Yoshitaka Takahashi

Summary

Affiliation: Okayama Prefectural University
Country: Japan

Publications

  1. request reprint
    Takahashi Y, Zhu H, Xu W, Murakami T, Iwasaki T, Hattori H, et al. Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase. Biochem Biophys Res Commun. 2005;338:128-35 pubmed
    ..These results strongly suggest that LRP contributes to the LDL oxidation by 12/15-LOX in macrophages by selective uptake and efflux of cholesteryl ester in the LDL particle. ..
  2. Kawakami Y, Kinoshita M, Mori Y, Okochi S, Hirano S, Shimoda I, et al. The Y54(L)W mutation of anti-leukotriene C4 single-chain antibody increases affinity to leukotriene E4. J Biochem. 2017;161:79-86 pubmed publisher
    ..The results may provide an insight into the molecular basis of specific LT recognition by the antibody. ..
  3. Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki Yamamoto T, Suzuki M, et al. Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies. Biochim Biophys Acta. 2014;1840:1625-33 pubmed publisher
    ..mAbLTC can be used in the treatment of inflammatory diseases such as asthma. ..

Locale

Detail Information

Publications3

  1. request reprint
    Takahashi Y, Zhu H, Xu W, Murakami T, Iwasaki T, Hattori H, et al. Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase. Biochem Biophys Res Commun. 2005;338:128-35 pubmed
    ..These results strongly suggest that LRP contributes to the LDL oxidation by 12/15-LOX in macrophages by selective uptake and efflux of cholesteryl ester in the LDL particle. ..
  2. Kawakami Y, Kinoshita M, Mori Y, Okochi S, Hirano S, Shimoda I, et al. The Y54(L)W mutation of anti-leukotriene C4 single-chain antibody increases affinity to leukotriene E4. J Biochem. 2017;161:79-86 pubmed publisher
    ..The results may provide an insight into the molecular basis of specific LT recognition by the antibody. ..
  3. Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki Yamamoto T, Suzuki M, et al. Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies. Biochim Biophys Acta. 2014;1840:1625-33 pubmed publisher
    ..mAbLTC can be used in the treatment of inflammatory diseases such as asthma. ..