Ken Ei Sada

Summary

Affiliation: Okayama University
Country: Japan

Publications

  1. pmc Current status of the treatment of microscopic polyangiitis and granulomatosis with polyangiitis in Japan
    Koichi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kita ku, Okayama 700 8558, Japan
    Clin Exp Nephrol 17:51-8. 2013
  2. pmc Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
    Tomoko Kawabata
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan
    Arthritis Res Ther 12:R133. 2010
  3. ncbi request reprint Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Rheumatol 33:1545-52. 2006
  4. doi request reprint Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α
    Mariko Takano
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Mol Cell Endocrinol 348:224-32. 2012
  5. ncbi request reprint Evaluation of weekly-reduction regimen of glucocorticoids in combination with cyclophosphamide for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis in Japanese patients
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kitaku, Okayama City 700 8558, Japan
    Rheumatol Int 32:2999-3005. 2012
  6. ncbi request reprint Risk factors for infection in patients with remitted rheumatic diseases treated with glucocorticoids
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Acta Med Okayama 65:329-34. 2011
  7. doi request reprint Estrogen facilitates osteoblast differentiation by upregulating bone morphogenetic protein-4 signaling
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Steroids 78:513-20. 2013
  8. doi request reprint Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-alpha in C2C12 cells
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kitaku, Okayama 700 8558, Japan
    Mol Cell Endocrinol 325:118-27. 2010
  9. ncbi request reprint Clinical usefulness of a prognostic score in histological analysis of renal biopsy in patients with lupus nephritis
    Shoichiro Kojo
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama City, Okayama, 700 8558, Japan
    J Rheumatol 36:2218-23. 2009
  10. ncbi request reprint Rapid progression of Graves' ophthalmopathy despite the administration of thiamazole
    Takayuki Katsuyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    Intern Med 52:2317-20. 2013

Collaborators

  • Hirofumi Makino
  • Fumio Otsuka
  • Yohei Maeshima
  • Hitoshi Sugiyama
  • Kentaro Inoue
  • Takao Saito
  • Akira Matsunaga
  • Jun Wada
  • Masahiro Yamamura
  • Ritei Uehara
  • Yoshinori Matsumoto
  • Mariko Takano
  • Takayuki Katsuyama
  • Koichi Sugiyama
  • Kenichi Inagaki
  • Tomoko Kawabata
  • Eri Nakamura
  • Masaya Takeda
  • Hiroshi Wakabayashi
  • Ryutaro Yamanaka
  • Kishio Toma
  • Naoko Tsukamoto
  • Noriko Toyota
  • Tomoko Miyoshi
  • Misuzu Yamashita
  • Tomoyuki Mukai
  • Shoichiro Kojo
  • Masaru Kinomura
  • Daisho Hirota
  • Haruhito Adam Uchida
  • Yoshinobu Maeda
  • Ryoko Umebayashi
  • Toshio Ogura
  • Mariko Takano-Narazaki
  • Michiko Kurosawa
  • Yukari Mimura
  • Koji Takasugi
  • Keiichiro Nishida
  • Hiroyuki Otani
  • Junko Inagaki
  • Satoshi Hirohata
  • Yasutaka Kadota
  • Hiroko Ogawa
  • Yoshifumi Ninomiya
  • Mizuho Kobayashi
  • Mie Maruyama
  • Hiroyuki Yanai
  • Yuki Takazawa
  • Motoko Kanzaki

