M Inaba

Summary

Affiliation: Osaka City University
Country: Japan

Publications

  1. doi request reprint Association between glycemic control and morning blood pressure surge with vascular endothelial dysfunction in type 2 diabetic patients
    Koichiro Yoda
    Corresponding author Masaaki Inaba
    Diabetes Care 37:644-50. 2014
  2. ncbi request reprint Increased active PTH(1-84) fraction as a predictor of poor mortality in male hemodialysis patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Internal Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Osteoporos Int 24:2863-70. 2013
  3. doi request reprint Impact of atherosclerosis on the relationship of glycemic control and mortality in diabetic patients on hemodialysis
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Kyoto, Japan
    Clin Nephrol 78:273-80. 2012
  4. doi request reprint Disappearance of association in diabetic patients on hemodialysis between anemia and mortality risk: the Japan dialysis outcomes and practice pattern study
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephron Clin Pract 120:c91-c100. 2012
  5. ncbi request reprint Role of fibroblast growth factor-23 in peripheral vascular calcification in non-diabetic and diabetic hemodialysis patients
    M Inaba
    Department of Endocrinology, Metabolism, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Osteoporos Int 17:1506-13. 2006
  6. ncbi request reprint Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Am Soc Nephrol 18:896-903. 2007
  7. ncbi request reprint Significance of serum CrossLaps as a predictor of changes in bone mineral density during estrogen replacement therapy; comparison with serum carboxyterminal telopeptide of type I collagen and urinary deoxypyridinoline
    Reiko Okabe
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585, Osaka, Japan
    J Bone Miner Metab 22:127-31. 2004
  8. ncbi request reprint Independent association of increased trunk fat with increased arterial stiffening in postmenopausal patients with rheumatoid arthritis
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Rheumatol 34:290-5. 2007
  9. ncbi request reprint Increased stiffness in common carotid artery in hyperthyroid Graves' disease patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Biomed Pharmacother 56:241-6. 2002
  10. ncbi request reprint Impaired secretion of parathyroid hormone, but not refractoriness of osteoblast, is a major mechanism of low bone turnover in hemodialyzed patients with diabetes mellitus
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 39:1261-9. 2002

Collaborators

Detail Information

Publications118 found, 100 shown here

  1. doi request reprint Association between glycemic control and morning blood pressure surge with vascular endothelial dysfunction in type 2 diabetic patients
    Koichiro Yoda
    Corresponding author Masaaki Inaba
    Diabetes Care 37:644-50. 2014
    ..The current study examined the association between glycemic control and MBPS, and the involvement of MBPS in the development of vascular dysfunction in T2DM patients...
  2. ncbi request reprint Increased active PTH(1-84) fraction as a predictor of poor mortality in male hemodialysis patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Internal Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Osteoporos Int 24:2863-70. 2013
    ..The present study demonstrated that higher PTH(1-84)/intact PTH ratio, but not serum PTH(1-84) and intact PTH, predicted higher all-cause mortality in 177 male hemodialysis patients...
  3. doi request reprint Impact of atherosclerosis on the relationship of glycemic control and mortality in diabetic patients on hemodialysis
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Kyoto, Japan
    Clin Nephrol 78:273-80. 2012
    ..The impact of preexisting cardiovascular disease (CVD) on glycemic control-improved survival in hemodialysis patients with diabetes mellitus (DM) was investigated. Glycoalbumin (GA) was used as a glycemic marker...
  4. doi request reprint Disappearance of association in diabetic patients on hemodialysis between anemia and mortality risk: the Japan dialysis outcomes and practice pattern study
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Nephron Clin Pract 120:c91-c100. 2012
    ..583). In conclusion, these results suggested that the association between anemia and higher mortality disappeared in DM hemodialysis patients, in contrast with non-DM counterparts...
  5. ncbi request reprint Role of fibroblast growth factor-23 in peripheral vascular calcification in non-diabetic and diabetic hemodialysis patients
    M Inaba
    Department of Endocrinology, Metabolism, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Osteoporos Int 17:1506-13. 2006
    ....
  6. ncbi request reprint Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    J Am Soc Nephrol 18:896-903. 2007
    ....
  7. ncbi request reprint Significance of serum CrossLaps as a predictor of changes in bone mineral density during estrogen replacement therapy; comparison with serum carboxyterminal telopeptide of type I collagen and urinary deoxypyridinoline
    Reiko Okabe
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585, Osaka, Japan
    J Bone Miner Metab 22:127-31. 2004
    ..In conclusion, the findings suggest that the Elecsys Beta-CrossLaps/serum assay provides a sensitive, and thus useful, tool for assessing bone resorption state in Japanese patients...
