Akira Nishizono

Summary

Affiliation: Oita University
Country: Japan

Publications

  1. doi request reprint Evaluation of an improved rapid neutralizing antibody detection test (RAPINA) for qualitative and semiquantitative detection of rabies neutralizing antibody in humans and dogs
    Akira Nishizono
    Department of Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    Vaccine 30:3891-6. 2012
  2. ncbi request reprint Development and evaluation of a rapid neutralizing antibody test for rabies
    Seiji Shiota
    Department of Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita, Japan
    J Virol Methods 161:58-62. 2009
  3. doi request reprint Molecular epidemiology of human rabies viruses in Sri Lanka
    Takashi Matsumoto
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan
    Infect Genet Evol 18:160-7. 2013
  4. doi request reprint Molecular characterization of VP7 gene of human rotaviruses from Bangladesh
    Kamruddin Ahmed
    Division of Infectious Diseases, Department of Social and Environmental Medicine, Institute of Scientific Research, Oita University, Yufu, Oita, Japan
    Virus Genes 40:347-56. 2010
  5. ncbi request reprint Molecular epidemiology of rabies in Vietnam
    Junpei Yamagata
    Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, Oita University, Yufu, Oita, Japan
    Microbiol Immunol 51:833-40. 2007
  6. pmc Evaluation of a monoclonal antibody-based rapid immunochromatographic test for direct detection of rabies virus in the brain of humans and animals
    Kamruddin Ahmed
    Research Promotion Institute, Faculty of Medicine, Oita University, Yufu, Japan
    Am J Trop Med Hyg 86:736-40. 2012
  7. pmc Novel sylvatic rabies virus variant in endangered golden palm civet, Sri Lanka
    Takashi Matsumoto
    Oita University, Yufu, Japan
    Emerg Infect Dis 17:2346-9. 2011
  8. doi request reprint A simple and rapid immunochromatographic test kit for rabies diagnosis
    Akira Nishizono
    Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, Oita University, Yufu City, Oita, Japan
    Microbiol Immunol 52:243-9. 2008
  9. doi request reprint Whole-genome analysis of a human rabies virus from Sri Lanka
    Takashi Matsumoto
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan
    Arch Virol 156:659-69. 2011
  10. doi request reprint Evaluation of a new tumor necrosis factor-alpha-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen
    Kunimitsu Inoue
    Department of Microbiology, Faculty of Medicine, Oita University, Oita, Japan
    Helicobacter 14:135-43. 2009

Collaborators

Detail Information

Publications42

  1. doi request reprint Evaluation of an improved rapid neutralizing antibody detection test (RAPINA) for qualitative and semiquantitative detection of rabies neutralizing antibody in humans and dogs
    Akira Nishizono
    Department of Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    Vaccine 30:3891-6. 2012
    ..RAPINA can be used to monitor the success of preexposure prophylaxis in at-risk persons, vaccine coverage, and animal control. It can also be used in laboratories with modest facilities and where a large number of samples are screened...
  2. ncbi request reprint Development and evaluation of a rapid neutralizing antibody test for rabies
    Seiji Shiota
    Department of Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita, Japan
    J Virol Methods 161:58-62. 2009
    ..The RAPINA test is a simple, safe and rapid method, which can be a substitute for neutralizing tests that use live viruses, cultured cells and fluorescence microscopy. This test might be useful for screening a large number of sera...
  3. doi request reprint Molecular epidemiology of human rabies viruses in Sri Lanka
    Takashi Matsumoto
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan
    Infect Genet Evol 18:160-7. 2013
    ..This indicates that the movement of dogs, the main rabies-transmitting animal in Sri Lanka, is restricted in some areas but less limited in others. These data may help to formulate a more efficient rabies control program in Sri Lanka. ..
