Toru Miyoshi

Summary

Affiliation: Okayama University
Country: Japan

Publications

  1. ncbi Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non- diabetic subjects: a preliminary report
    Yoko Noda
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Cardiovasc Diabetol 12:8. 2013
  2. ncbi Elevated serum adipocyte fatty acid-binding protein concentrations are independently associated with renal dysfunction in patients with stable angina pectoris
    Mutsumi Iwamoto
    Department of Cardiology, Kagawa Prefectural Central Hospital, Kagawa, Japan
    Cardiovasc Diabetol 11:26. 2012
  3. ncbi Serum adipocyte fatty acid-binding protein is independently associated with coronary atherosclerotic burden measured by intravascular ultrasound
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1, Shikata cho, Okayama 700 8558, Japan
    Atherosclerosis 211:164-9. 2010
  4. ncbi Cardio-ankle vascular index is independently associated with the severity of coronary atherosclerosis and left ventricular function in patients with ischemic heart disease
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Atheroscler Thromb 17:249-58. 2010
  5. ncbi Olmesartan reduces arterial stiffness and serum adipocyte fatty acid-binding protein in hypertensive patients
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Heart Vessels 26:408-13. 2011
  6. ncbi Impact of olmesartan on progression of coronary atherosclerosis a serial volumetric intravascular ultrasound analysis from the OLIVUS (impact of OLmesarten on progression of coronary atherosclerosis: evaluation by intravascular ultrasound) trial
    Atsushi Hirohata
    Sakakibara Heart Institute of Okayama, Okayama, Japan
    J Am Coll Cardiol 55:976-82. 2010
  7. ncbi Association of increased plasma adipocyte fatty acid-binding protein with coronary artery disease in non-elderly men
    Masayuki Doi
    Department of Cardiology, Kagawa Prefectural Central Hospital, Kagawa, Japan
    Cardiovasc Diabetol 10:44. 2011
  8. ncbi Connective tissue growth factor induction in a pressure-overloaded heart ameliorated by the angiotensin II type 1 receptor blocker olmesartan
    Mutsumi Iwamoto
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita ku, Okayama, Japan
    Hypertens Res 33:1305-11. 2010
  9. ncbi Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients
    Masayuki Doi
    Department of Cardiology, Kagawa Prefectural Central Hospital, Takamatsu, Japan
    Am J Med Sci 339:433-9. 2010
  10. ncbi Intermittent arm ischemia induces vasodilatation of the contralateral upper limb
    Kenki Enko
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kita ku, Okayama, 700 8558, Japan
    J Physiol Sci 61:507-13. 2011

