Shoji Kubo

Summary

Affiliation: Osaka City University
Country: Japan

Publications

  1. ncbi request reprint Case series of 17 patients with cholangiocarcinoma among young adult workers of a printing company in Japan
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    J Hepatobiliary Pancreat Sci 21:479-88. 2014
  2. pmc The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis
    Yoshiki Murakami
    Department of Hepatology, Graduate School of Medicine Osaka City University, Osaka 545 8585, Japan
    BMC Cancer 13:99. 2013
  3. ncbi request reprint Relationship between multicentric occurrence of hepatocellular carcinoma and histology of noncancerous hepatic tissue in patients with chronic hepatitis C
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Osaka
    Jpn J Cancer Res 90:1076-80. 1999
  4. ncbi request reprint Appropriate surgical management of small hepatocellular carcinomas in patients infected with hepatitis C virus
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    World J Surg 27:437-42. 2003
  5. ncbi request reprint Risk factors for massive blood loss during liver resection for hepatocellular carcinoma in patients with cirrhosis
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 54:830-3. 2007
  6. ncbi request reprint Effects of marker for hepatic fibrosis and viral status on recurrence after resection of hepatitis B virus-related hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:497-9. 2003
  7. ncbi request reprint Usefulness of biodegradable absorbable rib connecting pins in thoracoabdominal hepatectomy
    Shoji Kubo
    Second Department of Surgery, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:2141-2. 2003
  8. pmc Correlation between preoperative serum concentration of type IV collagen 7s domain and hepatic failure following resection of hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Ann Surg 239:186-93. 2004
  9. ncbi request reprint Polyamine metabolism and recurrence after resection for hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:208-10. 2004
  10. ncbi request reprint Detection of the draining vein from hepatic focal nodular hyperplasia on three-dimensional computed tomography
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:577-8. 2004

Collaborators

Detail Information

Publications81

  1. ncbi request reprint Case series of 17 patients with cholangiocarcinoma among young adult workers of a printing company in Japan
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    J Hepatobiliary Pancreat Sci 21:479-88. 2014
    ..An outbreak of cholangiocarcinoma occurred among workers in the offset color proof-printing department at a printing company in Japan. The aim of this study was to clarify the characteristics of the patients with cholangiocarcinoma...
  2. pmc The expression level of miR-18b in hepatocellular carcinoma is associated with the grade of malignancy and prognosis
    Yoshiki Murakami
    Department of Hepatology, Graduate School of Medicine Osaka City University, Osaka 545 8585, Japan
    BMC Cancer 13:99. 2013
    ..In hepatocellular carcinoma (HCC), malignancy level is related to the degree of histological differentiation...
  3. ncbi request reprint Relationship between multicentric occurrence of hepatocellular carcinoma and histology of noncancerous hepatic tissue in patients with chronic hepatitis C
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Osaka
    Jpn J Cancer Res 90:1076-80. 1999
    ..Measurement of platelet count, ALT activity, and the concentration of type 4 collagen, and histologic assessment of noncancerous hepatic tissue provide information useful for estimation of the potential for multicentric carcinogenesis...
  4. ncbi request reprint Appropriate surgical management of small hepatocellular carcinomas in patients infected with hepatitis C virus
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    World J Surg 27:437-42. 2003
    ..In patients with small HCV-related HCC, anatomic resection is recommended when the serum concentration of 7S collagen is low (< 8 ng/ml) because the potential of hepatocarcinogenesis may be low even after the operation...
  5. ncbi request reprint Risk factors for massive blood loss during liver resection for hepatocellular carcinoma in patients with cirrhosis
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 54:830-3. 2007
    ..We investigated risk factors for massive blood loss during liver resection and indications for storing blood for autologous intraoperative transfusion...
  6. ncbi request reprint Effects of marker for hepatic fibrosis and viral status on recurrence after resection of hepatitis B virus-related hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:497-9. 2003
    ....
