Yasuyuki Okuma

Summary

Country: Japan

Publications

  1. ncbi request reprint Reciprocal Ia inhibition in patients with asymmetric spinal spasticity
    Yasuyuki Okuma
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    Clin Neurophysiol 113:292-7. 2002
  2. doi request reprint The clinical spectrum of freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Mov Disord 23:S426-30. 2008
  3. ncbi request reprint Freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    J Neurol 253:VII27-32. 2006
  4. ncbi request reprint Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2)
    Yasuyuki Okuma
    Department of Neurology, Juntendo Izu Nagaoka Hospital, 1129 Nagaoka, Izu Nagaoka, Tagata, 94089, Shizuoka 94089, Japan
    Parkinsonism Relat Disord 9:313-4. 2003
  5. ncbi request reprint Myoclonic tremulous movements in multiple system atrophy are a form of cortical myoclonus
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, Shizuoka, Japan
    Mov Disord 20:451-6. 2005
  6. doi request reprint Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    Mov Disord 24:1977-83. 2009
  7. doi request reprint Correlation between depressive symptoms and nocturnal disturbances in Japanese patients with Parkinson's disease
    Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321 0293, Japan
    Parkinsonism Relat Disord 15:15-9. 2009
  8. doi request reprint Excessive daytime sleepiness and sleep episodes in Japanese patients with Parkinson's disease
    Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321 0293, Japan
    J Neurol Sci 271:47-52. 2008
  9. doi request reprint Cerebral infarcts associated with adenomyosis among middle-aged women
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokunishi, Shizuoka, Japan
    J Stroke Cerebrovasc Dis 21:910.e1-5. 2012
  10. doi request reprint Gradient echo T2*-weighted magnetic resonance imaging revealing cerebral microbleeds in a patient with microscopic polyangiitis complicated by cerebrovascular disease
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokunishi, Shizuoka, Japan
    J Stroke Cerebrovasc Dis 21:904.e7-9. 2012

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Reciprocal Ia inhibition in patients with asymmetric spinal spasticity
    Yasuyuki Okuma
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    Clin Neurophysiol 113:292-7. 2002
    ..The purpose of the present study was to establish a correlation between Ia inhibition and clinical abnormalities in spasticity following a spinal cord injury (SCI)...
  2. doi request reprint The clinical spectrum of freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Mov Disord 23:S426-30. 2008
    ..Careful observation and gait pattern analysis may lead to a successful management of individual PD patients with FOG...
  3. ncbi request reprint Freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    J Neurol 253:VII27-32. 2006
    ..Deep brain stimulation of the STN often alleviates FOG in the "off" state...
  4. ncbi request reprint Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2)
    Yasuyuki Okuma
    Department of Neurology, Juntendo Izu Nagaoka Hospital, 1129 Nagaoka, Izu Nagaoka, Tagata, 94089, Shizuoka 94089, Japan
    Parkinsonism Relat Disord 9:313-4. 2003
    ..We suggest that peripheral neuropathy may occur in patients with advanced ARJP due to the loss of parkin protein function, although the function of parkin in the peripheral nervous system remains to be clarified...
  5. ncbi request reprint Myoclonic tremulous movements in multiple system atrophy are a form of cortical myoclonus
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, Shizuoka, Japan
    Mov Disord 20:451-6. 2005
    ..A jerk-locked averaging technique revealed premyoclonic cortical potentials in 9 patients. These findings suggest that small-amplitude myoclonic movements in MSA are a form of cortical myoclonus...
  6. doi request reprint Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    Mov Disord 24:1977-83. 2009
    ..Since fatigue is significantly related to QOL reduction, therapeutic interventions including treatment of sleep disturbance are important...
  7. doi request reprint Correlation between depressive symptoms and nocturnal disturbances in Japanese patients with Parkinson's disease
    Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321 0293, Japan
    Parkinsonism Relat Disord 15:15-9. 2009
    ....
  8. doi request reprint Excessive daytime sleepiness and sleep episodes in Japanese patients with Parkinson's disease
    Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi 321 0293, Japan
    J Neurol Sci 271:47-52. 2008
    ..ESS score of >or=10 had 75% sensitivity and 82.4% specificity for sleep episodes. These results suggest that sleepiness in PD is dependent on disease itself and dopaminergic treatment rather than nocturnal disturbances...
  9. doi request reprint Cerebral infarcts associated with adenomyosis among middle-aged women
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokunishi, Shizuoka, Japan
    J Stroke Cerebrovasc Dis 21:910.e1-5. 2012
    ....
