T Daa

Summary

Affiliation: Oita University
Country: Japan

Publications

  1. doi request reprint Alteration of SMAD4 does not participate in tumorigenesis of adenoid cystic carcinoma of the salivary gland
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita Universeity, Oita 879 5593, Japan
    Mol Med Report 2:13-5. 2009
  2. doi request reprint Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary gland
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    APMIS 116:21-6. 2008
  3. ncbi request reprint Mutations in components of the Wnt signaling pathway in adenoid cystic carcinoma
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Mod Pathol 17:1475-82. 2004
  4. ncbi request reprint Expression of beta-catenin, E-cadherin and cyclin D1 in adenoid cystic carcinoma of the salivary gland
    T Daa
    Dept of Pathology, Oita Medical University, Oita, Japan
    J Exp Clin Cancer Res 24:83-7. 2005
  5. ncbi request reprint Epithelial-myoepithelial carcinoma harboring p53 mutation
    T Daa
    1st Department of Pathology, Oita Medical University, Japan
    APMIS 109:316-20. 2001
  6. ncbi request reprint Expression of vascular endothelial growth factor and its receptors in the developing rat lung
    A Marszalek
    First Department of Pathology, Oita Medical University, Hasama machi, Oita Gun, Oita, 879 5593 Japan
    Jpn J Physiol 51:313-8. 2001
  7. ncbi request reprint Cytoplasmic biotin-like activity interferes with immunohistochemical analysis of thyroid lesions: a comparison of antigen retrieval methods
    K Kashima
    Department of Pathology, Oita Medical University, Japan
    Mod Pathol 10:515-9. 1997
  8. ncbi request reprint The Wnt-signaling pathway is not implicated in tumorigenesis of Merkel cell carcinoma
    Shuang Liu
    First Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    J Cutan Pathol 34:22-6. 2007
  9. ncbi request reprint Quantitative immunohistochemical analysis of the expression of CD31 during lung development in the rat
    A Marszalek
    First Department of Pathology, Oita Medical University, Oita, Japan
    Cells Tissues Organs 169:49-54. 2001
  10. ncbi request reprint Zoonotic onchocerciasis caused by a parasite from wild boar in Oita, Japan. A comprehensive analysis of morphological characteristics of the worms for its diagnosis
    H Takaoka
    Department of Infectious Disease Control, Oita University, Hasama cho, Oita 879 5593, Japan
    Parasite 11:285-92. 2004

Collaborators

Detail Information

Publications47

  1. doi request reprint Alteration of SMAD4 does not participate in tumorigenesis of adenoid cystic carcinoma of the salivary gland
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita Universeity, Oita 879 5593, Japan
    Mol Med Report 2:13-5. 2009
    ..In conclusion, the infrequent LOH of the SMAD4 gene locus and lack of SMAD4 mutations indicate that SMAD4 does not play a role in the tumorigenesis of adenoid cystic carcinoma of the salivary gland...
  2. doi request reprint Aberrant methylation in promoter regions of cyclin-dependent kinase inhibitor genes in adenoid cystic carcinoma of the salivary gland
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    APMIS 116:21-6. 2008
    ..8% in p15, 90.3% in p18, 78.8% in p19, 92.3% in p21, and 26.5% in p27). Cell cycle disruption induced by these epigenetic aberrations might be important in the tumorigenesis of ACC...
  3. ncbi request reprint Mutations in components of the Wnt signaling pathway in adenoid cystic carcinoma
    Tsutomu Daa
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Mod Pathol 17:1475-82. 2004
    ....
  4. ncbi request reprint Expression of beta-catenin, E-cadherin and cyclin D1 in adenoid cystic carcinoma of the salivary gland
    T Daa
    Dept of Pathology, Oita Medical University, Oita, Japan
    J Exp Clin Cancer Res 24:83-7. 2005
    ....
  5. ncbi request reprint Epithelial-myoepithelial carcinoma harboring p53 mutation
    T Daa
    1st Department of Pathology, Oita Medical University, Japan
    APMIS 109:316-20. 2001
    ..To our knowledge, this is the first report of a mutation in the p53 gene in an epithelial-myoepithelial carcinoma of the salivary gland...
