Kazunari Murakami

Summary

Affiliation: Oita University
Country: Japan

Publications

  1. ncbi request reprint Multi-center randomized controlled study to establish the standard third-line regimen for Helicobacter pylori eradication in Japan
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yuhu, Oita, 879 5593, Japan
    J Gastroenterol 48:1128-35. 2013
  2. ncbi request reprint An evaluation of the performance of a novel stick-type kit for rapid detection of Helicobacter pylori antibodies in urine
    Kazunari Murakami
    Department of General Medicine, Faculty of Medicine, Oita University, Oita, Japan
    Clin Lab 57:481-7. 2011
  3. doi request reprint Serodiagnosis of Helicobacter hepaticus infection in patients with liver and gastrointestinal diseases: western blot analysis and ELISA using a highly specific monoclonal antibody for H. hepaticus antigen
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yuhu, Oita 879 5593, Japan
    J Gastroenterol 46:1120-6. 2011
  4. doi request reprint Genotyping of the cagA gene of Helicobacter pylori on immunohistochemistry with East Asian CagA-specific antibody
    Ryoko Kanada
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Pathol Int 58:218-25. 2008
  5. ncbi request reprint Effectiveness of minocycline-based triple therapy for eradication of Helicobacter pylori infection
    Kazunari Murakami
    Department of General Medicine, Faculty of Medicine, Oita University and Arita Gastrointestinal Disease Hospital, Oita, Japan
    J Gastroenterol Hepatol 21:262-7. 2006
  6. ncbi request reprint Impact of Helicobacter pylori CagA diversity on gastric mucosal damage: an immunohistochemical study of East-Asian-type CagA
    Takashi Abe
    Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan
    J Gastroenterol Hepatol 26:688-93. 2011
  7. ncbi request reprint Histological characteristics of gastric mucosa prior to Helicobacter pylori eradication may predict gastric cancer
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University, Hasama machi, Oita, 879 5593, Japan
    Scand J Gastroenterol 48:1249-56. 2013
  8. ncbi request reprint Comparison of amoxicillin-metronidazole plus famotidine or lansoprazole for amoxicillin-clarithromycin-proton pump inhibitor treatment failures for Helicobacter pylori infection
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasama, Oita 879 5593, Japan
    Helicobacter 11:436-40. 2006
  9. doi request reprint Ten-year prospective follow-up of histological changes at five points on the gastric mucosa as recommended by the updated Sydney system after Helicobacter pylori eradication
    Masaaki Kodama
    Department of Gastroenterology, Oita University, Hasama machi, Oita 879 5593, Japan
    J Gastroenterol 47:394-403. 2012
  10. pmc Prevalence of two homologous genes encoding glycosyltransferases of Helicobacter pylori in the United States and Japan
    Miyuki Matsuda
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Gastroenterol Hepatol 26:1451-6. 2011

Detail Information

Publications65

  1. ncbi request reprint Multi-center randomized controlled study to establish the standard third-line regimen for Helicobacter pylori eradication in Japan
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yuhu, Oita, 879 5593, Japan
    J Gastroenterol 48:1128-35. 2013
    ..The present study sought to establish a standard third-line eradication regimen for Helicobacter pylori in Japan...
  2. ncbi request reprint An evaluation of the performance of a novel stick-type kit for rapid detection of Helicobacter pylori antibodies in urine
    Kazunari Murakami
    Department of General Medicine, Faculty of Medicine, Oita University, Oita, Japan
    Clin Lab 57:481-7. 2011
    ..pylori infection. The aim of this study was to evaluate the performance and correlation of this kit with the original kit and the ELISA kit...
  3. doi request reprint Serodiagnosis of Helicobacter hepaticus infection in patients with liver and gastrointestinal diseases: western blot analysis and ELISA using a highly specific monoclonal antibody for H. hepaticus antigen
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yuhu, Oita 879 5593, Japan
    J Gastroenterol 46:1120-6. 2011
    ..Helicobacter hepaticus infection might be associated with liver and biliary tract diseases. To investigate its pathogenic role, the properties of anti-H. hepaticus serum antibody in patients with liver and diseases were elucidated...
