Kuniyuki Oka

Summary

Country: Japan

Publications

  1. doi request reprint A case report on a patient who presented with myelofibrosis, developed breast cancer with myeloid metaplasia, and finally showed immature NK-cell leukemia or AML without maturation with CD56 expression transformation in the pleura with extramedullary hema
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Res Pract 209:319-22. 2013
  2. doi request reprint G-CSF-producing malignant pleural mesothelioma: an autopsy case report with literature review
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Int J Surg Pathol 20:272-5. 2012
  3. doi request reprint Concurrent gastric MALT and Hodgkin lymphoma: a case report
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Int J Surg Pathol 20:201-4. 2012
  4. doi request reprint Epstein-Barr virus-associated lymphoproliferative disorder presenting with classical Hodgkin lymphoma and developing as peripheral T-cell lymphoma 9 years later: a case report of composite lymphoma
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Int 61:752-5. 2011
  5. ncbi request reprint Malignant adenomyoepithelioma of the breast with matrix production may be compatible with one variant form of matrix-producing carcinoma: a case report
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Pathol Res Pract 203:599-604. 2007
  6. ncbi request reprint Fulminant myocarditis demonstrating uncommon morphology--a report of two autopsy cases
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, 311 4198 Ibaraki, Japan
    Virchows Arch 446:259-64. 2005
  7. doi request reprint Epstein-Barr virus-associated proliferative disorder presenting as Hodgkin's lymphoma and developing as aggressive natural killer-cell leukemia 19 years later: a case report of composite lymphoma
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Res Pract 205:730-4. 2009
  8. ncbi request reprint Congenital cervical immature teratoma arising in the left lobe of the thyroid gland
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    APMIS 115:75-9. 2007
  9. ncbi request reprint Radiation therapy induces the p53(+)p21(-) expression in squamous cell carcinomas of the uterine cervix
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Gynecol Oncol 93:340-4. 2004
  10. ncbi request reprint Aggressive carcinoid tumors arising in the duodenum, ileum, and rectum with liver metastasis: a report of three cases
    Kuniyuki Oka
    Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Hepatogastroenterology 55:1660-3. 2008

