T Hirose

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. ncbi request reprint Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain
    T Hirose
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Japan
    Eur J Biochem 267:2113-21. 2000
  2. ncbi request reprint PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons
    T Hirose
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Suita, Japan
    Eur J Biochem 249:481-8. 1997
  3. ncbi request reprint RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis
    T Hirose
    Cell Biology Section, Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709
    Gene 152:247-51. 1995
  4. pmc Genomic organization of the S locus: Identification and characterization of genes in SLG/SRK region of S(9) haplotype of Brassica campestris (syn. rapa)
    G Suzuki
    Graduate School of Agricultural Science, Tohoku University, Sendai 981 8555, Japan
    Genetics 153:391-400. 1999
  5. ncbi request reprint Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
    Y Sugiyama
    Department of Molecular Biology, Yokohama City University School of Medicine, Kanazawa Ku, Yokohama 236 0004, Japan
    J Biol Chem 275:1095-104. 2000
  6. ncbi request reprint cDNA cloning and tissue specific expression of a gene for sucrose transporter from rice (Oryza sativa L.)
    T Hirose
    Department of Plant Physiology, National Institute of Agrobiological Resources, Ibaraki, Japan
    Plant Cell Physiol 38:1389-96. 1997
  7. pmc An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    Y Izumi
    Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
    J Cell Biol 143:95-106. 1998
  8. ncbi request reprint Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiation
    W Lei
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 18:167-76. 1997
  9. ncbi request reprint ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle
    T Hirose
    Cell Biology Section, Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709
    Biochem Biophys Res Commun 205:1976-83. 1994
  10. ncbi request reprint LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    Y Gong
    Cell 107:513-23. 2001

Detail Information

Publications49

  1. ncbi request reprint Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain
    T Hirose
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Japan
    Eur J Biochem 267:2113-21. 2000
    ..These findings suggest that Trap is a physiological partner of PCTAIRE 2 in terminally differentiated neurons...
  2. ncbi request reprint PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons
    T Hirose
    Division of Protein Metabolism, Institute for Protein Research, Osaka University, Suita, Japan
    Eur J Biochem 249:481-8. 1997
    ..These findings suggest that PCTAIRE 2 is a Ser/Thr kinase that might play a unique role in terminally differentiated neurons...
  3. ncbi request reprint RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis
    T Hirose
    Cell Biology Section, Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709
    Gene 152:247-51. 1995
    ..Our observations suggest that this putative transcription factor plays a role in the regulation of gene expression particularly during the post-meiotic phase of spermatogenesis...
  4. pmc Genomic organization of the S locus: Identification and characterization of genes in SLG/SRK region of S(9) haplotype of Brassica campestris (syn. rapa)
    G Suzuki
    Graduate School of Agricultural Science, Tohoku University, Sendai 981 8555, Japan
    Genetics 153:391-400. 1999
    ..The small cysteine-rich protein was similar to a pollen coat protein, named PCP-A1, which had previously been shown to bind SLG...
  5. ncbi request reprint Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
    Y Sugiyama
    Department of Molecular Biology, Yokohama City University School of Medicine, Kanazawa Ku, Yokohama 236 0004, Japan
    J Biol Chem 275:1095-104. 2000
    ..Taken together, the results suggest that muscle cells develop two kinds of stress response systems composed of diverged sHSP members, and that these systems work independently in muscle maintenance and differentiation...
  6. ncbi request reprint cDNA cloning and tissue specific expression of a gene for sucrose transporter from rice (Oryza sativa L.)
    T Hirose
    Department of Plant Physiology, National Institute of Agrobiological Resources, Ibaraki, Japan
    Plant Cell Physiol 38:1389-96. 1997
    ..Transcript was observed at high levels in panicles after heading, particularly in the portion containing endosperm and embryo. In addition, expression of OsSUT1 was high in etiolated seedlings and decreased during light-induced greening...
  7. pmc An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    Y Izumi
    Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
    J Cell Biol 143:95-106. 1998
    ....
