Research Topics

Genomes and Genes

Species

Satoru Kawamura

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. Tomizuka J, Tachibanaki S, Kawamura S. Phosphorylation-independent suppression of light-activated visual pigment by arrestin in carp rods and cones. J Biol Chem. 2015;290:9399-411 pubmed publisher
    ..Our results suggested a novel mechanism of arrestin effect on the suppression of the R* activity in both rods and cones. ..
  2. Kawakami N, Kawamura S. Difference in the gain in the phototransduction cascade between rods and cones in carp. J Neurosci. 2014;34:14682-6 pubmed publisher
  3. Yamaoka H, Tachibanaki S, Kawamura S. Dephosphorylation during bleach and regeneration of visual pigment in carp rod and cone membranes. J Biol Chem. 2015;290:24381-90 pubmed publisher
    ..The results also suggest that, under bright light, some of the regenerated visual pigment remains phosphorylated to reduce the light sensitivity in cones. ..
  4. Kawamura S, Tachibanaki S. Rod and cone photoreceptors: molecular basis of the difference in their physiology. Comp Biochem Physiol A Mol Integr Physiol. 2008;150:369-77 pubmed publisher
    ..Based on these findings, we speculated a possible mechanism of evolution of rods that diverged from cones. ..
  5. Sato S, Miyazono S, Tachibanaki S, Kawamura S. RDH13L, an enzyme responsible for the aldehyde-alcohol redox coupling reaction (AL-OL coupling reaction) to supply 11-cis retinal in the carp cone retinoid cycle. J Biol Chem. 2015;290:2983-92 pubmed publisher
    ..This dual mechanism of 11-cis retinal synthesis attained by carp RDH13L and mouse RDH14 probably contribute to effective pigment regeneration in cones that function in the light. ..