  7. ncbi request reprint Usefulness of biodegradable absorbable rib connecting pins in thoracoabdominal hepatectomy
    Shoji Kubo
    Second Department of Surgery, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:2141-2. 2003
    ..The usefulness of absorbable rib connecting pins in thoracoabdominal hepatectomy was evaluated...
  8. pmc Correlation between preoperative serum concentration of type IV collagen 7s domain and hepatic failure following resection of hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Ann Surg 239:186-93. 2004
    ..To determine the predictive value of the preoperative serum concentration of type IV collagen 7s domain (7s collagen) for postoperative hepatic failure in patients undergoing liver resection for hepatocellular carcinoma...
  9. ncbi request reprint Polyamine metabolism and recurrence after resection for hepatocellular carcinoma
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:208-10. 2004
    ..We investigated the relationship between polyamine metabolism in hepatocellular carcinoma tissues and the recurrence after resection of hepatocellular carcinoma...
  10. ncbi request reprint Detection of the draining vein from hepatic focal nodular hyperplasia on three-dimensional computed tomography
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:577-8. 2004
    ..A draining vein connecting to the hepatic vein may be a characteristic of focal nodular hyperplasia. Three-dimensional computed tomography may be useful to diagnose focal nodular hyperplasia of the liver...
  11. doi request reprint Second hepatic resection for recurrent hepatocellular carcinoma in patients with chronic hepatitis C
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    World J Surg 32:632-8. 2008
    ..The risk factors for HCC recurrence after SHR were evaluated to investigate the indications for SHR...
  12. ncbi request reprint Evaluation of the effect of portal vein embolization on liver function by (99m)tc-galactosyl human serum albumin scintigraphy
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan
    J Surg Res 107:113-8. 2002
    ..Scintigraphy with (99m)Tc-galactosyl human serum albumin (GSA) causes specific binding to viable hepatocytes and serves as an index of liver function...
  13. ncbi request reprint Influence of previous interferon therapy on recurrence after resection of hepatitis c virus-related hepatocellular carcinoma
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Abeno Ku, Osaka 545 8585, Japan
    Jpn J Cancer Res 92:59-66. 2001
    ..336; 95%CI, 1.512 - 26.50). The patients with HCC who underwent IFN therapy previously are good candidates for liver resection because recurrence after the operation was rarely observed...
  14. ncbi request reprint Risk factors for recurrence after resection of hepatitis C virus-related hepatocellular carcinoma
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Japan
    World J Surg 24:1559-65. 2000
    ..For HCV-related HCCs, not only the degree of malignancy of the HCC but also HCV viremia and active hepatitis are risk factors for recurrence...
  15. ncbi request reprint Reconstruction of hepatic veins by anastomosis with suprahepatic IVC in the posterior mediastinum in living donor liver transplantation for Budd-Chiari syndrome
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan
    Hepatogastroenterology 56:1521-4. 2009
    ..The patient has been doing well, without any episode of thrombosis or occlusion of the graft hepatic veins at 1 year and 6 months after liver transplantation...
  16. ncbi request reprint Virologic and biochemical changes and prognosis after liver resection for hepatitis B virus-related hepatocellular carcinoma
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Osaka, Japan
    Dig Surg 18:26-33. 2001
    ..We investigated the effects of postoperative changes in virologic and biochemical parameters on the prognosis after liver resection for HBV-related hepatocellular carcinoma (HCC)...
  17. ncbi request reprint Randomized clinical trial of long-term outcome after resection of hepatitis C virus-related hepatocellular carcinoma by postoperative interferon therapy
    S Kubo
    Second Department of Surgery, Osaka City University Medical School, Osaka, Japan
    Br J Surg 89:418-22. 2002
    ..Effects of postoperative interferon therapy on the survival rate after resection of such HCC are still unclear...
  18. ncbi request reprint Clinicopathologic features and outcome after liver resection for hepatocellular carcinoma in patients with concurrent versus previous chronic hepatitis B
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Surg Today 35:216-22. 2005
    ..We compared the clinicopathologic features affecting outcome after surgery for hepatocellular carcinoma (HCC) between patients with concurrent and previous chronic hepatitis B...