  8. ncbi request reprint Independent association of increased trunk fat with increased arterial stiffening in postmenopausal patients with rheumatoid arthritis
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Rheumatol 34:290-5. 2007
    ..The current study examined the possible involvement of trunk fat in increased arterial stiffening in postmenopausal patients with RA...
  9. ncbi request reprint Increased stiffness in common carotid artery in hyperthyroid Graves' disease patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Biomed Pharmacother 56:241-6. 2002
    ..In summary, the significant increase in stiffness beta in the hyperthyroid state may reflect the harmful effect of hyperthyroidism on the arterial wall, which may in turn result from increased stroke volume...
  10. ncbi request reprint Impaired secretion of parathyroid hormone, but not refractoriness of osteoblast, is a major mechanism of low bone turnover in hemodialyzed patients with diabetes mellitus
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 39:1261-9. 2002
    ..In conclusion, our findings suggest that impaired PTH secretion, but not refractoriness of osteoblasts to PTH, may be responsible for the low bone turnover in hemodialyzed patients with diabetes...
  11. ncbi request reprint Impaired secretion of parathyroid hormone is coherent to diabetic hemodialyzed patients
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Am J Kidney Dis 38:S139-42. 2001
    ....
  12. ncbi request reprint Positive correlation of serum bio-intact PTH(1-84) but not intact PTH with parathyroid gland size in hemodialysis patients
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Biomed Pharmacother 60:62-5. 2006
    ..In conclusion, serum Bio-PTH assay could provide a better assay than I-PTH assay to estimate parathyroid function in HD patients, due mainly to its exclusive correlation with parathyroid gland size...
  13. ncbi request reprint Preferential reductions of paraarticular trabecular bone component in ultradistal radius and of calcaneus ultrasonography in early-stage rheumatoid arthritis
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, 545 8585 Osaka, Japan
    Osteoporos Int 14:683-7. 2003
    ....
  14. ncbi request reprint Significance of Bio-intact PTH(1-84) assay in hemodialysis patients
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585 Osaka, Japan
    Osteoporos Int 16:517-25. 2005
    ....
  15. ncbi request reprint Technical and clinical characterization of the Bio-PTH (1-84) immunochemiluminometric assay and comparison with a second-generation assay for parathyroid hormone
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Chem 50:385-90. 2004
    ..We investigated the technical performance and clinical significance of this new assay...
  16. ncbi request reprint Secondary osteoporosis: thyrotoxicosis, rheumatoid arthritis, and diabetes mellitus
    Masaaki Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585, Osaka, Japan
    J Bone Miner Metab 22:287-92. 2004
  17. ncbi request reprint Increased incidence of vertebral fracture in older female hemodialyzed patients with type 2 diabetes mellitus
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, 545 8585, Osaka, Japan
    Calcif Tissue Int 76:256-60. 2005
    ....
  18. ncbi request reprint Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice
    T Kushida
    First Department of Pathology, Transplantation Center, Kansai Medical University, Moriguchi City, Osaka, Japan
    Blood 97:3292-9. 2001
    ..This strategy would therefore be suitable for human therapy...
  19. doi request reprint Significant inverse relationship between serum undercarboxylated osteocalcin and glycemic control in maintenance hemodialysis patients
    S Okuno
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Osteoporos Int 24:605-12. 2013
    ....
  20. ncbi request reprint Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Kidney Int 55:1019-27. 1999
    ..In patients with chronic renal failure (CRF), abnormalities in vitamin D metabolism are known to be present, and several factors could contribute to the abnormalities...
  21. ncbi request reprint Serum N-terminal midfragment vs. intact osteocalcin immunoradiometric assay as markers for bone turnover and bone loss in hemodialysis patients
    K Nagasue
    Shirasagi Hospital, 7 11 23, Kumata, Higashisumiyoshi ku, Osaka, Japan
    Biomed Pharmacother 57:98-104. 2003
    ..It may, therefore, prove more reliable than iOC assay for evaluating bone turnover, and thus for reflecting bone loss, in HD patients...
  22. doi request reprint Allogeneic intra-BM-BMT plus adult thymus transplantation from same donor has benefits for long-term survival even after sublethal irradiation or low-dose BM cell injection
    T Nishida
    Department of Pathology, Kansai Medical University, Moriguchi, Osaka, Japan
    Bone Marrow Transplant 43:829-37. 2009
    ..These results suggest that IBM-BMT plus ATT is effective in reconstituting the recipients with donor-derived cells even after SubLI or LDBMCI...
  23. ncbi request reprint Impaired endothelium-dependent vascular responses of retinal and intrarenal arteries in patients with type 2 diabetes
    T Kawagishi
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Arterioscler Thromb Vasc Biol 19:2509-16. 1999
    ....