  6. ncbi request reprint Expression of vascular endothelial growth factor and its receptors in the developing rat lung
    A Marszalek
    First Department of Pathology, Oita Medical University, Hasama machi, Oita Gun, Oita, 879 5593 Japan
    Jpn J Physiol 51:313-8. 2001
    ..The present studies revealed that VEGF and its two receptors are upregulated during the development of capillaries in the fetal and newborn rat lung...
  7. ncbi request reprint Cytoplasmic biotin-like activity interferes with immunohistochemical analysis of thyroid lesions: a comparison of antigen retrieval methods
    K Kashima
    Department of Pathology, Oita Medical University, Japan
    Mod Pathol 10:515-9. 1997
    ....
  8. ncbi request reprint The Wnt-signaling pathway is not implicated in tumorigenesis of Merkel cell carcinoma
    Shuang Liu
    First Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    J Cutan Pathol 34:22-6. 2007
    ..However, similar aberrations have not been described in Merkel cell carcinoma (MCC). The aim of this study was to determine the status of the Wnt-signaling pathway in MCC...
  9. ncbi request reprint Quantitative immunohistochemical analysis of the expression of CD31 during lung development in the rat
    A Marszalek
    First Department of Pathology, Oita Medical University, Oita, Japan
    Cells Tissues Organs 169:49-54. 2001
    ..The amount of chromogen (OD) decreased from fetal day 19 to 5 days after delivery and then increased again. The decrease in the level of expression of CD31 on days 3 and 5 after delivery was significant (p < 0.0001)...
  10. ncbi request reprint Zoonotic onchocerciasis caused by a parasite from wild boar in Oita, Japan. A comprehensive analysis of morphological characteristics of the worms for its diagnosis
    H Takaoka
    Department of Infectious Disease Control, Oita University, Hasama cho, Oita 879 5593, Japan
    Parasite 11:285-92. 2004
    ..d. japonica. Four of the 10 zoonotic cases of onchocerciasis reported worldwide were from Oita, three of them being caused by O. d. japonica, the prevalence of which in local wild boar was 22 of 24 (92%)...
  11. ncbi request reprint Solitary fibrous tumor of the thyroid gland: report of two cases and review of the literature
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu, and Department of Otolaryngology, Nankai Hospital, Saiki, Japan
    Pathol Int 56:471-7. 2006
    ..Although recurrence or metastasis has not been described in any reported cases, the clinical behavior of SFT is still undetermined, therefore long-term follow up seems necessary at present...
  12. ncbi request reprint Expression of Polo-Like Kinase (PLK1) in non-Hodgkin's lymphomas
    Katsuhiko Mito
    Department of Pathology, Faculty of Medicine, Oita University, Japan
    Leuk Lymphoma 46:225-31. 2005
    ..Our study demonstrates that expression of PLK1 might reflect the malignant potential of NHLs and that PLK1 might be more useful than Ki-67 for the detection of proliferative cells...
  13. doi request reprint Analysis of p53 mutations and the expression of p53 and p21WAF1/CIP1 protein in 15 cases of sebaceous carcinoma of the eyelid
    Kunihiro Kiyosaki
    Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Invest Ophthalmol Vis Sci 51:7-11. 2010
    ....
  14. doi request reprint Merkel cell carcinoma co-existent with sebaceous carcinoma of the eyelid
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu, Oita, Japan
    J Cutan Pathol 36:983-6. 2009
    ..Metastatic deposits were identified in the regional lymph nodes, which solely consisted of Merkel cell carcinoma without sebaceous carcinoma. This is the first report of such co-existent lesions...
  15. ncbi request reprint Biotin-rich intranuclear inclusions in morule-lacking adenocarcinoma of the gallbladder: a new category of "neoplastic/non-morular" lesions
    Yasuhiko Kimura
    Department of Pathology, Faculty of Medicine, Oita University, Hasama machi, 879 5593, Oita, Japan
    Virchows Arch 446:194-9. 2005
    ..Our cases are the first neoplastic lesions with biotin-rich intranuclear inclusions that lacked morular structures. We propose a new "neoplastic/non-morular" category for lesions with biotin-rich intranuclear inclusions...
  16. ncbi request reprint Multiple calcifying fibrous tumors of the pleura
    Katsuhiko Mito
    Department of Pathology, Faculty of Medicine, Oita University, Hasama machi, 879 5593 Oita, Japan
    Virchows Arch 446:78-81. 2005
    ..We made a histological diagnosis of CFT of the pleura, and the patient remains well 6 months after the wedge resection...