  4. doi request reprint Molecular characterization of VP7 gene of human rotaviruses from Bangladesh
    Kamruddin Ahmed
    Division of Infectious Diseases, Department of Social and Environmental Medicine, Institute of Scientific Research, Oita University, Yufu, Oita, Japan
    Virus Genes 40:347-56. 2010
    ..This study showed that the generation of diverse strains continued as evidenced by long G2, short G1 and G9 strains, and various combinations of G and P types...
  5. ncbi request reprint Molecular epidemiology of rabies in Vietnam
    Junpei Yamagata
    Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, Oita University, Yufu, Oita, Japan
    Microbiol Immunol 51:833-40. 2007
    ..Phylogenetically G genes of RVs from Vietnam and Thailand were clustered together. Our study suggests that Vietnamese and Thai RVs are closely related and might have originated from a common ancestor...
  6. pmc Evaluation of a monoclonal antibody-based rapid immunochromatographic test for direct detection of rabies virus in the brain of humans and animals
    Kamruddin Ahmed
    Research Promotion Institute, Faculty of Medicine, Oita University, Yufu, Japan
    Am J Trop Med Hyg 86:736-40. 2012
    ..The RICT is reliable, user friendly, rapid, robust, and can be used in laboratories with a modest infrastructure...
  7. pmc Novel sylvatic rabies virus variant in endangered golden palm civet, Sri Lanka
    Takashi Matsumoto
    Oita University, Yufu, Japan
    Emerg Infect Dis 17:2346-9. 2011
    ..We report a novel sylvatic rabies virus variant detected in a golden palm civet in Sri Lanka. Evolutionary analysis suggests the virus diverged from canine rabies viruses in Sri Lanka in ≈1933 (range 1886-1963)...
  8. doi request reprint A simple and rapid immunochromatographic test kit for rabies diagnosis
    Akira Nishizono
    Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, Oita University, Yufu City, Oita, Japan
    Microbiol Immunol 52:243-9. 2008
    ..This diagnostic test is suitable for rabies screening, particularly in areas with a high prevalence of rabies and where the fluorescent antibody test is not available...
  9. doi request reprint Whole-genome analysis of a human rabies virus from Sri Lanka
    Takashi Matsumoto
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan
    Arch Virol 156:659-69. 2011
    ..Whole-genome phylogenetic analysis showed that strain H-08-1320 formed an independent lineage and did not cluster with rabies viruses from other countries...
  10. doi request reprint Evaluation of a new tumor necrosis factor-alpha-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen
    Kunimitsu Inoue
    Department of Microbiology, Faculty of Medicine, Oita University, Oita, Japan
    Helicobacter 14:135-43. 2009
    ..We investigated the effects of vaccination with Tip alpha against H. pylori infection and analyzed the immune responses...
  11. doi request reprint Characterization of street rabies virus variants with an additional N-glycan at position 247 in the glycoprotein
    Kentaro Yamada
    Research Promotion Institute, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, 879 5593, Japan
    Arch Virol 159:207-16. 2014
    ..However, this attenuation was not attributable to the induction of strong immune responses. ..
  12. doi request reprint Molecular characterization of a human group C rotavirus detected first in Turkey
    Marcelo Takahiro Mitui
    Department of Microbiology, School of Medicine, Oita University, Yufu, Oita, Japan
    Virus Genes 39:157-64. 2009
    ....
  13. doi request reprint A pilot study on intradermal vaccination of Japanese rabies vaccine for pre-exposure immunization
    Seiji Shiota
    Department of Infectious Diseases Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    Vaccine 26:6441-4. 2008
    ..The intradermal PCEC-K regimen was found to be safe and effective in inducing adequate VNA levels with the use of a smaller quantity of vaccine and within a shorter period of time...
  14. doi request reprint Serial passage of a street rabies virus in mouse neuroblastoma cells resulted in attenuation: potential role of the additional N-glycosylation of a viral glycoprotein in the reduced pathogenicity of street rabies virus
    Kentaro Yamada
    Research Promotion Project, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita 879 5593, Japan
    Virus Res 165:34-45. 2012
    ..Taken together, we propose that the number of N-glycosylation sites in the G protein is one of the determinants of the pathogenicity of street rabies viruses...
