Tadashi Kimura

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. ncbi request reprint Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium
    T Kimura
    Faculty of Medicine, Osaka University, 2 2, Yamadaoka, Suita, Osaka, 5650871, Japan
    Biochem Biophys Res Commun 264:86-92. 1999
  2. pmc A cost-benefit analysis on the specialization in departments of obstetrics and gynecology in Japan
    Junyi Shen
    Faculty of International Studies, Hiroshima City University, 3 4 1 Ozuka Higashi, Asa Minami Ku, Hiroshima 7313194, Japan
    Health Econ Rev 2:2. 2012
  3. doi request reprint Molecular analysis of parturition via oxytocin receptor expression
    Tadashi Kimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Taiwan J Obstet Gynecol 52:165-70. 2013
  4. ncbi request reprint Clinical over- and under-estimation in patients who underwent hysterectomy for atypical endometrial hyperplasia diagnosed by endometrial biopsy: the predictive value of clinical parameters and diagnostic imaging
    Tadashi Kimura
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovasucular Diseases, 1 3 3 Nakamichi, Higashinari, 5378511, Osaka, Japan
    Eur J Obstet Gynecol Reprod Biol 108:213-6. 2003
  5. ncbi request reprint Molecular regulation of the oxytocin receptor in peripheral organs
    T Kimura
    Department of Gynaecology, Osaka Medical Centre for Cancer and Cardiovascular Diseases, 1 3 3, Nakamichi, Higashinari ku, Osaka 5378511, Japan
    J Mol Endocrinol 30:109-15. 2003
  6. ncbi request reprint Effectiveness of hormonal tourniquet by vasopressin during myomectomy through vasopressin V1a receptor ubiquitously expressed in myometrium
    Tadashi Kimura
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Gynecol Obstet Invest 54:125-31. 2002
  7. ncbi request reprint Effect of proteasome pathway on initiation of mouse labor induced by antiprogesterone
    Tadashi Kimura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    Am J Reprod Immunol 52:317-22. 2004
  8. ncbi request reprint In vivo gene transfer into the mouse uterus: a powerful tool for investigating implantation physiology
    Tadashi Kimura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 5650871, Japan
    J Reprod Immunol 67:13-20. 2005
  9. doi request reprint Expression of aldehyde dehydrogenase 1 (ALDH1) in endometrioid adenocarcinoma and its clinical implications
    Nur Rahadiani
    Department of Pathology, Osaka University Graduate School of Medicine, Suita, Japan
    Cancer Sci 102:903-8. 2011
  10. doi request reprint Impact of the addition of concurrent chemotherapy to pelvic radiotherapy in surgically treated stage IB1-IIB cervical cancer patients with intermediate-risk or high-risk factors: a 13-year experience
    Mika Okazawa
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka University Graduate School of Medicine, Japan
    Int J Gynecol Cancer 23:567-75. 2013

Collaborators

Detail Information

Publications126 found, 100 shown here

  1. ncbi request reprint Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium
    T Kimura
    Faculty of Medicine, Osaka University, 2 2, Yamadaoka, Suita, Osaka, 5650871, Japan
    Biochem Biophys Res Commun 264:86-92. 1999
    ..The highly specific binding of hMafF to the US-2 motif in the human OTR gene, together with its pattern of expression, supports a role for hMafF in OTR gene upregulation at term...
  2. pmc A cost-benefit analysis on the specialization in departments of obstetrics and gynecology in Japan
    Junyi Shen
    Faculty of International Studies, Hiroshima City University, 3 4 1 Ozuka Higashi, Asa Minami Ku, Hiroshima 7313194, Japan
    Health Econ Rev 2:2. 2012
    ..The results of these sensitivity analyses suggest that the specialization is valid in the sense that all the estimated benefit-cost ratios are above 1.0 in any case...
  3. doi request reprint Molecular analysis of parturition via oxytocin receptor expression
    Tadashi Kimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Taiwan J Obstet Gynecol 52:165-70. 2013
    ..Recent progress in molecular biology has augmented our knowledge about OTR regulation in the uterus at the transcription level, although the totality of preparation for labor through OTR expression is still obscure. ..
  4. ncbi request reprint Clinical over- and under-estimation in patients who underwent hysterectomy for atypical endometrial hyperplasia diagnosed by endometrial biopsy: the predictive value of clinical parameters and diagnostic imaging
    Tadashi Kimura
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovasucular Diseases, 1 3 3 Nakamichi, Higashinari, 5378511, Osaka, Japan
    Eur J Obstet Gynecol Reprod Biol 108:213-6. 2003
    ..e. to determine the rates of underestimation (endometrial cancer), equivalent diagnosis (atypical hyperplasia), and overestimation (hyperplasia without atypia or non-hyperplastic lesion)...
  5. ncbi request reprint Molecular regulation of the oxytocin receptor in peripheral organs
    T Kimura
    Department of Gynaecology, Osaka Medical Centre for Cancer and Cardiovascular Diseases, 1 3 3, Nakamichi, Higashinari ku, Osaka 5378511, Japan
    J Mol Endocrinol 30:109-15. 2003
    ..These findings taken together indicate that the oxytocin receptor is regulated in a very complicated manner, and the transcriptional regulatory elements critical for this regulation should be investigated further...