  8. ncbi request reprint Cloning of the human orphan receptor germ cell nuclear factor/retinoid receptor-related testis-associated receptor and its differential regulation during embryonal carcinoma cell differentiation
    W Lei
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 18:167-76. 1997
    ..Our observations suggest that GCNF/RTR plays a role in the control of gene expression in early embryogenesis and during spermatogenesis...
  9. ncbi request reprint ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle
    T Hirose
    Cell Biology Section, Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709
    Biochem Biophys Res Commun 205:1976-83. 1994
    ..ROR gamma was localized on human chromosome 1. Northern blot analysis using RNA from multiple tissues indicated that ROR gamma is expressed in several tissues but is most highly expressed in skeletal muscle...
  10. ncbi request reprint LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    Y Gong
    Cell 107:513-23. 2001
    ..These data indicate that Wnt-mediated signaling via LRP5 affects bone accrual during growth and is important for the establishment of peak bone mass...
  11. ncbi request reprint ELMO1 increases expression of extracellular matrix proteins and inhibits cell adhesion to ECMs
    A Shimazaki
    Laboratory for Diabetic Nephropathy, SNP Research Center, The Institute of Physical and Chemical Research, Yokohama, Kanagawa, Japan
    Kidney Int 70:1769-76. 2006
    ..These results suggest that the ELMO1 contributes to the development and progression of chronic glomerular injury through the dysregulation of ECM metabolism and the reduction in cell adhesive properties to ECMs...
  12. ncbi request reprint Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element
    A Medvedev
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Gene 181:199-206. 1996
    ..ROR alpha 1 and ROR gamma inhibit the transactivation induced by GAL4(DBD)-ROR gamma in fibroblast D1 cells suggesting that these receptors compete for binding to the same coactivators...
  13. ncbi request reprint Genomic structure and chromosomal mapping of the nuclear orphan receptor ROR gamma (RORC) gene
    A Medvedev
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Genomics 46:93-102. 1997
    ..1-2.2. The human ROR gamma was mapped to chromosome region 1q21. The results demonstrate that the ROR gamma genes are located in chromosomal regions that are syntenic between mouse and human...
  14. ncbi request reprint Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells
    S Austin
    Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA
    Cell Growth Differ 9:267-76. 1998
    ....
  15. ncbi request reprint Expression of germ cell nuclear factor (GCNF/RTR) during spermatogenesis
    Y L Zhang
    State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry, Chinese Academy of Sciences, China
    Mol Reprod Dev 50:93-102. 1998
    ..These studies suggest that GCNF/RTR may regulate transcription during spermatogenesis, particularly in round spermatids just prior to the initiation of nuclear elongation and condensation...
  16. pmc Cloning and sequence analysis of cDNA for rat angiotensinogen
    H Ohkubo
    Proc Natl Acad Sci U S A 80:2196-200. 1983
    ....
  17. ncbi request reprint Molecular cloning and expression analysis of a gene for a sucrose transporter in maize (Zea mays L.)
    N Aoki
    Japan International Research Center for Agricultural Sciences, Ibaraki, Japan
    Plant Cell Physiol 40:1072-8. 1999
    ....
  18. ncbi request reprint Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice
    Y Tamura
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 113 8421, Japan
    Diabetologia 50:131-41. 2007
    ..To investigate the mechanism involved, we examined the role of nuclear factor kappaB (NF-kappaB), the distal target of IKK, in hepatic glucose metabolism...
  19. ncbi request reprint Dynamic changes in protein components of the tight junction during liver regeneration
    Y Takaki
    Department of Molecular Biology, Yokohama City University School of Medicine, Kanazawa-ku, Yokohama 236-0004, Japan
    Cell Tissue Res 305:399-409. 2001
    ....
  20. ncbi request reprint PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
    T Yamanaka
    Department of Molecular Biology, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan
    Genes Cells 6:721-31. 2001
    ....
  21. ncbi request reprint TNF-alpha inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPbeta and delta
    S Kurebayashi
    Department of Molecular Medicine, Osaka University Medical School, Suita, Japan
    Endocr J 48:249-53. 2001
    ..Our results suggest that TNF-alpha inhibits adipocyte differentiation independently of the downregulation of C/EBPbeta and C/EBPdelta...
