Toshiaki Ishii

Summary

Affiliation: Obihiro University of Agriculture and Veterinary Medicine
Country: Japan

Publications

  1. ncbi request reprint Administration of xenobiotics with anti-estrogenic effects results in mRNA induction of adult male-specific cytochrome P450 isozymes in the livers of adult female rats
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Pharmacol Sci 101:250-5. 2006
  2. ncbi request reprint Comparison of growth and exploratory behavior in mice fed an exclusively milk formula diet and mice fed a food-pellet diet post weaning
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Life Sci 78:174-9. 2005
  3. ncbi request reprint The mesencephalic trigeminal sensory nucleus is involved in the control of feeding and exploratory behavior in mice
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1048:80-6. 2005
  4. ncbi request reprint The mesencephalic trigeminal sensory nucleus is involved in acquisition of active exploratory behavior induced by changing from a diet of exclusively milk formula to food pellets in mice
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1111:153-61. 2006
  5. ncbi request reprint Chronic intracerebroventricular administration of anti-neuropeptide Y antibody stimulates starvation-induced feeding via compensatory responses in the hypothalamus
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido 080 8555, Japan
    Brain Res 1144:91-100. 2007
  6. ncbi request reprint Inactivation of integrin-linked kinase induces aberrant tau phosphorylation via sustained activation of glycogen synthase kinase 3beta in N1E-115 neuroblastoma cells
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido 080 8555, Japan
    J Biol Chem 278:26970-5. 2003
  7. ncbi request reprint Bovine lactoferrin stimulates anchorage-independent cell growth via membrane-associated chondroitin sulfate and heparan sulfate proteoglycans in PC12 cells
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    J Pharmacol Sci 104:366-73. 2007
  8. doi request reprint Integrin-linked kinase is involved in lactoferrin-induced anchorage-independent cell growth and survival in PC12 cells
    Toshiaki Ishii
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Life Sci 84:530-6. 2009
  9. doi request reprint Bilateral lesions of the mesencephalic trigeminal sensory nucleus stimulate hippocampal neurogenesis but lead to severe deficits in spatial memory resetting
    Toshiaki Ishii
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1342:74-84. 2010
  10. ncbi request reprint Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells
    T Ishii
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Biol Chem 276:42994-3003. 2001