  6. ncbi request reprint Effectiveness of hormonal tourniquet by vasopressin during myomectomy through vasopressin V1a receptor ubiquitously expressed in myometrium
    Tadashi Kimura
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Gynecol Obstet Invest 54:125-31. 2002
    ..No serious complications occurred on account of the vasopressin injection. We conclude that intraoperative vasopressin injection is effective as a hormonal tourniquet even in GnRH agonist-pretreated myomectomy...
  7. ncbi request reprint Effect of proteasome pathway on initiation of mouse labor induced by antiprogesterone
    Tadashi Kimura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    Am J Reprod Immunol 52:317-22. 2004
    ..However, expression profiling has revealed that many molecules are also down-regulated. The effect of down-regulation of molecules by protein degradation on parturition is not known...
  8. ncbi request reprint In vivo gene transfer into the mouse uterus: a powerful tool for investigating implantation physiology
    Tadashi Kimura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 5650871, Japan
    J Reprod Immunol 67:13-20. 2005
    ..Based on this knowledge, we should further analyse the pathophysiology of human implantation failure using human materials...
  9. doi request reprint Expression of aldehyde dehydrogenase 1 (ALDH1) in endometrioid adenocarcinoma and its clinical implications
    Nur Rahadiani
    Department of Pathology, Osaka University Graduate School of Medicine, Suita, Japan
    Cancer Sci 102:903-8. 2011
    ..010 for overall survival [OS]), and high ALDH1 expression was an independent factor for poor prognosis. Aldehyde dehydrogenase 1 is a candidate for CIC marker for uterine endometrioid adenocarcinoma...
  10. doi request reprint Impact of the addition of concurrent chemotherapy to pelvic radiotherapy in surgically treated stage IB1-IIB cervical cancer patients with intermediate-risk or high-risk factors: a 13-year experience
    Mika Okazawa
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka University Graduate School of Medicine, Japan
    Int J Gynecol Cancer 23:567-75. 2013
    ..To identify groups of patients who derive clinical benefit from postoperative adjuvant concurrent chemoradiotherapy (CCRT), we retrospectively investigated the survival outcomes of surgically treated early-stage cervical cancer patients...
  11. ncbi request reprint Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor
    Hitomi Nakamura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 5650871, Japan
    Biochem Biophys Res Commun 321:886-92. 2004
    ..Taken together, these findings indicate that NF-kappaB activation determines the timing of the implantation, at least in part, via control of LIF expression...
  12. pmc Vascular endothelial growth factor is a promising therapeutic target for the treatment of clear cell carcinoma of the ovary
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Mol Cancer Ther 9:2411-22. 2010
    ..Bevacizumab may be efficacious not only as a first-line treatment but also as a second-line treatment of recurrent disease in patients previously treated with cisplatin...
  13. doi request reprint Endometrial carcinoma: better prognosis for asymptomatic recurrences than for symptomatic cases found by routine follow-up
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Int J Clin Oncol 15:406-12. 2010
    ..The aim of this study was to determine if there is a prognostic value for the presence of symptoms at the time of recurrence detection in surgically resected endometrial carcinoma patients...
  14. doi request reprint Cervical non-squamous carcinoma: an effective combination chemotherapy of taxane, anthracycline and platinum for advanced or recurrent cases
    Toshihiro Kimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Eur J Obstet Gynecol Reprod Biol 164:200-4. 2012
    ..The aim of the present study was to analyze the safety and efficacy of a combination chemotherapy for this disease using taxane, anthracycline, and platinum...
  15. doi request reprint Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells
    Seiji Ogata
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Int J Gynecol Cancer 19:1473-80. 2009
    ..Our findings suggest that fasudil might be useful to prevent the progression of ovarian cancer in clinical settings...
  16. doi request reprint Taxane-sensitivity of ovarian carcinomas previously treated with paclitaxel and carboplatin
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Cancer Chemother Pharmacol 71:1411-6. 2013
    ....
  17. ncbi request reprint Dissection of unsuspicious para-aortic lymph nodes does not improve prognosis of advanced endometrial carcinoma with intra- or extra-abdominal metastasis
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Anticancer Res 31:4513-7. 2011
    ..The aim of this study was to analyze the significance of dissection of unsuspicious para-aortic lymph nodes (PAN) in patients with advanced endometrial carcinomas with intra- or extra-abdominal metastasis...
  18. doi request reprint Salvage chemotherapy for recurrent or persistent clear cell carcinoma of the ovary: a single-institution experience for a series of 20 patients
    Kiyoshi Yoshino
    Department of Obstetrics and Gynecology, Osaka University, Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
    Int J Clin Oncol 18:148-53. 2013
    ..The purpose of this study was to review our extensive institutional experiences with recurrent or persistent CCC with the aim of finding a more effective chemotherapy regimen...