  17. ncbi request reprint An Onchocerca species of wild boar found in the subcutaneous nodule of a resident of Oita, Japan
    Hiroyuki Takaoka
    Department of Infectious Disease Control, Faculty of Medicine, Oita University, Hasama cho, Oita 879 5593, Japan
    Parasitol Int 54:91-3. 2005
    ..Jointed with previous reports in the past decade, this case confirms the occasional transmission of the parasite from wild boar to humans in Oita...
  18. ncbi request reprint Herpes simplex infection in urothelial carcinoma
    Naomi Kaku
    Department of Pathology, Faculty of Medicine, Oita University, Hasama machi, 879 5593, Oita, Japan
    Virchows Arch 445:68-73. 2004
    ..Our findings indicate that UCs become infected with HSV much more easily than non-neoplastic urothelium...
  19. ncbi request reprint Porocarcinoma arising in pigmented hidroacanthoma simplex
    Tetsuya Ueo
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Am J Dermatopathol 27:500-3. 2005
    ..We considered this portion of the tumor to be a porocarcinoma. Since the two portions of the tumor were continuous, we made a final diagnosis of porocarcinoma arising in pre-existing pigmented HAS with amyloid deposition...
  20. ncbi request reprint Immunohistochemical analysis of morules in colonic neoplasms: morules are morphologically and qualitatively different from squamous metaplasia
    Tetsuya Ueo
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    Pathobiology 72:269-78. 2005
    ..We consider that morules in colonic neoplasms are cell clusters with a basal/stem cell phenotype, and have less proliferative and less invasive potential than other cancer cells...
  21. doi request reprint A case of sebaceoma with extensive apocrine differentiation
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu Shi, Oita, Japan
    Am J Dermatopathol 30:408-11. 2008
    ..Nuclear atypia of all types of cells was inconspicuous, and mitotic figures were infrequent. We considered the lesion to be a sebaceoma with apocrine differentiation...
  22. ncbi request reprint Florid cystic endosalpingiosis of the spleen
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu City, Oita, Japan
    APMIS 114:393-8. 2006
    ..Regarding etiology, it was considered to derive from the secondary müllerian system of the splenic capsule...
  23. ncbi request reprint Genetic alterations in 102 primary gastric cancers by comparative genomic hybridization: gain of 20q and loss of 18q are associated with tumor progression
    Yasuhiko Kimura
    Department of Oncological Science Pathology, Faculty of Medicine, Oita University, Oita 879 5593, Japan
    Mod Pathol 17:1328-37. 2004
    ..These data suggest that gain of 20q and loss of 18q might play an important role in the development and progression of gastric cancer. Moreover, some genes on 20q and 18q might be target genes of gastric cancer...
  24. ncbi request reprint Localized peribronchial adenomyomatous hyperplasia arising from an ectatic bronchus with aspergilloma
    Katsuhiko Mito
    Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
    APMIS 112:218-21. 2004
    ..This condition should be recognized as a tumor-like form of smooth muscle hyperplasia induced by bronchiectasis and inflammation...
  25. ncbi request reprint Phlebosclerotic colitis coincident with carcinoma in adenoma
    Yasuhiko Kimura
    First Department of Pathology, Oita Medical University and San ai Hospital, Oita, Japan
    Pathol Int 53:721-5. 2003
    ..A small polypoid lesion was also found in the affected region and was diagnosed histologically as carcinoma in adenoma. To our knowledge, this is the first reported case of phlebosclerotic colitis complicated by carcinoma...
  26. ncbi request reprint Mild hypothermia reduces expression of intercellular adhesion molecule-1 (ICAM-1) and the accumulation of neutrophils after acid-induced lung injury in the rat
    S Kira
    1st Department of Pathology, Oita University Faculty of Medicine, Hasama machi, Oita, Japan
    Acta Anaesthesiol Scand 49:351-9. 2005
    ..We studied the effects of mild hypothermia on the expression of ICAM-1 and the accumulation of neutrophils after AILI in the rat...
  27. ncbi request reprint Myxoid adrenal cortical adenoma
    K Honda
    Department of Pathology, Oita Medical University, Oita, Japan
    Pathol Int 51:887-91. 2001
    ....