  24. doi request reprint Reduction of whole PTH/intact PTH ratio as a predictor of bone metabolism in cinacalcet treatment of hemodialysis patients with secondary hyperparathyroidism
    M Kurajoh
    Department of Metabolism, Endocrinology and Molecular Medicine, Internal Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Osteoporos Int 22:923-30. 2011
    ..Changes in W-PTH/I-PTH ratio significantly correlated and predicted changes in bone marker...
  25. ncbi request reprint Renal insufficiency accelerates atherosclerosis in patients with type 2 diabetes mellitus
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S186-90. 2001
    ....
  26. ncbi request reprint Serum adiponectin and bone mineral density in male hemodialysis patients
    S Okuno
    Kidney Center, Shirasagi Hospital, 7 11 23, Kumata, Higashisumiyoshi ku, Osaka, 546 0002, Japan
    Osteoporos Int 23:2027-35. 2012
    ..There was a significant positive correlation between serum adiponectin and serum NTX. Thus, adiponectin may play a role in mineral and bone disorder in chronic kidney disease stage 5 dialysis (CKD 5D) patients...
  27. ncbi request reprint Clinical evaluation of the Elecsys beta-CrossLaps serum assay, a new assay for degradation products of type I collagen C-tlopeptides
    R Okabe
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan
    Clin Chem 47:1410-4. 2001
    ..9% +/- 3.9% and 16.9% +/- 4.6%, respectively). CONCLUSIONS: The Elecsys beta-CrossLaps serum assay provides a potentially useful tool for assessing bone resorption state, including its response to estrogen replacement therapy...
  28. ncbi request reprint Atherogenic lipoprotein changes in diabetic nephropathy
    T Shoji
    Second Department of Internal Medicine, Osaka City University Medical School, 1 4 3 Asahi machi, Osaka 545 8585, Abeno Ku, Japan
    Atherosclerosis 156:425-33. 2001
    ..These lipoprotein alterations may contribute to an increased cardiovascular risk in diabetic nephropathy, especially in diabetic renal failure...
  29. ncbi request reprint Increasing body fat mass in the first year of hemodialysis
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan Shirasagi Hospital Kidney Center, Osaka, Japan
    J Am Soc Nephrol 12:1921-6. 2001
    ..More general, dual x-ray absorptiometry assessment of body fat mass was found to be useful for evaluating the nutritional status of hemodialysis patients...
  30. doi request reprint Glycemic control and survival of diabetic hemodialysis patients--importance of lower hemoglobin A1C levels
    E Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetes Res Clin Pract 83:320-6. 2009
    ..The significance of hemoglobin A1C (HbA1C) on the survival of diabetic hemodialysis patients still remains controversial. We investigated the impact of HbA1C on the survival...
  31. ncbi request reprint Differential regulation of human blood dendritic cell subsets by IFNs
    T Ito
    First Department of Internal Medicine, Kansai Medical University, Osaka, Japan
    J Immunol 166:2961-9. 2001
    ..The IL-3-primed CD11c(-) DCs activated T cells to produce IL-10, IFN-gamma, and IL-4. Thus, CD11c(+) and CD11c(-) DC subsets play distinct roles in the cytokine network, especially their responses to IFNs...
  32. ncbi request reprint Changes in body fat mass in male hemodialysis patients: a comparison between diabetics and nondiabetics
    S Okuno
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Am J Kidney Dis 38:S208-11. 2001
    ..Dual x-ray absorptiometry assessment of fat mass changes is suggested as a useful method to examine clinically the nutritional status of hemodialysis patients...
  33. ncbi request reprint Different risk factors for peripheral vascular calcification between diabetic and non-diabetic haemodialysis patients--importance of glycaemic control
    E Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetologia 45:1446-8. 2002
    ..We compared factors affecting peripheral vascular calcification between haemodialysis patients with and without diabetes...
  34. doi request reprint Association of increased active PTH(1-84) fraction with decreased GFR and serum Ca in predialysis CRF patients: modulation by serum 25-OH-D
    M Kurajoh
    Department of Metabolism, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, 545 8585, Japan
    Osteoporos Int 19:709-16. 2008
    ..As the serum calcium and glomerular filtration rate decreased, the proportion of active PTH(1-84) molecules in PTH immunoreactivity increased in serum from predialysis uremic patients, particularly those with vitamin D insufficiency...
  35. ncbi request reprint Paradox of risk factors for cardiovascular mortality in uremia: is a higher cholesterol level better for atherosclerosis in uremia?
    Y Nishizawa
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S4-7. 2001
    ..Further studies are needed to show the differential effects of a risk factor on event rate and fatality rate. Patients with ESRD would have a better chance of living longer by better management of the two categories of risk factors...
  36. ncbi request reprint Effect of cinacalcet on bone mineral density of the radius in hemodialysis patients with secondary hyperparathyroidism
    E Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, Japan
    Clin Nephrol 76:259-65. 2011
    ..It is not well known whether bone mineral density (BMD) of hemodialysis patients with secondary hyperparathyroidism is altered after cinacalcet treatment...