  19. ncbi request reprint Comparison of the prognoses of FIGO stage I to stage II adenosquamous carcinoma and adenocarcinoma of the uterine cervix treated with radical hysterectomy
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Gynecol Cancer 22:1389-97. 2012
    ..To evaluate the significance of adenosquamous carcinoma (ASC) compared with adenocarcinoma (AC) in the survival of surgically treated early-stage cervical cancer...
  20. pmc Investigating the relative efficacies of combination chemotherapy of paclitaxel/carboplatin, with or without anthracycline, for endometrial carcinoma
    Kazuko Fujiwara
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1179 3, Higashinari ku Nakamichi, Osaka 537 8511, Japan
    Arch Gynecol Obstet 285:1447-53. 2012
    ..The aim of our present study was to conduct the required clinical evaluations of the relative effectiveness of TC compared to TEC...
  21. doi request reprint Postpartum outcome of cervical intraepithelial neoplasia in pregnant women determined by route of delivery
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Reprod Sci 16:1034-9. 2009
    ..We also find that there is a significantly more frequent postpartum regression of biopsy-proven CIN lesions following a vaginal delivery compared to cesarean section (P = .042 by Fisher exact test, Odds ratio = 6.55; 95% CI: 1.13-37.8)...
  22. doi request reprint Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 63:137-43. 2010
    ..The aim of our study was to investigate the expression of RCAS1 protein in the uteri of normal pregnant mice...
  23. doi request reprint A phase I study of concurrent weekly carboplatin and paclitaxel combined with intensity-modulated pelvic radiotherapy as an adjuvant treatment for early-stage cervical cancer patients with positive pelvic lymph nodes
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Gynecol Cancer 23:1279-86. 2013
    ....
  24. doi request reprint The prognostic significance of multiple pelvic node metastases in cervical cancer patients treated with radical hysterectomy plus adjuvant chemoradiotherapy
    Mika Okazawa
    Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Int J Gynecol Cancer 22:490-7. 2012
    ..We investigated the prognostic significance of multiple pelvic node metastases in cervical cancer patients who were treated with radical hysterectomy plus adjuvant chemoradiotherapy...
  25. doi request reprint Concurrent weekly nedaplatin, external beam radiotherapy and high-dose-rate brachytherapy in patients with FIGO stage IIIb cervical cancer: a comparison with a cohort treated by radiotherapy alone
    Seiji Mabuchi
    Departments of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    Gynecol Obstet Invest 69:224-32. 2010
    ....
  26. doi request reprint The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Obstet Gynecol 203:364.e6-364.e12. 2010
    ..We hypothesized that RCAS1 protein gene silencing might affect blood pressure and proteinuria in pregnant mice...
  27. ncbi request reprint Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women
    Koichiro Shimoya
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
    Maturitas 54:141-8. 2006
    ..The aim of the present study was to examine whether there is an association between the SLPI concentration in the cervicovaginal secretion (CS) and vaginal complaints of post-menopausal women...
  28. doi request reprint Postoperative concurrent nedaplatin-based chemoradiotherapy improves survival in early-stage cervical cancer patients with adverse risk factors
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Gynecol Oncol 115:482-7. 2009
    ..The aim of this study was to evaluate the efficacy of postoperative nedaplatin-based concurrent chemoradiotherapy (CCRT) in patients with FIGO stage IA2-IIB cervical cancer with adverse risk factors...
  29. doi request reprint Metal transcription factor-1 is involved in hypoxia-dependent regulation of placenta growth factor in trophoblast-derived cells
    Fumihito Nishimoto
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Suita City, Osaka, Japan
    Endocrinology 150:1801-8. 2009
    ..Taken together, these findings suggest that MTF-1 is involved in hypoxia-dependent regulation of PlGF in trophoblast-derived cells...
  30. doi request reprint Endometrial cancer: preoperative staging using three-dimensional T2-weighted turbo spin-echo and diffusion-weighted MR imaging at 3.0 T: a prospective comparative study
    Masatoshi Hori
    Department of Radiology, Osaka University Graduate School of Medicine, D1, 2 2, Yamadaoka, Suita, Osaka, 565 0871, Japan
    Eur Radiol 23:2296-305. 2013
    ....
  31. ncbi request reprint Simple and highly efficient method for transient in vivo gene transfer to mid-late pregnant mouse uterus
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Reprod Immunol 70:59-69. 2006
    ..Thus, we demonstrated that this transient gene transfer method is highly efficient and minimally invasive, and expect that this procedure will be a useful tool to analyze the pathophysiology of pregnancy-related disorders...
  32. doi request reprint Conization using the Shimodaira-Taniguchi procedure for adenocarcinoma in situ of the uterine cervix
    Kosuke Hiramatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka, 565 0871, Japan
    Eur J Obstet Gynecol Reprod Biol 168:218-21. 2013
    ..The aim of the present study was to analyze the surgical efficacy of the Shimodaira-Taniguchi conization procedure for adenocarcinoma in situ (AIS) of the uterine cervix...