  28. ncbi request reprint Preferential transcription of a gene for alpha amylase in the carcinoid tumor of African rodent Mastomys natalensis
    T Daa
    First Dept of Pathology, Oita Medical University, Japan
    J Exp Clin Cancer Res 21:131-6. 2002
    ..Immunohistochemical staining revealed alpha-amylase in the cytoplasm of Mastomys carcinoid tumors. Our results demonstrated that an exocrine enzyme 'amylase' could be produced ectopically by a neuroen docrine tumor...
  29. ncbi request reprint Carcinosarcoma of the parotid gland: an unusual case with large-cell neuroendocrine carcinoma and rhabdomyosarcoma
    T Ueo
    Department of Pathology, Faculty of Medicine, Oita University, Hasama machi, Oita, Japan
    APMIS 113:456-64. 2005
    ..With regard to histopathogenesis, based on the lack of histopathological evidence and antecedent history of pleomorphic adenoma, we considered the present case to be de novo, not expleomorphic adenoma...
  30. ncbi request reprint Aberrant intranuclear localization of biotin, biotin-binding enzymes, and beta-catenin in pregnancy-related endometrium and morule-associated neoplastic lesions
    Ayako Gamachi
    Department of Pathology, Oita Medical University, Oita, Japan
    Mod Pathol 16:1124-31. 2003
    ....
  31. ncbi request reprint Detection of disseminated cancer cells in rib marrow of patients with esophageal cancer
    Tsuyoshi Noguchi
    Department of Oncological Science Surgery II, Oita Medical University, Idaigaoka 1 1, Hasama machi, Oita 879 5593, Japan
    Oncol Rep 10:623-7. 2003
    ..However, combined analysis using plural markers should be required since sensitivity or specificity of each marker may vary. Further follow-up of the patients is necessary to clarify the clinical impact of micrometastasis in rib marrow...
  32. ncbi request reprint Expression of CD10 in basal cell carcinoma
    Kazuhiro Yada
    Department of Pathology, Faculty of Medicine, Oita University, Oita 879 5593, Japan
    Am J Dermatopathol 26:463-71. 2004
    ..CD10 might be an indicator of tumor invasiveness if it is expressed in stromal cells, while it might be a marker of follicular differentiation if it is expressed in the actual tumor cells of cutaneous epithelial neoplasms...
  33. doi request reprint Mutational analysis of Wnt signaling molecules in ameloblastoma with aberrant nuclear expression of beta-catenin
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu Shi, Japan
    J Oral Pathol Med 37:565-70. 2008
    ..To clarify the genetic background of ameloblastoma, expression of beta-catenin, and mutational status of genes involved in Wnt signaling pathway were investigated...
  34. ncbi request reprint Melanotic oncocytic metaplasia of the nasopharynx: a report of seven cases and review of the literature
    Mika Sakaki
    Department of Pathology, University of Tokushima School of Medicine, 3 18 15 Kuramoto cho, 770 8503 Tokushima, Japan
    Virchows Arch 444:345-9. 2004
    ..The recognition of melanotic oncocytic metaplasia is of clinical importance, as it may be misdiagnosed as a malignancy to the unwary...
  35. ncbi request reprint Coexistence of Epstein-Barr virus-associated gastric carcinoma with malignant lymphoma: report of two cases
    Tetsuya Ueo
    Department of Pathology, Faculty of Medicine, Oita University, Hasama machi, Oita 879 5593, Japan
    Virchows Arch 449:215-9. 2006
    ..The present cases suggest that focal immunosuppression by adjacent gastric lymphomas might be related to the alteration of the microenvironment and development of EBV-GC...
  36. ncbi request reprint Immunohistochemical localization of pyruvate carboxylase and carbamyl-phosphate synthetase I in normal and neoplastic human pancreatic tissues
    Tetsuro Sato
    Department of Pathology, Oita Medical University, Oita, Japan
    Pancreas 25:130-5. 2002
    ..It has been suggested that pyruvate carboxylase (PC) and carbamyl-phosphate synthetase I (CPS I) might be colocalized with carbonic anhydrase V (CA V), which is generally considered to provide HCO3- ions for PC and CPS I...