  22. pmc The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
    K Ebnet
    Institute of Cell Biology, ZMBE, University of Muenster, D 48149 Muenster, Germany
    EMBO J 20:3738-48. 2001
    ..Our data suggest that the ASIP/PAR-3-aPKC complex is tethered to tight junctions via its association with JAM, indicating a potential role for JAM in the generation of cell polarity in epithelial cells...
  23. ncbi request reprint Interaction of phytoestrogens with estrogen receptors alpha and beta
    K Morito
    Department of Molecular and Cellular Biology, Faculty of Pharmaceutical Sciences, Kanazawa University, Ishikawa, Japan
    Biol Pharm Bull 24:351-6. 2001
    ..Although genistin binds more weakly to the receptors and induces transcription less than does genistein, it stimulates the growth of MCF-7 cells more strongly than does genistein...
  24. pmc Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
    A Suzuki
    Department of Molecular Biology, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
    J Cell Biol 152:1183-96. 2001
    ..These results indicate that aPKC is involved in the evolutionarily conserved PAR protein complex, and plays critical roles in the development of the junctional structures and apico-basal polarization of mammalian epithelial cells...
  25. ncbi request reprint RNA editing sites in tobacco chloroplast transcripts: editing as a possible regulator of chloroplast RNA polymerase activity
    T Hirose
    Center for Gene Research, Nagoya University, Japan
    Mol Gen Genet 262:462-7. 1999
    ..coli RNA polymerase. Editing of this site is partial and the extent of editing depends on developmental conditions, suggesting that editing is, at least in part, involved in the regulation of chloroplast-encoded RNA polymerase activity...
  26. doi request reprint Pleomorphic xanthoastrocytoma: a comparative pathological study between conventional and anaplastic types
    T Hirose
    Department of Pathology, Saitama Medical School, Saitama, Japan
    Histopathology 52:183-93. 2008
    ..To facilitate the understanding and correct diagnosis of the anaplastic variant of pleomorphic xanthoastrocytoma (PXA)...
  27. ncbi request reprint Structural organisation and chromosomal mapping of the human Id-3 gene
    R W Deed
    CRC Department of Gene Regulation, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK
    Gene 151:309-14. 1994
    ..1 by fluorescence in situ hybridisation (FISH) and, using the same FISH technique, we have detected heterogeneity in tumour-associated 1p36 chromosome translocations...
  28. ncbi request reprint Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence
    T Kubo
    Eur J Biochem 149:5-13. 1985
    ..The relative pattern of regional homology is similar for all four subunit precursors...
  29. ncbi request reprint Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers
    H Yoshioka
    J Biol Chem 262:1706-11. 1987
    ..RNA blot analysis using a synthetic oligonucleotide specific for P-450(M-1) revealed that P-450(M-1) mRNA was expressed exclusively in the livers of mature male rats in a sex-specific manner, but not in other tissues so far examined...
  30. pmc Isolation and characterization of bovine and mouse terminal deoxynucleotidyltransferase cDNAs expressible in mammalian cells
    O Koiwai
    Nucleic Acids Res 14:5777-92. 1986
    ..Bovine TdT expressed in COS7 cells by nearly full-length cDNA clone was localized in the nucleus and the translational product of pOK103 lacking the nuclear-localization-sequence was localized in the cytoplasm...
  31. ncbi request reprint The complete nucleotide sequence of the group II RNA coliphage GA
    Y Inokuchi
    J Biochem 99:1169-80. 1986
    ....
  32. ncbi request reprint DQw1 beta gene from HLA-DR2-Dw12 consists of six exons and expresses multiple DQw1 beta polypeptides through alternative splicing
    K Tsukamoto
    Immunogenetics 25:343-6. 1987
  33. ncbi request reprint Primary structure of the receptor for calcium channel blockers from skeletal muscle
    T Tanabe
    Nature 328:313-8. 1987
    ....
