T Urashima

Summary

Affiliation: Obihiro University of Agriculture and Veterinary Medicine
Country: Japan

Publications

  1. ncbi request reprint Chemical characterization of milk oligosaccharides of the Japanese black bear, Ursus thibetanus japonicus
    T Urashima
    Department of Bio Resource Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Biochim Biophys Acta 1472:290-306. 1999
  2. ncbi request reprint Sialyllactose occurs as free lactones in ovine colostrum
    T Nakamura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Hokkaido, Obihiro, 080 8555, Japan
    Biochim Biophys Acta 1381:286-92. 1998
  3. ncbi request reprint Characterization of oligosaccharides in milk of a mink, Mustela vison
    Tadasu Urashima
    Graduate School of Hood Hydiene, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol A Mol Integr Physiol 142:461-71. 2005
  4. ncbi request reprint Inhibition of influenza-virus-induced cytopathy by sialylglycoconjugates
    Takashi Terabayashi
    Department of Physics, School of Science, Kitasato University, 1 15 1 Kitasato, Sagamihara 228 8555, Japan
    Carbohydr Res 341:2246-53. 2006
  5. ncbi request reprint Structural determination of the oligosaccharides in the milk of an Asian elephant (Elephas maximus)
    Yusuke Uemura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol A Mol Integr Physiol 145:468-78. 2006
  6. doi request reprint Chemical characterization of milk oligosaccharides of the koala (Phascolarctos cinereus)
    Tadasu Urashima
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Glycoconj J 30:801-11. 2013
  7. ncbi request reprint Recent advances in studies on milk oligosaccharides of cows and other domestic farm animals
    Tadasu Urashima
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Biosci Biotechnol Biochem 77:455-66. 2013
  8. pmc The predominance of type I oligosaccharides is a feature specific to human breast milk
    Tadasu Urashima
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Adv Nutr 3:473S-82S. 2012
  9. doi request reprint Evolution of milk oligosaccharides and lactose: a hypothesis
    T Urashima
    Department of Animal Hygiene, Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Animal 6:369-74. 2012
  10. pmc Chemical characterization of oligosaccharides in the milk of six species of New and Old World monkeys
    Kohta Goto
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Glycoconj J 27:703-15. 2010

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Chemical characterization of milk oligosaccharides of the Japanese black bear, Ursus thibetanus japonicus
    T Urashima
    Department of Bio Resource Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Biochim Biophys Acta 1472:290-306. 1999
    ..B-pentasaccharide was a dominant saccharide in early lactation milk, while alpha 3'-galactosyllactose was dominant in milk, later. The milk oligosaccharides of the Japanese black bear were compared with those of the Ezo brown bear...
  2. ncbi request reprint Sialyllactose occurs as free lactones in ovine colostrum
    T Nakamura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Hokkaido, Obihiro, 080 8555, Japan
    Biochim Biophys Acta 1381:286-92. 1998
    ..In this study, Neu5Gc-lactose lactones, in their free form, have been isolated for the first time from any natural sources including milk or colostrum...
  3. ncbi request reprint Characterization of oligosaccharides in milk of a mink, Mustela vison
    Tadasu Urashima
    Graduate School of Hood Hydiene, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol A Mol Integr Physiol 142:461-71. 2005
    ..Some of the neutral and acidic oligosaccharides, determined here, had been found also in harbour seal milk, but the harbour seal oligosaccharides did not contain alpha(1-3)-linked Gal residues...
  4. ncbi request reprint Inhibition of influenza-virus-induced cytopathy by sialylglycoconjugates
    Takashi Terabayashi
    Department of Physics, School of Science, Kitasato University, 1 15 1 Kitasato, Sagamihara 228 8555, Japan
    Carbohydr Res 341:2246-53. 2006
    ....
  5. ncbi request reprint Structural determination of the oligosaccharides in the milk of an Asian elephant (Elephas maximus)
    Yusuke Uemura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol A Mol Integr Physiol 145:468-78. 2006
    ..The higher oligosaccharides contained only the type II chain (Gal(beta1-4)GlcNAc); this finding differed from previously published data on Asian elephant milk oligosaccharides...
  6. doi request reprint Chemical characterization of milk oligosaccharides of the koala (Phascolarctos cinereus)
    Tadasu Urashima
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Glycoconj J 30:801-11. 2013
    ..The presence of fucosyl oligosaccharides is a significant feature of koala milk, in which it differs from milk of the tammar wallaby and the red kangaroo...