  10. doi request reprint Gradient echo T2*-weighted magnetic resonance imaging revealing cerebral microbleeds in a patient with microscopic polyangiitis complicated by cerebrovascular disease
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokunishi, Shizuoka, Japan
    J Stroke Cerebrovasc Dis 21:904.e7-9. 2012
    ..Brain MRIs, including gradient echo T2-weighted imaging, should be performed on patients diagnosed as or suspected of having MPA to assess the risk of cerebral hemorrhage...
  11. doi request reprint Anti-aquaporin-4 antibody-positive definite neuromyelitis optica in a patient with thymectomy for myasthenia gravis
    Kotaro Ogaki
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokuni, Japan
    Neurologist 18:76-9. 2012
    ..Recently, a rare coexistence of NMO and myasthenia gravis (MG) has been documented. Here, we provide further evidence of the association of these 2 immunologic disorders and review the literature...
  12. ncbi request reprint Successful treatment of relapsing neuro-Sweet's disease with corticosteroid and dapsone combination therapy
    Jiro Fukae
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    Clin Neurol Neurosurg 109:910-3. 2007
    ..Dapsone should be considered as a therapeutic option for neuro-Sweet's disease patients showing relapse...
  13. ncbi request reprint Segmental zoster paresis of limbs: report of three cases and review of literature
    Sumihiro Kawajiri
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Neurologist 13:313-7. 2007
    ..Awareness of this disorder is important because it may eliminate unnecessary invasive investigations and lead to appropriate treatment. Further studies on the treatment are necessary...
  14. ncbi request reprint Reversible cerebral vasoconstriction syndrome presenting as subarachnoid hemorrhage, reversible posterior leukoencephalopathy, and cerebral infarction
    Kazuyuki Noda
    Department of Neurology, Juntendo University Shizuoka Hospital, Japan
    Intern Med 50:1227-33. 2011
    ..Her various complications are due to the responsible vasoconstriction that started distally and progressed towards proximal arteries. This case demonstrates the spectrum of presentations of RCVS, a clinically complicated condition...
  15. ncbi request reprint Possible neuro-Sweet disease mimicking brain tumor in the medulla oblongata--case report
    Chihiro Akiba
    Department of Neurosurgery, Juntendo University Shizuoka Hospital, Izunokuni, Shizuoka, Japan
    Neurol Med Chir (Tokyo) 51:140-3. 2011
    ..Steroid pulse therapy was started after surgery and the clinical symptoms improved. Neurosurgeons should be aware of inflammatory disorders such as NSD mimicking brain tumor...
  16. ncbi request reprint Reversible focal cerebral cortical lesions in a patient with heat stroke
    Atsuhito Fuse
    Department of Neurology, Juntendo University Shizuoka Hospital, Japan
    Intern Med 52:377-80. 2013
    ..Although the cerebellum is most susceptible to lesion formation, the mechanisms underlying heat stroke are multifactorial and may result in a variety of brain lesions...
  17. doi request reprint Cerebral infarction developing in a patient without cancer with a markedly elevated level of mucinous tumor marker
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    J Stroke Cerebrovasc Dis 21:619.e1-2. 2012
    ..The CA125 and the D-dimer levels became normal after treatment of adenomyosis. Our findings suggest for the first time that marked elevation of mucinous tumor marker level may cause cerebral infarction even in benign conditions...
  18. pmc How far do the complaints of patients with Parkinson's disease reflect motor fluctuation? Quantitative analysis using a portable gait rhythmogram
    Hiroya Utsumi
    Department of Neurology, Tokyo Medical University, Tokyo 160 0023, Japan
    ISRN Neurol 2012:372030. 2012
    ..This discrepancy suggests that the objective continuous recording of the cadence and acceleration is necessary to understand motor fluctuation...
  19. ncbi request reprint Characteristics of sleep disturbances in Japanese patients with Parkinson's disease. A study using Parkinson's disease sleep scale
    Keisuke Suzuki
    Department of Neurology, Dokkyo Medical University, Tochigi, Japan
    Mov Disord 22:1245-51. 2007
    ..We speculate that the reduction of neurotransmitters involved in the sleep-wakefulness mechanism and degeneration of neurons progress together in parallel with deterioration of motor function...
  20. ncbi request reprint [A case of neuralgic amyotrophy in the lower extremity (lumbosacral radiculoplexus neuropathy)]
    Yukiko Takata
    Department of Neurology, Juntendo University Shizuoka Hospital, Nagaoka, Izunokuni shi, Shizuoka, Japan
    Brain Nerve 59:435-8. 2007
    ..Neuralgic amyotrophy in the lower extremities is rare, but awareness of this disorder helps us avoid unnecessary surgical investigations and leads to possible treatment with immunomodulative therapy...