  37. ncbi request reprint Crucial role of donor-derived stromal cells in successful treatment for intractable autoimmune diseases in mrl/lpr mice by bmt via portal vein
    T Kushida
    First Department of Pathology, Transplantation Center, Kansai Medical University, Moriguchi City, Osaka, Japan
    Stem Cells 19:226-35. 2001
    ..This new strategy to facilitate the early recovery of hemopoiesis would therefore be of great advantage in human application...
  38. pmc Prevention of graft-versus-host disease by intrabone marrow injection of donor T cells: involvement of bone marrow stromal cells
    T Miyake
    First Department of Pathology, and Department of Surgery, Kansai Medical University, Osaka, Japan
    Clin Exp Immunol 152:153-62. 2008
    ..v.-DLI. Thus, the prevention of GVHD observed in the recipients of IBM-BMT + IBM-DLI was attributable to the increased production of immunosuppressive cytokines from BMSCs after interaction with host reactive T cells (in DLI)...
  39. ncbi request reprint Poor muscle quality rather than reduced lean body mass is responsible for the lower serum creatinine level in hemodialysis patients with diabetes mellitus
    M Inaba
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Nephrol 74:266-72. 2010
    ..The factors associated with this finding have not been determined...
  40. ncbi request reprint A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells
    T Ito
    First Department of Internal Medicine, First Department of Pathology, Kansai Medical University, Osaka, Japan
    J Immunol 163:1409-19. 1999
    ..Furthermore, CD14+ monocytes only expressed E-cadherin, but lacked the other LC markers after culture in these cytokines. Therefore, CD1a+/CD11c+ DCs are the direct precursors of LCs in peripheral blood...
  41. pmc Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells
    M Inaba
    Department of Pathology, Kansai Medical University, Osaka, Japan
    J Exp Med 173:549-59. 1991
    ..Therefore, different types of bone marrow-derived APC have different capacities for inducing tolerance, and the active cell types (dendritic cells and CD5+ thymic B cells) can act by distinct mechanisms...
  42. ncbi request reprint Relations between ACE gene and ecNOS gene polymorphisms and resistive index in type 2 diabetic patients with nephropathy
    H Taniwaki
    Second Department of Internal Medicine, Osaka City University Medical School, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetes Care 24:1653-60. 2001
    ..In order to assess the effect of the gene polymorphism of both ACE and ecNOS on renal hemodynamic abnormality, we examined 155 Japanese patients with type 2 diabetes with various stages of nephropathy...
  43. ncbi request reprint Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients
    E Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Clin Nephrol 68:222-7. 2007
    ..The aim of the present study was to examine the association between serum magnesium levels and vascular calcification in hemodialysis patients...
  44. ncbi request reprint Prevention of accelerated presbycusis by bone marrow transplantation in senescence-accelerated mice
    H Iwai
    Department of Otorhinolaryngology, Kansai Medical University, Moriguchi, Osaka, Japan
    Bone Marrow Transplant 28:323-8. 2001
    ....
  45. pmc The Wistar Bonn Kobori rat, a unique animal model for autoimmune pancreatitis with extrapancreatic exocrinopathy
    Y Sakaguchi
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Clin Exp Immunol 152:1-12. 2008
    ..We also show that these autoimmune diseases can be prevented by a newly devised strategy of bone marrow transplantation (BMT) in which bone marrow cells are injected directly into the bone marrow cavity: intrabone marrow-BMT...
  46. pmc Treatment of autoimmune diseases in MRL/lpr mice by allogenic bone marrow transplantation plus adult thymus transplantation
    N Hosaka
    First Department of Pathology, Kansai Medical University, Moriguchi, Osaka, Japan
    Clin Exp Immunol 147:555-63. 2007
    ..Finally, the autoimmune diseases in MRL/lpr mice could be cured by BMT with TT. These results indicate that the combination of BMT plus TT can overcome the chimeric resistance and treat the autoimmune diseases in MRL/lpr mice...
  47. ncbi request reprint Correlation between peritoneal mesothelial cell cytology and peritoneal histopathology with respect to prognosis in patients on continuous ambulatory peritoneal dialysis
    T Izumotani
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Nephron 89:43-9. 2001
    ....
  48. ncbi request reprint Risk factors for asymptomatic atherosclerosis in Japanese type 2 diabetic patients without diabetic microvascular complications
    K Goya
    Department of Molecular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Metabolism 52:1302-6. 2003
    ..Conventional risk factors and diabetes treatment are independently associated with atherosclerosis of the carotid arteries in these patients...