  15. doi request reprint Co-dominance of G1 and emerging G3 rotaviruses in Hong Kong: a three-year surveillance in three major hospitals
    Marcelo Takahiro Mitui
    Department of Microbiology, School of Medicine, Oita University, Yufu, Oita, Japan
    J Clin Virol 50:325-33. 2011
    ..Sentinel surveillance is advised to monitor impact post-vaccine introduction and to document changes in genotype distribution...
  16. pmc Inaccurate identification of rotavirus genotype G9 as genotype G3 strains due to primer mismatch
    Marcelo Takahiro Mitui
    Department of Microbiology, School of Medicine, Oita University, Yufu, Oita, Japan
    Virol J 9:144. 2012
    ..Moreover, of 300 rotaviruses tested, 28.3% were untypable by set A primers whereas only 12.3% were untypable by set B primers. Our findings reinforce the need to periodically monitor the primers used for RVA genotyping...
  17. ncbi request reprint [Efficacy of intradermal regimen using Japanese rabies vaccine for pre-exposure prophylaxis]
    Seiji Shiota
    Department of Microbiology, Faculty of Medicine, Oita University
    Kansenshogaku Zasshi 84:9-13. 2010
    ..The intradermal PCEC-K regimen was found to be safe and effective in inducing adequate VNA using a smaller amount of vaccine within a shorter period...
  18. pmc Circulating rotaviral RNA in children with rotavirus antigenemia
    Kamruddin Ahmed
    Research Promotion Institute, Oita University, Yufu, Japan
    J Negat Results Biomed 12:5. 2013
    ..Such information may help in understanding rotavirus pathogenesis and eventually be useful for diagnosis, treatment and prevention...
  19. doi request reprint Highly efficient method of preparing human catalytic antibody light chains and their biological characteristics
    Emi Hifumi
    Research Center for Applied Medical Engineering, Faculty of Engineering, Oita University, 700 Dan noharu, Oita shi, Oita 870 1192, Japan
    FASEB J 26:1607-15. 2012
    ....
  20. doi request reprint Addition of a single N-glycan to street rabies virus glycoprotein enhances virus production
    Kentaro Yamada
    Research Promotion Institute, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita 879 5593, Japan
    J Gen Virol 94:270-5. 2013
    ....
  21. doi request reprint Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constructed human Fab library
    Tadamasa Shibuya
    Department of Infectious Diseases, Faculty of Medicine, Oita University, Oita 879 5593, Japan
    Microbiol Immunol 52:162-70. 2008
    ..The human monoclonal Fab product FabIF1A11 may have potential as a therapeutic or short-term prophylactic molecule for humans with influenza A H3N2 infection...
  22. ncbi request reprint Catalytic features and eradication ability of antibody light-chain UA15-L against Helicobacter pylori
    Emi Hifumi
    Research Center for Applied Medical Engineering, Oita University, Dan noharu 700, Oita shi, Oita 870 1192, Japan
    J Biol Chem 283:899-907. 2008
    ..pylori in a mouse stomach. This is the first example of a monoclonal catalytic antibody capable of functioning in vivo, and such an antibody may have a therapeutic utility in the future...
  23. ncbi request reprint Helicobacter pylori-associated oxidant monochloramine induces reactivation of Epstein-Barr virus (EBV) in gastric epithelial cells latently infected with EBV
    Junko Minoura-Etoh
    Microbiology, Department of Infectious Diseases, Faculty of Medicine, Oita University, Oita, Japan
    J Med Microbiol 55:905-11. 2006
    ..The results suggest that H. pylori-associated NH2Cl induces EBV lytic conversion in gastric epithelium latently infected with EBV...