  33. doi request reprint WT1 peptide immunotherapy for gynecologic malignancies resistant to conventional therapies: a phase II trial
    Takashi Miyatake
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    J Cancer Res Clin Oncol 139:457-63. 2013
    ..The aim of the present study was to analyze the long-term survival effects of WT1 peptide vaccine, in addition to its anti-tumor effects and toxicity...
  34. ncbi request reprint Level of S100B protein expression in the amnion at various gestational ages in the third trimester of normal pregnancies
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Acta Obstet Gynecol Scand 86:915-20. 2007
    ..The aim of our study was to assess the correlation between S100B protein expression in the amnion, amniotic fluid and gestational age in the third trimester of uncomplicated pregnancies...
  35. doi request reprint Aldosterone stimulates the proliferation of uterine leiomyoma cells
    Aki Isobe
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Gynecol Endocrinol 26:372-7. 2010
    ..Aldosterone is a key biological peptide in the renin-angiotensin-aldosterone system that regulates blood pressure. In this study, we investigated the siginificant stimulatory effect of aldosterone on leiomyoma cells proliferation...
  36. doi request reprint Effects of 4-hydroxy-2-nonenal, a major lipid peroxidation-derived aldehyde, and N-acetylcysteine on the cyclooxygenase-2 expression in human uterine myometrium
    Kumiko Temma-Asano
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Gynecol Obstet Invest 72:37-42. 2011
    ..We also examined the effect of N-acetylcysteine (NAC) on 4-HNE-induced COX-2 expression...
  37. ncbi request reprint Salvage chemotherapy for ovarian carcinoma recurring during or after consolidation chemotherapy with paclitaxel
    Yukari Miyoshi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Anticancer Res 31:4613-7. 2011
    ..The aim of the study was to analyze the effectiveness of salvage chemotherapy for recurring ovarian carcinoma during or after consolidation chemotherapy...
  38. doi request reprint Intraoperative frozen section assessment of myometrial invasion and histology of endometrial cancer using the revised FIGO staging system
    Hiromi Ugaki
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Int J Gynecol Cancer 21:1180-4. 2011
    ....
  39. pmc Second-line chemotherapy for advanced or recurrent endometrial carcinoma previously treated with paclitaxel and carboplatin, with or without epirubicin
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Cancer Chemother Pharmacol 67:829-35. 2011
    ....
  40. doi request reprint A case of complete hydatidiform mole with coexistent fetus: conclusive diagnosis of androgenesis of the molar placenta by variation of paternal acrocentric short arms
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Am J Perinatol 27:143-9. 2010
    ..We describe the clinical course of our case and review some literature concerning complete hydatidiform mole with coexisting fetus...
  41. doi request reprint Radical hysterectomy with adjuvant radiotherapy versus definitive radiotherapy alone for FIGO stage IIB cervical cancer
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Gynecol Oncol 123:241-7. 2011
    ..The aim of this study was to compare the treatment outcomes and adverse effects of radical hysterectomy followed by adjuvant radiotherapy with definitive radiotherapy alone in patients with FIGO stage IIB cervical cancer...
  42. doi request reprint Endometrial carcinoma with extra-abdominal metastasis: improved prognosis following cytoreductive surgery
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Ann Surg Oncol 17:1111-7. 2010
    ..The prognosis for stage IVb cases with extra-abdominal metastases is extremely poor, with no current consensus regarding treatment. The aim of the present study was to examine the benefits of cytoreductive surgery for such cases...
  43. doi request reprint Postoperative whole pelvic radiotherapy plus concurrent chemotherapy versus extended-field irradiation for early-stage cervical cancer patients with multiple pelvic lymph node metastases
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Gynecol Oncol 120:94-100. 2011
    ....
  44. doi request reprint Maternal carbon dioxide level during labor and its possible effect on fetal cerebral oxygenation: mini review
    Takuji Tomimatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    J Obstet Gynaecol Res 39:1-6. 2013
    ..Thus, maternal hyperventilation may interfere with optimal fetal cerebral oxygenation. Here, we provide a brief overview of the literature relevant to this issue...
  45. doi request reprint Plasma membrane proteomics identifies bone marrow stromal antigen 2 as a potential therapeutic target in endometrial cancer
    Takuhei Yokoyama
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Cancer 132:472-84. 2013
    ..The combination of biotinylation-based enrichment of cell-surface proteins and iTRAQ analysis should be a useful screening method for future discovery of potential therapeutic targets...
  46. doi request reprint The first 2 cases of granulocyte colony-stimulating factor producing adenocarcinoma of the uterine cervix
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Int J Gynecol Pathol 29:483-7. 2010
    ..These cases strongly indicate the aggressive nature of the G-CSF-producing cervical adenocarcinomas...
  47. doi request reprint Prediction of progression-free survival and response to paclitaxel plus carboplatin in patients with recurrent or advanced cervical cancer
    Takeshi Hisamatsu
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Gynecol Cancer 22:623-9. 2012
    ..The aim of this study was to identify predictors of the response to paclitaxel-carboplatin chemotherapy (TC) in recurrent or patients with advanced cervical cancer...