  49. ncbi request reprint A Hodgkin's disease cell line, KM-H2, shows biphenotypic features of dendritic cells and B cells
    K Uehira
    First Department of Internal Medicine, Kansai Medical University, Osaka, Japan
    Int J Hematol 73:236-44. 2001
    ..These findings lead to a hypothesis that KM-H2 cells originated from the cells that had differentiated through the possible common DC-B-cell progenitors along the newly proposed pathway...
  50. ncbi request reprint Changes in markers, receptors and adhesion molecules expressed on murine hemopoietic stem cells after a single injection of 5-fluorouracil
    N Nishio
    First Department of Pathology, Kansai Medical University, Osaka, Japan
    Stem Cells 14:584-91. 1996
    ..However, there is no change in the expression of adhesion molecules (VLA-4, LFA-1 and CD44) on the P-HSC...
  51. ncbi request reprint Femoral artery wall thickness and stiffness in evaluation of peripheral vascular disease in type 2 diabetes mellitus
    H Taniwaki
    Second Department of Internal Medicine, Osaka City University Medical School, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan
    Atherosclerosis 158:207-14. 2001
    ..These data suggest that stiffening of arterial wall has a significant impact on PVD manifestations, particularly on the leg symptoms, in patients with type 2 diabetes...
  52. ncbi request reprint Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus
    S Nakatani
    Departments of Metabolism, Endocrinology, and Molecular Medicine Osaka City University Graduate School of Medicine, Osaka, Japan Departments of Nephrology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Diabetes Res Clin Pract 105:40-6. 2014
    ..The renin-angiotensin system (RAS) plays an important role in the pathogenesis of diabetic nephropathy. The aim of the present study was to investigate intrarenal RAS activity in patients with type 2 diabetes (T2DM)...
  53. ncbi request reprint Atherogenic lipoproteins in end-stage renal disease
    T Shoji
    Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan
    Am J Kidney Dis 38:S30-3. 2001
    ..The effect of lipid-lowering therapy on cardiovascular mortality in ESRD, however, awaits the results of ongoing prospective trials...
  54. ncbi request reprint Rare somatic inactivation of the multiple endocrine neoplasia type 1 gene in secondary hyperparathyroidism of uremia
    H Tahara
    Department of Internal Medicine, Osaka City University Graduate School of Medicine, Japan
    J Clin Endocrinol Metab 85:4113-7. 2000
    ..These observations indicate that somatic inactivation of the MEN1 gene contributes to the pathogenesis of uremia-associated parathyroid tumors, but its role in this disease appears to be very limited...
  55. pmc Successful pancreatic allografts in combination with bone marrow transplantation in mice
    H Iwai
    1st Department of Pathology, Kansai Medical College, Osaka, Japan
    Immunology 62:457-62. 1987
    ..These findings suggest that pancreatic allografts combined with bone marrow transplantation may become a viable strategy for the treatment of patients with diabetes or patients who have undergone pancreatectomy...
  56. ncbi request reprint Modulation by cAMP of 1alpha,25-dihydroxyvitamin D3 sensitivity of murine erythroleukemia cells
    M Waki
    Division of Metabolism, Department of Biochemistry, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan
    Arch Biochem Biophys 391:265-70. 2001
    ....
  57. ncbi request reprint Treatment of streptozotocin-induced diabetes mellitus in mice by intra-bone marrow bone marrow transplantation plus portal vein injection of beta cells induced from bone marrow cells
    M Li
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Int J Hematol 86:438-45. 2007
    ..Hyperglycemia was normalized by 5 days after the treatment and remained normal for more than 45 days. This strategy might be applicable to patients with type I diabetes mellitus...
  58. ncbi request reprint Significant association of poor glycemic control with increased resistance in efferent arterioles--study of inulin and para-aminohippuric acid clearance in humans
    A Tsuda
    Department of Endocrinology, Metabolism and Molecular Medicine, Japan
    Diabetes Res Clin Pract 104:234-40. 2014
    ..To examine whether glomerular hemodynamic parameters in humans are associated with glycemic control indices, by simultaneously measuring clearance of inulin (Cin) and para-aminohippuric acid (CPHA)...
  59. ncbi request reprint Analyses of dendritic cell subsets in pregnancy
    T Yoshimura
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Am J Reprod Immunol 50:137-45. 2003
    ....
  60. ncbi request reprint Increased basal phosphorylation of mitogen-activated protein kinases and reduced responsiveness to inflammatory cytokines in neutrophils from patients with rheumatoid arthritis
    M Inaba
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    Clin Exp Rheumatol 26:52-60. 2008
    ....
  61. ncbi request reprint Impact of insulin resistance and nephropathy on homocysteine in type 2 diabetes
    M Emoto
    Second Department of Internal Medicine, Institute of Geriatrics and Medical Science, Osaka City University Medical School, Japan
    Diabetes Care 24:533-8. 2001
    ..To assess the impacts of insulin resistance and renal function on plasma total homocysteine (tHcy) levels in patients with type 2 diabetes with a wide range of nephropathy...