  19. doi request reprint A simple, noninvasively determined index predicting hepatic failure following liver resection for hepatocellular carcinoma
    Tsuyoshi Ichikawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    J Hepatobiliary Pancreat Surg 16:42-8. 2009
    ..We evaluated the ability of preoperative APRI to predict hepatic failure following liver resection for hepatocellular carcinoma...
  20. ncbi request reprint Hepatectomy with transcatheter arterial embolization for large hepatoma in the caudate lobe
    Takatsugu Yamamoto
    Osaka City University Graduated School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:2173-5. 2003
    ..The combination of preoperative transcatheter arterial embolization and partial resection for caudate HCC, especially large solitary caudate HCC, works well as a multimodal therapy...
  21. ncbi request reprint Hepatitis B virus DNA integration in hepatocellular carcinoma after interferon-induced disappearance of hepatitis C virus
    Akihiro Tamori
    Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Gastroenterol 100:1748-53. 2005
    ..Hepatocellular carcinoma (HCC) has been reported in patients in whom hepatitis C virus (HCV) was eliminated by interferon (IFN) therapy. We examined the pathogenesis of HCC in patients with sustained viral response...
  22. doi request reprint Differences in molecular alterations of hepatocellular carcinoma between patients with a sustained virological response and those with hepatitis C virus infection
    Takehiro Hayashi
    Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Liver Int 29:126-32. 2009
    ..We compared molecular alterations in hepatocellular carcinoma (HCC) between patients with a sustained virological response (SVR) to IFN and patients with HCV...
  23. ncbi request reprint Two cases of intrahepatic cholangiocarcinoma detected after interferon therapy for chronic hepatitis C
    Akishige Kanazawa
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan
    Hepatogastroenterology 52:1869-73. 2005
    ..It is important to monitor carefully for ICC as well as hepatocellular carcinoma in patients with chronic hepatitis C, even when interferon therapy has been carried out, since the outcome of treatment for small ICC is favorable...
  24. ncbi request reprint Hepatocellular carcinoma (HCC) recurring 10 years after clearance of hepatitis B surface antigen and 20 years after resection of hepatitis B virus-related HCC
    Hiroji Shinkawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, 545 8585, Japan
    Int J Clin Oncol 13:562-6. 2008
    ..Cassette-ligation-mediated PCR showed that HBV DNA was integrated into the telomerase reverse transcriptase gene located on chromosome 5p15...
  25. ncbi request reprint Serum cytokeratin 19 fragment (CYFRA21-1) as a prognostic factor in intrahepatic cholangiocarcinoma
    Takahiro Uenishi
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Ann Surg Oncol 15:583-9. 2008
    ..This study aimed to establish the clinical significance of preoperative serum CYFRA21-1 in patients with intrahepatic cholangiocarcinoma...
  26. ncbi request reprint Type IV collagen 7s domain as a predictor of poor efficacy of portal vein embolization before major hepatectomy
    Jin Shang Wu
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Surg Today 35:41-6. 2005
    ..We investigated the correlation between serum concentrations of type IV collagen 7s domain (7s collagen) and changes in the volume of the nonembolized liver lobe after subsequent portal vein embolization (PVE)...
  27. ncbi request reprint Portal thrombosis due to intrahepatic cholangiocarcinoma following successful treatment for hepatocellular carcinoma
    Takahiro Uenishi
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 50:1140-2. 2003
    ..The right hepatic artery was obstructed due to direct invasion of tumor. There were diffuse thrombi in the left portal branches surrounded by tumor infiltrating along Glisson's sheath to the peripheral portion of the left lobe...
  28. ncbi request reprint Limitation of portal vein embolization for extension of hepatectomy indication in patients with hepatocellular carcinoma
    Kazuhiro Hirohashi
    Gastroenterological and Hepato Biliary Pancreatic Surgery Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:1084-7. 2004
    ....
  29. ncbi request reprint Surgical treatment for hepatocellular carcinoma detected after successful interferon therapy
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    Surg Today 37:285-90. 2007
    ..The risk factors for tumor recurrence after a liver resection for HCC detected after successful interferon therapy were investigated to determine the appropriate operative method for such HCC...
