Naoki Ohtsu

Summary

Country: Japan

Publications

  1. pmc Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability
    Nanako Awai-Kasaoka
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Mol Vis 19:1332-40. 2013
  2. doi request reprint Elevated levels of multiple biomarkers of Alzheimer's disease in the aqueous humor of eyes with open-angle glaucoma
    Toshihiro Inoue
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Invest Ophthalmol Vis Sci 54:5353-8. 2013
  3. doi request reprint Rho-associated kinase inhibitors: a novel glaucoma therapy
    Toshihiro Inoue
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1 1 1, Honjo, Kumamoto, Japan Electronic address
    Prog Retin Eye Res 37:1-12. 2013
  4. doi request reprint Prognostic risk factors for failure of trabeculectomy with mitomycin C after vitrectomy
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Japan
    Jpn J Ophthalmol 56:464-9. 2012
  5. doi request reprint Simultaneous increases in multiple proinflammatory cytokines in the aqueous humor in pseudophakic glaucomatous eyes
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    J Cataract Refract Surg 38:1389-97. 2012
  6. ncbi request reprint Loss of vision due to a physiologic pituitary enlargement during normal pregnancy
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Japan
    Graefes Arch Clin Exp Ophthalmol 245:1049-51. 2007
  7. doi request reprint Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Kumamoto University, Graduate School of Medical Sciences, Kumamoto, Japan
    FEBS Lett 584:3233-8. 2010
  8. ncbi request reprint Identification of a population of cells with hematopoietic stem cell properties in mouse aorta-gonad-mesonephros cultures
    Ikuo Nobuhisa
    Division of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2 2 1 Honjo, Kumamoto, Japan
    Exp Cell Res 313:965-74. 2007
  9. pmc p38 MAP Kinase Inhibitor Suppresses Transforming Growth Factor-β2-Induced Type 1 Collagen Production in Trabecular Meshwork Cells
    Miyuki Inoue-Mochita
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    PLoS ONE 10:e0120774. 2015
  10. ncbi request reprint Inhibitory effects of homeodomain-interacting protein kinase 2 on the aorta-gonad-mesonephros hematopoiesis
    Naoki Ohtsu
    Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan
    Exp Cell Res 313:88-97. 2007

Collaborators

Detail Information

Publications10

  1. pmc Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability
    Nanako Awai-Kasaoka
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Mol Vis 19:1332-40. 2013
    ..To clarify the primary oxidative stress response signaling pathways in trabecular meshwork (TM) cells and their effects on cell viability...
  2. doi request reprint Elevated levels of multiple biomarkers of Alzheimer's disease in the aqueous humor of eyes with open-angle glaucoma
    Toshihiro Inoue
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    Invest Ophthalmol Vis Sci 54:5353-8. 2013
    ..To investigate levels of biomarkers of Alzheimer's disease in the aqueous humor in patients with open-angle glaucoma (OAG)...
  3. doi request reprint Rho-associated kinase inhibitors: a novel glaucoma therapy
    Toshihiro Inoue
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1 1 1, Honjo, Kumamoto, Japan Electronic address
    Prog Retin Eye Res 37:1-12. 2013
    ..All evidence indicates that aqueous humor outflow is affected by cytoskeleton physiology and this information may provide valuable insight into understanding glaucoma pathology and treatment...
  4. doi request reprint Prognostic risk factors for failure of trabeculectomy with mitomycin C after vitrectomy
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Japan
    Jpn J Ophthalmol 56:464-9. 2012
    ..To evaluate the prognostic risk factors for failure of trabeculectomy with mitomycin C (MMC) in vitrectomized eyes...
  5. doi request reprint Simultaneous increases in multiple proinflammatory cytokines in the aqueous humor in pseudophakic glaucomatous eyes
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    J Cataract Refract Surg 38:1389-97. 2012
    ..To evaluate cytokine and growth factor levels in the aqueous humor in patients with open-angle glaucoma (OAG)...
  6. ncbi request reprint Loss of vision due to a physiologic pituitary enlargement during normal pregnancy
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, 1 1 1 Honjo, Kumamoto, Japan
    Graefes Arch Clin Exp Ophthalmol 245:1049-51. 2007
    ..Physiologic pituitary enlargement during normal pregnancy is well known, but we are unaware of previous reports on a natural course of visual loss due to this disease...
  7. doi request reprint Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis
    Toshihiro Inoue
    Department of Ophthalmology and Visual Science, Kumamoto University, Graduate School of Medical Sciences, Kumamoto, Japan
    FEBS Lett 584:3233-8. 2010
    ..These data indicate that Hipk1 and Hipk2 are involved in regulation of eye size, lens formation and retinal lamination during late embryogenesis...
  8. ncbi request reprint Identification of a population of cells with hematopoietic stem cell properties in mouse aorta-gonad-mesonephros cultures
    Ikuo Nobuhisa
    Division of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2 2 1 Honjo, Kumamoto, Japan
    Exp Cell Res 313:965-74. 2007
    ..These results indicate that CD45(low) c-Kit(+) cells from the AGM culture have the potential to reconstitute multi-lineage hematopoietic cells...
  9. pmc p38 MAP Kinase Inhibitor Suppresses Transforming Growth Factor-β2-Induced Type 1 Collagen Production in Trabecular Meshwork Cells
    Miyuki Inoue-Mochita
    Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
    PLoS ONE 10:e0120774. 2015
    ..Collectively, TGF-β2-induced production of type 1 collagen is suppressed by p38 inhibition and accompanied by partial inactivation of Smad2/3, in human trabecular meshwork cells. ..
  10. ncbi request reprint Inhibitory effects of homeodomain-interacting protein kinase 2 on the aorta-gonad-mesonephros hematopoiesis
    Naoki Ohtsu
    Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan
    Exp Cell Res 313:88-97. 2007
    ..These data indicate that HIPK2 plays a negative regulatory role in AGM hematopoiesis in the mouse embryo...