Detail Information

Publications17

  1. pmc Current status of the treatment of microscopic polyangiitis and granulomatosis with polyangiitis in Japan
    Koichi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kita ku, Okayama 700 8558, Japan
    Clin Exp Nephrol 17:51-8. 2013
    ..This study aimed to describe the epidemiologic characteristics of microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) in Japan...
  2. pmc Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
    Tomoko Kawabata
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan
    Arthritis Res Ther 12:R133. 2010
    ....
  3. ncbi request reprint Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Rheumatol 33:1545-52. 2006
    ..We evaluated IR in association with plasma concentrations of adipocytokines in patients with SLE...
  4. doi request reprint Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α
    Mariko Takano
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Mol Cell Endocrinol 348:224-32. 2012
    ..Collectively, our present data establishes that PPAR activities are functionally involved in modulating the interaction between the BMP system and TNF-α receptor signaling that is crucial for bone metabolism...
  5. ncbi request reprint Evaluation of weekly-reduction regimen of glucocorticoids in combination with cyclophosphamide for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis in Japanese patients
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kitaku, Okayama City 700 8558, Japan
    Rheumatol Int 32:2999-3005. 2012
    ..017), compared with those treated with the monthly-reduction regimen. A therapeutic strategy using the weekly-reduction regimen of GCs would be effective and would have fewer side effects than the monthly-reduction regimen...
  6. ncbi request reprint Risk factors for infection in patients with remitted rheumatic diseases treated with glucocorticoids
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Acta Med Okayama 65:329-34. 2011
    ..65 to 14.44) by the Cox proportional hazard model. Even after achievement of clinical remission, careful observation is needed for patients with interstitial pneumonia, more so than for those receiving high-dose glucocorticoids...
  7. doi request reprint Estrogen facilitates osteoblast differentiation by upregulating bone morphogenetic protein-4 signaling
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Steroids 78:513-20. 2013
    ..Thus, estrogen is functionally involved in the process of osteoblast differentiation regulated by BMP-4 through upregulating BMP sensitivity of MC3T3-E1 cells...
  8. doi request reprint Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-alpha in C2C12 cells
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kitaku, Okayama 700 8558, Japan
    Mol Cell Endocrinol 325:118-27. 2010
    ..BMP-2 increases the sensitivities of ERs and GCR, whereas estrogen and glucocorticoid differentially regulate BMP-Smad and TNF-alpha signaling...
  9. ncbi request reprint Clinical usefulness of a prognostic score in histological analysis of renal biopsy in patients with lupus nephritis
    Shoichiro Kojo
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama City, Okayama, 700 8558, Japan
    J Rheumatol 36:2218-23. 2009
    ..To evaluate active and chronic lesions in association with renal outcome according to the International Society of Nephrology/Renal Pathology Society classification in patients with lupus nephritis...
  10. ncbi request reprint Rapid progression of Graves' ophthalmopathy despite the administration of thiamazole
    Takayuki Katsuyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    Intern Med 52:2317-20. 2013
    ..Although the mechanism of the progression of Graves' ophthalmopathy has not yet been elucidated, special attention should be paid to the occurrence of ophthalmopathy even after the initiation of thiamazole therapy. ..
  11. ncbi request reprint Systemic lupus erythematosus complicated with acute myocardial infarction and ischemic colitis
    Yoshinori Matsumoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Intern Med 50:2669-73. 2011
    ..This is the first report of SLE accompanying AMI, ischemic colitis and perforation of the digestive tract possibly due to SLE vasculitis, which was dramatically improved by treatment with high-dose glucocorticoid...
  12. ncbi request reprint A novel variant apolipoprotein E Okayama in a patient with lipoprotein glomerulopathy
    Masaru Kinomura
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Nephrol Dial Transplant 23:751-6. 2008
  13. ncbi request reprint Large vessel vasculitis with myelodysplastic syndrome
    Takayuki Katsuyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Intern Med 53:63-6. 2014
    ..Our case suggests that the association between systemic vasculitis and MDS may result in poor outcomes. ..
  14. ncbi request reprint A nationwide survey on the epidemiology and clinical features of eosinophilic granulomatosis with polyangiitis (Churg-Strauss) in Japan
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Mod Rheumatol 24:640-4. 2014
    ..However, female predominance and a high frequency of neurological manifestations characterized Japanese patients. ..
  15. doi request reprint Unique microstructures and podocytic infolding in glomerular basement membrane associated with collagen diseases: a report of three cases
    Hitoshi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan
    Clin Exp Nephrol 12:450-4. 2008
    ..The response to glucocorticoid therapy was favorable in two cases. The cause of these morphological changes in the GBM might be associated with autoimmune disorders...
  16. pmc Usefulness of ISN/RPS classification of lupus nephritis
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan
    J Korean Med Sci 24:S7-10. 2009
    ..Both were similarly observed in IV-G and IV-S. The more qualitative categorization by the response to standard treatment may be needed to emphasize clinically relevant lesion related to renal outcome...
  17. doi request reprint Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling
    Misuzu Yamashita
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kitaku, Okayama City, 700 8558, Japan
    Regul Pept 162:99-108. 2010
    ..Collectively, our data show that simvastatin inhibits osteoclastic differentiation through inhibiting Src as well as enhancing MAPK/AKT pathways...