S Uchino

Summary

Affiliation: Noguchi Thyroid Clinic and Hospital Foundation
Country: Japan

Publications

  1. ncbi request reprint Modified radical neck dissection for differentiated thyroid cancer: operative technique
    Shinya Uchino
    Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi Beppu, 874 0932 Oita, Japan
    World J Surg 28:1199-203. 2004
  2. pmc Remission of anorexia nervosa after thyroidectomy: A report of two cases with Graves' disease and anorexia nervosa
    Hitoshi Noguchi
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932 Japan
    Thyroid Res 4:17. 2011
  3. ncbi request reprint Detection of asymptomatic differentiated thyroid carcinoma by neck ultrasonographic screening for familial nonmedullary thyroid carcinoma
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, 874 0932 Oita, Japan
    World J Surg 28:1099-102. 2004
  4. ncbi request reprint Mutational analysis of the APC gene in cribriform-morula variant of papillary thyroid carcinoma
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Noguchi Naka machi 6 33, Beppu, Oita, 874 0932, Japan
    World J Surg 30:775-9. 2006
  5. ncbi request reprint Familial nonmedullary thyroid carcinoma characterized by multifocality and a high recurrence rate in a large study population
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi, Beppu, Oita 874 0932, Japan
    World J Surg 26:897-902. 2002
  6. ncbi request reprint Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumors
    S Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Cancer Res 60:5553-7. 2000
  7. ncbi request reprint Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type
    S Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita
    Jpn J Cancer Res 90:1231-7. 1999
  8. ncbi request reprint Usefulness of endoscopic ultrasonography (EUS) in diagnosing esophageal infiltration of thyroid cancer
    A Ohshima
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    J Endocrinol Invest 24:564-9. 2001
  9. ncbi request reprint Indications for bilateral modified radical neck dissection in patients with papillary carcinoma of the thyroid
    A Ohshima
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932, Japan
    Arch Surg 135:1194-8; discussion 1199. 2000
  10. ncbi request reprint Predictive risk factors for postoperative tetany in female patients with Graves' disease
    H Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    J Am Coll Surg 192:465-8. 2001