Collaborators

Detail Information

Publications43

  1. doi request reprint A case report on a patient who presented with myelofibrosis, developed breast cancer with myeloid metaplasia, and finally showed immature NK-cell leukemia or AML without maturation with CD56 expression transformation in the pleura with extramedullary hema
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Res Pract 209:319-22. 2013
    ..Megakaryocytic and erythroblastic cells were also seen in the pleural effusion...
  2. doi request reprint G-CSF-producing malignant pleural mesothelioma: an autopsy case report with literature review
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Int J Surg Pathol 20:272-5. 2012
    ..They were positive for calretinin, D2-40, CK5/6, HBME-1, G-CSF, CK19, and E-cadherin. He was diagnosed with G-CSF-producing epithelioid malignant pleural mesothelioma...
  3. doi request reprint Concurrent gastric MALT and Hodgkin lymphoma: a case report
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Int J Surg Pathol 20:201-4. 2012
    ..Only CHL invaded into the regional lymph nodes. Two possibilities of transformation of MALT lymphoma into CHL and de novo CHL within MALT lymphoma are discussed...
  4. doi request reprint Epstein-Barr virus-associated lymphoproliferative disorder presenting with classical Hodgkin lymphoma and developing as peripheral T-cell lymphoma 9 years later: a case report of composite lymphoma
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Int 61:752-5. 2011
    ..This case is the first documented EBV-associated composite lymphoma composed of CHL and PTCL. The patient may show the possibility that both EBV infection and/or immunodeficiency induce the development of CHL and PTCL...
  5. ncbi request reprint Malignant adenomyoepithelioma of the breast with matrix production may be compatible with one variant form of matrix-producing carcinoma: a case report
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Pathol Res Pract 203:599-604. 2007
    ..Atypical myoepithelial cells expressed vimentin, S-100 protein, maspin, and MIC2. We conclude that malignant adenomyoepithelioma of the breast with matrix production might be compatible with a variant form of matrix-producing carcinoma...
  6. ncbi request reprint Fulminant myocarditis demonstrating uncommon morphology--a report of two autopsy cases
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, 311 4198 Ibaraki, Japan
    Virchows Arch 446:259-64. 2005
    ..Using reverse transcriptase-semi-nested polymerase chain reaction, picornaviral RNA was detected in the amplified products extracted from the paraffin-embedded myocardial sample of case 1 but not in case 2...
  7. doi request reprint Epstein-Barr virus-associated proliferative disorder presenting as Hodgkin's lymphoma and developing as aggressive natural killer-cell leukemia 19 years later: a case report of composite lymphoma
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Res Pract 205:730-4. 2009
    ..Neither a rearrangement band of the T-cell receptor gene nor that of the immunoglobulin heavy chain gene was detected. Chromosomal abnormalities were noted...
  8. ncbi request reprint Congenital cervical immature teratoma arising in the left lobe of the thyroid gland
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    APMIS 115:75-9. 2007
    ..Therefore, we concluded that the cervical tumor had arisen in the left lobe of the thyroid gland rather than from the soft tissue of the neck...
  9. ncbi request reprint Radiation therapy induces the p53(+)p21(-) expression in squamous cell carcinomas of the uterine cervix
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Gynecol Oncol 93:340-4. 2004
    ..Radiation therapy (RT) effect on p53 and p21 proteins after 27 Gy was analyzed...
  10. ncbi request reprint Aggressive carcinoid tumors arising in the duodenum, ileum, and rectum with liver metastasis: a report of three cases
    Kuniyuki Oka
    Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Hepatogastroenterology 55:1660-3. 2008
    ..Case 3 had a small submucosal tumor and showed a relatively high cell proliferation activity. Neoplastic cells expressed gastrin in Case 1, serotonin in Case 2, and did not express several peptides in Case 3...
  11. ncbi request reprint Pd-ECGF positivity correlates with better survival, while iNOS has no predictive value for cervical carcinomas treated with radiotherapy
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Int J Radiat Oncol Biol Phys 57:217-21. 2003
    ..Our purpose was to investigate the correlation between the expression of PD-ECGF or inducible NOS (iNOS) in cancer cells and prognosis...
  12. ncbi request reprint Nasal teratocarcinosarcoma - a case report
    Kuniyuki Oka
    Department of Pathology, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Pathol Res Pract 203:549-53. 2007
    ..Small amounts of mature chondroid tissue and neurofibrillary matrix were also present. Therefore, the tumor was diagnosed as nasal teratocarcinosarcoma...
  13. ncbi request reprint High growth fraction at 9 grays of radiotherapy is associated with a good prognosis for patients with cervical squamous cell carcinoma
    K Oka
    Division of Radiation Medicine, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Cancer 89:1526-31. 2000
    ..Cycling cells are positive for MIB-1 in their nucleus, and quiescent cells are negative for MIB-1. The MIB-1 labeling index represents the growth fraction of the cell population...
  14. doi request reprint Angioimmunoblastic T-cell lymphoma with autoimmune thrombocytopenia: a report of two cases
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki 311 4198, Japan
    Pathol Res Pract 206:270-5. 2010
    ..AILT with autoimmune thrombocytopenia (AIT) is very rare, and all the reported cases were Japanese ones...
  15. doi request reprint Coexistence of primary pulmonary Hodgkin lymphoma and gastric MALT lymphoma associated with Epstein-Barr virus infection: a case report
    Kuniyuki Oka
    Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Int 60:520-3. 2010