  4. doi request reprint Genotyping of the cagA gene of Helicobacter pylori on immunohistochemistry with East Asian CagA-specific antibody
    Ryoko Kanada
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Pathol Int 58:218-25. 2008
    ..2%) and specific (specificity 72.7%), suggesting that immunohistochemical diagnosis of the cagA genotype is useful for diagnosis of the cagA genotype...
  5. ncbi request reprint Effectiveness of minocycline-based triple therapy for eradication of Helicobacter pylori infection
    Kazunari Murakami
    Department of General Medicine, Faculty of Medicine, Oita University and Arita Gastrointestinal Disease Hospital, Oita, Japan
    J Gastroenterol Hepatol 21:262-7. 2006
    ..The purpose of the present paper was to measure the in vitro antibacterial activity of minocycline against H. pylori, and study the effectiveness of minocycline-based first- and second-line eradication therapies...
  6. ncbi request reprint Impact of Helicobacter pylori CagA diversity on gastric mucosal damage: an immunohistochemical study of East-Asian-type CagA
    Takashi Abe
    Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan
    J Gastroenterol Hepatol 26:688-93. 2011
    ..In this study, the correlations between Helicobacter pylori CagA protein diversity and gastric mucosal condition was investigated using immunohistochemical staining with α-EAS Ab in Japan...
  7. ncbi request reprint Histological characteristics of gastric mucosa prior to Helicobacter pylori eradication may predict gastric cancer
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University, Hasama machi, Oita, 879 5593, Japan
    Scand J Gastroenterol 48:1249-56. 2013
    ..Although Helicobacter pylori (H. pylori) eradication has been shown to inhibit gastric cancer, it does not completely suppress it. Therefore, risk factors of gastric cancer development following H. pylori eradication were examined...
  8. ncbi request reprint Comparison of amoxicillin-metronidazole plus famotidine or lansoprazole for amoxicillin-clarithromycin-proton pump inhibitor treatment failures for Helicobacter pylori infection
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka Hasama, Oita 879 5593, Japan
    Helicobacter 11:436-40. 2006
    ..The authors assessed the efficacy and safety of second-line eradication using the H2-receptor antagonist famotidine as a substitute for proton pump inhibitor...
  9. doi request reprint Ten-year prospective follow-up of histological changes at five points on the gastric mucosa as recommended by the updated Sydney system after Helicobacter pylori eradication
    Masaaki Kodama
    Department of Gastroenterology, Oita University, Hasama machi, Oita 879 5593, Japan
    J Gastroenterol 47:394-403. 2012
    ..pylori eradication at five points of the stomach as recommended by the updated Sydney system to clarify the relationship between H. pylori eradication and gastric cancer prevention...
  10. pmc Prevalence of two homologous genes encoding glycosyltransferases of Helicobacter pylori in the United States and Japan
    Miyuki Matsuda
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Gastroenterol Hepatol 26:1451-6. 2011
    ..We examined the prevalence of jhp0562, β-(1,3)galT, and cagA in the United States (US) and Japanese populations...
  11. doi request reprint Comparison of the efficacy of irsogladine maleate and famotidine for the healing of gastric ulcers after Helicobacter pylori eradication therapy: a randomized, controlled, prospective study
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, Japan
    Scand J Gastroenterol 46:287-92. 2011
    ..pylori eradication therapy. We therefore compared the efficacy of irsogladine with famotidine as appropriate treatments for ulcers after eradication therapy...
  12. doi request reprint Evaluation of Helicobacter pylori status and endoscopic findings among new outpatients with dyspepsia in Japan
    Seiji Shiota
    Department of General Medicine, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama machi, Yufu, Oita, 879 5593, Japan
    J Gastroenterol 44:930-4. 2009
    ..pylori-positive and-negative, respectively. To establish Japanese guidelines for dyspepsia, we evaluated H. pylori status and endoscopic findings among outpatients with dyspepsia...
  13. doi request reprint Helicobacter pylori eradication improves gastric atrophy and intestinal metaplasia in long-term observation
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan
    Digestion 85:126-30. 2012
    ..To clarify the mechanism by which H. pylori eradication prevents gastric cancer, we monitored atrophy and IM improvement in gastric mucosa over a long period after H. pylori eradication...
