Kunio Awazu

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. ncbi Effects of near-infra-red laser irradiation on adenosine triphosphate and adenosine diphosphate contents of rat brain tissue
    Noriko Mochizuki-Oda
    Institute of Free Electron Laser, Graduate School of Engineering, Osaka University, Hirakata, Osaka 573 0128, Japan
    Neurosci Lett 323:207-10. 2002
  2. ncbi Wavelength and average power density dependency of the surface modification of root dentin using an MIR-FEL
    Manabu Heya
    Institute of Free Electron Laser, Graduate School of Engineering, Osaka University, 2 9 5 Tsuda Yamate, Hirakata, Osaka 573 0128, Japan
    Lasers Surg Med 32:349-58. 2003
  3. doi In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
    Makoto Sakai
    Osaka University, Graduate School of Engineering, Osaka 565 0871, Japan
    J Biomed Opt 17:77009. 2012
  4. ncbi In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
    Makoto Sakai
    Osaka University, Graduate School of Engineering, Osaka 565 0871, Japan
    J Biomed Opt 17:077009. 2012
  5. doi A novel photodynamic therapy for drug-resistant prostate cancer cells using porphyrus envelope as a novel photosensitizer
    Masaya Yamauchi
    Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan Electronic address
    Photodiagnosis Photodyn Ther 11:48-54. 2014
  6. doi Development of a stigmatic mass microscope using laser desorption∕ionization and a multi-turn time-of-flight mass spectrometer
    Hisanao Hazama
    Osaka University, Graduate School of Engineering, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Biomed Opt 16:046007. 2011
  7. ncbi Unimolecular and collision-induced dissociation of singly-charged mono-bromide silver clusters Ag(x)Br(+) (x = 2, 4, 6, 8, 10)
    Hirofumi Nagao
    Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    Eur J Mass Spectrom (Chichester, Eng) 15:459-69. 2009
  8. ncbi Evaluation of oxygen consumption of culture medium and in vitro photodynamic effect of talaporfin sodium in lung tumor cells
    Yutaka Tomioka
    Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka, Japan
    Photomed Laser Surg 28:385-90. 2010
  9. doi Novel laser therapy and diagnosis using mid-infrared laser
    Kunio Awazu
    Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka 565 0871, Japan
    Conf Proc IEEE Eng Med Biol Soc 2009:4150-3. 2009
  10. doi Chondrogenic mRNA expression in prechondrogenic cells after blue laser irradiation
    Toshihiro Kushibiki
    Frontier Research Center, Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Photochem Photobiol B 98:211-5. 2010

Collaborators

  • Toshihiro Kushibiki
  • Yasufumi Kaneda
  • Hiroyuki Nakamura
  • Michisato Toyoda
  • Shigeo Hayakawa
  • Yilong Cui
  • Toshiyuki Fujinaka
  • Ko ichi Iwatsuki
  • Junji Kato
  • Hisanao Hazama
  • Katsunori Ishii
  • Makoto Sakai
  • Hirofumi Nagao
  • Norihiro Honda
  • Naohiro Fujimoto
  • Katsuyoshi Masuda
  • Hiroki Kannen
  • Ryuji Hiraguchi
  • Masaya Yamauchi
  • Yutaka Tomioka
  • Yasuhide Naito
  • Manabu Heya
  • Taizo Kanai
  • Yoshikazu Nakajima
  • Kenichirou Senoo
  • Tatsuya Fujino
  • Noriko Mochizuki-Oda
  • Yukinori Yahata
  • Shoji Tachikawa
  • Hidetoshi Yoshimura
  • Takuya Nanjo
  • Toshio Tashima
  • Takaya Terada
  • Jun Aoki
  • Kenichi Fujii
  • Masayuki Saiki
  • Shuichi Shimma
  • Kenichi Iwamoto
  • Kazuya Kawamura
  • Toshio Ichihara
  • Sachiko Yoshihashi-Suzuki
  • Ren Suzuki
  • Toshiki Yoshimine
  • Sachiko Suzuki
  • Shu Sano
  • Yuko Fukami
  • Nobuhiko Takagi
  • Yosky Kataoka
  • Hisao Yamada

