Sohkichi Mastumoto

Summary

Affiliation: Osaka City University
Country: Japan

Publications

  1. ncbi request reprint Extracellular mycobacterial DNA-binding protein 1 participates in mycobacterium-lung epithelial cell interaction through hyaluronic acid
    Keiko Aoki
    Department of Host Defense, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Biol Chem 279:39798-806. 2004
  2. pmc Development of avian influenza virus H5 DNA vaccine and MDP-1 gene of Mycobacterium bovis as genetic adjuvant
    Babak Jalilian
    Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia
    Genet Vaccines Ther 8:4. 2010
  3. pmc Growth inhibition of HeLa cell by internalization of Mycobacterium bovis Bacillus Calmette-Guérin (BCG) Tokyo
    Akira Kitamura
    Division of Oral and Maxillofacial Surgical Reconstruction and Functional Restoration, Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki 852 8588, Japan
    Cancer Cell Int 9:30. 2009
  4. ncbi request reprint DNA augments antigenicity of mycobacterial DNA-binding protein 1 and confers protection against Mycobacterium tuberculosis infection in mice
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Immunol 175:441-9. 2005
  5. pmc Mycobacteria exploit host hyaluronan for efficient extracellular replication
    Yukio Hirayama
    Department of Bacteriology, Osaka City University Graduate School of Medicine, Osaka, Osaka, Japan
    PLoS Pathog 5:e1000643. 2009
  6. ncbi request reprint Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium
    Hiroyuki Saiga
    Department of Microbiology and Immunology, Laboratory of Immune Regulation, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    J Immunol 181:8521-7. 2008
  7. doi request reprint Virulence of Mycobacterium avium complex strains isolated from immunocompetent patients
    Yoshitaka Tateishi
    Department of Bacteriology, Osaka City University Graduate School of Medicine, and Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka 560 8552, Japan
    Microb Pathog 46:6-12. 2009
  8. pmc Control of cell wall assembly by a histone-like protein in Mycobacteria
    Tomoya Katsube
    Department of Host Defense, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Bacteriol 189:8241-9. 2007
  9. ncbi request reprint [Molecular mechanisms of persistent infection and adherence/entry to host cells with Mycobacterium tuberculosis for the development of a novel therapeutic and prophylactic intervention]
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine, Japan
    Nihon Saikingaku Zasshi 61:345-52. 2006
  10. ncbi request reprint [Molecular mechanisms of persistent infection with mycobacterium tuberculosis and reactivation]
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine
    Nihon Rinsho 65:124-8. 2007

