Research Topics
| Katsuhiko HataSummaryAffiliation: Osaka University Country: Japan Publications
| Collaborators
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Detail Information
Publications
Unc5B associates with LARG to mediate the action of repulsive guidance moleculeKatsuhiko Hata
Department of Molecular Neuroscience, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
J Cell Biol 184:737-50. 2009..Focal adhesion kinase (FAK) is involved in RGMa-induced tyrosine phosphorylation of LARG as well as RhoA activation. These findings uncover the molecular basis for diverse functions mediated by RGMa...
Neogenin, a receptor for bone morphogenetic proteinsMeiko Hagihara
Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
J Biol Chem 286:5157-65. 2011..Taken together, our findings suggest that neogenin negatively regulates the functions of BMP and that this effect of neogenin is mediated by the activation of RhoA...
Improvement in protocol to generate homogeneous glutamatergic neurons from mouse embryonic stem cells reduced apoptosisRyosuke Fujiki
Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
Biochem Biophys Res Commun 430:604-9. 2013..As a result, neither of them had pro-survival effect on pure glutamatergic neuronal population...
Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin βRyo Ohara
Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2 2, Yamadaoka, Suita, Osaka 565 0871, Japan
Biochem Biophys Res Commun 405:697-702. 2011..Taken together, these results suggest that retrograde transport of injury-induced signals in injured axons play key roles in the axotomy-induced axonogenesis of hippocampal neurons...
Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance moleculeTakekazu Kubo
Department of Neurobiology, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, Japan, and BioClues Inc, Nihonbashi, Chuo Ku, Tokyo, Japan
J Neurochem 105:113-26. 2008..We conclude that Rho-kinase-dependent activation of MIIA via MLC phosphorylation induces F-actin reduction and growth cone collapse and the subsequent neurite retraction/outgrowth inhibition triggered by RGMa...
Limited functional recovery in rats with complete spinal cord injury after transplantation of whole-layer olfactory mucosa: laboratory investigationMasanori Aoki
Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan
J Neurosurg Spine 12:122-30. 2010..To investigate the potential of the OM to restore motor function, the authors developed a rat model of SCI and delayed transplantation of syngenic OM...