  14. pmc Association between Helicobacter pylori cagA-related genes and clinical outcomes in Colombia and Japan
    Masahide Watada
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Idaigaoka, Hasama machi, Yufu City, Japan
    BMC Gastroenterol 11:141. 2011
    ..Therefore, we aimed to find novel candidate virulence genes that correlate with cagA and examined the association of these genes with clinical outcomes in Colombian and Japanese populations...
  15. pmc Association between Helicobacter pylori virulence factors and gastroduodenal diseases in Okinawa, Japan
    Osamu Matsunari
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu City, Oita, Japan
    J Clin Microbiol 50:876-83. 2012
    ..Overall, low prevalence of gastric cancer in Okinawa may result from the high prevalence of non-East-Asian-type cagA strains. The origin of Western-type cagA strains in Okinawa may be different from those of Western countries...
  16. pmc Effect of sucralfate on antibiotic therapy for Helicobacter pylori infection in mice
    Koichiro Watanabe
    Department of Infectious Diseases, Faculty of Medicine, Oita University, Oita, Japan
    Antimicrob Agents Chemother 48:4582-8. 2004
    ..Sucralfate delays gastric clearance of CAM and physically captures H. pylori through the creation of an adherent mucus, which leads to bacterial clearance...
  17. doi request reprint Evaluation of three different proton pump inhibitors with amoxicillin and metronidazole in retreatment for Helicobacter pylori infection
    Kazunari Murakami
    Faculty of Medicine, Department of Gastroenterology, Oita University, Oita, Japan
    J Clin Gastroenterol 42:139-42. 2008
    ....
  18. pmc Association of helicobacter pylori dupA with the failure of primary eradication
    Seiji Shiota
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    J Clin Gastroenterol 46:297-301. 2012
    ..To determine whether the presence of dupA Helicobacter pylori (H. pylori) influences the cure rate of primary eradication therapy...
  19. doi request reprint Evaluation of rapid urine test for the detection of Helicobacter pylori infection in the Vietnamese population
    Lam Tung Nguyen
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu City, Oita 879 5593, Japan
    Dig Dis Sci 55:89-93. 2010
    ..This study attempted to assess the value of the RAPIRUN test for the diagnosis of Helicobacter pylori infection in the Vietnamese population...
  20. ncbi request reprint Helicobacter pylori-infected animal models are extremely suitable for the investigation of gastric carcinogenesis
    Masaaki Kodama
    Department of Gastroenterology, Oita University, Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Oita Gun, Oita 879 55, Japan
    World J Gastroenterol 11:7063-71. 2005
    ....
  21. ncbi request reprint Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population: a randomized, double-blind, placebo-controlled trial
    Akira Terano
    Department of Gastroenterology, Dokkyo University School of Medicine, Tochigi, Japan
    J Gastroenterol 42:690-3. 2007
    ..We examined the efficacy of rebamipide in gastric ulcer healing following 1 week of eradication therapy in a randomized, double-blind, placebo-controlled trial...
  22. doi request reprint Development of corpus atrophic gastritis may be associated with Helicobacter pylori-related idiopathic thrombocytopenic purpura
    Ryugo Sato
    Department of Gastroenterology and General Medicine, Oita University, Idaigaoka, Hasama machi, Yufu, Japan
    J Gastroenterol 46:991-7. 2011
    ..To clarify the pathogenesis of H. pylori-induced ITP and the factors predicting the platelet response to H. pylori eradication therapy, we evaluated the markers of atrophic gastritis in ITP patients...
  23. ncbi request reprint Maintenance therapy with H2-receptor antagonist until assessment of Helicobacter pylori eradication can reduce recurrence of peptic ulcer after successful eradication of the organism: prospective randomized controlled trial
    Kazunari Murakami
    Second Department of Internal Medicine, Oita University, 1 1 Hasama, Oita, Japan
    J Gastroenterol Hepatol 21:1048-53. 2006
    ..This study examined the possible relationship between peptic ulcer recurrence and the presence or absence of maintenance therapy with an H(2)-receptor antagonist performed until evaluation of Helicobacter pylori eradication...
  24. ncbi request reprint Influence of bile reflux and Helicobacter pylori infection on gastritis in the remnant gastric mucosa after distal gastrectomy
    Hisanori Abe
    Arita Gastro Intestinal Hospital, 1 2 6 Maki, Oita, 870 0924, Japan
    J Gastroenterol 40:563-9. 2005
    ....
