Research Topics
Genomes and GenesSpecies | Nobuko MoriSummaryAffiliation: Osaka Prefecture University Country: Japan Publications
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Detail Information
Publications
Two loci controlling susceptibility to radiation-induced lymphomagenesis on mouse chromosome 4: cdkn2a, a candidate for one locus, and a novel locus distinct from cdkn2aNobuko Mori
Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1 2 Gakuen cho, Naka ku, Sakai shi, Osaka 599 8570, Japan
Radiat Res 173:158-64. 2010..Although Cdkn2a is a likely candidate for the locus controlling susceptibility to lymphomagenesis on chromosome 4, a novel tumor susceptibility gene different from Cdkn2a exists near the primary locus...
Ccdc85c encoding a protein at apical junctions of radial glia is disrupted in hemorrhagic hydrocephalus (hhy) miceNobuko Mori
Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Osaka, Japan
Am J Pathol 180:314-27. 2012..These findings indicate an important role of Ccdc85C in cortical development and provide a mouse model to study pathogenesis of subcortical heterotopia and hydrocephalus...
Distinct pattern of allelic loss and inactivation of cadherin 1 and 5 genes in mammary carcinomas arising in p53(+/-) miceSeiichi Umesako
Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Sakai, Japan
J Radiat Res 48:143-52. 2007..Thus, inactivation of Cdh1 and Cdh5 is likely to cooperate with the loss of p53, suggesting a possible tumor suppressive function of these genes in mammary carcinogenesis...
Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout miceSeiichi Umesako
Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Osaka, Japan
Breast Cancer Res 7:R164-70. 2005....
Allelic loss analysis of lymphomas induced in Fas-heterozygous deficient miceShoji Ogawa
Department of Veterinary Sciences, College of Agriculture, Osaka Prefecture University, 102 Gakuen cho, Sakai, Osaka 599 8570, Japan
J Vet Med Sci 66:97-102. 2004..Therefore, the putative tumor-suppressor gene regions responsible for lymphomagenesis might not considerably differ due to the Fas gene status...
Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12Mitsuru Kuwamura
Laboratory of Veterinary Pathology, Graduate School of Agriculture and Biological Sciences, Osaka, Japan
Brain Res Dev Brain Res 152:69-72. 2004..Subcortical heterotopia was detected unexceptionally in the mutants. Thus, the hhy mutation is characterized by three different abnormalities, i.e. hydrocephalus, intracranial hemorrhage and subcortical heterotopia...
Generation of large homozygous chromosomal segments by mitotic recombination during lymphomagenesis in F1 hybrid miceDoo-Pyo Hong
Research Institute for Advanced Science and Technology, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
J Radiat Res (Tokyo) 43:187-94. 2002..It is suggested that the generation of these large homozygous chromosomal segments probably containing the affected genes is one of the genetic alterations responsible for tumorigenesis...
Preferential induction of mammary tumors in p53 hemizygous BALB/c mice by fractionated irradiation of a sub-lethal dose of X-raysNobuko Mori
Research Institute for Advanced Science and Technology, Osaka Prefecture University, Osaka, Japan
J Radiat Res 44:249-54. 2003..Hence, we provided a useful experimental system to study radiation-induced mammary tumors in mice...
Putative tumor-suppressor gene regions responsible for radiation lymphomagenesis in F1 mice with different p53 statusDoo-Pyo Hong
Research Institute for Advanced Science and Technology, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, Sakai, Osaka, Japan
J Radiat Res (Tokyo) 43:175-85. 2002..Thus, the putative tumor-suppressor gene regions responsible for lymphomaganesis might considerably differ due to the p53 status...