  48. ncbi request reprint NF-kappaB activation at implantation window of the mouse uterus
    Hitomi Nakamura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    Am J Reprod Immunol 51:16-21. 2004
    ..However, temporal and spatial activation of NF-kappaB at implantation window is unknown...
  49. doi request reprint Early reduction of glucose uptake after cisplatin treatment is a marker of cisplatin sensitivity in ovarian cancer
    Tomomi Egawa-Takata
    Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari ku, Osaka, Japan
    Cancer Sci 101:2171-8. 2010
    ..Measuring glucose uptake might be useful as a rapid evaluation of cisplatin chemosensitivity in ovarian cancer patients...
  50. ncbi request reprint Differential expression and localization of decorin in human choriodecidual membrane during preterm and term pregnancy
    Kazuhide Ogita
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Suita, Japan
    Am J Reprod Immunol 51:204-10. 2004
    ..This study was aimed to isolate cDNAs for genes whose expression levels are dynamically regulated at the feto-maternal interface around parturition...
  51. ncbi request reprint Relationship between human tumor-associated antigen RCAS1 and gestational diabetes mellitus
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 58:440-6. 2007
    ....
  52. doi request reprint Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells
    Atsuko Wakabayashi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Gynecol Endocrinol 27:33-8. 2011
    ..In this study, we investigated the significant repressive effect of adiponectin on rat uterine leiomyoma ELT-3 cells proliferation...
  53. doi request reprint Chemotherapy for endometrial carcinoma (GOGO-EM1 study): TEC (paclitaxel, epirubicin, and carboplatin) is an effective remission-induction and adjuvant therapy
    Tomomi Egawa-Takata
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Cancer Chemother Pharmacol 68:1603-10. 2011
    ..TEC chemotherapy (paclitaxel, epirubicin, and carboplatin) has been suggested to have less toxicity; however, the optimal dosage has yet to be determined...
  54. doi request reprint Impact of histological subtype on survival of patients with surgically-treated stage IA2-IIB cervical cancer: adenocarcinoma versus squamous cell carcinoma
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
    Gynecol Oncol 127:114-20. 2012
    ..To evaluate the significance of adenocarcinoma (AC) compared with squamous cell carcinoma (SCC) with regard to the survival of surgically-treated early stage cervical cancer patients...
  55. ncbi request reprint Enormous cystic tumor of peritoneal psammocarcinoma exhibiting complete response to Cisplatin and cyclophosphamide after suboptimal cytoreduction: case report and review of the literature
    Ryoko Takahashi
    Department of Obstetrics and Gynecology, Toyonaka Municipal Hospital, Toyonaka, Japan
    Gynecol Obstet Invest 74:165-70. 2012
    ..Our case implies that CP therapy is a potential regimen of postoperative remission-induction therapy for suboptimally resected primary peritoneal psammocarcinoma...
  56. doi request reprint Prediction, based on resection margins, of long-term outcome of cervical intraepithelial neoplasia 3 treated by Shimodaira-Taniguchi conization
    Yukari Miyoshi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Arch Gynecol Obstet 285:1427-32. 2012
    ..The aim of the present study was to analyze the long-term outcome of cervical intraepithelial neoplasia 3 (CIN 3) after treatment with the Shimodaira-Taniguchi conization procedure, based on the status of the resection margins...
  57. doi request reprint Balloon tamponade during cesarean section is useful for severe post-partum hemorrhage due to placenta previa
    Takako Ishii
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    J Obstet Gynaecol Res 38:102-7. 2012
    ..The aim of this study was to evaluate the efficiency of intrauterine tamponade with a Sengstaken-Blakemore tube (SB-tube) for the treatment of severe post-partum hemorrhage in cases of placenta previa...
  58. doi request reprint Metastatic mucinous adenocarcinoma of the ovary is characterized by advanced patient age, small tumor size, and elevated serum CA125
    Makiko Maeda-Taniguchi
    Departments of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka, Japan
    Gynecol Obstet Invest 72:196-202. 2011
    ..The aim of the present study was to find a reliable method to discriminate primary from metastatic mucinous adenocarcinomas (MACs) of the ovary intraoperatively...
  59. doi request reprint Diagnostic performance of fluorodeoxyglucose positron emission tomography/magnetic resonance imaging fusion images of gynecological malignant tumors: comparison with positron emission tomography/computed tomography
    Kazuya Nakajo
    Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Jpn J Radiol 28:95-100. 2010
    ..We compared the diagnostic accuracy of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) and PET/magnetic resonance imaging (MRI) fusion images for gynecological malignancies...
  60. doi request reprint Up-regulation of alpha5-integrin by E-cadherin loss in hypoxia and its key role in the migration of extravillous trophoblast cells during early implantation
    Emi Arimoto-Ishida
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Endocrinology 150:4306-15. 2009
    ..This finding should help us reach a better understanding of the pathogenesis of critical gestational diseases, such as preeclampsia...