  25. ncbi request reprint Expression of mutant type-p53 products in H pylori-associated chronic gastritis
    Masaaki Kodama
    Department of Gastroenterology, Oita University, Hasama machi, Oita, 879 5593, Japan
    World J Gastroenterol 13:1541-6. 2007
    ..To investigate the mutation of p53 immunohistochemically in non-tumorous gastric mucosa with H pylori infection before and after H pylori eradication therapy...
  26. ncbi request reprint A diagnosis of depression should be considered in patients with multiple physical symptoms in primary care clinics
    Kyoko Yamamoto
    Department of General Medicine, Oita University, Faculty of Medicine, Yufu, Oita, Japan
    Tohoku J Exp Med 229:279-85. 2013
    ..A diagnosis of depression should be considered in patients who report multiple physical symptoms...
  27. pmc Aspirin-induced small bowel injuries and the preventive effect of rebamipide
    Kazuhiro Mizukami
    Department of General Medicine and Gastroenterology, Faculty of Medicine, Oita University, Yufu, Oita 879 5593, Japan
    World J Gastroenterol 17:5117-22. 2011
    ..To evaluate the influence of taking low-dose aspirin for 4 wk on small intestinal complications and to examine the preventive effect of rebamipide...
  28. pmc Evaluation of the anti-East Asian CagA-specific antibody for CagA phenotyping
    Lam Tung Nguyen
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Yufu City, Oita, Japan
    Clin Vaccine Immunol 16:1687-92. 2009
    ..7%, 97.9%, and 97.1%, respectively. Moreover, anti-EAS Ab was not cross-reactive with noninfected gastric mucosa. In conclusion, immunohistochemistry with anti-EAS Ab appears to be a good method for determination of CagA phenotype...
  29. doi request reprint A novel diagnostic monoclonal antibody specific for Helicobacter pylori CagA of East Asian type
    Aiko Yasuda
    Institute of Scientific Research, Faculty of Medicine, Oita University, Oita, Japan
    APMIS 117:893-9. 2009
    ..We also analyzed the localization of the CagA protein in H. pylori-infected gastric mucosa with fluorescence immunohistochemistry, and found that CagA protein expression was up-regulated by adhesion to epithelial cells...
  30. doi request reprint Helicobacter pylori and NSAID-induced gastric ulcer in a Japanese population
    Kazunari Murakami
    Department of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasama, Oita, 879 5593, Japan
    J Gastroenterol 44:40-3. 2009
    ..In Japan, national health insurance does not cover procedures that prevent or lower the risk for NSAID-induced ulcer. When administering NSAID to patients with risk factors, it is desirable to administer antiulcer agents...
  31. ncbi request reprint Helicobacter pylori eradication and associated changes in the gastric mucosa
    Kazunari Murakami
    Department of Gastroenterology, Oita University, Faculty of Medicine, 1 1 Hasama, Oita 879 5593, Japan
    Expert Rev Anti Infect Ther 3:757-64. 2005
    ..pylori eradication is also required to explore strategies for the prevention of gastric cancer with H. pylori eradication...
  32. ncbi request reprint Effect of Helicobacter pylori eradication on platelet recovery in patients with chronic idiopathic thrombocytopenic purpura
    Ryugo Sato
    Second Department of Internal Medicine, Faculty of Medicine, Oita University, Oita, Japan
    Arch Intern Med 164:1904-7. 2004
    ..We determined the prevalence of H pylori infection in Japanese patients with chronic ITP and the effect of its eradication on platelet count...
  33. ncbi request reprint Eradication of Helicobacter pylori reduced the immunohistochemical detection of p53 and MDM2 in gastric mucosa
    Masaaki Kodama
    Department of General Medicine, Faculty of Medicine, Oita University, Hasama machi, Oita 879 5593, Japan
    J Gastroenterol Hepatol 20:941-6. 2005
    ..To clarify the role of H. pylori in carcinogenesis, the expression of tumor suppressor p53 and its regulator multiple double minute 2 (MDM2) in gastric mucosa were examined before and after H. pylori eradication...