  30. doi request reprint Features and outcome after liver resection for non-B non-C hepatocellular carcinoma
    Kazuhisa Kaneda
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 59:1889-92. 2012
    ..We investigated the clinicopathological findings and outcome after surgery for hepatocellular carcinoma in patients without hepatitis B or C virus infection...
  31. ncbi request reprint A mixed hepatocellular carcinoma and cholangiocarcinoma: dual expression of biliary-type cytokeratin and hepatocyte specific marker
    Shogo Tanaka
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:839-41. 2004
    ..Additionally, immunohistochemical examination revealed that some tumor cells in the transitional area were immunoreactive for both cytokeratin 19 and hepatocyte paraffin 1...
  32. ncbi request reprint Primary liver cancer with dual expression of hepatocyte and bile duct epithelial markers
    Takahiro Uenishi
    Second Department of Surgery, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 49:1092-4. 2002
    ..Since the tumor expressed dual phenotypic markers of both hepatocytes and bile duct cells, the tumor might have an intermediate phenotype between hepatocytes and bile duct cells...
  33. doi request reprint Risk factors for postoperative recurrence of non-B non-C hepatocellular carcinoma
    Hiroji Shinkawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    J Hepatobiliary Pancreat Sci 17:291-5. 2010
    ..Recently, however, the proportion of non-B non-C hepatocellular carcinomas has been increasing. It is necessary to determine the optimal surgical approach for non-B non-C hepatocellular carcinoma...
  34. ncbi request reprint Surgically treated cases of mixed hepatocellular carcinoma and cholangiocarcinoma
    Takahiro Uenishi
    Second Department of Surgery, Osaka City University Medical School, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 49:1083-6. 2002
    ..The patient died of multiple recurrent tumors in the remnant liver 3 months after surgery. Surgical control of mixed hepatocellular carcinoma and cholangiocarcinoma is difficult...
  35. ncbi request reprint Prognostic effects of causative virus in hepatocellular carcinoma according to the Japan integrated staging (JIS) score
    Shoji Kubo
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    J Gastroenterol 40:972-9. 2005
    ..The Japan integrated staging (JIS) score is recognized to be useful in managing hepatocellular carcinoma (HCC). We evaluated the effects of the causative virus in patients stratified by this system...
  36. ncbi request reprint Hepatitis C virus infection as a likely etiology of intrahepatic cholangiocarcinoma
    Satoshi Yamamoto
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery and Public Health, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka 545 8585, Japan
    Cancer Sci 95:592-5. 2004
    ..As liver status worsened, the adjusted OR for ICC tended to increase. HCV infection is a likely etiology of ICC in Japan...
  37. ncbi request reprint Incidence and management of bile leakage after hepatic resection for malignant hepatic tumors
    Shogo Tanaka
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Graduate School of Medicine, Osaka City University, Osaka, Japan
    J Am Coll Surg 195:484-9. 2002
    ..Bile leakage is one of the frequent and disturbing complications of hepatic resection...
  38. ncbi request reprint Clinicopathologic features in patients with long-term survival following resection for intrahepatic cholangiocarcinoma
    Takahiro Uenishi
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 50:1069-72. 2003
    ..As the overall prognosis for patients with intrahepatic cholangiocarcinoma is extremely poor, it is important to identify specific clinicopathologic features associated with long-term survival after hepatic resection for this tumor...
  39. ncbi request reprint Clinicopathological implications of immunohistochemically demonstrated mucin core protein expression in hepatocellular carcinoma
    Tsuyoshi Ichikawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    J Hepatobiliary Pancreat Surg 13:245-51. 2006
    ....
  40. ncbi request reprint Surgical strategy for hepatocellular carcinoma originating in the caudate lobe
    Takatsugu Yamamoto
    Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan
    Surgery 135:595-603. 2004
    ..We reviewed the clinicopathologic findings of patients who underwent liver resection of caudate HCC and correlated the outcome with the surgical strategy...