  37. ncbi request reprint Detection of HTLV-1 gene on cytologic smear slides
    Kenji Kashima
    Department of Pathology, Oita University, Oita, Japan
    Methods Mol Biol 304:183-9. 2005
    ..Although this method does not provide proof of the monoclonal integration of HTLV-1 genes, it can be applied when adult T-cell leukemia/lymphoma is suspected cytologically but fresh samples for Southern blotting are unavailable...
  38. ncbi request reprint Detection of the HTLV-I gene on cytologic smear slides
    Kenji Kashima
    Department of Pathology, Oita Medical University Hospital, First Department of Pathology, Oita Medical University, Oita, Japan
    Acta Cytol 46:709-12. 2002
    ..To apply the polymerase chain reaction (PCR) for detection of the HTLV-I gene from cytologic smear slides...
  39. ncbi request reprint Human intestinal spirochetosis in Japan; its incidence, clinicopathologic features, and genotypic identification
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu, Japan
    Mod Pathol 21:76-84. 2008
    ..In addition, we emphasize a usefulness of immunostaining with anti-Treponema pallidum and anti-Mycobacterium bovis polyclonal antibodies for detecting the spirochetes...
  40. ncbi request reprint A case of cutaneous myoepithelial carcinoma
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu City, Japan
    J Cutan Pathol 34:648-53. 2007
    ....
  41. ncbi request reprint The ectopic expression of gastric mucin in extramammary and mammary Paget's disease
    Yoshiyuki Kondo
    Department of Pathology, Oita Medical University, Oita, Japan
    Am J Surg Pathol 26:617-23. 2002
    ..The ectopic localization of mucosubstances may be a further step in the understanding of these lesions. Moreover, antibodies against MUC1 seem to be a useful tool for the diagnosis of both ExMPD and MPD...
  42. ncbi request reprint Coexistent multiple adenocarcinomas arising in Barrett's esophagus 23 years after total gastrectomy and esophageal small cell carcinoma
    Tsuyoshi Noguchi
    Department of Oncological Science Surgery II, Oita Medical University, Hasama machi, Oita, Japan
    Jpn J Thorac Cardiovasc Surg 51:259-62. 2003
    ..This case is indicative of the high and totipotential carcinogenetic risk of Barrett's epithelium and the relationship between duodenal content reflux and esophageal carcinogenesis after total gastrectomy...
  43. ncbi request reprint Carcinosarcoma ex recurrent pleomorphic adenoma of the submandibular gland
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu, Japan
    APMIS 115:789-94. 2007
    ..Based on the clinical history and histopathology, we consider the lesion to have originated from recurrent pleomorphic adenoma...
  44. ncbi request reprint FHIT expression and hypermethylation in esophageal squamous cell carcinoma
    Tsuyoshi Noguchi
    Surgery, Department of Oncological Science, Oita Medical University, Oita, Japan
    Int J Mol Med 11:441-7. 2003
    ..FHIT gene expression was closely correlated with cancer progression, as indicated by tumor invasion and lymphatic spread, and it may provide insight into the mechanism of progression of esophageal cancer...
  45. ncbi request reprint Multiple spindle cell lipomas of the tongue: report of a case
    Naomi Kaku
    Department of Pathology, Oita Medical University, Oita, Japan
    APMIS 111:581-5. 2003
    ..Immunohistochemical analysis revealed that the spindle cells were strongly positive for CD 34 and bcl-2. To our knowledge, this is the first report of a case of multiple SCLs of the tongue...
  46. doi request reprint Pulmonary myoepithelial carcinoma resembling matrix-producing carcinoma of the breast: case report and review of the literature
    Jin Tanahashi
    Department of Pathology, Faculty of Medicine, Oita University, Yufu, Japan
    APMIS 118:401-6. 2010
    ..The patient developed multiple brain metastases, and died of the disease 11 months after the surgery. In this report, we discuss the histopathologic uniqueness of the present case together with a review of the literature...
  47. ncbi request reprint Primary pulmonary synovial sarcoma: a clinicopathologic, immunohistochemical, and molecular study of 11 cases
    Sumika Okamoto
    Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
    Hum Pathol 35:850-6. 2004
    ..5 years. In conclusion, PSS tends to occur in older patients and shows an aggressive behavior probably due to its anatomical location and large tumor often resulting in incomplete resection and high proliferative activity...