  34. ncbi request reprint [Guidelines for the management of Helicobacter pylori--Maastricht III-2005 and Japanese guidelines]
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University
    Nihon Rinsho 66:804-10. 2008
    ..Japanese guideline in 2003 does not mention the effect of eradication for prevention of gastric cancer. The H. pylori eradication and new strategy should be desirable for global strategy of gastric cancer prevention...
  35. doi request reprint Evaluation of esophageal function in patients with gastroesophageal reflux disease using transnasal endoscopy
    Shigeaki Yasaka
    Department of Gastroenterology, Oita University Faculty of Medicine, Yufu, Oita 879 5593, Japan
    J Gastroenterol Hepatol 24:1677-82. 2009
    ..To investigate the utility of a new method of carrying out esophageal manometry using a narrow gauge manometry catheter via a transnasal endoscope...
  36. ncbi request reprint [Sclerosing cholangitis with autoimmune pancreatitis which resembles cholangiocarcinoma]
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu
    Nihon Naika Gakkai Zasshi 96:2525-8. 2007
  37. ncbi request reprint Helicobacter pylori and gastric carcinoma--from the view point of animal model
    Toshio Fujioka
    Department of General Medicine, Oita Medical University, Oita, Japan
    Keio J Med 51:69-73. 2002
    ..These important results provide a starting point for further studies to clarify the mechanism of gastric carcinogenesis as a result of H. pylori infection and assist the planning of eradication therapy to prevent gastric carcinoma...
  38. pmc Genomic profiling of submucosal-invasive gastric cancer by array-based comparative genomic hybridization
    Akiko Kuroda
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan
    PLoS ONE 6:e22313. 2011
    ....
  39. pmc The relationship between Helicobacter pylori infection and Alzheimer's disease in Japan
    Seiji Shiota
    Department of General Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu, Oita 879 5593, Japan
    J Neurol 258:1460-3. 2011
    ..83, respectively). The prevalence of H. pylori infection did not differ between AD patients and controls among Japanese subjects. The high prevalence of H. pylori in controls may contribute to the discrepancy with previous reports...
  40. doi request reprint Helicobacter pylori virulence and the diversity of gastric cancer in Asia
    Lam Tung Nguyen
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita 879 5593, Japan
    J Med Microbiol 57:1445-53. 2008
    ..The possible link between the geographical distribution of cagPAI and cagA variations and gastric cancer diversity in Asia is also discussed...
  41. ncbi request reprint [The effect of Helicobacter pylori eradication on chronic gastritis]
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University
    Nihon Rinsho 71:1442-8. 2013
    ..Therefore, improvement or elimination of chronic gastritis with H. pylori eradication might have possibility of gastric cancer inhibition...
  42. pmc Prevalence of gastroduodenal ulcers/erosions in patients taking low-dose aspirin with either 15 mg/day of lansoprazole or 40 mg/day of famotidine: the OITA-GF study 2
    Akira Tamura
    Internal Medicine 2, Oita University, Yufu, Japan
    BMC Res Notes 6:116. 2013
    ..We conducted a cross-sectional study to compare the prevalence of gastroduodenal ulcers or erosions in patients taking LDA with either 40 mg/day of famotidine or 15 mg/day of lansoprazole for at least three months...
  43. pmc Population-based strategies for Helicobacter pylori-associated disease management: a Japanese perspective
    Seiji Shiota
    Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama machi, Yufu City, Oita 879 5593, Japan
    Expert Rev Gastroenterol Hepatol 4:149-56. 2010
    ..Overall, the most important and dramatic revision is that all infected people are recommended to receive eradication therapy irrespective of the clinical outcomes in the Japanese population...
  44. ncbi request reprint Immunohistochemical diagnosis of the cagA-gene genotype of Helicobacter pylori with anti-East Asian CagA-specific antibody
    Tomohisa Uchida
    Department of Molecular Pathology, Oita University, Yufu City, Oita 879 5593, Japan
    Cancer Sci 98:521-8. 2007
    ....
  45. ncbi request reprint Latest insights into the effects of Helicobacter pylori infection on gastric carcinogenesis
    Kazunari Murakami
    Department of Gastroenterology, Oita University Faculty of Medicine, 1 1 Idaigaoka, Hasama, Oita 879 5593, Japan
    World J Gastroenterol 12:2713-20. 2006
    ..Further progress in research into H pylori eradication as a viable prophylaxis of gastric cancer, as well as into the mechanisms of gastric carcinogenesis, is to be eagerly awaited for the current year and beyond...