  61. doi request reprint Uterine cervical carcinoma: preoperative staging with 3.0-T MR imaging--comparison with 1.5-T MR imaging
    Masatoshi Hori
    Department of Radiology, Osaka University Graduate School of Medicine, D1, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Radiology 251:96-104. 2009
    ..To prospectively evaluate the efficacy of 3.0-T magnetic resonance (MR) imaging in the preoperative staging of cervical carcinoma compared with that at 1.5-T imaging, with surgery and pathologic analysis as the reference standards...
  62. ncbi request reprint Expression of fractalkine in the Fallopian tube and of CX3CR1 in sperm
    Qing Zhang
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
    Hum Reprod 19:409-14. 2004
    ..The objective of this study was 2-fold: to evaluate (i) the presence of fractalkine in the Fallopian tube and (ii) the existence of CX(3)CR1 (fractalkine receptor) in ejaculated sperm...
  63. ncbi request reprint Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure
    Hitomi Nakamura
    Division of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2, Yamadaoka, Suita, Osaka 5650871, Japan
    FEBS Lett 580:2717-22. 2006
    ..These conditions may mimic clinically unexplained infertility. Our results suggest that STAT-3 could be a useful target for diagnosis and therapy of human implantation failure...
  64. doi request reprint Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin
    Ayako Kim
    Department of Obstetrics and Gynaecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Cancer 125:2316-22. 2009
    ..These results demonstrate that Anx A4 confers chemoresistance in ovarian cancer cells in part by enhancing drug efflux. Thus, Anx A4 may represent a novel therapeutic target of chemoresistance in patients with ovarian CCC...
  65. doi request reprint Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Clin Cancer Res 14:7781-9. 2008
    ..We hypothesized that treatment with bevacizumab, a humanized recombinant anti-VEGF monoclonal antibody, could enhance antitumor response to cisplatin and prolong survival in a murine ovarian cancer model...
  66. doi request reprint Elevated white blood cell count at the time of recurrence diagnosis is an indicator of short survival in patients with recurrent cervical cancer
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Int J Gynecol Cancer 22:1545-51. 2012
    ..The aim of this study was to investigate the prognostic significance of elevated white blood cell (WBC) count at the time of the diagnosis of cervical cancer recurrence...
  67. ncbi request reprint Salvage chemotherapy using gemcitabine for taxane/platinum-resistant recurrent ovarian cancer: a single institutional experience
    Kiyoshi Yoshino
    Department of Obstetrics and Gynecology, Osaka University, Graduate School of Medicine, Suita, Osaka, Japan
    Anticancer Res 32:4029-33. 2012
    ..The purpose of this study was to report on the safety and efficacy of gemcitabine used as salvage chemotherapy for ovarian cancer...
  68. doi request reprint Usefulness of computed tomography in predicting cytoreductive surgical outcomes for ovarian cancer
    Kazuko Fujwara
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Arch Gynecol Obstet 284:1501-7. 2011
    ..The objective of this study was to identify features of preoperative computed tomography (CT) scans that can best predict outcomes of primary cytoreductive surgery in ovarian cancer patients...
  69. ncbi request reprint Effects of 4-hydroxy-2-nonenal, a marker of oxidative stress, on the cyclooxygenase-2 of human placenta in chorioamnionitis
    Kumiko Temma
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
    Mol Hum Reprod 10:167-71. 2004
    ..In addition, PGE(2) was also released into the medium in a time-dependent fashion. These findings suggest that HNE-modified proteins, which were increased in the placenta with CAM, play an important role in preterm labour...
  70. ncbi request reprint Disease-free interval after primary treatment predicts prognosis of recurrent endometrial carcinoma
    Yutaka Ueda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Anticancer Res 30:4347-52. 2010
    ..The aim of this study was to determine if the disease-free interval after initial surgical resection has any useful prognostic value for recurrent endometrial carcinoma patients...
  71. doi request reprint Nicotine suppresses interleukin-6 production from vascular endothelial cells: a possible therapeutic role of nicotine for preeclampsia
    Namuxila Sharentuya
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Reprod Sci 17:556-63. 2010
    ..Nicotine inhibited inflammatory reaction through NF-kB suppression in vitro model of maternal vascular endothelium, and this effect may be one of the explanations for the reduced risk of preeclampsia in smokers...
  72. doi request reprint The activity of trabectedin as a single agent or in combination with everolimus for clear cell carcinoma of the ovary
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Clin Cancer Res 17:4462-73. 2011
    ..The objective of this study was to evaluate the antitumor efficacy of trabectedin in clear cell carcinoma (CCC) of the ovary, which is regarded as an aggressive, chemoresistant, histologic subtype...
  73. doi request reprint Pretreatment leukocytosis is an indicator of poor prognosis in patients with cervical cancer
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Gynecol Oncol 122:25-32. 2011
    ..The aim of this study was to investigate the prognostic value of pretreatment leukocytosis in patients with cervical cancer in relation to well-established conventional risk factors...