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Modified radical neck dissection for differentiated thyroid cancer: operative technique
    Shinya Uchino
    Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi Beppu, 874 0932 Oita, Japan
    World J Surg 28:1199-203. 2004
    ..Taping of the carotid artery or sternocleidomastoid muscle is avoided unless the tumor invades these tissues. MRND is a safe procedure when performed by skilled, experienced surgeons...
  2. pmc Remission of anorexia nervosa after thyroidectomy: A report of two cases with Graves' disease and anorexia nervosa
    Hitoshi Noguchi
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932 Japan
    Thyroid Res 4:17. 2011
    ..A review of the literature is presented that suggest a heretofore unreported thyroid hormone, which is involved in the regulation of migration behavior, may be the responsible factor behind anorexia nervosa...
  3. ncbi request reprint Detection of asymptomatic differentiated thyroid carcinoma by neck ultrasonographic screening for familial nonmedullary thyroid carcinoma
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, 874 0932 Oita, Japan
    World J Surg 28:1099-102. 2004
    ..Because of the high incidence of intraglandular and lymph node metastases, we recommend screening with ultrasonography for early detection in family members of patients with FNMTC...
  4. ncbi request reprint Mutational analysis of the APC gene in cribriform-morula variant of papillary thyroid carcinoma
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Noguchi Naka machi 6 33, Beppu, Oita, 874 0932, Japan
    World J Surg 30:775-9. 2006
    ..Papillary thyroid cancer is one of the extracolonic manifestations of FAP. A characteristic histologic feature of this type of thyroid tumor is the cribriform-morula variant of papillary thyroid carcinoma (CMVPTC)...
  5. ncbi request reprint Familial nonmedullary thyroid carcinoma characterized by multifocality and a high recurrence rate in a large study population
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi, Beppu, Oita 874 0932, Japan
    World J Surg 26:897-902. 2002
    ..Because of the frequent presence of benign nodules, multifocality, and high rate of locoregional recurrence, total or near-total thyroidectomy with modified radical neck dissection in FNMTC patients is recommended...
  6. ncbi request reprint Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumors
    S Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Cancer Res 60:5553-7. 2000
    ..Germ-line MEN1 gene analysis can distinguish heritable from nonheritable parathyroid tumors, and MEN1 gene evaluation of patients with apparently sporadic parathyroid tumor is recommended before parathyroid surgery...
  7. ncbi request reprint Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary type
    S Uchino
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita
    Jpn J Cancer Res 90:1231-7. 1999
    ..These results suggest that mutations occur frequently in the RET coding region in addition to the previously reported mutation hot spots, and there is a different spectrum of mutations between sporadic and hereditary MTC...
  8. ncbi request reprint Usefulness of endoscopic ultrasonography (EUS) in diagnosing esophageal infiltration of thyroid cancer
    A Ohshima
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    J Endocrinol Invest 24:564-9. 2001
    ..EUS is useful in evaluating the esophageal infiltration of thyroid cancer. This method has the further advantage of detecting the exact depth of cancer invasion into the esophageal wall...
  9. ncbi request reprint Indications for bilateral modified radical neck dissection in patients with papillary carcinoma of the thyroid
    A Ohshima
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932, Japan
    Arch Surg 135:1194-8; discussion 1199. 2000
    ..Bilateral modified radical neck dissection is beneficial for patients at high risk for contralateral nodal recurrence...
  10. ncbi request reprint Predictive risk factors for postoperative tetany in female patients with Graves' disease
    H Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    J Am Coll Surg 192:465-8. 2001
    ..Serum 25(OH)D and alkaline phosphatase should be monitored in patients with Graves' disease...
  11. ncbi request reprint Changing trends and prognoses for patients with papillary thyroid cancer
    H Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation and the Department of Pathology and Anatomy, Oita Medical University, Beppu, Japan
    Arch Surg 133:1058-65. 1998
    ..To analyze differences in the demographic backgrounds, and in treatments, prognosis, and risk factors of patients with papillary thyroid cancer operated on from 1965 to 1990, by dividing them into 3 chronological groups...
  12. ncbi request reprint Reelevation of parathyroid hormone level after parathyroidectomy in patients with primary hyperparathyroidism: importance of decreased renal parathyroid hormone sensitivity
    Hiroyuki Yamashita
    Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
    Surgery 137:419-25. 2005
    ..We hypothesized that impaired peripheral sensitivity to parathyroid hormone (PTH) may play a role in reelevation of PTH after successful operation for primary hyperparathyroidism (pHPT)...
  13. ncbi request reprint Bronchoscopic diagnosis of thyroid cancer with laryngotracheal invasion
    E Koike
    Noguchi Thyroid Clinic, Oita, Japan
    Arch Surg 136:1185-9. 2001
    ..Other mucosal changes were found depending on the depth of cancer invasion. CONCLUSION: Surgeons should perform extensive resections when encountering localized mucosal redness on bronchoscopy...
  14. ncbi request reprint Thyroid evaluation in patients with primary hyperparathyroidism
    Toshihiro Masatsugu
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    Endocr J 52:177-82. 2005
    ..Eight (88.9%) of the 9 non-palpable thyroid cancers were accurately diagnosed by combined US and US-FNAB. Preoperative US is useful for evaluation of possible concomitant thyroid disease, especially for prediction of malignancy...
  15. ncbi request reprint Endoscopic ultrasonography in patients with thyroid cancer: its usefulness and limitations for evaluating esophagopharyngeal invasion
    E Koike
    Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Endoscopy 34:457-60. 2002
    ..In the present study, endoscopic ultrasonography (EUS) of the esophagus was used to assess esophagopharyngeal invasion by thyroid cancer, and the value of this technique was assessed prospectively...