  24. ncbi request reprint Construction of human Fab (gamma1/kappa) library and identification of human monoclonal Fab possessing neutralizing potency against Japanese encephalitis virus
    Mitsue Arakawa
    Department of Infectious Diseases, Faculty of Medicine, Oita University, Japan
    Microbiol Immunol 51:617-25. 2007
    ..8% homology to germline VH3-23, and used a Vkappa sequence homologous to the VkappaII subgroup showing 92.8% homology to germline A17...
  25. ncbi request reprint Construction of human Fab library and isolation of monoclonal Fabs with rabies virus-neutralizing ability
    Tadasuke Ando
    Department of Infectious Diseases, Faculty of Medicine, Oita University, Oita, Japan
    Microbiol Immunol 49:311-22. 2005
    ..The RV neutralizing ability of the Fab preparations described in the study were not directly correlated with their binding specificity for RV antigens detected by ELISA...
  26. ncbi request reprint Detection and molecular characterization of diarrhea causing viruses in single and mixed infections in children: A comparative study between Bangladesh and Turkey
    Marcelo Takahiro Mitui
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu Shi, Oita, Japan
    J Med Virol 86:1159-68. 2014
    ..Enteric viruses and mixed infections were more prevalent in Bangladesh than in Turkey. J. Med. Virol. 86:1159-1168, 2014. © 2013 Wiley Periodicals, Inc. ..
  27. doi request reprint Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis
    Marcelo Takahiro Mitui
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan
    Clin Infect Dis 54:964-7. 2012
    ..No further pathogens were detected in the cerebrospinal fluid of these patients...
  28. ncbi request reprint Efficacy of oncolytic reovirus against human gastric cancer with peritoneal metastasis in experimental animal model
    Koji Kawaguchi
    Department of Surgery I, Oita University Faculty of Medicine, Yufu, Oita 879 5593, Japan
    Int J Oncol 37:1433-8. 2010
    ..In conclusions, intraperitoneal administration of reovirus could be useful as a new modality against peritoneal metastasis in gastric cancer...
  29. pmc Commensal microbiota contributes to chronic endocarditis in TAX1BP1 deficient mice
    Satoko Nakano
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Oita, Japan Department of Ophthalmology, Faculty of Medicine, Oita University, Yufu, Oita, Japan
    PLoS ONE 8:e73205. 2013
    ..This experimental outcome raises a novel mechanistic linkage between endothelial inflammation caused by the ubiquitin remodeling immune regulators and fatal cardiac dysfunction. ..
  30. doi request reprint Isolation and characterization of novel human monoclonal antibodies possessing neutralizing ability against rabies virus
    Takashi Matsumoto
    Department of Microbiology, Faculty of Medicine, Oita University, Yufu City, Japan
    Microbiol Immunol 54:673-83. 2010
    ..Both human MAbs against rabies are expected to be utilized as a tool for future post-exposure prophylaxis...
  31. pmc Identification of the major antigenic protein of Helicobacter cinaedi and its immunogenicity in humans with H. cinaedi infections
    Hirofumi Iwashita
    Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860 8556, Japan
    Clin Vaccine Immunol 15:513-21. 2008
    ..cinaedi and is useful for immunological and serological testing for clinical diagnosis and for further epidemiological study of H. cinaedi infection in humans...
  32. ncbi request reprint Helicobacter pylori-infected animal models are extremely suitable for the investigation of gastric carcinogenesis
    Masaaki Kodama
    Department of Gastroenterology, Oita University, Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Oita Gun, Oita 879 55, Japan
    World J Gastroenterol 11:7063-71. 2005
    ....
  33. doi request reprint Rotavirus infections with multiple emerging genotypes in Sri Lanka
    Kamruddin Ahmed
    Division of Infectious Diseases, Department of Social and Environmental Medicine, Institute of Scientific Research, Oita University, Yufu 879 5593, Oita, Japan
    Arch Virol 155:71-5. 2010
    ..We conclude from the present study that multiple emerging genotypes were prevalent in Sri Lanka, and children in camps were at risk of developing diarrhea due to rotaviruses...
