Y Omata

Summary

Affiliation: Obihiro University of Agriculture and Veterinary Medicine
Country: Japan

Publications

  1. ncbi request reprint Development of Neospora caninum cultured with human serum in vitro and in vivo
    Y Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    J Parasitol 91:222-5. 2005
  2. ncbi request reprint Footpad reaction induced by Neospora caninum tachyzoite extract in infected BALB/c mice
    Y Omata
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    Vet Parasitol 139:102-8. 2006
  3. ncbi request reprint Vertical transmission of Neospora caninum in BALB/c mice in both acute and chronic infection
    Y Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    Vet Parasitol 121:323-8. 2004
  4. ncbi request reprint Toxoplasma gondii does not persist in goldfish (Carassius auratus)
    Y Omata
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Japan
    J Parasitol 91:1496-9. 2005
  5. ncbi request reprint Antibodies against Toxoplasma gondii in the Pacific bottlenose dolphin (Tursiops aduncus) from the Solomon Islands
    Yoshitaka Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro 080 8555, Japan
    J Parasitol 91:965-7. 2005
  6. ncbi request reprint Prevalence of Toxoplasma gondii and Neospora caninum in sika deer from eastern Hokkaido, Japan
    Yoshitaka Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Wildl Dis 41:454-8. 2005
  7. ncbi request reprint Identification of carbohydrates on Eimeria stiedai sporozoites and their role in invasion of cultured cells in vitro
    Y Omata
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Tokai J Exp Clin Med 23:365-71. 1998
  8. ncbi request reprint Specific IgA antibody response to coproantigens of Cryptosporidium parvum in serum and saliva of calves after experimental infection
    A Toyoguchi
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, 080-8555, Obihiro, Japan
    Vet Parasitol 96:213-20. 2001
  9. ncbi request reprint Eimeria stiedai merozoite 49-kDa soluble antigen induces protection against infection
    S Hanada
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    J Parasitol 89:613-7. 2003
  10. ncbi request reprint A 14-3-3 protein homologue is expressed in feline enteroepithelial-stages of Toxoplasma gondii
    T Koyama
    Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan
    Vet Parasitol 96:65-74. 2001

