osaka City University Graduate School of Medicine, Osaka, Japan
    Arthritis Rheum 48:3061-7. 2003
    ..The present longitudinal study was performed to determine whether the change in arterial thickness was accelerated in RA patients and to determine which factor was important in the progression of arterial wall changes...
  61. ncbi request reprint The association of plasma adiponectin level with carotid arterial stiffness
    Takahiro Araki
    Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Metabolism 55:587-92. 2006
    ....
  62. ncbi request reprint Pulse wave velocity in lower-limb arteries among diabetic patients with peripheral arterial disease
    Hisayo Yokoyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Atheroscler Thromb 10:253-8. 2003
    ..The purpose of this study was to examine the possible alteration in pulse wave velocity (PWV) in lower-limb arteries among diabetic patients with PAD...
  63. ncbi request reprint Aortic calcification in haemodialysis patients with diabetes mellitus
    Hiromichi Taniwaki
    Inoue Hospital, Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Nephrol Dial Transplant 20:2472-8. 2005
    ..This study examined the risk factors of aortic calcification in a large number of haemodialysis patients, and compared risk factors between diabetic and non-diabetic patients...
  64. ncbi request reprint Roles of metabolic and endocrinological alterations in atherosclerosis and cardiovascular disease in renal failure: another form of metabolic syndrome
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Medical School, Osaka, Japan
    Semin Nephrol 24:423-5. 2004
    ..It is expected that treatment of these metabolic and endocrinologic alterations would improve the survival of patients with renal failure...
  65. doi request reprint Glimepiride increases high-density lipoprotein cholesterol via increasing adiponectin levels in type 2 diabetes mellitus
    Takahiro Araki
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Metabolism 58:143-8. 2009
    ..524, P = .036). In conclusion, glimepiride improved plasma adiponectin level, especially in the subjects with type 2 diabetes mellitus with low adiponectin level before treatment, and may directly contribute to improving HDL-c level...
  66. ncbi request reprint Platelet P-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans
    Hidenori Koyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Circulation 108:524-9. 2003
    ..In the present study, we examine the relation between platelet P-selectin expression and atherosclerotic parameters in 517 subjects...
  67. doi request reprint Effects of pravastatin on serum osteoprotegerin levels in patients with hypercholesterolemia and type 2 diabetes
    Katsuhito Mori
    Departments of Metabolism, Endocrinology, and Molecular Medicinev Osaka City University Graduate School of Medicine, Osaka, Japan
    Angiology 61:86-91. 2010
    ..05 +/- 2.22 pmol/L, P = .026). These findings suggest that pravastatin may exert its pleiotropic effects in part through alteration of osteoprotegerin levels...
  68. doi request reprint Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus
    Katsuhito Mori
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Metabolism 57:1248-52. 2008
    ..9 microg/mL, P = .006), whereas there were no changes in serum fetuin-A after intervention in either the Met or the Ex groups. We hypothesize that pioglitazone could partially ameliorate insulin resistance via modulating fetuin-A levels...
  69. ncbi request reprint Insulin resistance as an independent predictor of cardiovascular mortality in patients with end-stage renal disease
    Kayo Shinohara
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Am Soc Nephrol 13:1894-900. 2002
    ..In contrast, HOMA-IR did not show such a significant association with noncardiovascular mortality. These results indicate that insulin resistance is an independent predictor of cardiovascular mortality in ESRD...
  70. ncbi request reprint Preferential stiffening of central over peripheral arteries in type 2 diabetes
    Eiji Kimoto
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Diabetes 52:448-52. 2003
    ..In contrast, sex was associated with PWV of the peripheral arteries. Thus, type 2 diabetes had greater impact on PWV of the central arteries, and different factors were involved in PWV among different arterial regions...
  71. ncbi request reprint C-reactive protein is a significant predictor of vascular calcification of both aorta and hand arteries
    Eiji Ishimura
    Osaka City University Graduate School of Medicine, Osaka, Japan
    Semin Nephrol 24:408-12. 2004
    ....
  72. ncbi request reprint Body fat mass in hemodialysis patients
    Eiji Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine and Shirasagi Hospital Kidney Center, Osaka, Japan
    Am J Kidney Dis 41:S137-41. 2003
    ..Changes in body fat mass in a large number of hemodialysis patients is unknown...
  73. ncbi request reprint Effect of aerobic exercise on plasma adiponectin levels and insulin resistance in type 2 diabetes
    Hisayo Yokoyama
    Department of Metabolism, Osaka City University Graduate School of Medicine, Osaka, Japan
    Diabetes Care 27:1756-8. 2004
  74. ncbi request reprint Chronic kidney disease as a metabolic syndrome with malnutrition--need for strict control of risk factors
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka 545 8585
    Intern Med 44:179-87. 2005
    ..In this article, we review the unique situation of CKD, emphasizing the need of more strict control of both types of risk factors to improve survival of CKD patients...
