H Ohbayashi

Summary

Country: Japan

Publications

  1. ncbi request reprint One-year evaluation of the preventative effect of hydrofluoroalkane-beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Mizunami, Gifu Pref 509 6101, Japan
    Respiration 74:146-53. 2007
  2. ncbi request reprint Pitavastatin improves serum resistin levels in patients with hypercholesterolemia
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, 76 1 Toki Cho, Mizunami City, Gifu, Japan
    J Atheroscler Thromb 15:87-93. 2008
  3. ncbi request reprint Hydrofluoroalkane-beclomethasone dipropionate effectively improves airway eosinophilic inflammation including the distal airways of patients with mild to moderate persistent asthma as compared with fluticasone propionate in a randomized open double-cross
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Gifu, Japan
    Allergol Int 57:231-9. 2008
  4. ncbi request reprint [The evaluation of the distal airway inflammation of well controlled asthmatic patients using sputum induction by inhalation of 10% hypertonic saline for 15 minutes]
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital
    Arerugi 57:1000-11. 2008
  5. pmc Pretreatment with inhaled procaterol improves symptoms of dyspnea and quality of life in patients with severe COPD
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Gifu
    Int J Gen Med 5:517-24. 2012
  6. doi request reprint Influence of dentures on residual inhaled corticosteroids in the mouths of elderly asthma patients
    Hiroyuki Ohbayashi
    Department of Respiratory and Allergy Internal Medicine, Tohno Chuo Clinic, 1 14 1, Matsugase Cho, Mizunami City, Gifu 509 6134, Japan
    Respir Investig 50:54-61. 2012
  7. doi request reprint Additional effects of pranlukast in salmeterol/fluticasone combination therapy for the asthmatic distal airway in a randomized crossover study
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, 76 1 Toki Cho, Mizunami City, Gifu Pref 509 6101, Japan
    Pulm Pharmacol Ther 22:574-9. 2009
  8. ncbi request reprint Pitavastatin improves plasma pentraxin 3 and arterial stiffness in atherosclerotic patients with hypercholesterolemia
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, Gifu, Japan
    J Atheroscler Thromb 16:490-500. 2009
  9. doi request reprint Current situation of asthma therapy by allergists in primary medical facilities in Japan
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Tohno Kousei Hospital, Gifu, Japan
    Allergol Int 59:355-62. 2010
  10. doi request reprint Pitavastatin - a novel therapeutic milestone
    H Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, Toki Cho Mizunami City, Japan
    Drugs Today (Barc) 46:765-75. 2010