  41. ncbi request reprint HBV DNA integration and HBV-transcript expression in non-B, non-C hepatocellular carcinoma in Japan
    Akihiro Tamori
    Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Med Virol 71:492-8. 2003
    ..These results suggested that occult HBV infection might play an important role in hepatocarcinogenesis in non-B, non-C patients with anti-HBc and that excessive alcohol intake might be related to HCC in non-B, non-C patients in Japan...
  42. ncbi request reprint Multifocal hepatocellular carcinoma in patients undergoing living-related liver transplantation
    Kazuhiro Hirohashi
    Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 50:1617-20. 2003
    ..Foci of hepatocellular carcinoma undetected preoperatively are unlikely to effect prognosis when total hepatectomy is performed in the context of living-related liver transplantation...
  43. ncbi request reprint Serosal invasion in TNM staging of mass-forming intrahepatic cholangiocarcinoma
    Takahiro Uenishi
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    J Hepatobiliary Pancreat Surg 12:479-83. 2005
    ..Serosal invasion is not considered in the designation established by the International Union Against Cancer...
  44. ncbi request reprint Immunohistologic attempt to find carcinogenesis from hepatic progenitor cell in hepatocellular carcinoma
    Takatsugu Yamamoto
    Department of Surgery, Ishikiri Seiki Hospital, Osaka, Japan
    Dig Surg 22:364-70. 2005
    ..To clarify whether hepatocellular carcinoma (HCC) originates from hepatic progenitor cells and whether there is any correlation with the clinicopathologic factors of HCC, we reviewed 217 resected HCC specimens...
  45. ncbi request reprint Adenomyoma of the common hepatic duct mimicking bile duct cancer: report of a case
    Seikan Hai
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    Surg Today 37:608-11. 2007
    ....
  46. ncbi request reprint Convenience of a tape-guiding technique in different types of hepatectomy
    Hiromu Tanaka
    Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 55:160-3. 2008
    ..The liver hanging maneuver is widely used in right lobectomy to resect huge tumors and harvest living donors. The convenience of tape assistance in other types of hepatectomy is not well known...
  47. ncbi request reprint A histopathological study on combined hepatocellular and cholangiocarcinoma: cholangiocarcinoma component is originated from hepatocellular carcinoma
    Tomoko Wakasa
    The Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    Hepatogastroenterology 54:508-13. 2007
    ..Combined hepatocellular and cholangiocarcinoma of the liver is relatively infrequent, and its pathogenesis remains obscure. The aim of this study is to investigate its clinical and pathological features and proliferative activity...
  48. ncbi request reprint Intrahepatic cystadenocarcinoma with pleural dissemination: a case report
    Seikan Hai
    Osaka City University, Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Osaka City Med J 49:61-5. 2003
    ..We believe that intrahepatic cystic lesions should be approached aggressively, including the use of exploratory laparotomy/laparoscopy to be certain that cancer is not present...
  49. ncbi request reprint Curative resection of a huge bile duct cancer without pancreatoduodenectomy
    Shogo Tanaka
    Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:1292-4. 2004
    ..Longitudinal spread was more extensive hepatopetally than hepatofugally. The patient is alive and well without any complaints 8 months after surgery...
  50. doi request reprint Effects of antiviral therapy on long-term outcome after liver resection for hepatitis B virus-related hepatocellular carcinoma
    Yorihisa Urata
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    J Hepatobiliary Pancreat Sci 19:685-96. 2012
    ..We investigated the effects of nucleos(t)ide analogues (NAs) on long-term outcome in patients following curative treatment for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)...
  51. ncbi request reprint [Hepatic failure after liver resection in patients with cirrhosis]
    Shoji Kubo
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nihon Geka Gakkai Zasshi 105:669-73. 2004
    ..Careful preoperative evaluation of the hepatic functional reserve and the severity of active hepatitis, and adequate selection of surgical method are important to prevent postoperative hepatic failure...
  52. doi request reprint Outcomes of hepatic resection for hepatolithiasis
    Takahiro Uenishi
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Am J Surg 198:199-202. 2009
    ..Hepatic resection is main approach to treatment of hepatolithiasis, but the long-term follow-up results of hepatic resection for hepatolithiasis are rarely reported...