  62. ncbi request reprint Diabetes mellitus increases the severity of anemia in non-dialyzed patients with renal failure
    E Ishimura
    Second Department of Internal Medicine, Osaka City University Medical School, Japan
    J Nephrol 11:83-6. 1998
    ..494, p < 0.001). DM appeared to be a risk factor for the severity of anemia in patients with renal failure who were not receiving dialysis...
  63. ncbi request reprint Follow-up study of bedwetting from 3 to 5 years of age
    A Kawauchi
    Department of Urology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kyoto, Japan
    Urology 58:772-6. 2001
    ..CONCLUSIONS: Daytime incontinence and sex were the significant factors for bedwetting in infancy. Head circumference for boys and developmental delays in speaking and walking might also be important factors...
  64. ncbi request reprint Immunohistochemical studies on the distribution of nerve fibers in the human prostate with special reference to the anterior fibromuscular stroma
    T Iwata
    Department of Urology, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kyoto, Japan
    Prostate 48:242-7. 2001
    ..We recently reported the possible contribution of the AFMS to micturition. The aim of this study is to reveal the differences in the distribution of innervation between the AFMS and the other regions of the prostate...
  65. pmc Activation of granulocytes by direct interaction with dendritic cells
    M Tsuda
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Clin Exp Immunol 150:322-31. 2007
    ..Furthermore, we examined the involvement of adhesion molecules in the granulocyte-DC interaction, and found that CD209 participates to some extent in this interaction...
  66. ncbi request reprint Stimulatory effects of hepatocyte growth factor on hemopoiesis of SCF/c-kit system-deficient mice
    C Z Yu
    First Department of Pathology, Kansai Medical University, Osaka, Japan
    Stem Cells 16:66-77. 1998
    ..RBC, WBC, and platelet counts also increased. These results suggest that the SCF/c-kit system is not essential to hemopoiesis but that a compensatory system such as the HGF/c-met system functions in the SCF/c-kit system-deficient mice...
  67. ncbi request reprint Induction of immune-mediated hearing loss in SCID mice by injection of MRL/lpr mouse spleen cells
    H Iwai
    Department of Otorhinolaryngology, Kansai Medical University, Moriguchi, Osaka, Japan
    Hear Res 117:173-7. 1998
    ..These findings suggest that cell-mediated immunity is involved in the development of SHL and cochlear pathology...
  68. ncbi request reprint Thrombopoietin inhibits in vitro osteoclastogenesis from murine bone marrow cells
    T Wakikawa
    Department of Biochemistry, Osaka City University Medical School, Osaka, Japan
    Endocrinology 138:4160-6. 1997
    ..These data suggest that TPO inhibits osteoclastogenesis through stimulating thrombopoiesis and that TGFbeta and PDGF mediate the effect of TPO by impacting on macrophage-lineage cells as osteoclast precursors...
  69. ncbi request reprint Increased levels of C-reactive protein in hypothyroid patients and its correlation with arterial stiffness in the common carotid artery
    Toshiki Nagasaki
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Biomed Pharmacother 61:167-72. 2007
    ....
  70. ncbi request reprint Minimodeling reduces the rate of cortical bone loss in patients with secondary hyperparathyroidism
    Aiji Yajima
    Department of Nephrology, Towa Hospital, Tokyo, Japan
    Am J Kidney Dis 49:440-51. 2007
    ..Because bone formation by minimodeling has not yet been reported in cortical bone, we investigated the effects of cortical minimodeling on the decrease in rate of bone loss...
  71. ncbi request reprint Presence of abdominal aortic calcification is significantly associated with all-cause and cardiovascular mortality in maintenance hemodialysis patients
    Senji Okuno
    Kidney Center, Shirasagi Hospital, Osaka, Japan
    Am J Kidney Dis 49:417-25. 2007
    ....
  72. ncbi request reprint Preferential stiffening of central over peripheral arteries in type 2 diabetes
    Eiji Kimoto
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Diabetes 52:448-52. 2003
    ..In contrast, sex was associated with PWV of the peripheral arteries. Thus, type 2 diabetes had greater impact on PWV of the central arteries, and different factors were involved in PWV among different arterial regions...
  73. ncbi request reprint [Diabetic osteoporosis]
    Yasuro Kumeda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
    Nihon Rinsho 60:459-67. 2002
  74. ncbi request reprint Factors affecting progression of renal failure in patients with type 2 diabetes
    Hideki Ueda
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Diabetes Care 26:1530-4. 2003
    ..Hyperglycemia and hypertension are known to be risk factors for the development of proteinuria in patients with diabetes. Little is known, however, about predictors of progression of renal failure in diabetic patients...