Collaborators

Detail Information

Publications34

  1. ncbi Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non- diabetic subjects: a preliminary report
    Yoko Noda
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Cardiovasc Diabetol 12:8. 2013
    ..abstract:..
  2. ncbi Elevated serum adipocyte fatty acid-binding protein concentrations are independently associated with renal dysfunction in patients with stable angina pectoris
    Mutsumi Iwamoto
    Department of Cardiology, Kagawa Prefectural Central Hospital, Kagawa, Japan
    Cardiovasc Diabetol 11:26. 2012
    ..Adipocyte fatty acid-binding protein (A-FABP) plays an important role in atherosclerosis. We investigated whether plasma A-FABP is involved in renal function in patients with stable angina pectoris...
  3. ncbi Serum adipocyte fatty acid-binding protein is independently associated with coronary atherosclerotic burden measured by intravascular ultrasound
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1, Shikata cho, Okayama 700 8558, Japan
    Atherosclerosis 211:164-9. 2010
    ..We therefore investigated the association between the serum A-FABP level and coronary atherosclerosis...
  4. ncbi Cardio-ankle vascular index is independently associated with the severity of coronary atherosclerosis and left ventricular function in patients with ischemic heart disease
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Atheroscler Thromb 17:249-58. 2010
    ..We investigated the association of the CAVI with coronary atherosclerosis and left ventricular (LV) systolic and diastolic function in patients with ischemic heart disease (IHD)...
  5. ncbi Olmesartan reduces arterial stiffness and serum adipocyte fatty acid-binding protein in hypertensive patients
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Heart Vessels 26:408-13. 2011
    ..Olmesartan ameliorated arterial stiffness in patients with hypertension, which may be involved in the reduction of serum A-FABP...
  6. ncbi Impact of olmesartan on progression of coronary atherosclerosis a serial volumetric intravascular ultrasound analysis from the OLIVUS (impact of OLmesarten on progression of coronary atherosclerosis: evaluation by intravascular ultrasound) trial
    Atsushi Hirohata
    Sakakibara Heart Institute of Okayama, Okayama, Japan
    J Am Coll Cardiol 55:976-82. 2010
    ..The aim of this study was to evaluate the impact of olmesartan on progression of coronary atherosclerosis...
  7. ncbi Association of increased plasma adipocyte fatty acid-binding protein with coronary artery disease in non-elderly men
    Masayuki Doi
    Department of Cardiology, Kagawa Prefectural Central Hospital, Kagawa, Japan
    Cardiovasc Diabetol 10:44. 2011
    ..We investigated whether an increased in plasma A-FABP level can be independently associated with the presence of coronary artery disease (CAD)...
  8. ncbi Connective tissue growth factor induction in a pressure-overloaded heart ameliorated by the angiotensin II type 1 receptor blocker olmesartan
    Mutsumi Iwamoto
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita ku, Okayama, Japan
    Hypertens Res 33:1305-11. 2010
    ..Our results provide insight into the beneficial effects of olmesartan on PO hearts, independent of blood-pressure lowering...
  9. ncbi Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients
    Masayuki Doi
    Department of Cardiology, Kagawa Prefectural Central Hospital, Takamatsu, Japan
    Am J Med Sci 339:433-9. 2010
    ..We investigated the effect of a calcium channel blocker or a diuretic added to angiotensin II receptor blockers (ARBs) on the augmentation index (AI), as a marker of arterial stiffness and wave reflection, in hypertensive patients...
  10. ncbi Intermittent arm ischemia induces vasodilatation of the contralateral upper limb
    Kenki Enko
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Kita ku, Okayama, 700 8558, Japan
    J Physiol Sci 61:507-13. 2011
    ..02). Intermittent arm ischemia was accompanied by vasodilatation of another artery and enhancement of parasympathetic activity. Those effects may play an important role in the mechanism of RIPC...
  11. ncbi Thrombospondin-1 is induced in rat myocardial infarction and its induction is accelerated by ischemia/reperfusion
    Satoshi Sezaki
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Exp Biol Med (Maywood) 230:621-30. 2005
    ..Thus, the immediate and marked increase of TSP-1 expression suggests that TSP-1 has an inflammatory-associated role in MI...
  12. ncbi Ezetimibe improves postprandial hyperlipemia and its induced endothelial dysfunction
    Kei Yunoki
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, 2 5 1, Shikata cho, Kita ku, Okayama 700 8558, Japan
    Atherosclerosis 217:486-91. 2011
    ..We investigated the association between postprandial lipid profiles and endothelial function, and we examined the effects of ezetimibe on postprandial hyperlipemia and lipemia-induced endothelial dysfunction...
  13. ncbi Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis
    Masanari Obika
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    Cancer Sci 103:1889-97. 2012
    ..Collectively, our results demonstrated that ADAMTS1 gene transfer inhibited angiogenesis in vitro and in vivo, likely as a result of the induction of endothelial cell apoptosis by ADAMTS1 that occurs independent of the protease activity...
  14. ncbi Effect of cilnidipine on normal to marginally elevated urine albumin-creatinine ratio in asymptomatic non-diabetic hypertensive patients: an exponential decay curve analysis
    Takaaki Nakatsu
    Department of Cardiology, Kagawa ken Saiseikai Hospital, Takamatsu, Japan
    Clin Drug Investig 30:699-706. 2010
    ..High-normal urinary albumin excretion has been reported to have clinical significance with respect to progression of proteinuria and hypertension...
  15. ncbi Significant relationship between changes in brachial-ankle pulse wave velocity relative to blood pressure elevation and coronary artery disease
    Issei Komatsubara
    Department of Cardiology, Tsuyama General Hospital, Japan
    Coron Artery Dis 21:407-13. 2010
    ....
  16. ncbi ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells
    Omer F Hatipoglu
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    J Biol Chem 284:16325-33. 2009
    ..In summary, we found that ADAMTS1 is transiently induced by hypoxia in endothelial cells, and its transcription is mediated by HIF-1 binding. Our data indicate that ADAMTS1 is a novel acute hypoxia-inducible gene...
  17. ncbi Association of serum levels of arachidonic acid and eicosapentaenoic acid with prevalence of major adverse cardiac events after acute myocardial infarction
    Masayuki Ueeda