Detail Information

Publications26

  1. ncbi Effects of near-infra-red laser irradiation on adenosine triphosphate and adenosine diphosphate contents of rat brain tissue
    Noriko Mochizuki-Oda
    Institute of Free Electron Laser, Graduate School of Engineering, Osaka University, Hirakata, Osaka 573 0128, Japan
    Neurosci Lett 323:207-10. 2002
    ..4-4.7 degrees C during the irradiation of both wavelengths. These results suggest that the increase in tissue ATP content did not result from the thermal effect, but from a specific effect of the laser operated at the 830-nm wavelength...
  2. ncbi Wavelength and average power density dependency of the surface modification of root dentin using an MIR-FEL
    Manabu Heya
    Institute of Free Electron Laser, Graduate School of Engineering, Osaka University, 2 9 5 Tsuda Yamate, Hirakata, Osaka 573 0128, Japan
    Lasers Surg Med 32:349-58. 2003
    ..The key aspect is to bring about effective surface modification of the root dentin while minimizing the unwanted removal of the underlying dentin...
  3. doi In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
    Makoto Sakai
    Osaka University, Graduate School of Engineering, Osaka 565 0871, Japan
    J Biomed Opt 17:77009. 2012
    ..The cytotoxicity of conventional 5-ALA was enhanced by the addition of HVJ-E vector. In conclusion, HVJ-E vector improved the uptake of photosensitizers and the PDT effect...
  4. ncbi In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
    Makoto Sakai
    Osaka University, Graduate School of Engineering, Osaka 565 0871, Japan
    J Biomed Opt 17:077009. 2012
    ..The cytotoxicity of conventional 5-ALA was enhanced by the addition of HVJ-E vector. In conclusion, HVJ-E vector improved the uptake of photosensitizers and the PDT effect...
  5. doi A novel photodynamic therapy for drug-resistant prostate cancer cells using porphyrus envelope as a novel photosensitizer
    Masaya Yamauchi
    Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan Electronic address
    Photodiagnosis Photodyn Ther 11:48-54. 2014
    ..On the basis of several of its key characteristics, PDT is considered to be a promising novel method for treating drug-resistant prostate cancer...
  6. doi Development of a stigmatic mass microscope using laser desorption∕ionization and a multi-turn time-of-flight mass spectrometer
    Hisanao Hazama
    Osaka University, Graduate School of Engineering, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Biomed Opt 16:046007. 2011
    ....
  7. ncbi Unimolecular and collision-induced dissociation of singly-charged mono-bromide silver clusters Ag(x)Br(+) (x = 2, 4, 6, 8, 10)
    Hirofumi Nagao
    Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    Eur J Mass Spectrom (Chichester, Eng) 15:459-69. 2009
    ..The present results were consistently explained by SJM. The dissociation behavior of Ag(2)Br(+) can be explained on the basis of the calculated thermochemical data...
  8. ncbi Evaluation of oxygen consumption of culture medium and in vitro photodynamic effect of talaporfin sodium in lung tumor cells
    Yutaka Tomioka
    Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka, Japan
    Photomed Laser Surg 28:385-90. 2010
    ....
  9. doi Novel laser therapy and diagnosis using mid-infrared laser
    Kunio Awazu
    Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka 565 0871, Japan
    Conf Proc IEEE Eng Med Biol Soc 2009:4150-3. 2009
    ..This paper showed a novel therapeutic and diagnostic applications using tunable MIR laser...
  10. doi Chondrogenic mRNA expression in prechondrogenic cells after blue laser irradiation
    Toshihiro Kushibiki
    Frontier Research Center, Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Photochem Photobiol B 98:211-5. 2010
    ..As this technique could readily be applied in situ to control the differentiation of cells at an implanted site within the body, this approach may have therapeutic potential for the restoration of damaged or diseased tissue...
  11. ncbi Blue laser irradiation enhances extracellular calcification of primary mesenchymal stem cells
    Toshihiro Kushibiki
    Frontier Research Base for Global Young Researchers, Frontier Research Center, Graduate School of Engineering, Osaka University, Osaka, Japan
    Photomed Laser Surg 27:493-8. 2009
    ..Here we show that laser irradiation can direct the extracellular calcification of mouse MSCs by altering the intracellular localization of the circadian rhythm protein cryptochrome 1 (CRY1)...
  12. ncbi Free-electron-laser-induced shock-wave control and mechanistic analysis using pulse control
    Taizo Kanai
    Division of Sustainable Energy and Environmental Engineering, Osaka University, 2 6 Yamadaoka, Suita, Osaka 565 0871, Japan
    Appl Opt 47:5862-70. 2008
    ..With this system, we have controlled photoinduced shock waves and determine the mechanism of interaction during FEL-induced tissue ablation...
  13. pmc Controlling osteogenesis and adipogenesis of mesenchymal stromal cells by regulating a circadian clock protein with laser irradiation
    Toshihiro Kushibiki
    1 Frontier Research Center, Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka, 565 0871, Japan
    Int J Med Sci 5:319-26. 2008
    ..Furthermore, this model system may be useful for exploring the crosstalk between circadian rhythm and cell differentiation...
  14. ncbi Alternative denervation using laser irradiation in lumbar facet syndrome
    Koichi Iwatsuki
    Department of Neurosurgery, Osaka University Medical School, Suita, Osaka, Japan