  75. ncbi request reprint FGF-23 in patients with end-stage renal disease on hemodialysis
    Yasuo Imanishi
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Kidney Int 65:1943-6. 2004
    ..Although the mechanism of regulation of FGF-23 secretion is unknown, plasma FGF-23 level may be regulated or affected by serum phosphate levels because of its hypophosphatemic effect...
  76. ncbi request reprint Clinical impact of metabolic syndrome by modified NCEP-ATPIII criteria on carotid atherosclerosis in Japanese adults
    Megumi Teramura
    Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Atheroscler Thromb 14:172-8. 2007
    ....
  77. doi request reprint Fetuin-A is associated with calcified coronary artery disease
    Katsuhito Mori
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    Coron Artery Dis 21:281-5. 2010
    ..As diabetes and uremia make the role of fetuin-A in cardiovascular disease uncertain, we investigated the association between fetuin-A and calcified coronary artery disease in participants without diabetes and renal dysfunction...
  78. ncbi request reprint Decreased plasma adiponectin levels in young obese males
    Taketaka Hara
    Department of Sports Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan
    J Atheroscler Thromb 10:234-8. 2003
    ..406, p < 0.05). These results show that obesity is associated with reduced plasma adiponectin even in young subjects...
  79. ncbi request reprint Intima-media thickness of carotid artery predicts cardiovascular mortality in hemodialysis patients
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Am J Kidney Dis 41:S76-9. 2003
    ..Previous studies showed that patients with ESRD had increased intima-media thickness of the carotid artery (CA-IMT). In the present study, we examined whether CA-IMT would predict cardiovascular mortality in patients with ESRD...
  80. ncbi request reprint Antibody to oxidized low-density lipoprotein and cardiovascular mortality in end-stage renal disease
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Kidney Int 62:2230-7. 2002
    ..Immune response to oxidized low-density lipoprotein (oxLDL) may modulate the process of atherogenesis and cardiovascular disease...
  81. ncbi request reprint Different risk factors for vascular calcification in end-stage renal disease between diabetics and nondiabetics: the respective importance of glycemic and phosphate control
    Eiji Ishimura
    Osaka City University Graduate School of Medicine, Osaka, Japan
    Kidney Blood Press Res 31:10-5. 2008
    ..Thus, the importance of glycemic and phosphate control is suggested to be emphasized in diabetic and nondiabetic ESRD patients, respectively, for prevention of the progression of vascular calcification...
  82. ncbi request reprint Insulin resistance index as a predictor for pioglitazone treatment in type 2 diabetes
    Takahiro Araki
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Osaka City Med J 51:19-25. 2005
    ..The purpose of the present study was to investigate whether insulin resistance index, homeostasis model assessment index (HOMA-IR) is a useful predictor of hypoglycemic effect of pioglitazone in comparison with body mass index (BMI)...
  83. ncbi request reprint Plasma adiponectin level is associated with insulin-stimulated nonoxidative glucose disposal
    Hisayo Yokoyama
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    J Clin Endocrinol Metab 91:290-4. 2006
    ..Impaired nonoxidative glucose disposal and decrease in mitochondrial glucose oxidation both contribute to insulin resistance in diabetic subjects...
  84. ncbi request reprint Impact of glycemic control on survival of diabetic patients on chronic regular hemodialysis: a 7-year observational study
    Takeshi Oomichi
    Division of Metabolism, Endocrinology, and Molecular Medicine, Department of Internal Medicine, Osaka City University Graduate Medical School, 1 4 3, Asahi machi, Osaka, Japan 545 8585
    Diabetes Care 29:1496-500. 2006
    ..To investigate the impact of glycemic control during regular hemodialysis on the survival of diabetic patients with chronic kidney disease (CKD) in a longitudinal observational study...
  85. ncbi request reprint Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis
    Hidenori Koyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Arterioscler Thromb Vasc Biol 25:2587-93. 2005
    ..Here, we measured plasma esRAGE level with a recently developed enzyme-linked immunosorbent assay (ELISA) and examined its association with atherosclerosis in age- and gender-matched 203 type 2 diabetic and 134 nondiabetic subjects...
  86. ncbi request reprint Effect of adiponectin on carotid arterial stiffness in type 2 diabetic patients treated with pioglitazone and metformin
    Takahiro Araki
    Metabolism, Endocrinology, and Molecular Medicine, Department of Internal Medicine, Osaka City University Graduate Medical School, Osaka 545 8585, Japan
    Metabolism 55:996-1001. 2006
    ....