  46. ncbi request reprint Guidelines for the management of Helicobacter pylori infection in Japan: current status and future prospects
    Toshio Fujioka
    Department of Gastroenterology and Division of Digestive Endoscopy, Oita University Faculty of Medicine, 1 1 Idaigaoka, Yufu, 879 5593, Japan
    J Gastroenterol 42:3-6. 2007
    ..Finally, areas requiring further clinical research and endeavors, including establishment of second-line eradication therapy, were also proposed in the 2003 Guidelines to point the way for the future...
  47. doi request reprint Genomic profiling of gastric carcinoma in situ and adenomas by array-based comparative genomic hybridization
    Masahiro Uchida
    Department of Molecular Pathology, Oita University, Oita, Japan
    J Pathol 221:96-105. 2010
    ..Since HGA is believed to have a higher risk of progression to invasive carcinoma than LGA, these data suggest that 8q gain is important for the malignant transformation of gastric adenoma...
  48. ncbi request reprint Is the recurrence of Helicobacter pylori infection after eradication therapy resultant from recrudescence or reinfection, in Japan
    Tadayoshi Okimoto
    Second Department of Internal Medicine, and Department of General Medicine, Oita Medical University, Oita, Japan
    Helicobacter 8:186-91. 2003
    ..In the present study, we attempted to differentiate between reinfection and recrudescence of H. pylori strains between 6 months and 6 years after successful eradication in Japan, a country with a high prevalence of H. pylori infection...
  49. doi request reprint Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition
    Masahiro Asaka
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Helicobacter 15:1-20. 2010
    ..pylori and gastric cancer has been demonstrated more clearly. Accordingly, the committee of the Japanese Society for Helicobacter Research has revised the guidelines for diagnosis and treatment of H. pylori infection in Japan...
  50. ncbi request reprint Intraperitoneal immunization led to T cell hyporesponsiveness to Helicobacter pylori infection in mice
    Koichiro Watanabe
    Department of Microbiology, Oita Medical University, Oita, Japan
    Microbiol Immunol 46:441-7. 2002
    ..pylori-associated gastritis and induced T cell hyporesponsiveness to H. pylori infection, which might be mediated by the early induction of CTLA-4 following challenge...
  51. pmc Influence of proton pump inhibitor treatment on Helicobacter pylori stool antigen test
    Masaaki Kodama
    Department of Gastroenterology, Faculty of Medicine, Oita University, Yufu City, Oita 879 5593, Japan
    World J Gastroenterol 18:44-8. 2012
    ..To investigate the effects of proton pump inhibitor (PPI) treatment on stool antigen test using the TestMate pylori enzyme immunoassay...
  52. doi request reprint Evaluation of selective cyclooxygenase-2 inhibitor-induced small bowel injury: randomized cross-over study compared with loxoprofen in healthy subjects
    Kazuhiro Mizukami
    Department of Gastroenterology, Oita University, Yufu, Oita 879 5593, Japan
    Dig Endosc 25:288-94. 2013
    ..The present study was conducted to compare the extents of small bowel mucosal injury induced by celecoxib and loxoprofen (the most frequently used non-steroidal anti-inflammatory drugs in Japan)...
  53. ncbi request reprint Animal models for the study of Helicobacter-induced gastric carcinoma
    Masaaki Kodama
    Department of General Medicine, Oita University, Hasama machi, Oita 879 5593, Japan
    J Infect Chemother 10:316-25. 2004
    ..These important results provide a starting point for further studies to clarify the mechanism of gastric carcinogenesis as a result of H. pylori infection and assist in the planning of eradication therapy to prevent gastric carcinoma...
  54. ncbi request reprint Pancreatic injury successfully treated with endoscopic stenting for major pancreatic duct disruption
    Takashi Abe
    Department of General Medicine and Gastroenterology, Faculty of Medicine, Oita University, Yufu, Japan
    Intern Med 48:1889-92. 2009
    ..CT on the 9th hospital day showed acute pancreatic fluid collections, but these had disappeared at the 3 month follow-up CT. The patient has remained asymptomatic at follow-up for 3 years...