  34. ncbi request reprint Relationship between virus-neutralizing antibody levels and the number of rabies vaccinations: a prospective study of dogs in Japan
    Ippei Watanabe
    Department of Microbiology, Faculty of Medicine, Oita University, Oita, Japan
    Jpn J Infect Dis 66:17-21. 2013
    ..Thus, the current rabies vaccination schedule provides adequate protection, but the registration system and vaccination schedule needs to be improved to ensure that increased numbers of dogs are vaccinated against rabies...
  35. doi request reprint Efficient N-glycosylation at position 37, but not at position 146, in the street rabies virus glycoprotein reduces pathogenicity
    Kentaro Yamada
    School of Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita 879 5593, Japan Research Promotion Institute, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita 879 5593, Japan Electronic address
    Virus Res 179:169-76. 2014
    ..Thus, the results of the present study provide additional evidence that supports the relationship between G protein N-glycosylation and rabies virus evolution. ..
  36. ncbi request reprint Genetic analysis of rabies virus isolates in the Philippines
    Akira Nishizono
    Department of Microbiology, Oita Medical University, Japan
    Microbiol Immunol 46:413-7. 2002
    ..Several specific nucleotide and amino acid substitutions were observed among the Philippines isolates. Our results suggest that rabies viruses in the Philippines might have a characteristic evolution...
  37. ncbi request reprint [Rabies]
    Akira Nishizono
    Department of Microbiology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu Shi, Oita 879 5593, Japan
    Brain Nerve 61:135-44. 2009
    ..However, it is necessary to always remember that rabies is still a global burden as a representative of a re-emerging disease...
  38. ncbi request reprint [Rhabdoviruses]
    Akira Nishizono
    Department of Microbiology, Faculty of Medicine
    Uirusu 62:183-96. 2012
    ..In this review, we describe the sketch of the various virological features of the Rhabdoviridae, especially focusing on VSV and RABV...
  39. ncbi request reprint Reovirus inhibits the peritoneal dissemination of pancreatic cancer cells in an immunocompetent animal model
    Seitaro Hirano
    Department of Surgery I, Oita University Faculty of Medicine, Oita 879 5593, Japan
    Oncol Rep 21:1381-4. 2009
    ..There were no serious side effects observed in this study. These data suggested that intraperitoneal administration of reovirus might be an effective form of oncolytic viral therapy for peritoneal dissemination of pancreatic cancer...
  40. ncbi request reprint Seroprevalence of IgG specific for dengue virus among adults and children in Santo Domingo, Dominican Republic
    Tetsu Yamashiro
    Institute of Scientific Research, and Department of Infectious Diseases, Faculty of Medicine, Oita University, Oita, Japan
    Am J Trop Med Hyg 71:138-43. 2004
    ..Neutralization tests of adult samples indicate that DEN virus infections with different serotypes have occurred sequentially or simultaneously among the inhabitants of Santo Domingo...
  41. pmc Transfer of antigen-pulsed dendritic cells induces specific T-Cell proliferation and a therapeutic effect against long-term Helicobacter pylori infection in mice
    Satoshi Otsu
    Department of Infectious Diseases Microbiology, Faculty of Medicine, Oita University, Idaigaoka 1 1, Hasama machi, Oita 879 5593, Japan
    Infect Immun 74:984-93. 2006
    ..pylori antigens. The results suggest that Th1 cell-mediated immunity in combination with Th2 cell-mediated immunity plays a role in reducing colonizing bacterial numbers in mice with chronic H. pylori infections...
  42. ncbi request reprint Influence of temperature on growth of Legionella pneumophila biofilm determined by precise temperature gradient incubator
    Tadashi Konishi
    Faculty of Medicine, Oita University, 1 Idai gaoka, Yufu, Oita 879 5593, Japan
    J Biosci Bioeng 101:478-84. 2006
    ..is likely to happen...