  87. ncbi request reprint Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease
    Hidenori Koyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Arterioscler Thromb Vasc Biol 27:147-53. 2007
    ..Here, we evaluated if plasma esRAGE is a predictor of cardiovascular mortality in a cohort of 206 (171 nondiabetic) patients with end-stage renal diseases (ESRD)...
  88. ncbi request reprint Urinary albumin excretion associated with arterial wall stiffness rather than thickness in type 2 diabetic patients
    Eiji Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Nephrol 20:204-11. 2007
    ..The aim of this study was to determine which of the 2 aspects of atherosclerosis, arterial thickening or stiffness, has more effect on levels of microalbuminuria in type 2 diabetic patients...
  89. ncbi request reprint Impact of Prol2Ala variant in the peroxisome proliferator-activated receptor (PPAR) gamma2 on obesity and insulin resistance in Japanese Type 2 diabetic and healthy subjects
    Isao Kawasaki
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Osaka City Med J 48:23-8. 2002
    ..These data suggest that the Pro12Ala polymorphism of PPAR gamma2 does not influence insulin resistance but body composition in Japanese diabetic subjects...
  90. doi request reprint Less maintenance immunosuppression in lung transplantation following hematopoietic stem cell transplantation from the same living donor
    F Chen
    Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Am J Transplant 11:1509-16. 2011
    ..In our study, LDLLT involving the same donor as for HSCT appeared to have advantages related to lower immunosuppression compared to LDLLT from relatives who were not the HSCT donors...
  91. doi request reprint Significance of tumor recurrence before pulmonary metastasis in pulmonary metastasectomy for soft tissue sarcoma
    F Chen
    Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    Eur J Surg Oncol 35:660-5. 2009
    ..To find an entity of patients benefiting from pulmonary metastasectomy, we reviewed our institutional experience...
  92. ncbi request reprint Statistical analysis of diagnostic failure of fine needle aspiration cytology (FNAC) in breast cancer
    K Tanaka
    Department of Surgery, Kansai Medical University, Osaka, Japan
    J Surg Oncol 76:100-5. 2001
    ..and intrinsic one (cellular factors of low atypism such as benign-like ultrasound finding, low tumor grade, and so on)...
  93. ncbi request reprint Body composition and cardiovascular risk in hemodialysis patients
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Ren Nutr 16:241-4. 2006
    ....
  94. ncbi request reprint Platelet activation is associated with hypoadiponectinemia and carotid atherosclerosis
    Takuhito Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    Atherosclerosis 188:190-5. 2006
    ..423), serum adiponectin levels (r = -0.289) and age (r = -0.184) were the three independent determinants. Thus, our data unveil novel link between hypoadiponectinemia and platelet activation...
  95. ncbi request reprint Atherosclerosis in renal failure
    Tetsuo Shoji
    Intern Med 42:1061-2. 2003
  96. ncbi request reprint Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment are useful indexes of insulin resistance in type 2 diabetic patients with wide range of fasting plasma glucose
    Hisayo Yokoyama
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545 8585, Japan
    J Clin Endocrinol Metab 89:1481-4. 2004
    ..730, respectively; all subjects, r = 0.685; all P < 0.001). In conclusion, QUICKI and the reciprocal index of HOMA were highly correlated with Clamp-IR in type 2 diabetic patients with relatively wide ranges of fasting plasma glucose...
  97. ncbi request reprint Increased arterial stiffening and thickening in the paretic lower limb in patients with hemiparesis
    Reiko Okabe
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Clin Sci (Lond) 106:613-8. 2004
    ....
  98. ncbi request reprint Smoking and proteinuria impair vasodilatory response of intrarenal arteries to nitroglycerine in patients with type 2 diabetes mellitus
    Naoki Matsumoto
    Second Department of Internal Medicine, Osaka City University Medical School, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Nephrol Dial Transplant 17:608-13. 2002
    ..Few studies have addressed the effect of vasodilatory stimuli on the intrarenal arterial system in type 2 diabetes mellitus (DM), and factors affecting its responsiveness...
  99. ncbi request reprint [Effects of parathyroid hormone gene polymorphism on cardiovascular mortality]
    Yoshihiro Tsujimoto
    Inoue Hospital
    Clin Calcium 15:106-9; discussion 109. 2005
    ....
  100. ncbi request reprint Does paricalcitol reduce proteinuria in patients with chronic kidney disease?
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nat Clin Pract Nephrol 2:352-3. 2006
  101. ncbi request reprint Impaired secretion of parathyroid hormone, but not refractoriness of osteoblast, is a major mechanism of low bone turnover in hemodialyzed patients with diabetes mellitus
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 39:1261-9. 2002
    ..In conclusion, our findings suggest that impaired PTH secretion, but not refractoriness of osteoblasts to PTH, may be responsible for the low bone turnover in hemodialyzed patients with diabetes...