  53. doi request reprint Frequent detection of hepatitis B virus DNA in hepatocellular carcinoma of patients with sustained virologic response for hepatitis C virus
    Akihiro Tamori
    Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Med Virol 81:1009-14. 2009
    ..Mutation in 'a' determinant of HBsAg was found in three HCC of group A. Occult HBV infection may be one of the most important risk factors in hepatocarcinogenesis of Japanese patients with sustained virologic response...
  54. ncbi request reprint Sequencing of human-viral DNA junctions in hepatocellular carcinoma from patients with HCV and occult HBV infection
    Akihiro Tamori
    Department of Hepatology, Osaka City University Graduate School of Medicine, Japan
    J Med Virol 69:475-81. 2003
    ..In conclusion, integrated HBV was detected in some patients with HCV infection; in these patients, the integrated DNA was associated with accelerated hepatocarcinogenesis...
  55. ncbi request reprint Expression of bile duct-type cytokeratin in hepatocellular carcinoma in patients with hepatitis C virus and prior hepatitis B virus infection
    Takahiro Uenishi
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Cancer Lett 178:107-12. 2002
    ..Some HCCs develop from the hepatic progenitor cells in patients with HCV infection and prior HBV infection, which may affect the clinicopathologic findings of HCV-related HCCs...
  56. ncbi request reprint S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats
    Hiroji Shinkawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Osaka City Med J 55:61-9. 2009
    ..S-allylcysteine (SAC), an ingredient of aged garlic extract, is known to have antioxidant and hepatoprotective effects. The aim of this study was to investigate the antifibrotic effects of SAC in the liver...
  57. ncbi request reprint A long-term survival case underwent repeated hepatic arterial infusion chemotherapy with portal branch ligation and wrapping of the liver using sheets for hepatocellular carcinoma
    Takahiro Uenishi
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Hepatogastroenterology 49:1423-4. 2002
    ..Hepatic arterial infusion chemotherapy combined with portal branch occlusion and decollateralization is a new therapeutic method for unresectable hepatocellular carcinoma...
  58. ncbi request reprint Histologic bile duct invasion by a mass-forming intrahepatic cholangiocarcinoma
    Kazuhiro Hirohashi
    Department of Hepato Biliary Pancreatic and Gastroenterological Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    J Hepatobiliary Pancreat Surg 9:233-6. 2002
    ..We carried out this study to determine a surgical strategy for patients with bile duct invasion of these tumors...
  59. ncbi request reprint Previous or occult hepatitis B virus infection in hepatitis B surface antigen-negative and anti-hepatitis C-negative patients with hepatocellular carcinoma
    Kazuki Ohba
    Second Department of Surgery, Osaka City University Medical School, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Surg Today 34:842-8. 2004
    ....
  60. ncbi request reprint Risk factors for postoperative delirium after liver resection for hepatocellular carcinoma
    Yasuko Yoshimura
    Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, 545 8585, Osaka, Japan
    World J Surg 28:982-6. 2004
    ..These findings indicate that multiple factors, including advanced age, impaired liver function, and advanced cancer stage, affect the development of postoperative delirium after liver resection for hepatocellular carcinoma...
  61. ncbi request reprint Effect of long-term postoperative interferon therapy on intrahepatic recurrence and survival rate after resection of hepatitis C virus-related hepatocellular carcinoma
    Shuhei Nishiguchi
    Department of Hepatology, Osaka City University Medical School, Osaka, Japan
    Intervirology 48:71-5. 2005
    ..This study was aimed at evaluating the effects of interferon (IFN)-alpha on survival rate after resection of hepatocellular carcinoma...
  62. ncbi request reprint Postoperative survival in intrahepatic cholangiocarcinoma showing intraductal growth
    Seikan Hai
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 52:374-7. 2005
    ....
  63. ncbi request reprint Serum concentration of type IV collagen 7S domain as a marker for increased risk of recurrence after liver resection for hepatocellular carcinoma
    Shuichi Kawai
    Second Department of Surgery, Osaka City University Medical School, Osaka, Japan
    Dig Surg 20:201-8. 2003
    ..We investigated the usefulness of measuring the serum 7S collagen concentration as a risk factor for recurrence after liver resection for hepatocellular carcinoma (HCC)...