Detail Information

Publications21

  1. ncbi request reprint One-year evaluation of the preventative effect of hydrofluoroalkane-beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Mizunami, Gifu Pref 509 6101, Japan
    Respiration 74:146-53. 2007
    ..In asthmatic patients with eosinophilic inflammation of the peripheral airways, appropriate drug delivery to the affected area is required...
  2. ncbi request reprint Pitavastatin improves serum resistin levels in patients with hypercholesterolemia
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, 76 1 Toki Cho, Mizunami City, Gifu, Japan
    J Atheroscler Thromb 15:87-93. 2008
    ..This clinical study aimed to investigate whether pitavastatin can regulate the serum level of resistin, together with levels of other inflammatory cytokines and adipocytokines...
  3. ncbi request reprint Hydrofluoroalkane-beclomethasone dipropionate effectively improves airway eosinophilic inflammation including the distal airways of patients with mild to moderate persistent asthma as compared with fluticasone propionate in a randomized open double-cross
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Gifu, Japan
    Allergol Int 57:231-9. 2008
    ..To evaluate whether hydrofluoroalkane-beclomethasone dipropionate (HFA-BDP) controls eosinophilic inflammation, including that in the distal airways, more effectively than fluticasone propionate (FP) Diskus...
  4. ncbi request reprint [The evaluation of the distal airway inflammation of well controlled asthmatic patients using sputum induction by inhalation of 10% hypertonic saline for 15 minutes]
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital
    Arerugi 57:1000-11. 2008
    ....
  5. pmc Pretreatment with inhaled procaterol improves symptoms of dyspnea and quality of life in patients with severe COPD
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, Gifu
    Int J Gen Med 5:517-24. 2012
    ..The aim of this study was to investigate the clinical effect of supplementary inhaled procaterol hydrochloride in patients with COPD...
  6. doi request reprint Influence of dentures on residual inhaled corticosteroids in the mouths of elderly asthma patients
    Hiroyuki Ohbayashi
    Department of Respiratory and Allergy Internal Medicine, Tohno Chuo Clinic, 1 14 1, Matsugase Cho, Mizunami City, Gifu 509 6134, Japan
    Respir Investig 50:54-61. 2012
    ..The influence of dentures on residual inhaled corticosteroids (ICSs) in the mouths of elderly asthmatic patients and the appropriate time for gargling after inhaling ICSs are unclear...
  7. doi request reprint Additional effects of pranlukast in salmeterol/fluticasone combination therapy for the asthmatic distal airway in a randomized crossover study
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Medicine, Tohno Kousei Hospital, 76 1 Toki Cho, Mizunami City, Gifu Pref 509 6101, Japan
    Pulm Pharmacol Ther 22:574-9. 2009
    ..Salmeterol/fluticasone combination (SFC) therapy is used to control inflammation in the distal airway of patients with well-controlled asthma, but the efficacy of this approach is unclear...
  8. ncbi request reprint Pitavastatin improves plasma pentraxin 3 and arterial stiffness in atherosclerotic patients with hypercholesterolemia
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, Gifu, Japan
    J Atheroscler Thromb 16:490-500. 2009
    ..To investigate the effect of pitavastatin on asymptomatic atherosclerosis in patients with hypercholesterolemia...
  9. doi request reprint Current situation of asthma therapy by allergists in primary medical facilities in Japan
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Tohno Kousei Hospital, Gifu, Japan
    Allergol Int 59:355-62. 2010
    ..The present study was conducted because specialists are responsible for increasing the use of guidelines, but the current state of asthma care provided by specialists in primary clinical settings has not been clarified...
  10. doi request reprint Pitavastatin - a novel therapeutic milestone
    H Ohbayashi
    Department of Internal Medicine, JA Gifu Tohno Kousei Hospital, Toki Cho Mizunami City, Japan
    Drugs Today (Barc) 46:765-75. 2010
    ..This review clarifies the long-term lipid-lowering and antiatherosclerotic effects of pitavastatin...
  11. ncbi request reprint [A multicenter, open-label, randomized comparison of suppressive effects on asthmatic inflammation of lower airways and improved effects on health-related QOL between HFA-BDP and fluticasone propionate]
    Hiroyuki Ohbayashi
    Tohno Kousei Hospital, Japan
    Arerugi 56:577-86. 2007
    ....
  12. ncbi request reprint Neutrophil elastase inhibitors as treatment for COPD
    Hiroyuki Ohbayashi
    Internal Medicine II, Nagoya University School of Medicine, 65, Tsurumai cho, Showa Ku, Nagoya City, 466 8550, Japan
    Expert Opin Investig Drugs 11:965-80. 2002
    ..In this review, various problems that remain to be solved in the clinical use of human neutrophil elastase inhibitors are discussed...
  13. ncbi request reprint [The evaluation of the relationship between the residual fluticasone propionate dry powder after inhalation and maximum peak inspiratory flow]
    Hiroyuki Ohbayashi
    JA Gifu Kouseiren Showa Hospital
    Arerugi 51:544-51. 2002
    ..In this study, we evaluated the relationship between residual powder and peak inspiratory flow (PIF), and the therapeutic necessity of using the reductive method of the residual powder...
  14. ncbi request reprint Matrix metalloproteinases in lung diseases
    Hiroyuki Ohbayashi
    Nagoya University, School of Med, Japan
    Curr Protein Pept Sci 3:409-21. 2002
    ..In this review, the main focus is on the recent clinical and experimental findings and the contributions of MMPs and/or TIMPs in the lung diseases...
  15. ncbi request reprint [An evaluation of the acceptance of budesonide turbuhaler by older Japanese patients with bronchial asthma when changed from fluticasone propionate (FP) or beclomethasone dipropionate (BDP)]
    Hiroyuki Ohbayashi
    Internal Medicine, JA Gifu Showa Hospital
    Arerugi 52:31-8. 2003
    ..This study was accordingly designed to evaluate the acceptability and clinical efficacy of budesonide in older Japanese patients with bronchial asthma...
  16. ncbi request reprint [The small airway inflammation of asthmatic patients who have used dry powder type inhaled steroid for moderate-long term evaluated by induced sputum and the efficacy of HFA-BDP (QVAR) inhalation]
    Hiroyuki Ohbayashi
    Internal Medicine, JA Gifu Thono Kousei Hospital
    Arerugi 54:24-35. 2005
    ..We also investigated the effect of Hydrofluoroalukan-beclomethasone dipropionate (HFA-BDP), a new type of inhaled steroid which forms super micro aerosol particles, in the distal small airway...
  17. ncbi request reprint Matrix metalloproteinase-9 and airway remodeling in asthma
    Hiroyuki Ohbayashi
    Division of Respiratory Medicine, Department of Medicine, Nagoya University Graduate School of Medicine, 65, Nagoya City, Aichi Pref 466 8560, Japan
    Curr Drug Targets Inflamm Allergy 4:177-81. 2005
    ..This review also refers to the partial contribution of nitric oxide to MMP-9 in asthma...
  18. ncbi request reprint [A case of severe persistent bronchial asthma who showed significant improvement by switching to hfa-bdp, with reducing the dosage of oral steroids]
    Hiroyuki Ohbayashi
    Internal Medicine, JA Gifu Tohno Kousei Hospital
    Arerugi 54:1294-301. 2005
    ..In this case study, it was suggested that HFA-BDP may reduce eosinophilic inflammation remained in the peripheral airway, and may be effective in supplementing the activity of PSL which must be taken orally by severe asthmatic patients...
  19. ncbi request reprint ZD-0892 AstraZeneca
    H Ohbayashi
    Nagoya University School of Medicine, Second Department of Internal Medicine, 86 Toki Cho, Mizunami City, Gifu Prefecture, Japan
    Curr Opin Investig Drugs 1:227-9. 2000
    ..The compound was originally under investigation for the potential treatment of asthma, but development was discontinued for this indication [266604]. The compound is the follow-up to ZD-8321 (qv) [336599]...
  20. ncbi request reprint [Examination of beneficial effects of risedronate in improving quality of life during long-term treatment of primary osteoporosis]
    Hiroyuki Ohbayashi
    Department of Internal Medicine, JA Gifu Kouseiren, Tohno Kousei Hospital
    Nihon Rinsho 67:206-12. 2009
    ..The aim of this study was to evaluate the therapeutic effect of long-term treatment with risedronate on the time-course of changes in patients' QOL...
  21. ncbi request reprint [Results of a survey questionnaire concerning smoking conditions in 54 major Japanese pharmaceutical companies and among their employees]
    Hiroyuki Ohbayashi
    Department of Allergy and Respiratory Disease, Tohno Kousei Hospital
    Nihon Kokyuki Gakkai Zasshi 44:374-83. 2006
    ..As few broad studies of the actual smoking conditions in pharmaceutical companies and among their employees have been conducted, this issue warrants investigation...