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Administration of xenobiotics with anti-estrogenic effects results in mRNA induction of adult male-specific cytochrome P450 isozymes in the livers of adult female rats
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Japan
    J Pharmacol Sci 101:250-5. 2006
    ..Thus, induction of the adult male-specific CYP isozymes in adult female roof rats captured in Osaka might be caused by consumption of xenobiotics with anti-estrogenic effects...
  2. ncbi request reprint Comparison of growth and exploratory behavior in mice fed an exclusively milk formula diet and mice fed a food-pellet diet post weaning
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Life Sci 78:174-9. 2005
    ..These results suggest that the growth stunt caused by an exclusively milk formula diet retards the acquisition of active exploratory behavior without affecting the emotional state of mice...
  3. ncbi request reprint The mesencephalic trigeminal sensory nucleus is involved in the control of feeding and exploratory behavior in mice
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1048:80-6. 2005
    ..These results suggest that the Me5 is involved in the control of feeding and exploratory behavior through its ascending neuronal pathways in mice without modulating the emotional state...
  4. ncbi request reprint The mesencephalic trigeminal sensory nucleus is involved in acquisition of active exploratory behavior induced by changing from a diet of exclusively milk formula to food pellets in mice
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1111:153-61. 2006
    ..These results suggest that the Me5 is activated by signals associated with mastication-induced proprioception and contributes to the acquisition of active exploratory behavior...
  5. ncbi request reprint Chronic intracerebroventricular administration of anti-neuropeptide Y antibody stimulates starvation-induced feeding via compensatory responses in the hypothalamus
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido 080 8555, Japan
    Brain Res 1144:91-100. 2007
    ..On the other hand, in mice that have acquired this compensation, fast-induced food intake further increases even after the energy deficit is corrected because of the dominant orexigenic signal...
  6. ncbi request reprint Inactivation of integrin-linked kinase induces aberrant tau phosphorylation via sustained activation of glycogen synthase kinase 3beta in N1E-115 neuroblastoma cells
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido 080 8555, Japan
    J Biol Chem 278:26970-5. 2003
    ..ILK directly phosphorylates GSK-3beta and inhibits its activity. Therefore, endogenous ILK protects against GSK-3beta-induced aberrant tau phosphorylation via inhibition of GSK-3beta activity in N1E-115 cells...
  7. ncbi request reprint Bovine lactoferrin stimulates anchorage-independent cell growth via membrane-associated chondroitin sulfate and heparan sulfate proteoglycans in PC12 cells
    Toshiaki Ishii
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan
    J Pharmacol Sci 104:366-73. 2007
    ..These results suggest that bLf binds to the membrane of PC12 cells via membrane-associated proteoglycans and leads to anchorage-independent growth...
  8. doi request reprint Integrin-linked kinase is involved in lactoferrin-induced anchorage-independent cell growth and survival in PC12 cells
    Toshiaki Ishii
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Life Sci 84:530-6. 2009
    ..Bovine lactoferrin (bLf) causes anchorage-independent cell growth in PC12 cells. The present study investigated the mechanisms involved in bLf-induced anchorage-independent cell growth and survival in PC12 cells...
  9. doi request reprint Bilateral lesions of the mesencephalic trigeminal sensory nucleus stimulate hippocampal neurogenesis but lead to severe deficits in spatial memory resetting
    Toshiaki Ishii
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Brain Res 1342:74-84. 2010
    ..These results suggest that Me5 contributes to spatial memory resetting by controlling the rate of hippocampal neurogenesis through an ascending neuronal pathway to the hippocampus...
  10. ncbi request reprint Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells
    T Ishii
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Biol Chem 276:42994-3003. 2001
    ..Thus, activation of p38 MAP kinase is involved in ILK-mediated signal transduction leading to integrin-dependent neurite outgrowth in N1E-115 cells...
  11. doi request reprint Post-weaning mice fed exclusively milk have deficits in induction of long-term depression in the CA1 hippocampal region and spatial learning and memory
    Hideaki Nishie
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    Neurosci Res 73:292-301. 2012
    ....
  12. ncbi request reprint Calcineurin contributes to the enhancing effect of adenosine on nerve growth factor-induced neurite outgrowth via the decreased duration of p38 mitogen-activated protein kinase phosphorylation
    Yoshikage Muroi
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    J Pharmacol Sci 95:124-31. 2004
    ..These results suggest that adenosine decreases the duration of p38 MAP kinase via calcineurin activation, which contributes to the enhancement of NGF-induced neurite outgrowth...
  13. doi request reprint Changes in the bovine whey proteome during the early lactation period
    Akitsugu Senda
    Departments of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan
    Anim Sci J 82:698-706. 2011