  7. ncbi request reprint Recent advances in studies on milk oligosaccharides of cows and other domestic farm animals
    Tadasu Urashima
    Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Biosci Biotechnol Biochem 77:455-66. 2013
    ..This review is concerned with recent progress in studies on the milk oligosaccharides of domestic farm animals, especially of BMOs and bovine glycoproteins, and it discusses the possibility of industrial utilization in the near future...
  8. pmc The predominance of type I oligosaccharides is a feature specific to human breast milk
    Tadasu Urashima
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Adv Nutr 3:473S-82S. 2012
    ..The biological importance of type I HMO predominance warrants further study, both in relation to human health and to human evolution...
  9. doi request reprint Evolution of milk oligosaccharides and lactose: a hypothesis
    T Urashima
    Department of Animal Hygiene, Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Animal 6:369-74. 2012
    ..It can be hypothesized that this feature may have a selective advantage in that it may promote the growth of beneficial colonic bacteria, Bifidobacteria, in the human infant colon...
  10. pmc Chemical characterization of oligosaccharides in the milk of six species of New and Old World monkeys
    Kohta Goto
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080 8555, Japan
    Glycoconj J 27:703-15. 2010
    ..Further research is needed to determine the extent to which the milk oligosaccharide patterns observed among these taxa represent wider phylogenetic trends among primates and how much variation occurs among individuals or species...
  11. ncbi request reprint Differences in oligosaccharide pattern of a sample of polar bear colostrum and mid-lactation milk
    Tadasu Urashima
    Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Hokkaido, Obihiro 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 136:887-96. 2003
    ..Isoglobotriose, which had previously been found to be a dominant saccharide in mature milk from the Ezo brown bear, the Japanese black bear and the polar bear, was not found in the polar bear colostrum...
  12. ncbi request reprint Characterization of oligosaccharides in milk of bearded seal (Erignathus barbatus)
    Tadasu Urashima
    Department of Bio Resource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 138:1-18. 2004
    ..The milk oligosaccharides of the bearded seal were compared to those of the harbour seal, which had been studied previously...
  13. ncbi request reprint Chemical characterization of sialyl oligosaccharides in milk of the Japanese black bear, Ursus thibetanus japonicus
    Tadasu Urashima
    Department of Animal Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 139:587-95. 2004
    ..Neu5Ac(alpha2-6)Gal(beta1-4)GlcNAc(beta1-3)[Gal(alpha1-3)[Fuc(alpha1-2)]Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)]Gal(beta1-4)Glc. Neu5Ac(alpha2-6)Gal(beta1-4)GlcNAc(beta1-3)[Neu5Ac(alpha2-6)Gal(beta1-4)GlcNAc(beta1-6)Gal(beta1-4)Glc...
  14. ncbi request reprint Chemical characterization of the oligosaccharides in Bryde's whale (Balaenoptera edeni) and Sei whale (Balaenoptera borealis lesson) milk
    Tadasu Urashima
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Comp Biochem Physiol B Biochem Mol Biol 146:153-9. 2007
    ....
  15. doi request reprint Chemical characterization of the oligosaccharides in Bactrian camel (Camelus bactrianus) milk and colostrum
    K Fukuda
    Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    J Dairy Sci 93:5572-87. 2010
    ..The oligosaccharides in the mature camel milk were characterized as 3'-galactosyllactose, Gal(β1-3)[Gal(β1-4)GlcNAc(β1-6)]Gal(β1-4)Glc (lacto-N-novopentaose I), and 3'-sialyllactose...
  16. ncbi request reprint Chemical characterization of the oligosaccharides in milk of high Arctic harbour seal (Phoca vitulina vitulina)
    Tadasu Urashima
    Department of Bio Resource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol A Mol Integr Physiol 135:549-63. 2003
    ..The Neu5Ac residues were found to be linked to GlcNAc or penultimate Gal residues. The acidic oligosaccharides are the first to have been characterized in the milk of any species of seal...
  17. ncbi request reprint Chemical characterisation of the oligosaccharides in hooded seal (Cystophora cristata) and Australian fur seal (Arctocephalus pusillus doriferus) milk
    T Urashima
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 128:307-23. 2001
    ..These results, therefore, support the hypothesis that the milk of otariids, unlike that of phocids, contains no free reducing saccharides...
  18. doi request reprint Chemical characterization of oligosaccharides in chimpanzee, bonobo, gorilla, orangutan, and siamang milk or colostrum
    Tadasu Urashima
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan
    Glycobiology 19:499-508. 2009
    ..Since these analyses are based on a limited number of individuals, further research on additional samples of great and lesser ape milk is needed to confirm phylogenetic patterns...