  74. doi request reprint Maternal blood serum and plasma human tumor-associated antigen RCAS1 during the course of uncomplicated pregnancies: a prospective study
    Ekaterine Tskitishvili
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan
    Am J Reprod Immunol 64:218-24. 2010
    ..we aimed to investigate the expression of the tumor-associated RCAS1 protein in maternal blood of uncomplicated pregnancies...
  75. ncbi request reprint Prognostic significance of CUB domain containing protein expression in endometrioid adenocarcinoma
    Suhana Mamat
    Department of Pathology, Osaka University Graduate School of Medicine, Suita 565 0871, Japan
    Oncol Rep 23:1221-7. 2010
    ..As compared to cancer cells, normal endometrium continuously expressed CDCP1. These suggested that the attitude of CDCP1 in cancers of lung and endometrium was different. Different role of CDCP1 by tissues and cancers is discussed...
  76. doi request reprint Peripheral quantitative computed tomography is useful to monitor response to alendronate therapy in postmenopausal women
    Kenjiro Sawada
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Bone Miner Metab 27:175-81. 2009
    ..Collectively, our preliminary clinical trial showed that pQCT might be useful to monitor response to alendronate therapy, especially at the radius, and it might explain why alendronate prevents Colles' fracture...
  77. doi request reprint Frequent inactivation of RUNX3 in endometrial carcinoma
    Tatsuo Yoshizaki
    Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Suita, Osaka, Japan
    Gynecol Oncol 110:439-44. 2008
    ..Our objective was to determine whether RUNX3 tumor suppressor is inactivated in endometrial carcinoma...
  78. ncbi request reprint Highly efficient and minimally invasive in-vivo gene transfer to the mouse uterus using haemagglutinating virus of Japan (HVJ) envelope vector
    Hitomi Nakamura
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Mol Hum Reprod 9:603-9. 2003
    ..We believe that this procedure should be widely applicable for investigations of reproductive physiology as well as for methods of local gene therapy in the uterus...
  79. doi request reprint Calcineurin/NFAT pathway: a novel regulator of parturition
    Chisa Tabata
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 5650871, Japan
    Am J Reprod Immunol 62:44-50. 2009
    ..However, we found OTR-deficient (OTRKO) mice are fertile and deliver at term without birth defects, thus alternative pathways inducing parturition can be hypothesized...
  80. ncbi request reprint Fractalkine (FRK) levels in amniotic fluid and its production during pregnancy
    Koichiro Shimoya
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Japan
    Mol Hum Reprod 9:97-101. 2003
    ..CX(3)CR1-positive cells had migrated into the amniotic fluid and the amnion. The present findings suggest that fractalkine found in amniotic fluid may contribute to the immunodefence mechanism during pregnancy...
  81. doi request reprint Pseudomyxoma peritonei originating from colorectal cancer during pregnancy
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 37:254-8. 2011
    ....
  82. ncbi request reprint Tension-free vaginal tape procedure with manual-tapping method: a potentially useful technique
    Koji Matsuo
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 31:247-51. 2005
    ..We investigate a procedure to adjust the level of suspension of the mid-urethra using tension-free vaginal tape (TVT) under general anesthesia at the time of POP repair surgery...
  83. doi request reprint Relationship between metabolic syndrome and uterine leiomyomas: a case-control study
    Takashi Takeda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Gynecol Obstet Invest 66:14-7. 2008
    ..Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigated whether fibroids are associated with some criteria of the metabolic syndrome...
  84. ncbi request reprint Impaired delivery outcomes in pregnancies following myomectomy compared to myoma-complicated pregnancies
    Yukiko Kinugasa-Taniguchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Reprod Med 56:142-8. 2011
    ..To compare obstetric and delivery outcomes between myoma-complicated pregnancies and pregnancies that follow myomectomy...
  85. ncbi request reprint Rapid detection of trisomy 21 by gene dosage analysis using quantitative real-time polymerase chain reaction
    Tomoko Tsujie
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    J Obstet Gynaecol Res 32:368-72. 2006
    ..Rapid detection of fetal aneuploidy helps inform a mother's choice about the course of her pregnancy. Obtaining results by fluorescent in situ hybridization (FISH) requires more than 24 h, and thus a more rapid method is needed...
  86. doi request reprint Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in an in vitro model of preeclamptic vascular endothelium: a possible therapeutic role of nicotinic acetylcholine receptor (nAChR) agonists for preeclampsia
    Kazuya Mimura
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Am J Obstet Gynecol 202:464.e1-6. 2010
    ..In this study we tested the hypothesis that nicotine restores proangiogenic functions to endothelial cells pretreated with soluble fms-like tyrosine kinase 1 and/or soluble endoglin...
  87. ncbi request reprint Elevated expression of N-acetylglucosaminyltransferase V in first trimester human placenta
    Mari Tomiie
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 330:999-1004. 2005
    ..These results suggest that GnT-V would contribute to placentation in the early phase of pregnancy, possibly regulating the process of invasion of trophoblast cells...