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Development of Neospora caninum cultured with human serum in vitro and in vivo
    Y Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    J Parasitol 91:222-5. 2005
    ..Scid mice administered FBS survived until the end of the experiment. These results suggest that adult human serum may have no inhibitory effect on the development of N. caninum in vitro and in vivo...
  2. ncbi request reprint Footpad reaction induced by Neospora caninum tachyzoite extract in infected BALB/c mice
    Y Omata
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    Vet Parasitol 139:102-8. 2006
    ..These results indicate that mice infected with N. caninum produce a DTH reaction, which is a good indicator of the development of type 1 immune responses...
  3. ncbi request reprint Vertical transmission of Neospora caninum in BALB/c mice in both acute and chronic infection
    Y Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    Vet Parasitol 121:323-8. 2004
    ..Interestingly, congenital transmission was observed in 86% of the neonates from Group 3. These results suggest that chronically-infected BALB/c mice efficiently transmit N. caninum infection to their offspring...
  4. ncbi request reprint Toxoplasma gondii does not persist in goldfish (Carassius auratus)
    Y Omata
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Japan
    J Parasitol 91:1496-9. 2005
    ..When inoculated goldfish were kept at 37 C, live tachyzoites were seen at the inoculation site on day 3, but not on day 7. These results suggest that T. gondii does not persist in fish...
  5. ncbi request reprint Antibodies against Toxoplasma gondii in the Pacific bottlenose dolphin (Tursiops aduncus) from the Solomon Islands
    Yoshitaka Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro 080 8555, Japan
    J Parasitol 91:965-7. 2005
    ..The specific binding of IgG antibodies to T. gondii antigens observed for serum samples producing higher titers suggests that Pacific bottlenose dolphins from the Solomon islands are exposed to T. gondii...
  6. ncbi request reprint Prevalence of Toxoplasma gondii and Neospora caninum in sika deer from eastern Hokkaido, Japan
    Yoshitaka Omata
    Laboratory of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Wildl Dis 41:454-8. 2005
    ..Further examination of multiple tissues by PCR and serologic surveys will be necessary to confirm this...
  7. ncbi request reprint Identification of carbohydrates on Eimeria stiedai sporozoites and their role in invasion of cultured cells in vitro
    Y Omata
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Tokai J Exp Clin Med 23:365-71. 1998
    ..These results indicate that L-fucose residues on E. stiedai sporozoites and L-fucose binding sites on host cells both are associated with recognition and/or invasion process...
  8. ncbi request reprint Specific IgA antibody response to coproantigens of Cryptosporidium parvum in serum and saliva of calves after experimental infection
    A Toyoguchi
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, 080-8555, Obihiro, Japan
    Vet Parasitol 96:213-20. 2001
    ..These results suggest that this coproantigen may be released from C. parvum sporozoites and may induce IgA antibody production in the mucosal immune system of infected calves...
  9. ncbi request reprint Eimeria stiedai merozoite 49-kDa soluble antigen induces protection against infection
    S Hanada
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    J Parasitol 89:613-7. 2003
    ..These results suggest that the 49-kDa soluble protein antigen detected in the bile of the infected rabbits was a merozoite-specific antigen, and the immune reaction to the antigen may induce protective effects against the infection...
  10. ncbi request reprint A 14-3-3 protein homologue is expressed in feline enteroepithelial-stages of Toxoplasma gondii
    T Koyama
    Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan
    Vet Parasitol 96:65-74. 2001
    ..These findings suggest that T. gondii parasites produce a protein showing partial homology with members of the 14-3-3 protein family and this protein is expressed in feline enteroepithelial-stages parasites...
  11. ncbi request reprint Identification and the role of soluble antigens detected in bile from Eimeria stiedai-infected rabbits
    Y Omata
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Parasitol 87:287-91. 2001
    ..These results indicate that soluble antigens are present in the bile of rabbits in the acute phase of infection, and these may be produced and released by merozoites during the host cell invasion process...
  12. ncbi request reprint Relationship between type 1/type 2 immune responses and occurrence of vertical transmission in BALB/c mice infected with Neospora caninum
    R Kano
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro 080 8555, Japan
    Vet Parasitol 129:159-64. 2005
    ....
  13. ncbi request reprint Naturally-occurring Neospora caninum infection in an adult sheep and her twin fetuses
    Y Kobayashi
    Department of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Parasitol 87:434-6. 2001
    ..A N. caninum-specific DNA fragment was detected in a brain homogenate of the ewe by the polymerase chain reaction method. This is the first report of N. caninum infection in twin ovine fetuses and in an adult sheep...
  14. ncbi request reprint Increase of Th1 type cytokine mRNA expression in peripheral blood lymphocytes of calves experimentally infected with Cryptosporidium parvum
    K Takeda
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, 080 8555, Japan
    Vet Parasitol 113:327-31. 2003
    ..Our observations suggest that systemic Th1 type immune responses are induced in calves infected with C. parvum and may be available for evaluation of the control of the infection...
  15. ncbi request reprint Trail antigen in Eimeria stiedai sporozoites associated with a thrombospondin-related motif and the entry of cultured cells
    H Watanabe
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro 080-8555, Japan
    Vet Parasitol 99:287-95. 2001
    ..tenella microneme protein Etp 100. This protein may play an important functional role in the process of penetration of host cells...
  16. ncbi request reprint Reduction of the infectivity of Toxoplasma gondii and Eimeria stiedai sporozoites by treatment with bovine lactoferricin
    Y Omata
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Vet Med Sci 63:187-90. 2001
    ..These results indicate that lactoferricin is effective to reduce the infectivity of sporozoites of Toxoplasma gondii and Eimeria stiedai...
  17. ncbi request reprint Isolation of Neospora caninum from the brain of a pregnant sheep
    T Koyama
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Parasitol 87:1486-8. 2001
    ..caninum antibodies and by detecting N. caninum-specific DNA by polymerase chain reaction...
  18. ncbi request reprint Relationship between liver disorders and protection against Eimeria stiedai infection in rabbits immunized with soluble antigens from the bile of infected rabbits
    S Hanada
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro 080 8555, Japan
    Vet Parasitol 111:261-6. 2003
    ..These results suggest that the soluble antigens stimulate local immune reactions, for example around the biliary ducts, resulting in elimination of the parasite's development...