  19. ncbi request reprint Chemical characterization of the oligosaccharides in beluga (Delphinapterus leucas) and Minke whale (Balaenoptera acutorostrata) milk
    Tadasu Urashima
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 132:611-24. 2002
    ..Therefore, lactose may not be a source of energy for suckling beluga whales...
  20. ncbi request reprint Oligosaccharides of milk and colostrum in non-human mammals
    T Urashima
    Department of Bio Resource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Hokkaido, 080 8555, Japan
    Glycoconj J 18:357-71. 2001
    ..g. wallaby). The gastrointestinal digestion and absorption and the possible biological functions of these oligosaccharides are also discussed...
  21. ncbi request reprint Chemical characterisation of the oligosaccharides in a sample of milk of a white-nosed coati, Nasua narica (Procyonidae: Carnivora)
    T Urashima
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Comp Biochem Physiol A Mol Integr Physiol 123:187-93. 1999
    ..Free lactose constituted only about one-third of the total free milk saccharides. The results are discussed in terms of comparisons with the milk sugars of bears and other species...
  22. ncbi request reprint An NMR study of the lactonization of alpha-N-acetylneuraminyl-(2 --> 3)-lactose
    T Nakamura
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Carbohydr Res 329:471-6. 2000
    ..The NMR data led to the tentative conclusion that the reaction also yielded small amounts of lactose, and alpha-Neu5Ac-(2 --> 3)-beta-D-Galp-(1 --> 4)-D-Glc-(1c --> 4b)-lactone which was stable in aqueous solution...
  23. ncbi request reprint Variation of major neutral oligosaccharides levels in human colostrum
    S Asakuma
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Eur J Clin Nutr 62:488-94. 2008
    ..The aim of this present study was to determine the concentration of each of the major neutral oligosaccharide for three consecutive days from the start of lactation...
  24. ncbi request reprint Concentrations of sialyloligosaccharides in bovine colostrum and milk during the prepartum and early lactation
    T Nakamura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, 080 8555, Japan
    J Dairy Sci 86:1315-20. 2003
    ..Bovine colostrum, especially that collected immediately after parturition, may be suitable as a source of 3'SL and other sialyloligosaccharides for use as additives by the food or pharmaceutical industries...
  25. ncbi request reprint Occurrence of an unusual phosphorylated N-acetyllactosamine in horse colostrum
    T Nakamura
    Department of Bioresource, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Biochim Biophys Acta 1525:13-8. 2001
    ..The structures of these saccharides were established by NMR spectroscopy and MALDI-TOF mass spectrometry...
  26. ncbi request reprint Occurrence of a unique sialyl tetrasaccharide in colostrum of a bottlenose dolphin (Tursiops truncatus)
    Yusuke Uemura
    Department of Bioresource Chemistry, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Biochim Biophys Acta 1725:290-7. 2005
    ....
  27. doi request reprint Short communication: evidence for the presence of a putative odorant-binding protein in bovine colostrum
    K Fukuda
    Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Dairy Sci 92:4992-6. 2009
    ..Its biological function is unclear, but pheromone transport could be considered. This is the first report of a putative odorant-binding protein in bovine colostrum...
  28. ncbi request reprint Purification and characterization of a novel exo-beta-1,3-1,6-glucanase from the fruiting body of the edible mushroom Enoki (Flammulina velutipes)
    Kenji Fukuda
    Meat and Milk Hygiene, Graduate School of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Biosci Biotechnol Biochem 72:3107-13. 2008
    ..FvBGL1 can be assumed to degrade F. velutipes cell-wall beta-1,3-glucan, but most probably acts more efficiently in concert with other endogenous beta-glucan degrading enzymes...
  29. ncbi request reprint Composition and oligosaccharides of a milk sample of the giant panda, Ailuropoda melanoleuca
    Tadashi Nakamura
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, 080 8555, Japan
    Comp Biochem Physiol B Biochem Mol Biol 135:439-48. 2003
    ....
  30. ncbi request reprint Bovine lactoferrin stimulates anchorage-independent cell growth via membrane-associated chondroitin sulfate and heparan sulfate proteoglycans in PC12 cells
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    J Pharmacol Sci 104:366-73. 2007
    ..These results suggest that bLf binds to the membrane of PC12 cells via membrane-associated proteoglycans and leads to anchorage-independent growth...