    ..The present case is a rare composite lymphoma arising from different extranodal organs, associated with EBV infection. Her medical history included gamma-knife therapy for clinical diagnosis with a suspicion of cerebral lymphoma...
  16. doi request reprint Bence-Jones protein-type myeloma with amyloid myopathy presenting as amyloidomas and extensive amyloid deposits in the muscularis propria: a rapidly fatal autopsy case
    Yoshiyasu Ikezawa
    Department of Pathology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Int J Surg Pathol 20:83-8. 2012
    ..Massive amyloid materials deposited diffusely in the propria muscularis of the gastrointestinal tract: the tongue to the rectum...
  17. ncbi request reprint Carbon beam therapy overcomes the radiation resistance of uterine cervical cancer originating from hypoxia
    Takashi Nakano
    Research Center Hospital of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Clin Cancer Res 12:2185-90. 2006
    ..However, no proof of this effect has been provided by clinical trials and related clinical research. Hence, we investigated the radiation biological aspects of high LET carbon beam therapy on cervical cancer...
  18. ncbi request reprint Primary jejunal malignant melanoma first noticed because of the presence of parotid lymph node metastasis
    Shigeruko Iijima
    Department of Dermatology, Mmito Saiseikai General Hospital, Mito, Japan
    J Am Acad Dermatol 49:319-23. 2003
    ..We discuss why the tumor in our case was considered primary, and we review similar cases of primary melanoma of the small intestine...
  19. ncbi request reprint Spindle and giant cell type undifferentiated carcinoma arising in the common bile duct: a case report
    Haruna Oikawa
    Department of Surgery, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki 311 4198, Japan
    Pathol Res Pract 203:179-84. 2007
    ..CD68-positive osteoclast-like giant cells were also observed. Therefore, the patient was diagnosed as having an undifferentiated carcinoma, spindle and giant cell type...
  20. ncbi request reprint Thyroid anaplastic carcinoma transformed from papillary carcinoma in extrathyroid area
    Shinji Togashi
    Department of Plastic and Reconstructive Surgery, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Auris Nasus Larynx 31:287-92. 2004
    ..This is rare case in which thyroid anaplastic carcinoma transformed from papillary carcinoma in an extrathyroid area...
  21. ncbi request reprint Primary cardiac B-cell lymphoma presented as heart tamponade and atrioventricular block: a case report
    Yoshiro Chiba
    Department of Cardiology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Acta Cytol 54:79-81. 2010
    ..Primay cardiac lymphoma is rare, and its diagnosis is not determined until autopsy...
  22. ncbi request reprint Osteosarcoma arising in the breast
    Norimasa Sando
    Surgery, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    APMIS 114:581-7. 2006
    ..Chemotherapy was not effective. The patient died of multiple pulmonary metastases 9 months after mastectomy...
  23. ncbi request reprint A case of ovarian mature cystic teratoma presenting as a pedunculated ileal tumor
    Yusuke Ohara
    Department of Surgery, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Pathol Res Pract 203:45-51. 2007
    ..The necrotic nodule showed abscess, granulation tissue, foreign body reaction, hairs, normal ileal epithelium, and the ovary with ovums...
  24. ncbi request reprint A common clonal origin of nodal marginal zone B-cell lymphoma and plasma cell myeloma demonstrating different immunophenotypes: a case report of composite lymphoma
    Hajime Saito
    Department of Hematology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Diagn Mol Pathol 13:75-80. 2004
    ..Sequence analysis of the IgH gene was a powerful tool for determination of clonal origin...
  25. doi request reprint Extensive endothelial replacement by tumor cells in the portal system: an autopsy case of intrahepatic cholangiocarcinoma
    Kyoko Minakawa
    Internal Medicine, Mito Saiseikai General Hospital, Ibaraki, Japan
    Pathol Int 60:591-4. 2010
    ..This form of extensive invasion of the tumor, termed intimal carcinoma spreading, caused complete obstruction of the portal system. To our knowledge there has been no report on this type of portal invasion of ICC...
  26. ncbi request reprint Coexisting true hermaphroditism and partial hydatidiform mole developing metastatic gestational trophoblastic tumors. A case report
    Hiroko Shiina
    Perinatology Center, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan
    Virchows Arch 441:514-8. 2002
    ..She responded well and is alive without any symptoms...
  27. ncbi request reprint A three-dimensional quantitative analysis of carpal deformity in rheumatoid wrists
    S Arimitsu
    Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2 2, Yamada oka, Suita, Osaka 565 0871, Japan
    J Bone Joint Surg Br 89:490-4. 2007
    ..In the midcarpal joint, the distal row was extended and congruity generally well preserved. These findings may facilitate more positive use of radiocarpal fusion alone for the deformed rheumatoid wrist...
  28. doi request reprint Pelioid-type well-differentiated hepatocellular carcinoma in a patient with a history of taking oral contraceptives: report of a case
    Naoya Ikeda
    Department of Surgery, Mito Saiseikai General Hospital, 3 3 10 Futabadai, Mito, Ibaraki, 311 4198, Japan
    Surg Today 41:1270-4. 2011
    ..The detection of stromal invasion into the portal area is necessary to distinguish well-differentiated HCC from benign hepatic tumors...
  29. ncbi request reprint Immunohistochemical study of cell cycle-associated proteins in adenocarcinoma of the uterine cervix treated with radiotherapy alone: P53 status has a strong impact on prognosis
    Yoshiyuki Suzuki
    Research Center Hospital of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Int J Radiat Oncol Biol Phys 60:231-6. 2004