  55. ncbi request reprint [Acquisition of the drug resistance and Helicobacter pylori gene mutation]
    Tadayoshi Okimoto
    Department of Gastroenterology, Faculty of Medicine, Oita University
    Nihon Rinsho 67:2372-7. 2009
    ..The resistant rates of each antibiotics may increase in future, so we need to observe those changes...
  56. ncbi request reprint [Second-line eradication therapy for H. pylori infection--PPI+AMPC+MNZ triple therapy]
    Tadayoshi Okimoto
    Department of Gastroenterology, Faculty of Medicine, Oita University
    Nihon Rinsho 63:435-7. 2005
  57. pmc Efficacy of rebamipide for low-dose aspirin-related gastrointestinal symptoms
    Kazuhiro Mizukami
    Departments of Gastroenterology, Faculty of Medicine, Oita University, 1 1 Idaigaoka, Hasamamachi, Yufu, Oita 879 5593, Japan
    J Clin Biochem Nutr 51:216-20. 2012
    ..Rebamipide is a candidate drug for combination therapy with proton pump inhibitors to prevent low-dose aspirin-induced gastrointestinal symptoms...
  58. pmc Helicobacter pylori infection and gastroduodenal diseases in Vietnam: a cross-sectional, hospital-based study
    Tung L Nguyen
    Department of Molecular Pathology, Oita University, Yufu City, Japan
    BMC Gastroenterol 10:114. 2010
    ..The virulence of Vietnamese H. pylori has also not been investigated in detail...
  59. ncbi request reprint Enterocromaffin-like cell tumor induced by Helicobacter pylori infection in Mongolian gerbils
    Jiro Kagawa
    Department of General Medicine, Oita Medical University, Hasama machi, Oita, Japan
    Helicobacter 7:390-7. 2002
    ..Since Helicobacter pylori infection causes hypergastrinemia, it is held that H. pylori infection produces gastric carcinoids. We followed the histological changes of H. pylori-infected stomachs of Mongolian gerbils for a long time...
  60. ncbi request reprint [Characteristics of gastric cancer occurring after Helicobacter pylori eradication]
    Ryugo Sato
    Department of Gastroenterology, Faculty of Medicine, Oita University
    Nihon Rinsho 63:520-5. 2005
  61. ncbi request reprint [A case of simple ulcer with ulcerative colitis]
    Masami Ono
    Second Department of Internal Medicine, Faculty of Medicine, Oita University
    Nihon Shokakibyo Gakkai Zasshi 102:894-9. 2005
  62. ncbi request reprint Recurrent peptic ulcers in patients following successful Helicobacter pylori eradication: a multicenter study of 4940 patients
    Hiroto Miwa
    Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan
    Helicobacter 9:9-16. 2004
    ..The aim of this study is to describe the recurrence rate and specific features of peptic ulcers after cure of H. pylori infection...
  63. pmc Analysis of virulence factors of Helicobacter pylori isolated from a Vietnamese population
    Tomohisa Uchida
    Department of Molecular Pathology, Oita University Faculty of Medicine, Yufu, Japan
    BMC Microbiol 9:175. 2009
    ..The aim of this study was to investigate several genetic factors regarded as virulence or molecular epidemiologic markers in H. pylori isolates from Vietnamese subjects...
  64. ncbi request reprint Gastritis associated with Epstein-Barr virus infection
    Akari Hisamatsu
    Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Beppu
    Intern Med 49:2101-5. 2010
    ..Her symptoms spontaneously resolved, and follow-up endoscopy revealed improvement and no atypical lymphocytes. To prevent misdiagnosis and unnecessary treatment, the possibility of EBV-associated gastritis should be considered...
  65. ncbi request reprint Duodenal gangliocytic paraganglioma treated with endoscopic hemostasis and resection
    Takayuki Nagai
    Department of Gastroenterology, Oita Kouseiren Tsurumi Hospital, Beppu, Japan
    J Gastroenterol 39:277-83. 2004
    ..In Japan, no previous studies have reported using endoscopic hemostasis, to our knowledge. Our patient is the fourth in Japan to be treated by endoscopic resection. We report on our patient, with a review of the literature...