    Lasers Surg Med 39:225-9. 2007
    ..The target of surgical techniques is the transverse process bases where the medial nerve branches innervated the facet. However, highly variable success rates have been demonstrated in different series...
  15. ncbi Percutaneous laser disc decompression for lumbar disc hernia: indications based on Lasegue's Sign
    Koichi Iwatsuki
    Department of Neurosurgery, Osaka University Medical School, Osaka, Japan
    Photomed Laser Surg 25:40-4. 2007
    ..The present study was conducted to establish reasonable indications of patient neurological manifestations for use of percutaneous laser disc decompression (PLDD)...
  16. doi Comparison of mass spectra of peptides in different matrices using matrix-assisted laser desorption/ionization and a multi-turn time-of-flight mass spectrometer, MULTUM-IMG
    Hisanao Hazama
    Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    Rapid Commun Mass Spectrom 22:1461-6. 2008
    ....
  17. doi Quantitative estimates of vascularity in a collagen-based cell scaffold containing basic fibroblast growth factor by noninvasive near-infrared spectroscopy for regenerative medicine
    Toshihiro Kushibiki
    Frontier Research Base for Global Young Researchers, Frontier Research Center, Graduate School of Engineering, Osaka, Japan
    Photomed Laser Surg 26:247-50. 2008
    ....
  18. doi Differential effects of photodynamic therapy on morphologically distinct tumor cells derived from a single precursor cell
    Toshihiro Kushibiki
    Frontier Research Base for Global Young Researchers, Frontier Research Center, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan
    Cancer Lett 268:244-51. 2008
    ..Understanding tumor cell heterogeneity for clinical applications of PDT will help in the design of new interventions and potentially improve long-term survival of PDT treated patients...
  19. ncbi Medical application of an infrared free-electron laser: selective removal of cholesterol ester in carotid artery atheromatous plaques
    Yoshikazu Nakajima
    Department of Neurosurgery, Graduate School of Medicine, Osaka University, Suita, Japan
    J Neurosurg 104:426-8. 2006
    ..The purpose of this study was to determine the effectiveness of infrared free-electron laser (FEL) irradiation of cholesterol esters in human carotid artery (CA) atheromas...
  20. ncbi Continuous Flow Atmospheric Pressure Laser Desorption/Ionization Using a 6-7-µm-Band Mid-Infrared Tunable Laser for Biomolecular Mass Spectrometry
    Ryuji Hiraguchi
    Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    Int J Mol Sci 15:10821-34. 2014
    ..This ionization technique has potential for the interface of liquid chromatography/mass spectrometry (LC/MS). ..
  21. ncbi Development of laser ionization techniques for evaluation of the effect of cancer drugs using imaging mass spectrometry
    Hiroki Kannen
    Graduate School of Engineering, Osaka University, 2 1 Yamadaoka, Suita, Osaka 565 0871, Japan
    Int J Mol Sci 15:11234-44. 2014
    ..Moreover, we detected docetaxel with the zeolite matrix using the droplet method, and detected PpIX by fluorescence and IMS with α-cyano-4-hydroxycinnamic acid (CHCA) using the spray method. ..
  22. doi In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
    Makoto Sakai
    Osaka University, Graduate School of Engineering, Osaka 565 0871, Japan
    J Biomed Opt 17:078002. 2012
    ..The cytotoxicity of conventional 5-ALA was enhanced by the addition of HVJ-E vector. In conclusion, HVJ-E vector improved the uptake of photosensitizers and the PDT effect...
  23. doi Determination of the tumor tissue optical properties during and after photodynamic therapy using inverse Monte Carlo method and double integrating sphere between 350 and 1000 nm
    Norihiro Honda
    Osaka University, Medical Beam Physics Laboratory, Graduate School of Engineering, 2 1 A14 Yamadaoka, Suita, Osaka 565 0871, Japan
    J Biomed Opt 16:058003. 2011
    ..0 times, which results in the optical penetration depth decreased by 1.4 to 1.8 times. To ensure an effective procedure, the adjustment of laser parameters for the decreasing penetration depth is recommended for the re-irradiation of PDT...
  24. doi Development of selective laser treatment techniques using mid-infrared tunable nanosecond pulsed laser
    Katsunori Ishii
    Medical Beam Phisics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, 565 0871, Japan
    Conf Proc IEEE Eng Med Biol Soc 2010:1614-7. 2010
    ..This paper showed a novel selective therapeutic technique for a laser angioplasty of atherosclerotic plaques and a laser dental surgery of a carious dentin using a MIR tunable nanosecond pulsed laser...
  25. doi Development of a tandem time-of-flight mass spectrometer with an electrospray ionization ion source
    Hirofumi Nagao
    Renovation Center of Instruments for Science Education and Technology, Osaka University, 1 1 Machikaneyama, Toyonaka, Osaka 560 0043, Japan
    J Mass Spectrom 45:937-43. 2010
    ..It was demonstrated that high-energy CID of multiply protonated peptides could be achieved in the ESI-TOF/quadTOF...
  26. ncbi Prevention of dental caries in partially erupted permanent teeth with a CO2 laser
    Junji Kato
    Developmental Oral Health Science, Department of Orofacial Development and Function, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Clin Laser Med Surg 21:369-74. 2003
    ..The purpose of this study was to determine the effect of CO2 laser irradiation in the prevention of pit and fissure caries in immature molars with covering opercula...