  75. ncbi request reprint Influence of nutritional status on serum large N-truncated PTH, but not PTH(1-84) in hemodialysis patients
    Kaori Shidara
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Biomed Pharmacother 61:142-7. 2007
    ..We investigated whether PTH(7-84) and larger N-truncated PTH or PTH(1-84) might be affected by nutritional status in HD patients...
  76. ncbi request reprint Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients
    Koka Motoyama
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Metabolism 52:895-9. 2003
    ..In conclusion, the M416V polymorphism of GYS1 gene is not associated with insulin resistance in type 2 diabetes...
  77. ncbi request reprint [Diabetes mellitus and osteoporosis]
    Yasuro Kumeda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
    Nihon Rinsho 60:393-403. 2002
  78. ncbi request reprint Regulatory mechanisms of circulating fibroblast growth factor 23 in parathyroid diseases
    Yasuo Imanishi
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, Japan
    Ther Apher Dial 11:S32-7. 2007
    ....
  79. ncbi request reprint [Influence on atherosclerosis of improvement of bone mineral density after medication for osteoporosis]
    Shinsuke Yamada
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
    Nihon Rinsho 65:348-51. 2007
  80. ncbi request reprint [Primary osteoporosis--its diagnosis and treatment]
    Masaaki Inaba
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine
    Nihon Rinsho 65:485-9. 2007
  81. ncbi request reprint Clinical usefulness of the serum N-terminal propeptide of type I collagen as a marker of bone formation in hemodialysis patients
    Misako Ueda
    Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 40:802-9. 2002
    ..The present study was performed to investigate the clinical usefulness of serum PINP as a bone-formation marker in hemodialysis (HD) patients...
  82. ncbi request reprint Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis
    Yasuro Kumeda
    Division of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Arthritis Rheum 46:1489-97. 2002
    ....
  83. ncbi request reprint C-reactive protein is a significant predictor of vascular calcification of both aorta and hand arteries
    Eiji Ishimura
    Osaka City University Graduate School of Medicine, Osaka, Japan
    Semin Nephrol 24:408-12. 2004
    ....
  84. doi request reprint Reference intervals of serum tartrate-resistant acid phosphatase type 5b activity measured with a novel assay in Japanese subjects
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Abeno Ku, Osaka, 545 8585, Japan
    J Bone Miner Metab 26:265-70. 2008
    ..The reference intervals (logarithmic mean +/-1.96 SD) for men, premenopausal women, and postmenopausal women were 1.7-5.9 U/l, 1.2-4.4 U/l, and 2.5-7.6 U/l, respectively...
  85. ncbi request reprint Serum levels of TRAP5b, a new bone resorption marker unaffected by renal dysfunction, as a useful marker of cortical bone loss in hemodialysis patients
    Kaori Shidara
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka, 545 8585, Japan
    Calcif Tissue Int 82:278-87. 2008
    ..9%, respectively, for serum TRAP5b. Measurement of serum TRAP5b, as well as intact OC, may be a clinically relevant assay for estimation of bone metabolic status in HD patients, although serum intact OC accumulates in uremic serum...
  86. ncbi request reprint Central pulse wave velocity is responsible for increased brachial-ankle pulse wave velocity in subclinical hypothyroidism
    Toshiki Nagasaki
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Osaka, Japan
    Clin Endocrinol (Oxf) 66:304-8. 2007
    ..The current study was performed to assess which arterial segment is responsible for enhanced baPWV in subclinical hypothyroidism...
  87. ncbi request reprint Association of serum fetuin-A with carotid arterial stiffness
    Katsuhito Mori
    Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    Clin Endocrinol (Oxf) 66:246-50. 2007
    ..The objective of this study was to investigate the association between serum fetuin-A levels and arterial stiffness, a functional property of atherosclerosis, in healthy subjects...
  88. ncbi request reprint Serum concentrations of cross-linked N-telopeptides of type I collagen: new marker for bone resorption in hemodialysis patients
    Yoshifumi Maeno
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Japan
    Clin Chem 51:2312-7. 2005
    ..Urinary cross-linked N-telopeptide of type I collagen (NTX) is a reliable bone resorption marker in patients with metabolic bone disease. We assessed a clinically available serum NTX assay suitable for anuric patients on hemodialysis (HD)...
  89. ncbi request reprint Aortic calcification in haemodialysis patients with diabetes mellitus
    Hiromichi Taniwaki
    Inoue Hospital, Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Nephrol Dial Transplant 20:2472-8. 2005
    ..This study examined the risk factors of aortic calcification in a large number of haemodialysis patients, and compared risk factors between diabetic and non-diabetic patients...