  64. ncbi request reprint Nonoprerative management of obstructive jaundice caused by a benign hepatic cyst
    Masao Ogawa
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 50:95-9. 2004
    ..There were no complications or side-effects. The instillation of minocycline hydrochloride is a useful alternative to ethanol instillation for treating benign hepatic cysts, even when the cyst is causing obstructive jaundice...
  65. ncbi request reprint Secondary hemocholecyst after radiofrequency ablation therapy for hepatocellular carcinoma
    Takatsugu Yamamoto
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    J Gastroenterol 38:399-403. 2003
    ..Cholecystectomy is indicated for hemocholecyst because spontaneous liquefication and drainage of a clot in the gallbladder usually does not occur...
  66. ncbi request reprint Hepatocellular carcinoma arising from nonalcoholic steatohepatitis: report of two cases
    Seikan Hai
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Abeno Ku, Japan
    Surg Today 36:390-4. 2006
    ..Thus, clinical follow-up and screening for HCC should be done for patients with hepatic fibrosis caused by NASH, even though this form of hepatitis is an uncommon cause of HCC...
  67. ncbi request reprint Usefulness of three-dimensional computed tomography in a living-donor extended right lobe liver transplantation
    Akishige Kanazawa
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Liver Transpl 8:1076-9. 2002
    ....
  68. ncbi request reprint Living-related liver transplantation in a patient with end-stage hepatolithiasis and a biliary-bronchial fistula
    Kazuhiro Hirohashi
    Department of Hepatobiliary Pancreatic and Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan
    Hepatogastroenterology 51:822-4. 2004
    ..The postoperative course following LRLT was uncomplicated, and hepatic function was good. Careful management of infection and adequate graft size are essential for successful LRLT in patients with end-stage hepatolithiasis...
  69. ncbi request reprint Bile leakage after living donor liver transplantation demonstrated with hepatobiliary scan using 9mTc-PMT
    Akishige Kanazawa
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, Japan
    Ann Nucl Med 17:507-9. 2003
    ..Hepatobiliary scan is useful in determining the therapeutic plan as well as detection of bile leakage and identification of leakage points after living donor liver transplantation...
  70. ncbi request reprint Treatment with STI571, a tyrosine kinase inhibitor, for gastrointestinal stromal tumor with peritoneal dissemination and multiple liver metastases
    Satoshi Yamamoto
    Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    J Gastroenterol 38:896-9. 2003
    ..Gastrointestinal stromal tumors (GISTs) are usually refractory to standard chemotherapeutic agents. We successfully treated a patient with a tyrosine kinase inhibitor (STI571) for GIST with peritoneal dissemination and liver metastases...
  71. ncbi request reprint Pseudoaneurysm of the dorsal pancreatic artery with obstruction of the celiac axis after pancreatoduodenectomy: report of a case
    Akishige Kanazawa
    Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka, 545 8585, Japan
    Surg Today 35:332-5. 2005
    ..This case demonstrates that the dissection of arteries that have developed around the head of the pancreas must be considered in patients with obstruction of the celiac axis...
  72. doi request reprint Comparison of the outcomes between anatomical resection and limited resection for single hepatocellular carcinomas no larger than 5 cm in diameter: a single-center study
    Osamu Yamazaki
    Department of Surgery, Osaka City General Hospital, 2 13 22 Miyakojimahondori Miyakojima ku, Osaka, 534 0021, Japan
    J Hepatobiliary Pancreat Sci 17:349-58. 2010
    ..This study aimed to compare the survival impact of anatomical resection with that of limited resection, in patients with single HCCs no larger than 5 cm in diameter...
  73. ncbi request reprint Asymptomatic thrombosis as a late complication of a retrohepatic vena caval graft performed for primary leiomyosarcoma of the inferior vena cava: report of a case
    Kazuhiro Hirohashi
    Department of Hepato Biliary Pancreatic and Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Japan
    Surg Today 32:1012-5. 2002
    ..The occurrence of thrombosis must be kept in mind in the long-term follow-up of such cases...