    ..The characteristics of whey proteins in transition imply that enhancement of innate immunity becomes more important than protection of the neonate against pathogens via passive immunity after 48 h postpartum...
  14. doi request reprint Improved calcium utilization at motor nerve terminals exposed to botulinum neurotoxin in mice
    Ryu Fujikawa
    Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, 1 1 Yanagido, Gifu, 501 1193 Japan
    J Physiol Sci 58:419-24. 2008
    ..The improved efficiency of evoked quantum release probably involves remodeling of voltage-gated Ca2+ channels, intracellular Ca2+ store sites, or transmitter-releasing apparatuses...
  15. ncbi request reprint A competitive effect of androgen signaling on male mouse attraction to volatile female mouse odors
    Yoshikage Muroi
    Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Physiol Behav 87:199-205. 2006
    ..These results suggest that neither androgen nor estrogen is sufficient for reproducing male attraction to volatile female mouse odors, and that androgen signaling has a competitive effect against the attraction...
  16. ncbi request reprint Volatile female odors activate the accessory olfactory system of male mice without physical contact
    Y Muroi
    Department of Pathogenetic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
    Neuroscience 141:551-8. 2006
    ..These results suggest that male mice discriminated whether or not female mice were ovariectomized, by volatile odors via the accessory olfactory system, and that the female-specific volatile odors are involved in reproduction...
  17. ncbi request reprint The mechanism of maitotoxin-induced elevation of the cytosolic free calcium level in rat cerebrocortical synaptosomes
    E Satoh
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Japan
    Jpn J Pharmacol 85:98-100. 2001
    ....
  18. doi request reprint Umami taste receptor functions as an amino acid sensor via Gαs subunit in N1E-115 neuroblastoma cells
    Yoshikage Muroi
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido, 080 8555, Japan
    J Cell Biochem 113:1654-62. 2012
    ..We concluded that Tas1r1 + 3 functions as an amino acid sensor and activates the intracellular signaling pathway through the Gαs subunit in N1E-115 cells...
  19. ncbi request reprint Palytoxin-induced increase in cytosolic-free Ca(2+) in mouse spleen cells
    Eiki Satoh
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080 8555, Japan
    Eur J Pharmacol 465:9-13. 2003
    ..These results suggest that palytoxin increases [Ca(2+)](i) in mouse spleen cells by stimulating Ca(2+) entry through an SKF-96365-, Ni(2+)-sensitive pathway...
  20. ncbi request reprint A mechanism of the thearubigin fraction of black tea (Camellia sinensis) extract protecting against the effect of tetanus toxin
    Eiki Satoh
    Department of Pathobiological Science, Obihiro University of Agriculture and Veterinary Medicine, 11, West 2, Inada, Obihiro 080 8555, Japan
    J Toxicol Sci 27:441-7. 2002
    ..These findings indicate that thearubigin fraction protects against the action of tetanus toxin by binding with the toxin...
  21. ncbi request reprint The mechanism underlying the protective effect of the thearubigin fraction of black tea (Camellia sinensis) extract against the neuromuscular blocking action of botulinum neurotoxins
    Eiki Satoh
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Obihiro 080 8555, Japan
    Pharmacol Toxicol 90:199-202. 2002
    ..These findings indicate that thearubigin fraction protects against the neuromuscular blocking action of botulinum neurotoxin types A, B, and E by binding with the toxins...
  22. ncbi request reprint [Isolation and determination of an antidote for botulinum neurotoxin from black tea extract]
    Shin ichi Sawamura
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Japan
    Nihon Yakurigaku Zasshi 120:116P-118P. 2002
    ..The structural elucidation of the compounds by means of NMR spectrascopy revealed, kaempfenol-3-O-[glc-(6-1)-rha-(3-1)-glc];keampfetrin, kaempferol-3-O-[glc-(6-1)-rha];nicotiflorin and quercetin glycoside...
  23. doi request reprint Short communication: evidence for the presence of a putative odorant-binding protein in bovine colostrum
    K Fukuda
    Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080 8555, Japan
    J Dairy Sci 92:4992-6. 2009
    ..Its biological function is unclear, but pheromone transport could be considered. This is the first report of a putative odorant-binding protein in bovine colostrum...
  24. ncbi request reprint Black tea extract, thearubigin fraction, counteracts the effect of tetanus toxin in mice
    E Satoh
    Department of Pharmacology, University of Obihiro School of Veterinary Medicine, Obihiro 080-8555, Japan
    Exp Biol Med (Maywood) 226:577-80. 2001
    ..These results imply that thearubigin fraction counteracts the effect of tetanus toxin by binding with toxin, and also suggest that this fraction may be able to apply for prophylaxis of tetanus...
  25. ncbi request reprint Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase
    Katsuaki Ito
    Department of Veterinary Pharmacology, Faculty of Agriculture, Miyazaki University, 889 2192, Miyazaki, Japan
    FEBS Lett 543:108-12. 2003
    ..Ouabain inhibited the effect of PTX in NNN or NCN cells but not in ouabain-resistant cells. These data suggest that the channel-forming action of PTX does not depend on the catalytic domain species...
  26. ncbi request reprint [Angina pectoris in hypertensive patients]
    Toshiaki Ishii
    Department of Cardiology, Surugadai Nihon University Hospital
    Nihon Rinsho 62:333-6. 2004