  88. ncbi request reprint Geranylgeranylacetone inhibits ovarian cancer progression in vitro and in vivo
    Kae Hashimoto
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Biochem Biophys Res Commun 356:72-7. 2007
    ..In conclusion, this is the first report that GGA inhibited ovarian cancer progression and the anti-tumor effect by GGA is, at least in part, derived not only from the suppression of Rho activation but also Ras-MAPK activation...
  89. ncbi request reprint Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells
    Kae Hashimoto
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Biochem Biophys Res Commun 354:478-84. 2007
    ..In conclusion, the in vivo anti-tumor effect of alendronate might be derived, at least in part, from its direct antiangiogenic effects on intra-tumor endothelial cells by inhibiting Rho geranylgeranylation...
  90. doi request reprint Effectiveness of the herbal medicine daikenchuto for radiation-induced enteritis
    Takashi Takeda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Altern Complement Med 14:753-5. 2008
    ..This report describes a patient with radiation-induced enteritis whose clinical symptoms were much improved by treatment with DKT...
  91. ncbi request reprint Surgical reinforcement of support for the vagina in pelvic organ prolapse: concurrent iliococcygeus fascia colpopexy (Inmon technique)
    Masayasu Koyama
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan
    Int Urogynecol J Pelvic Floor Dysfunct 16:197-202. 2005
    ..These results suggest that iliococcygeus fascia colpopexy is reasonably safe and strengthens not only the attachment of the upper part of the vagina but also that of the anterolateral vaginal wall...
  92. doi request reprint Use of monoclonal antibodies in the treatment of ovarian cancer
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Curr Opin Obstet Gynecol 22:3-8. 2010
    ..One of the promising approaches that may improve patient outcome is the use of monoclonal antibodies (mAbs)...
  93. ncbi request reprint Treatment of ovarian cancer by monoclonal antibodies
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Discov Med 9:197-203. 2010
    ..As the preclinical results of mAb's therapeutic effects on ovarian cancer have been encouraging, further investigations are needed to establish a more effective, specific, and less toxic treatment strategy for this malignancy...
  94. doi request reprint MR imaging of endometrial carcinoma for preoperative staging at 3.0 T: comparison with imaging at 1.5 T
    Masatoshi Hori
    Department of Radiology, Osaka University Graduate School of Medicine, Osaka, Japan
    J Magn Reson Imaging 30:621-30. 2009
    ..To prospectively compare magnetic resonance imaging (MRI) at 3.0 T and 1.5 T in the same patients for preoperative evaluation of endometrial carcinoma...
  95. pmc mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Clin Cancer Res 15:5404-13. 2009
    ..This study aimed to examine the role of mTOR as a therapeutic target in clear cell carcinoma of the ovary, which is regarded as an aggressive, chemoresistant histologic subtype...
  96. doi request reprint Cervical insufficiency following cesarean delivery after prolonged second stage of labor: experiences of two cases
    Shinsuke Koyama
    Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan
    J Obstet Gynaecol Res 36:411-3. 2010
    ..Our report highlights the need to alert obstetricians to take more care with their cesarean section technique...
  97. doi request reprint Prognostic factors for survival in patients with recurrent cervical cancer previously treated with radiotherapy
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan
    Int J Gynecol Cancer 20:834-40. 2010
    ..The aim of this study was to identify the prognostic factors and to establish a model for the prediction of life expectancy in patients with recurrent cervical cancer that had previously been treated with radiotherapy...
  98. doi request reprint Elevated level of plasma vascular endothelial growth factor after gonadotropin-releasing hormone agonist treatment for leiomyomata
    Takashi Takeda
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Japan
    Gynecol Endocrinol 24:724-6. 2008
    ..In this study, we investigated the plasma level of vascular endothelial growth factor (VEGF) in uterine leiomyoma patients with or without GnRH-a pretreatment...
  99. doi request reprint The activity of carboplatin and paclitaxel for recurrent cervical cancer after definitive radiotherapy
    Seiji Mabuchi
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Gynecol Oncol 113:200-4. 2009
    ..The aim of this study was to evaluate the efficacy of paclitaxel-carboplatin (TC) for recurrent cervical cancer after definitive radiotherapy and to compare the results with non-taxane containing platinum-based chemotherapies (NTP)...
  100. ncbi request reprint Dual repressive effect of angiotensin II-type 1 receptor blocker telmisartan on angiotensin II-induced and estradiol-induced uterine leiomyoma cell proliferation
    Aki Isobe
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Hum Reprod 23:440-6. 2008
    ..Elevated blood pressure has an independent, positive association with risk for clinically detected uterine leiomyoma. Angiotensin II (Ang II) is a key biological peptide in the renin-angiotensin system that regulates blood pressure...
  101. ncbi request reprint The expression of secretory leukocyte protease inhibitor (SLPI) in the fallopian tube: SLPI protects the acrosome reaction of sperm from inhibitory effects of elastase
    Yukinobu Ota
    Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita City, Japan
    Hum Reprod 17:2517-22. 2002
    ..The objective of the study was 2-fold, to evaluate (i) the presence of SLPI in the Fallopian tube, and (ii) the effect of SLPI on the acrosome reaction of sperm...