Ikumi Shiga

Summary

Affiliation: Obihiro University of Agriculture and Veterinary Medicine
Country: Japan

Publications

  1. ncbi request reprint Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii
    Fumiaki Ihara
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro Hokkaido 080 8555, Japan
    Parasit Vectors 7:248. 2014
  2. ncbi request reprint Overproduction of Toxoplasma gondii cyclophilin-18 regulates host cell migration and enhances parasite dissemination in a CCR5-independent manner
    Hany M Ibrahim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    BMC Microbiol 14:76. 2014
  3. doi request reprint α2-3 Sialic acid glycoconjugate loss and its effect on infection with Toxoplasma parasites
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan Electronic address
    Exp Parasitol 135:479-85. 2013
  4. pmc Enzyme-linked immunosorbent assays based on Neospora caninum dense granule protein 7 and profilin for estimating the stage of neosporosis
    Jun Hiasa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    Clin Vaccine Immunol 19:411-7. 2012
  5. ncbi request reprint Toxoplasma gondii infection induces apoptosis in noninfected macrophages: role of nitric oxide and other soluble factors
    Y Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    Parasite Immunol 29:375-85. 2007
  6. doi request reprint Effects of a transferring antibody against Neospora caninum infection in a murine model
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 160:60-5. 2009
  7. ncbi request reprint Roles of CD122+ cells in resistance against Neospora caninum infection in a murine model
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    J Vet Med Sci 72:1275-82. 2010
  8. ncbi request reprint Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    J Vet Med Sci 73:633-9. 2011

Collaborators

  • Xuenan Xuan
  • Hidefumi Furuoka
  • H Suzuki
  • Hisashi Inokuma
  • Yoshifumi Nishikawa
  • Hany M Ibrahim
  • Maki Nishimura
  • Jun Hiasa
  • Fumiaki Ihara
  • Kyohko Kameyama
  • Houshuang Zhang
  • Y Nishikawa
  • Sachi Tanaka
  • Walaa Awadin
  • Ayako Ogiso
  • Yuzuru Ikehara
  • Kazuhito Itamoto
  • Hideyuki Nagasawa
  • Kyoko Yamada
  • Guohong Zhang
  • Penglong Huang
  • O Vielemeyer
  • O Kawase
  • H Nagasawa
  • K A Joiner

Detail Information

Publications8

  1. ncbi request reprint Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii
    Fumiaki Ihara
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro Hokkaido 080 8555, Japan
    Parasit Vectors 7:248. 2014
    ..However, the extent to which host nutrients contribute to stage conversion in T. gondii is unknown. In this study, we examined the impact of host cholesterol levels on stage conversion in this parasite...
  2. ncbi request reprint Overproduction of Toxoplasma gondii cyclophilin-18 regulates host cell migration and enhances parasite dissemination in a CCR5-independent manner
    Hany M Ibrahim
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    BMC Microbiol 14:76. 2014
    ..We examined the functional role of T. gondii cyclophilin 18 (TgCyp18) in host cell recruitment using recombinant parasites transfected with TgCyp18...
  3. doi request reprint α2-3 Sialic acid glycoconjugate loss and its effect on infection with Toxoplasma parasites
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan Electronic address
    Exp Parasitol 135:479-85. 2013
    ..gondii. ..
  4. pmc Enzyme-linked immunosorbent assays based on Neospora caninum dense granule protein 7 and profilin for estimating the stage of neosporosis
    Jun Hiasa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    Clin Vaccine Immunol 19:411-7. 2012
    ..In conclusion, antibodies against NcGRA7 and NcPF may have potential as suitable indicators for estimating the pathological status of neosporosis...
  5. ncbi request reprint Toxoplasma gondii infection induces apoptosis in noninfected macrophages: role of nitric oxide and other soluble factors
    Y Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    Parasite Immunol 29:375-85. 2007
    ..Altogether, our findings indicate that apoptosis in bystander host cells is due to the secretion of NO and other soluble factors released by parasite-infected cells...
  6. doi request reprint Effects of a transferring antibody against Neospora caninum infection in a murine model
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    Vet Parasitol 160:60-5. 2009
    ..There was no significant difference on the parasite burden in dams and the survival rates of their offspring. Here, we have shown that N. caninum-specific transferring antibody does not control parasite infection in mice...
  7. ncbi request reprint Roles of CD122+ cells in resistance against Neospora caninum infection in a murine model
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    J Vet Med Sci 72:1275-82. 2010
    ..caninum infection. These results indicate that CD122+ cells (probably NKT cells) play a crucial role in host defense by activating CD4+ T cells against N. caninum infection...
  8. ncbi request reprint Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages
    Yoshifumi Nishikawa
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido 080 8555, Japan
    J Vet Med Sci 73:633-9. 2011
    ..The present study demonstrates that lovastatin, compactin and squalestatin have anti-Toxoplasma activities and that the host cholesterol synthesis may contribute to parasite growth in macrophages...