  19. ncbi request reprint Modified protection against Toxoplasma gondii lethal infection and brain cyst formation by vaccination with SAG2 and SRS1
    M Mishima
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    J Vet Med Sci 63:433-8. 2001
    ..The protection modified by boost in specific antibody is suggestive of the immunogenic potential of SAG2, SRS1 and possibly P54 against T. gondii infection...
  20. doi request reprint Serological survey of Toxoplasma gondii in wild waterfowl in Chukotka, Kamchatka, Russia and Hokkaido, Japan
    Takehiro Murao
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan
    J Parasitol 94:830-3. 2008
    ..No specific bands were noted in samples for which antibody activity was not detected. These results suggest that wild waterfowl inhabiting Hokkaido, Chukotka, and Kamchatka may be exposed to T. gondii...
  21. ncbi request reprint Investigation for presence of Neospora caninum, Toxoplasma gondii and Brucella-species infection in killer whales (Orcinus orca) mass-stranded on the coast of Shiretoko, Hokkaido, Japan
    Yoshitaka Omata
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan
    J Vet Med Sci 68:523-6. 2006
    ..5) showed antibody binding to N. caninum antigens. In the PCR assay, none of the samples was positive. Further study is necessary to examine the prevalence of the pathogens in marine mammals inhabiting this area...
  22. pmc Roles of CD4(+) T cells and gamma interferon in protective immunity against Babesia microti infection in mice
    I Igarashi
    The Research Center for Protozoan Molecular Immunology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Maebashi, The University of Tokyo, Tokyo, Japan
    Infect Immun 67:4143-8. 1999
    ..These results suggest essential requirements for CD4(+) T cells and IFN-gamma in protective immunity against challenge infection with B. microti...
  23. doi request reprint Infection of different strains of mice with Lawsonia intracellularis derived from rabbit or porcine proliferative enteropathy
    K Murakata
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    J Comp Pathol 139:8-15. 2008
    ..intracellularis infection. Moreover, the susceptibility of BALB/cA mice to RLI but not to PLI suggests that there are significant biological differences between L. intracellularis isolates from rabbit PE and porcine PE...
  24. ncbi request reprint Acute restraint stress enhances calcium mobilization and proliferative response in splenic lymphocytes from mice
    Eiki Satoh
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, 080 8555, Japan
    Stress 9:223-30. 2006
    ..These results suggest that acute restraint stress enhances Con A-stimulated T-cell proliferation by increasing [Ca2+ ]i via stimulation of Ca2+ entry...
  25. ncbi request reprint Toxoplasma gondii: DNA vaccination with genes encoding antigens MIC2, M2AP, AMA1 and BAG1 and evaluation of their immunogenic potential
    George Dautu
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Exp Parasitol 116:273-82. 2007
    ..Therefore, the AMA1 gene appears to generate a strong specific immune response and also provides effective protection against toxoplasmosis more than the MIC2, M2AP and BAG1 genes...
  26. ncbi request reprint Changes in salivary cortisol concentrations during a 24-hour period in dogs
    T Koyama
    Department of Veterinary Physiology, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro, Hokkaido, Japan
    Horm Metab Res 35:355-7. 2003
    ..No circadian rhythm was detected for salivary cortisol, and the differences among salivary cortisol concentrations measured every hour were not demonstrated during a 24-hour period in dogs...
  27. ncbi request reprint Toxoplasma gondii: detection of MIC10 antigen in sera of experimentally infected mice
    George Dautu
    National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, 080 8555 Japan
    Exp Parasitol 118:362-71. 2008
    ..In sera of PLK-infected mice, MIC10 was predominantly observed between late acute and early chronic phase. Our data show that the kinetics of circulating MIC10 differs depending on the strain and route of infection...
  28. ncbi request reprint Expression of mRNA of chemokine receptor CXCR4 in feline mammary adenocarcinoma
    S Tanabe
    Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, 2 11 Inada, Obihiro, Hokkaido 080 8555, Japan
    Vet Rec 151:729-33. 2002
    ..005), but there was no significant relationship between its expression and the one-year survival of the cats...
  29. ncbi request reprint A serological survey of Brucella spp. in free-ranging wild boar (Sus scrofa leucomystax) in Shikoku, Japan
    Masahisa Watarai
    Department of Applied Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    J Vet Med Sci 68:1139-41. 2006
    ..In 9 of the 115 samples (7.8%) antibodies to Brucella spp. were detected by TAT and ELISA. These results suggest that wild boar in Shikoku may be exposed to Brucella spp. or other cross-reactive pathogen infection...
  30. ncbi request reprint C57BL/6 mice infected with Neospora caninum during administration of progesterone show bias toward type 2 immune response
    Rika Kano
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Vet Med Sci 69:1095-7. 2007
    ..These results suggest that progesterone may alter the balance of cytokine production, and that the bias toward type 2 immune response may remain for a certain period after the infection...
  31. ncbi request reprint Antibodies to Brucella spp. in Pacific bottlenose dolphins from the Solomon Islands
    Masato Tachibana
    Department of Applied Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Wildl Dis 42:412-4. 2006
    ..antibodies were detected by TAT and ELISA in 31 and 40 of 58 samples, respectively. These results suggest that Pacific bottlenose dolphins from the Solomon Islands are infected with Brucella spp. or a Brucella-like organism...
  32. ncbi request reprint Possibility of Neospora caninum infection by venereal transmission in CB-17 scid mice
    Tsuneyuki Masuda
    Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Inada cho, Obihiro 080 8555, Japan
    Vet Parasitol 149:130-3. 2007
    ..These results indicate that the tachyzoites were present in the genital organs of the immunodeficient mice from day 7 p.i. and suggest that transmission may occur through mating with male mice...
  33. ncbi request reprint Enzyme-linked immunosorbent assay to detect Lawsonia intracellularis in rabbits with proliferative enteropathy
    Masahisa Watarai
    Department of Applied Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    J Vet Med Sci 66:735-7. 2004
    ..intracellularis by enzyme-linked immunosorbent assay. These results suggest that ELISA used synthetic peptides in LsaA and anti-LsaA serum might be useful to diagnose for proliferative enteropathy...
  34. doi request reprint A survey of abortifacient infectious agents in livestock in Luzon, the Philippines, with emphasis on the situation in a cattle herd with abortion problems
    Satoru Konnai
    Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060 0818, Japan
    Acta Trop 105:269-73. 2008
    ..BVDV was not detected in these herds. The findings of this exploratory study indicate a relationship between infection and bovine abortion and that a lager study is required to statistically confirm this relationship...