  90. ncbi request reprint Serum BAP as the clinically useful marker for predicting BMD reduction in diabetic hemodialysis patients with low PTH
    Misako Ueda
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City, University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Life Sci 77:1130-9. 2005
    ..In conclusion, serum BAP is a clinically useful bone formation marker to predict the BMD reduction in DM HD patients with low level of PTH...
  91. ncbi request reprint C-reactive protein is a significant predictor of decrease in fat mass in hemodialysis patients
    Yoko Fujino
    Shirasagi Hospital Kidney Center, Osaka City University Graduate School of Medicine, Osaka, Japan
    Biomed Pharmacother 59:264-8. 2005
    ..Chronic inflammation, represented by higher CRP levels, is a significant factor affecting decrease in fat mass, and is related to poorer nutritional status...
  92. ncbi request reprint Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients
    Eiji Ishimura
    Department of Nephrology, Osaka City University Graduate School of Medicine, Osaka, Japan
    Am J Kidney Dis 45:859-65. 2005
    ..Although an increased serum phosphate concentration is a significant risk factor for vascular calcification, it is unclear whether serum phosphate level is a risk factor for increased arterial wall thickness in hemodialysis patients...
  93. ncbi request reprint Arterial wall stiffness is associated with peripheral circulation in patients with type 2 diabetes
    Akane Kizu
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Atherosclerosis 170:87-91. 2003
    ..Thus, arterial wall stiffness of femoral artery appears to be a major determinant of peripheral circulation in patients with type 2 diabetes...
  94. ncbi request reprint Roles of metabolic and endocrinological alterations in atherosclerosis and cardiovascular disease in renal failure: another form of metabolic syndrome
    Yoshiki Nishizawa
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Medical School, Osaka, Japan
    Semin Nephrol 24:423-5. 2004
    ..It is expected that treatment of these metabolic and endocrinologic alterations would improve the survival of patients with renal failure...
  95. ncbi request reprint Arterial wall thickness is associated with insulin resistance in type 2 diabetic patients
    Shigehiko Fujiwara
    Metabolism, Endocrinology and Molecular Medicine, Department of Internal Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Atheroscler Thromb 10:246-52. 2003
    ..0001, respectively). In conclusion, insulin resistance is associated with both CA-IMT and FA-IMT in type 2 diabetic patients, suggesting that it is an independent risk factor for the development of atherosclerosis in type 2 diabetes...
  96. ncbi request reprint Effect and safety of intermittent weekly administration of human parathyroid hormone 1-34 in patients with primary osteoporosis evaluated by histomorphometry and microstructural analysis of iliac trabecular bone before and after 1 year of treatment
    Takami Miki
    Department of Geriatric Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka, Japan
    J Bone Miner Metab 22:569-76. 2004
    ..Intermittent weekly subcutaneous injections of hPTH (1-34) for 48 weeks increased trabecular bone volume and improved microstructure, without causing the appearance of abnormal bone elements in primary osteoporosis...
  97. ncbi request reprint Inflammation and bone resorption as independent factors of accelerated arterial wall thickening in patients with rheumatoid arthritis
    Mayumi Nagata-Sakurai
    Osaka City University Graduate School of Medicine, Osaka, Japan
    Arthritis Rheum 48:3061-7. 2003
    ..The present longitudinal study was performed to determine whether the change in arterial thickness was accelerated in RA patients and to determine which factor was important in the progression of arterial wall changes...
  98. ncbi request reprint Serum levels of C-terminal telopeptide of type I collagen: a useful new marker of cortical bone loss in hemodialysis patients
    Senji Okuno
    Shirasagi Hospital, 7 11 23 Kumata, Higashisumiyoshi ku, 546 0002 Osaka, Japan
    Osteoporos Int 16:501-9. 2005
    ..In conclusion, serum measurement of beta-CTx may provide a new commercially viable and relevant serum assay to reflect cortical bone resorption in hemodialysis patients...
  99. ncbi request reprint Short-term aerobic exercise improves arterial stiffness in type 2 diabetes
    Hisayo Yokoyama
    Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Diabetes Res Clin Pract 65:85-93. 2004
    ..To investigate whether: (1) aerobic exercise decreases arterial stiffness and (2) reduction in arterial stiffness is associated with improvement in insulin resistance in type 2 diabetes...
  100. ncbi request reprint Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population
    Tetsuo Shoji
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
    Nephrol Dial Transplant 19:179-84. 2004
    ..We hypothesized that treatment with vitamin D(3) may be beneficial for survival in patients with end-stage renal disease (ESRD)...
  101. ncbi request reprint Significance of intima-media thickness in femoral artery in the determination of calcaneus osteo-sono index but not of lumbar spine bone mass in healthy Japanese people
    Shinsuke Yamada
    Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, 545 8585, Osaka, Japan
    Osteoporos Int 16:64-70. 2005
    ....