  31. doi request reprint A naturally occurring αs1 -casein-derived peptide in bovine milk inhibits apoptosis of granulosa cells induced by serum-free conditions
    T Shimizu
    Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, 2 11 Inada cho, Obihiro, 080 8555, Hokkaido, Japan
    J Pept Sci 20:229-34. 2014
    ..Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd. ..
  32. ncbi request reprint Determination of each neutral oligosaccharide in the milk of Japanese women during the course of lactation
    Wataru Sumiyoshi
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Hokkaido, 080 8555, Japan
    Br J Nutr 89:61-9. 2003
    ..These differences may be caused by different assay methodology, although racial differences cannot be ruled out...
  33. ncbi request reprint Sialyl oligosaccharides of human colostrum: changes in concentration during the first three days of lactation
    Sadaki Asakuma
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Japan
    Biosci Biotechnol Biochem 71:1447-51. 2007
    ..These results are consistent with the view that during the first 3 d of lactation, the concentration of sialyl oligosaccharides in human colostrum change in accordance with the physiological demands of newborn infants...
  34. ncbi request reprint Are there two forms of beta 2-N-acetylglucosaminyltransferase I in rat testicular and epididymal fluids?
    Hirofumi Nozaki
    Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Inanda, Obihiro, Hokkaido 080 8555, Japan
    Biochim Biophys Acta 1649:140-5. 2003
    ..These data suggest that two forms of GnT I exist in the testicular and epididymal fluids...
  35. ncbi request reprint Determination of sialyl and neutral oligosaccharide levels in transition and mature milks of Samoan women, using anthranilic derivatization followed by reverse phase high performance liquid chromatography
    Fiame Leo
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    Biosci Biotechnol Biochem 74:298-303. 2010
    ..The differences in neutral oligosaccharides might have a genetic origin...
  36. ncbi request reprint Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside
    Michiko Sugai
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    J Oleo Sci 58:91-6. 2009
    ....
  37. ncbi request reprint Selection of lactic yeast producing glucosylceramide from cheese whey
    M Sugai
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Bioresour Technol 98:3643-6. 2007
    ..Sequence analysis of ribosomal DNA intergenic spacer two regions revealed that strains M-11 and M-16 were diverged from a type strain of K. lactis var. lactis in the same species...
  38. doi request reprint Improved determination of milk oligosaccharides using a single derivatization with anthranilic acid and separation by reversed-phase high-performance liquid chromatography
    Fiame Leo
    Graduate School of Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    J Chromatogr A 1216:1520-3. 2009
    ..The recoveries were in the range of 80-100%. This method was successfully applied to the separation and determination of representative neutral oligosaccharide contents in Samoa women milk...
  39. ncbi request reprint N-acetylglucosaminyltransferase I activity of bovine oviduct epithelial cells: stimulation by luteinizing hormone, vascular endothelial growth factor and tumor necrosis factor alpha
    Hirofumi Nozaki
    Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Reprod Dev 51:229-34. 2005
    ....
  40. ncbi request reprint Capillary affinity electrophoresis using lectins for the analysis of milk oligosaccharide structure and its application to bovine colostrum oligosaccharides
    Kazuki Nakajima
    Faculty of Pharmaceutical Sciences, Kinki University, Kowakae 3 4 1, Higashiosaka shi, Osaka 577 8502, Japan
    Anal Biochem 348:105-14. 2006
    ..In addition, using the library, we show that a combination of the lectins can characterize the neutral oligosaccharides derived from bovine colostrum...
  41. ncbi request reprint Specific recognition of Leishmania major poly-beta-galactosyl epitopes by galectin-9: possible implication of galectin-9 in interaction between L. major and host cells
    Isabelle Pelletier
    Glycobiology Laboratory, Research Centre for Infectious Diseases, Laval University Medical Centre, Centre Hospitalier Universitaire de Quebec, Quebec G1V 4G2, Canada
    J Biol Chem 278:22223-30. 2003
    ..major and macrophages, suggesting distinctive roles for the galectins in the L. major-specific development of leishmaniasis in the host...
  42. ncbi request reprint Oligosaccharide specificity of galectins: a search by frontal affinity chromatography
    Jun Hirabayashi
    Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Teikyo University, Sagamiko, Kanagawa 199 0195, Japan
    Biochim Biophys Acta 1572:232-54. 2002
    ..On these bases, they are considered to exert specialized functions in diverse biological phenomena, which may include formation of local cell-surface microdomains (raft) by sorting glycoconjugate members for each cell type...