    ..We analyzed the expression of the cell cycle-associated proteins p53, p27, p21/waf1/cip1, and cyclin D1 in cervical adenocarcinomas in correlation with the prognostic significance in tumors treated with RT alone...
  30. ncbi request reprint A case report of dystrophic localized amyloidosis that developed in the left thigh
    Atsushi Matsuba
    Orthopedics, Mito Saiseikai General Hospital, Mito, Ibaraki Jaopan
    Pathol Res Pract 201:603-8. 2005
    ..Therefore, it was suggested that this might be an amyloid derived from the hematoma, which has not been reported to date...
  31. ncbi request reprint Basal cell adenocarcinoma arising from the minor salivary gland in the soft palate: a case report
    Kenji Yamagata
    Division of Dentistry and Oral and Maxillofacial Surgery, Japan Department of Oral and Maxillofacial Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Pathol Res Pract 202:475-80. 2006
    ..The myxoid stroma was positive for alcian blue and colloidal iron. Apical membranes of the neoplastic cells were positive for MUC1 and CEA. The present case is the 14th documented case of oral BCAC (the fifth case of palatal BCAC)...
  32. ncbi request reprint Flow cytometric and Ki-67 immunohistochemical analysis of cell cycle distribution of cervical cancer during radiation therapy
    K H Higuchi
    Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba-shi, Japan
    Anticancer Res 21:2511-8. 2001
    ....
  33. doi request reprint Benign metastasizing leiomyoma of the lung: potential role of low-grade malignancy
    S Tatebe
    Thoracic and Cardiovascular Surgery, Mito Saiseikai General Hospital, Mito City, Japan
    Thorac Cardiovasc Surg 57:180-3. 2009
    ..The metastatic potential of BML is not completely understood, but previously reported cases of BML may include low-grade ESS, which may play a significant role in the metastasis of benign uterine tumors...
  34. ncbi request reprint Pelvic malignant mixed mesodermal tumor of uncertain origin: a case report
    Y Arai
    Department of Obstetrics and Gynecology, Mito Saiseikai General Hospital, Ibaraki, Japan
    Eur J Obstet Gynecol Reprod Biol 83:227-31. 1999
    ..We considered this case to be pelvic MMMT of uncertain origin, heterologous type...
  35. ncbi request reprint Unusual remnant thymic tissue in an adult mimicking malignant neoplasm: escape from age-related involution
    S Tatebe
    Department of Thoracic and Cardiovascular Surgery, Mito Saiseikai General Hospital, Mito City, Japan
    Thorac Cardiovasc Surg 54:138-40. 2006
    ..Although the cause of this unusual remnant thymic tissue remains unclear, it may have been related to autoimmune or endocrinological disease...
  36. ncbi request reprint Prognostic significance of c-erbB-2/HER2 expression in advanced uterine cervical carcinoma with para-aortic lymph node metastasis treated with radiation therapy
    Y Niibe
    Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    Int J Gynecol Cancer 13:849-55. 2003
    ..024). The present study suggests that c-erbB-2/HER2 expression of cervical tumors might be a predictive parameter of prognosis after radiation therapy for PALN of very advanced uterine cervical carcinoma patients...
  37. ncbi request reprint Benign clear cell tumor of the lung
    T Hashimoto
    Department of Internal Medicine, Mito Saiseikai General Hospital, Ibaraki, Japan
    Ultrastruct Pathol 25:479-83. 2001
    ..The neoplastic cells were surrounded by external lamina and cytoplasmic processes. The neoplastic clear cells showed morphologic features seen in pericytes, melanocytic cells, and neuroendocrine cells...
  38. ncbi request reprint Relative changes of MIB1 and PC10 labeling indexes in cell kinetics during radiotherapy for cervical squamous cell carcinoma
    K Oka
    Department of Pathology, Mito Saiseikai General Hospital, Ibaraki, Japan
    Acta Oncol 36:749-54. 1997
    ..The study of changes in cell cycle kinetics in human tumors during RT may have potential impact on the further development of RT...
  39. ncbi request reprint Platelet-derived endothelial cell growth factor as a prognostic factor for radiotherapy outcome in patients with adenocarcinoma of the uterine cervix
    Sang Young Ryu
    Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, 215 4 Gongneung dong, Nowon Ku, Seoul 139 706, South Korea
    Gynecol Oncol 89:414-9. 2003
    ..The aim of this study was to evaluate the platelet-derived endothelial cell growth factor (PD-ECGF) and VEGF expressions of tumor cells as prognostic factors for radiotherapy outcome in patients with adenocarcinoma of the uterine cervix...
  40. ncbi request reprint c-erbB-2 oncoprotein expression related to chemoradioresistance in esophageal squamous cell carcinoma
    Masayuki Akamatsu
    Department of Radiology, Juntendo University School of Medicine, Tokyo, Japan
    Int J Radiat Oncol Biol Phys 57:1323-7. 2003
    ....
  41. ncbi request reprint Correlation between survivin expression and locoregional control in cervical squamous cell carcinomas treated with radiation therapy
    Yoshiyuki Suzuki
    Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Gynecol Oncol 104:642-6. 2007
    ..However, the prognostic value of nuclear survivin expression is still equivocal. Here, we investigated the prognostic value of survivin expression in cervical cancer treated with radiation therapy...
  42. ncbi request reprint Pancreatic endocrine tumor with partial acinar cell differentiation
    Kyoko Minakawa
    Internal Medicine, Prefecture Medical Graduate School of Medical Sciences, Kyoto, Japan
    APMIS 114:720-5. 2006
    ..Neuroendocrine and zymogen granules were simultaneously observed in the cytoplasm of the same neoplastic cells at the ultrastructural level. The tumor may be considered an amphicrine tumor...
  43. pmc 5' terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart
    Nora M Chapman
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 6495, USA
    Virology 375:480-91. 2008
    ..This is the first report of these naturally-occurring defective enteroviral genomes in human myocarditis...