  21. ncbi request reprint Cortical myoclonus due to hypocalcemia 12 years after thyroidectomy
    Yuji Ueno
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, 1129 Nagaoka, Tagata gun, Shizuoka 410 2295, Japan
    Clin Neurol Neurosurg 108:400-3. 2006
    ..The myoclonic state disappeared as serum calcium level became normal. Hypocalcemia should be considered in patients who had had a thyroidectomy, even if it was performed more than 10 years previously...
  22. ncbi request reprint [Familial amyotrophic lateral sclerosis with rapid progression]
    Genko Oyama
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni shi, Shizuoka 410 2295, Japan
    No To Shinkei 57:1003-6. 2005
    ..Autosomal dominant amyotrophic lateral sclerosis (AD-ALS) was considered, but SOD1 gene mutation was not detected. The present pedigree may have familial ALS caused by a gene mutation other than SOD1...
  23. ncbi request reprint Evaluation of the efficacy of pramipexole for treating levodopa-induced dyskinesia in patients with Parkinson's disease
    Hiroya Utsumi
    Department of Neurology, Tokyo Medical University, Japan
    Intern Med 52:325-32. 2013
    ..g., levodopa-induced dyskinesia, LID). We hypothesized that a non-ergot dopamine agonist with strong affinity for D3) dopamine receptors (pramipexole) may improve LID in patients taking an ergot D1/D2 dopamine agonist...
  24. pmc Deficits in scaling of gait force and cycle in parkinsonian gait identified by long-term monitoring of acceleration with the portable gait rhythmogram
    Hiroo Terashi
    Department of Neurology, Tokyo Medical University, Tokyo 160 0023, Japan
    ISRN Neurol 2012:306816. 2012
    ..The range of change in gait cycle was less than 75% in 8 patients. The range of changes in both parameters was less than 75% in 4 patients. The results suggest narrow changes in gait parameters in PD...
  25. pmc Convulsive movements in bilateral paramedian thalamic and midbrain infarction
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Case Rep Neurol 3:289-93. 2011
    ..Physicians should recognize this condition, because not only seizure control but also early management of ischemic stroke is required...
  26. ncbi request reprint Blurred vision with acute hypertension indicating hypertensive brainstem encephalopathy-case report-
    Kotaro Ogaki
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokuni, Shizuoka, Japan
    Neurol Med Chir (Tokyo) 49:625-30. 2009
    ..Clinicians should consider HBE in hypertensive patients with blurred vision. HBE is reversible if immediate antihypertensive treatment is initiated, but neurological sequelae may develop if treatment is delayed...
  27. ncbi request reprint [Cryptococcal meningitis successfully treated with liposomal amphotericin B and voriconazole in an elderly patient]
    Kotaro Ogaki
    Department of Neurology, Juntendo University School of Medicine, Izunokuni shi, Shizuoka, Japan
    Brain Nerve 62:1337-40. 2010
    ..The recovery of our patient indicates that the administration of L-AMB and VRCZ to elderly patients with cryptococcal meningitis and renal insufficiency is safe and leads to a successful outcome...
  28. ncbi request reprint Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature
    Momo Tani
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka
    Intern Med 46:1597-600. 2007
    ..There were no symptoms or signs associated with the lesion, and the prognosis was good. Although rare in adult patients, awareness of a reversible splenial lesion in meningoencephalitis is important...
  29. ncbi request reprint Isolated proximal leg paresis due to a small cortical infarction
    Kazuyuki Noda
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunokuni
    Intern Med 49:1633-6. 2010
    ..It is clinically important to pay close attention to the contralateral top of the motor cortex when examining pure motor monoparesis of a proximal part of a lower extremity...
  30. doi request reprint Bilateral facial nerve palsy due to otitis media associated with myeloperoxidase-antineutrophil cytoplasmic antibody
    Akio Mori
    Departments of Neurology AM, TH, S IK, Ko, NK and Nephrology HS, IO, Juntendo University School of Medicine, Tokyo, Japan and Department of Neurology K IH, YO, KH, KN, Juntendo Shizuoka Hospital, Tokyo, Japan
    Am J Med Sci 346:240-3. 2013
    ..In both the patients, treatment with prednisolone and immune-suppressant drugs resulted in an improvement of OM and cranial polyneuropathy. Physicians should be aware that MPO-ANCA-positive OM can cause bilateral facial nerve palsy. ..