  74. doi request reprint Impact of laparoscopic liver resection for hepatocellular carcinoma with F4-liver cirrhosis
    Akishige Kanazawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City General Hospital, 2 13 22 Miyakojima Hondori, Miyakojima ku, Osaka 534 0021, Japan
    Surg Endosc 27:2592-7. 2013
    ..Although the utility of laparoscopic liver resection for hepatocellular carcinoma (HCC) has been recognized in recent years, the impact of the laparoscopic liver resection for HCC with complete liver cirrhosis (F4) is still unknown...
  75. pmc Laparoscopic splenectomy for histiocytic sarcoma of the spleen
    Satoshi Yamamoto
    Satoshi Yamamoto, Tadashi Tsukamoto, Akishige Kanazawa, Sadatoshi Shimizu, Keiichiro Morimura, Takahiro Toyokawa, Zhang Xiang, Katsunobu Sakurai, Tatsunari Fukuoka, Kayo Yoshida, Mamiko Takii, Department of Hepato Biliary Pancreatic Surgery, Osaka City General Hospital, Osaka 534 0021, Japan
    World J Gastrointest Surg 5:129-34. 2013
    ..In such cases, splenic artery ligation can markedly reduce the size of the spleen, thus facilitating the procedure. The case reported herein suggests that laparoscopic splenectomy may be useful for the treatment of splenic malignancy...
  76. doi request reprint Laparoscopic liver resection for treating recurrent hepatocellular carcinoma
    Akishige Kanazawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City General Hospital, 2 13 22 Miyakojima hondoori, Miyakojima ku, Osaka 534 0021, Japan
    J Hepatobiliary Pancreat Sci 20:512-7. 2013
    ..It is still unknown whether laparoscopic liver resection is suitable for recurrent hepatocellular carcinoma (HCC) after previous curative hepatic resection...
  77. doi request reprint FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma
    Tokuzo Arao
    Department of Genome Biology, Kinki University Faculty of Medicine, Osaka, Japan
    Hepatology 57:1407-15. 2013
    ..Finally, an in vivo study revealed that treatment with a low dose of sorafenib was partially effective for stably and exogenously expressed FGF4 tumors, while being less effective in tumors expressing EGFP or FGF3...
  78. doi request reprint Lymphoid hyperplasia detected as a single mass in the gallbladder: report of a case
    Satoshi Yamamoto
    Department of Hepato Biliary Pancreatic Surgery, Osaka City General Medical Hospital, 2 13 22 Miyakojima Hondori, Miyakojima ku, Osaka 534 0021, Japan
    Surg Today 42:1244-7. 2012
    ..The lymphocytes were morphologically normal. We diagnosed lymphoid hyperplasia with chronic cholecystitis. Lymphoid hyperplasia of the gallbladder is extremely rare...
  79. ncbi request reprint Intracystic hemorrhage with spontaneous rupture of liver cyst complicated by infection: a case report
    Akishige Kanazawa
    Department of Surgery, Asakayama General Hospital, Department of Gastroenterological and Hepato Biliary Pancreatic Surgery, Osaka City University, Graduate School of Medicine, Japan
    Osaka City Med J 49:57-60. 2003
    ..Transhepatic cyst drainage combined with antibiotic therapy and intracystic ethanol injection may be a useful and minimally invasive method for liver cysts with these complications, especially in compromised patients...
  80. ncbi request reprint Resection of needle-tract implantation after percutaneous puncture for hepatocellular carcinoma
    Taichi Shuto
    J Gastroenterol 39:907-8. 2004
  81. ncbi request reprint [A case of a small intrahepatic cholangiocarcinoma treated with microwave coagulation therapy]
    Tsuyoshi Ichikawa
    Department of Hepato Biliary Pancreatic Surgery, Osaka City University Graduate School of Medicine
    Nihon Shokakibyo Gakkai Zasshi 102:1299-304. 2005