Affiliation: Osaka University
Ito A, Watabe K, Koma Y, Kitamura Y. An attempt to isolate genes responsible for spontaneous and experimental metastasis in the mouse model. Histol Histopathol. 2002;17:951-9 pubmed publisher
..Moreover, similar roles were expected for the genes in the process by which human melanoma cells metastasize. ..
Ito A, Okada M, Uchino K, Wakayama T, Koma Y, Iseki S, et al
. Expression of the TSLC1 adhesion molecule in pulmonary epithelium and its down-regulation in pulmonary adenocarcinoma other than bronchioloalveolar carcinoma. Lab Invest. 2003;83:1175-83 pubmed
..Thus, the present results not only support the hypothesis that TSLC1 is a tumor suppressor of NSCLC but also suggest that preserved integrity of TSLC1 may contribute to less invasive phenotypes of lepidic growth tumor cells. ..
Ito A, Koma Y, Watabe K, Nagano T, Endo Y, Nojima H, et al
. A truncated isoform of the protein phosphatase 2A B56gamma regulatory subunit may promote genetic instability and cause tumor progression. Am J Pathol. 2003;162:81-91 pubmed
..These observations support the notion that mechanisms promoting the genetic instability of tumors could also aid tumor progression from the nonmetastatic to the metastatic state. ..
Ito A, Koma Y, Sohda M, Watabe K, Nagano T, Misumi Y, et al
. Localization of the PP2A B56gamma regulatory subunit at the Golgi complex: possible role in vesicle transport and migration. Am J Pathol. 2003;162:479-89 pubmed