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Extracellular mycobacterial DNA-binding protein 1 participates in mycobacterium-lung epithelial cell interaction through hyaluronic acid
    Keiko Aoki
    Department of Host Defense, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Biol Chem 279:39798-806. 2004
    ..Taken together, theses results suggest that HA participates in Mycobacterium-lung epithelium interaction and has potential for therapeutic and prophylactic interventions in mycobacterial infection...
  2. pmc Development of avian influenza virus H5 DNA vaccine and MDP-1 gene of Mycobacterium bovis as genetic adjuvant
    Babak Jalilian
    Institute of Bioscience, University Putra Malaysia, Serdang 43400, Selangor, Malaysia
    Genet Vaccines Ther 8:4. 2010
    ..Vaccines are frequently formulated with adjuvants to improve their release, delivery and presentation to the host immune system...
  3. pmc Growth inhibition of HeLa cell by internalization of Mycobacterium bovis Bacillus Calmette-Guérin (BCG) Tokyo
    Akira Kitamura
    Division of Oral and Maxillofacial Surgical Reconstruction and Functional Restoration, Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki 852 8588, Japan
    Cancer Cell Int 9:30. 2009
    ..CONCLUSION: Proliferated Live BCG secreted the protein and depressed the growth of tumor. The possibility for clinical introduction of BCG therapy for carcinoma reported with review of literature...
  4. ncbi request reprint DNA augments antigenicity of mycobacterial DNA-binding protein 1 and confers protection against Mycobacterium tuberculosis infection in mice
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Immunol 175:441-9. 2005
    ..To our knowledge, MDP1 is the first protein discovered that remarkably augments the CpG-mediated immune response and is a potential adjuvant for CpG DNA-based immune therapies...
  5. pmc Mycobacteria exploit host hyaluronan for efficient extracellular replication
    Yukio Hirayama
    Department of Bacteriology, Osaka City University Graduate School of Medicine, Osaka, Osaka, Japan
    PLoS Pathog 5:e1000643. 2009
    ....
  6. ncbi request reprint Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium
    Hiroyuki Saiga
    Department of Microbiology and Immunology, Laboratory of Immune Regulation, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    J Immunol 181:8521-7. 2008
    ..Taken together, these findings highlight a pivotal role for alveolar epithelial cells during mycobacterial infection, in which Lcn2 mediates anti-mycobacterial innate immune responses within the epithelial cells...
  7. doi request reprint Virulence of Mycobacterium avium complex strains isolated from immunocompetent patients
    Yoshitaka Tateishi
    Department of Bacteriology, Osaka City University Graduate School of Medicine, and Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka 560 8552, Japan
    Microb Pathog 46:6-12. 2009
    ..The existence of such strain suggests the involvement of bacterial virulence in the pathogenesis of pulmonary MAC disease in immunocompetent status...
  8. pmc Control of cell wall assembly by a histone-like protein in Mycobacteria
    Tomoya Katsube
    Department of Host Defense, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Bacteriol 189:8241-9. 2007
    ..Our results demonstrate novel regulation of cell wall assembly which has an impact on bacterial growth...
  9. ncbi request reprint [Molecular mechanisms of persistent infection and adherence/entry to host cells with Mycobacterium tuberculosis for the development of a novel therapeutic and prophylactic intervention]
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine, Japan
    Nihon Saikingaku Zasshi 61:345-52. 2006
  10. ncbi request reprint [Molecular mechanisms of persistent infection with mycobacterium tuberculosis and reactivation]
    Sohkichi Matsumoto
    Department of Host Defense, Osaka City University Graduate School of Medicine
    Nihon Rinsho 65:124-8. 2007
  11. doi request reprint Transient role of CD4+CD25+ regulatory T cells in mycobacterial infection in mice
    Yuriko Ozeki
    Department of Bacteriology, Osaka City University Graduate School of Medicine, 1 4 3 Abeno ku, Osaka 545 8585, Japan
    Int Immunol 22:179-89. 2010
    ..tuberculosis. Our data show that CD4(+)CD25(+) Treg cells have a transient effect at the early stage of mycobacterial infection but, contrary to the expectation, have little impact on the overall course of infection...
  12. pmc A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction
    Masaki Takatsuka
    Department of Bacteriology, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    PLoS ONE 6:e20985. 2011
    ..This study describes for the first time a ferroxidase-iron storage protein outside of the ferritin superfamily proteins and the protective role of this bacterial protein from DNA damage...
  13. ncbi request reprint Mycobacterial trehalose 6,6'-dimycolate preferentially induces type 1 helper T cell responses through signal transducer and activator of transcription 4 protein
    Ryuta Oiso
    Department of Host Defense, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka 545 8585, Japan
    Microb Pathog 39:35-43. 2005
    ..These results shed light on the molecular pathogenesis of mycobacterial disease. Taken together with previous studies, TDM is a pleiotropic molecule against the host and participates in the pathogenesis...
  14. doi request reprint Loss of anti-mycobacterial efficacy in mice over time following vaccination with Mycobacterium bovis bacillus Calmette-Guérin
    Yuriko Ozeki
    Department of Bacteriology, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Vaccine 29:6881-7. 2011
    ..tuberculosis antigens. Our data suggest that the duration from vaccination may explain the variation in BCG efficacy against adult pulmonary tuberculosis...
  15. ncbi request reprint Mycobacterium avium complex organisms predominantly colonize in the bathtub inlets of patients' bathrooms
    Yukiko Nishiuchi
    Toneyama Institute for Tuberculosis Research Osaka City University Medical School, Osaka 560 8552, Japan
    Jpn J Infect Dis 62:182-6. 2009
    ....
  16. doi request reprint Mitochondrial density contributes to the immune response of macrophages to lipopolysaccharide via the MAPK pathway
    Emiko Kasahara
    Department of Biochemistry and Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno, Osaka, Japan
    FEBS Lett 585:2263-8. 2011
    ....
  17. pmc Structural analysis and biosynthesis gene cluster of an antigenic glycopeptidolipid from Mycobacterium intracellulare
    Nagatoshi Fujiwara
    Department of Host Defense, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Bacteriol 190:3613-21. 2008
    ..253 containing gtfB-drrC of M. intracellulare serotype 16, and the transformant produced serotype 16 GPL. Together, the ORFs of this serotype 16-specific gene cluster are responsible for the biosynthesis of serotype 16 GPL...
  18. ncbi request reprint Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor
    Junichi Nishimura
    Deparment of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    J Immunol 180:4032-9. 2008
    ..Mice lacking SLPI were highly susceptible to pulmonary infection with M. tuberculosis. Thus, mouse SLPI is an essential component of innate host defense against mycobacteria at the respiratory mucosal surface...
  19. ncbi request reprint Combined intrarectal/intradermal inoculation of recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces enhanced immune responses against the inserted HIV-1 V3 antigen
    Mamoru Kawahara
    AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Vaccine 21:158-66. 2002
    ..Thus, inoculation with rBCG-HIV by combined routes represents an effective vaccination strategy to elicit high levels of HIV-1-specific immune responses...
  20. pmc Priming-boosting vaccination with recombinant Mycobacterium bovis bacillus Calmette-Guérin and a nonreplicating vaccinia virus recombinant leads to long-lasting and effective immunity
    Yasushi Ami
    Division of Experimental Animal Research, National Institute of Infectious Diseases, Shinjuku ku, Tokyo, Japan
    J Virol 79:12871-9. 2005
    ..These results suggest that a recombinant M. bovis BCG-based vector may have potential as an HIV/AIDS vaccine when administered in combination with a replication-deficient vaccinia virus DIs vector in a priming-boosting strategy...
  21. pmc Mycobacterial codon optimization enhances antigen expression and virus-specific immune responses in recombinant Mycobacterium bovis bacille Calmette-Guérin expressing human immunodeficiency virus type 1 Gag
    Masaru Kanekiyo
    AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 79:8716-23. 2005
    ..01 mg of the codon-optimized rBCG per animal proved capable of eliciting immune responses, suggesting that even low doses of a codon-optimized rBCG-based vaccine could effectively elicit HIV-1-specific immune responses...
  22. ncbi request reprint Discovery of immunostimulatory CpG-DNA and its application to tuberculosis vaccine development
    Saburo Yamamoto
    National Institute of Infectious Diseases, Tokyo 208 0011, Japan
    Jpn J Infect Dis 55:37-44. 2002
    ..Therefore, CpG-DNA functions as an adjuvant for regulating the initiation of Th1 differentiation. The roles of immunostimulatory CpG motifs in DNA vaccine developments and in therapeutic applications have been discussed...