  31. ncbi request reprint Bilateral hypoglossal nerve involvement in chronic inflammatory demyelinating polyneuropathy
    Kazuo Yamashiro
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, Shizuoka, Japan
    Eur Neurol 51:45-6. 2004
  32. ncbi request reprint Isolated deep cerebral venous thrombosis: an important cause for isolated mental impairment
    Terubumi Watanabe
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, Shizuoka, Japan
    Eur Neurol 52:123-5. 2004
  33. doi request reprint Prevalence of abnormal glucose metabolism and insulin resistance among subtypes of ischemic stroke in Japanese patients
    Takao Urabe
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    Stroke 40:1289-95. 2009
    ..The purpose was to assess the prevalence of disorders of glucose metabolism and insulin resistance in Japanese ischemic stroke patients with no history of diabetes by performing 75-gram oral glucose tolerance test (OGTT)...
  34. ncbi request reprint Subacute longitudinal myelitis associated with Behcet's disease
    Jiro Fukae
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka
    Intern Med 49:343-7. 2010
    ..Longitudinal myelitis involving the entire spinal cord, as seen in our patient, has never been described before. This case suggests that NBD could be one of the important differential diagnoses of longitudinal myelitis...
  35. ncbi request reprint Blepharospasm associated with multiple system atrophy: a case report and review of the literature
    Maki Kagohashi
    Department of Neurology, Juntendo University Izu Nagaoka Hospital, 1129 Nagaoka, Izu Nagaoka, Tagata, Shizuoka 410 2295, Japan
    Parkinsonism Relat Disord 10:169-71. 2004
    ..Recognition of blepharospasm in MSA patients is important, as blepharospasm is a treatable feature in this otherwise intractable disorder...
  36. ncbi request reprint Pseudoathetosis caused by migrated cervical disc
    Takeo Arai
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Parkinsonism Relat Disord 13:59-61. 2007
    ..Migrated cervical disc should be considered in patients with a profound sensory loss and pseudoathetosis in the hands, because this condition is treatable...
  37. ncbi request reprint [Amyotrophic lateral sclerosis presented with alexia of kanji and word meaning aphasia]
    Atsuko Iroi
    Department of Neurology, Juntendo Izu Nagaoka Hospital, 1129 Nagaoka, Izu Nagaoka, Tagata gun, Shizuoka 410 2295, Japan
    No To Shinkei 54:903-7. 2002
    ..Our patient appeared to meet the clinical criteria for frontotemporal degeneration of motor neuron disease type, and is the first case of amyotrophic lateral sclerosis showing alexia of kanji and word meaning aphasia...
  38. ncbi request reprint [Fatigue and weight loss in Parkinson's disease]
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, Izunoknuishi, Shizuoka, Japan
    Brain Nerve 64:384-93. 2012
    ..Because low body weight is associated with negative health effects and a poor prognosis, monitoring weight and nutritional status should be part of PD management...
  39. ncbi request reprint Quantitative assessment of gait bradykinesia in Parkinson's disease using a portable gait rhythmogram
    Hiroya Utsumi
    Department of Neurology, Tokyo Medical University, Shinjuku ku, Japan
    Acta Med Okayama 66:31-40. 2012
    ..e., a range of floor reaction forces. The results suggest that assessment of the combination of changes in gait cycle and gait acceleration can quantitatively define the severity of gait bradykinesia...
  40. ncbi request reprint [Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment]
    Tomoyoshi Kondo
    Department of Neurology, Juntendo University School of Medicine, Japan
    No To Shinkei 54:1041-8. 2002
    ..This study may assure tolerability of selegiline hydrochloride in a long-term treatment of Parkinson's disease patients...
  41. ncbi request reprint [A case of brachial plexus neuropathy who presented with acute paralysis of the hand after sleep]
    Makiko Iijima
    Department of Neurology, Juntendo Izu Nagaoka Hospital, 1129 Nagaoka, Izu Nagaoka, Tagata gun, Shizuoka 410 2295, Japan
    No To Shinkei 54:819-22. 2002
    ..Our patient suggests that brachial plexus neuropathy should be considered in the acute paresis of the hand after sleep, and that surgical procedure would lead to a successful outcome...
  42. ncbi request reprint [A guideline for the treatment of Parkinson's disease]
    Yoshikuni Miziuno
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    Rinsho Shinkeigaku 42:421-94. 2002
  43. ncbi request reprint Contrasting genotypes of the tau gene in two phenotypically distinct patients with P301L mutation of frontotemporal dementia and parkinsonism linked to chromosome 17
    Tomonori Kobayashi
    Department of Neurology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    J Neurol 249:669-75. 2002
    ..Accumulation of information as to phenotype-genotype association will settle this hypothesis...
  44. ncbi request reprint An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome
    Kenya Nishioka
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Inzunokuni, Shizuoka 410 2295, Japan
    Clin Neurol Neurosurg 108:772-4. 2006
    ..The improvement of facial palsy and swallowing difficulty was delayed. VZV infection should be considered even in patients who show unilateral multiple cranial neuropathy mimicking Garcin syndrome because it is treatable...