  34. ncbi request reprint Primary structure of human poly(ADP-ribose) synthetase as deduced from cDNA sequence
    T Kurosaki
    Department of Medical Chemistry, Kochi Medical School, Japan
    J Biol Chem 262:15990-7. 1987
    ..These facts suggest the possibility that the physiological function of poly(ADP-ribose) synthetase lies in its ability to bind to DNA and to control transformation of living eukaryotic cells like the cases of those oncogene products...
  35. ncbi request reprint Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
    H Takeshima
    Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Japan
    Nature 339:439-45. 1989
    ....
  36. ncbi request reprint Molecular genetic analysis of myelin-deficient mice: shiverer mutant mice show deletion in gene(s) coding for myelin basic protein
    M Kimura
    J Neurochem 44:692-6. 1985
    ....
  37. ncbi request reprint Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor
    H Kakidani
    Nature 298:245-9. 1982
    ..This precursor protein, like adrenal preproenkephalin and the corticotropin/beta-lipotropin precursor, comprises multiple repetitive units and a cysteine-containing amino-terminal sequence preceded by a signal peptide...
  38. pmc Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin
    S V Suggs
    Proc Natl Acad Sci U S A 78:6613-7. 1981
    ..The clone has been characterized by blotting and nucleotide sequence analysis. The cloned beta 2-microglobulin sequence contains 217 base pairs of the 3' untranslated region of the mRNA and 328 base pairs (97%) of the coding region...
  39. ncbi request reprint Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor
    H Nawa
    Nature 306:32-6. 1983
    ..This new tachykinin sequence is bounded by paired basic amino acids Lys-Arg, which suggests that, like substance P, it can be liberated from the precursor and may serve as an endogenous hormone or neuromediator in mammalian organisms...
  40. ncbi request reprint TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily
    T Hirose
    Cell Biology Section, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
    Mol Endocrinol 8:1667-80. 1994
    ..In the testis, TAK1 appears to control gene expression during spermatogenesis, particularly during the meiotic phase...
  41. ncbi request reprint Cloning of the gene encoding the murine orphan receptor TAK1 and cell-type-specific expression in testis
    T Hirose
    Cell Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Gene 163:239-42. 1995
    ..Southern analysis using genomic DNA prepared from a panel of hamster/human and mouse/human hybrid cell lines indicated that the TAK1 gene is located on human chromosome 3...
  42. ncbi request reprint Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor
    M Noda
    Nature 305:818-23. 1983
    ..The protein-coding sequence of the human AChR alpha-subunit precursor gene is divided by eight introns into nine exons, which seem to correspond to different structural and functional domains of the subunit precursor molecule...
  43. pmc Molecular cloning and nucleotide sequence of cDNA for mRNA of mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex
    K Morohashi
    Proc Natl Acad Sci U S A 81:4647-51. 1984
    ..Only two cysteinyl residues are present in the mature form of P-450(SCC), one of which is located in the middle of the conserved sequence, confirming the function of this cysteinyl residue as the fifth ligand of the heme...
  44. pmc Primary structures of bovine liver low molecular weight kininogen precursors and their two mRNAs
    H Nawa
    Proc Natl Acad Sci U S A 80:90-4. 1983
    ..This suggests that the mRNAs are transcribed from the same gene to generate two LMW kininogen precursors differing only in the internally homologous sequences...
  45. ncbi request reprint Primary structure of beta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence
    T Tanabe
    Eur J Biochem 144:11-7. 1984
    ....
  46. ncbi request reprint mRNA sequence for human cardiodilatin-atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria
    K Nakayama
    Nature 310:699-701. 1984
    ....
  47. ncbi request reprint Isolation and structural organization of the human preproenkephalin B gene
    S Horikawa
    Nature 306:611-4. 1983
    ....
  48. ncbi request reprint Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin
    M Noda
    Nature 295:202-6. 1982
    ..The enkephalin and extended enkephalin sequences are each bounded by paired basic amino acid residues. Preproenkephalin may represent a multi-hormone precursor, like the corticotropin-beta-lipotropin precursor...
  49. ncbi request reprint Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
    U B Kaupp
    Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan
    Nature 342:762-6. 1989
    ..Expression of the complementary DNA produces cyclic GMP-gated channel activity in Xenopus oocytes...