    Department of Cardiovascular Medicine, Mitoyo General Hospital, Kagawa, 769 1695, Japan
    Heart Vessels 26:145-52. 2011
    ..The present study warrants further studies involving a large number of patients to confirm that the serum levels of these fatty acids and their ratios are predictors of MACE after AMI...
  18. ncbi Serum interferon-gamma-inducible protein 10 level was increased in myocardial infarction patients, and negatively correlated with infarct size
    Kazuya Koten
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700 8558, Japan
    Clin Biochem 41:30-7. 2008
    ..We examined the serum levels of interferon-gamma-inducible protein 10 (IP-10), an inflammation-induced chemokine, in acute myocardial infarction (AMI)...
  19. ncbi Association of new arterial stiffness parameter, the cardio-ankle vascular index, with left ventricular diastolic function
    Kosuke Sakane
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Atheroscler Thromb 15:261-8. 2008
    ..In this study, we analyzed the relationship between CAVI and left ventricular (LV) diastolic dysfunction...
  20. ncbi AHR, a novel acute hypoxia-response sequence, drives reporter gene expression under hypoxia in vitro and in vivo
    Mehmet Zeynel Cilek
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Cell Biol Int 35:1-8. 2011
    ..In summary, we have demonstrated that the AHR system induced the reporter gene expression by acute hypoxia, and its induction is transient. This is the first report showing the unique acute hypoxia-activated gene expression system...
  21. ncbi Type IV collagen induces expression of thrombospondin-1 that is mediated by integrin alpha1beta1 in astrocytes
    Tomoko Yonezawa
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan
    Glia 58:755-67. 2010
    ..Collectively, our results suggest that vascular basement membrane components substantially impact gene expression in astrocytes during brain tissue repair...
  22. ncbi Relationship between activin A level and infarct size in patients with acute myocardial infarction undergoing successful primary coronary intervention
    Toru Miyoshi
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Clin Chim Acta 401:3-7. 2009
    ..We examined the serum level of activin A in patients with acute myocardial infarction (AMI) undergoing successful primary percutaneous coronary intervention (PCI)...
  23. ncbi Prone position is essential for detection of pulmonary vein pseudostenosis by enhanced multidetector computed tomography in patients who undergo pulmonary vein isolation
    Hirosuke Yamaji
    Department of Cardiology, Sakakibara Heart Institute of Okayama, Okayama, Japan
    Circ J 72:1460-4. 2008
    ....
  24. ncbi Impact of chronic kidney disease on left main coronary artery disease and prognosis in Japanese patients
    Kazuhiro Dan
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Circ J 76:2266-72. 2012
    ..The aim of the present study was to investigate the prevalence of renal dysfunction and its impact on prognosis in patients with left main coronary artery disease (LMCAD) and stable angina pectoris...
  25. ncbi Hyaluronan receptors involved in cytokine induction in monocytes
    Hitoshi Yamawaki
    Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700 8558, Japan
    Glycobiology 19:83-92. 2009
    ..Hyaluronan receptors, CD44 and TLR4, play distinct roles in cytokine induction in hyaluronan-stimulated mononuclear cells...
  26. ncbi Circulating KCNH2 current-activating factor in patients with heart failure and ventricular tachyarrhythmia
    Hiroki Sugiyama
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    PLoS ONE 6:e19897. 2011
    ..Therefore, we investigated the existence of a circulating KCNH2 current-modifying factor in patients with HF...
  27. ncbi Impact of hypertriglyceridemia on endothelial dysfunction during statin ± ezetimibe therapy in patients with coronary heart disease
    Kei Yunoki
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Japan
    Am J Cardiol 108:333-9. 2011
    ..Ezetimibe add-on therapy improves endothelial function in these high-risk populations...
  28. ncbi Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice
    Toru Miyoshi
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
    FASEB J 20:1904-6. 2006
    ..In conclusion, our findings demonstrate that tumor-specific anti-angiogenic gene therapy utilizing RGD-alpha3(IV)NC1 under the hTERT promoter inhibited angiogenesis in tumors, resulting in an antitumor effect...
  29. ncbi Dynamic induction of ADAMTS1 gene in the early phase of acute myocardial infarction
    Keigo Nakamura
    Department of Medicine and Medical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama 700 8558, Japan
    J Biochem 136:439-46. 2004
    ..Our study demonstrated that the ADAMTS1 gene is a new early immediate gene expressed in the ischemic endothelium and myocardium...
  30. ncbi Fragmented QRS is associated with torsades de pointes in patients with acquired long QT syndrome
    Kayo Haraoka
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Heart Rhythm 7:1808-14. 2010
    ..Although various repolarization parameters have been evaluated in acquired LQTS, the existence of depolarization abnormality in association with torsades de pointes (TdP) has not been reported...
  31. ncbi Serum N-3 polyunsaturated fatty acid levels correlate with the extent of coronary plaques and calcifications in patients with acute myocardial infarction
    Masayuki Ueeda
    Division of Cardiovascular Medicine, Mitoyo General Hospital, Kagawa, Japan
    Circ J 72:1836-43. 2008
    ..The relationship between serum fatty acid levels and the extent of coronary plaques and calcification was examined in patients with acute myocardial infarction (AMI)...
  32. ncbi Safety and efficacy of a bolus injection of landiolol hydrochloride as a premedication for multidetector-row computed tomography coronary angiography
    Kazuhiro Osawa
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Circ J 77:146-52. 2012
    ....
  33. ncbi Circulating white blood cell count correlates with left ventricular indices independently of the extent of risk area for myocardial infarction after successful reperfusion
    Tadahisa Uesugi
    Department of Medicine and Medical Science, Okayama University Graduates School of Medicine and Dentistry, Okayama, Japan
    Acta Cardiol 59:533-9. 2004
    ....
  34. ncbi Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation
    Wakako Sumita Yoshikawa
    Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Circ J 77:741-8. 2013
    ..The aim of this study was to assess passive cardiomyocyte stiffness of hypertrophied hearts in the transverse direction and the influence of actin-myosin cross-bridge formation on the stiffness...