  16. ncbi request reprint High prevalence of vitamin D deficiency in Japanese female patients with Graves' disease
    H Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    Endocr J 48:63-9. 2001
    ..2 +/- 13.7 nmol/l). Serum 25(OH)D concentrations might be monitored in patients with Graves' disease during antithyroid drug therapy, and vitamin D and/or calcium supplements are recommended for patients with vitamin D deficiency...
  17. pmc A case of cystadenocarcinoma of the ectopic salivary gland: comparison of pre-operative ultrasound, CT and MR images with the pathological specimen
    K Enomoto
    Department of Otolaryngology, Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Dentomaxillofac Radiol 41:349-54. 2012
    ....
  18. ncbi request reprint Total endoscopic and video-assisted thyroidectomy: cervical approach
    H Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita 874 0932, Japan
    Biomed Pharmacother 56:64s-67s. 2002
    ..Excellent cosmetic results were obtained by both procedures; however, video-assisted procedures required less time and a smaller dissection area...
  19. ncbi request reprint Large carboxy-terminal parathyroid hormone (PTH) fragment with a relatively longer half-life than 1-84 PTH is secreted directly from the parathyroid gland in humans
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
    Eur J Endocrinol 149:301-6. 2003
    ....
  20. doi request reprint The surgical strategy and the molecular analysis of patients with parathyroid cancer
    Keisuke Enomoto
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932, Japan
    World J Surg 34:2604-10. 2010
    ..In this study, we investigated its clinical significance in patients with parathyroid cancer and the association of gene mutations with tumor progression...
  21. doi request reprint Modified radical neck dissection is better than partial dissection of lymph nodes
    Shiro Noguchi
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita 874 0932, Japan
    World J Surg 33:394-6. 2009
    ..For papillary thyroid cancer, lymph node excision may be less important for smaller tumors and rather limited node excision might be sufficient to prevent recurrence...
  22. ncbi request reprint Video-assisted thyroid lobectomy through a small wound in the submandibular area
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, 874 0932, Beppu Oita, Japan
    Am J Surg 183:286-9. 2002
    ..We developed a video-assisted hemithyroidectomy procedure that requires only one small incision at the upper neck...
  23. pmc Papillary microcarcinoma
    Shiro Noguchi
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Japan
    World J Surg 32:747-53. 2008
    ..Papillary microcarcinoma (PMC) is increasing in incidence because of diagnosis by ultrasound-guided fine-needle aspiration cytology...
  24. ncbi request reprint Significance of an insular component in follicular thyroid carcinoma with distant metastasis at initial presentation
    Hiroto Yamashita
    Department of Research and Laboratory Medicine, Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Endocr Pathol 16:41-8. 2005
    ..The remaining older patient with an insular component but without distant metastasis showed a gradual increase in thyroglobulin levels after total thyroidectomy...
  25. ncbi request reprint Vitamin D status in Japanese patients with hyperparathyroidism: seasonal changes and effect on clinical presentation
    Hiroyuki Yamashita
    Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu 874 0932, Japan
    World J Surg 26:937-41. 2002
    ..Our study population was at an early stage of pHPT, so the vitamin D deficiency may not be associated with the effects of HPT...
  26. ncbi request reprint Influence of renal function on clinico-pathological features of primary hyperparathyroidism
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
    Eur J Endocrinol 148:597-602. 2003
    ..We studied the influence of renal function on the clinico-pathological characteristics of 141 patients (123 women and 18 men) with surgically proven pHPT...
  27. pmc Role of cyclase activating parathyroid hormone (1-84 PTH) measurements during parathyroid surgery: potential improvement of intraoperative PTH assay
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu Oita, Japan
    Ann Surg 236:105-11. 2002
    ..Using a CAP assay, the authors studied the rate of decline of CAP after parathyroidectomy and compared it with iPTH as measured by the Nichols intact PTH immunoradiometric assay...
  28. ncbi request reprint Crank-shaped sternotomy for upper mediastinal lymph node dissection in patients with differentiated thyroid cancer
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita 874 0932, Japan
    Surg Today 34:480-1. 2004
    ..This technique can be used for patients with thyroid cancer and mediastinal lymph node metastasis and for those with a mediastinal tumor or certain cardiac disorders...
  29. ncbi request reprint Intraoperative parathyroid hormone assay in patients with Graves' disease for prediction of postoperative tetany
    Taiki Moriyama
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
    World J Surg 29:1282-7. 2005
    ..We recommend IOPTH measurement as an adjunct to postoperative management of patients with Graves' disease to assist in preventing hypocalcemia and determining the earliest time for safe discharge...
  30. ncbi request reprint Sequential changes in plasma intact and whole parathyroid hormone levels during parathyroidectomy for secondary hyperparathyroidism
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, 874 0932 Beppu Oita, Japan
    World J Surg 29:169-73. 2005
    ....
  31. doi request reprint Intraoperative parathyroid hormone levels measured by intact and whole parathyroid hormone assays in patients with Graves' disease
    Masaya Kai
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
    Surg Today 38:214-21. 2008
    ..To find out if the whole parathyroid hormone (wPTH) assay has practical advantages over the intact (iPTH) assay in patients with Graves' disease...
  32. ncbi request reprint Comparison of parathyroid hormone levels from the intact and whole parathyroid hormone assays after parathyroidectomy for primary and secondary hyperparathyroidism
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, Beppu Oita, Japan
    Surgery 135:149-56. 2004
    ..Using a whole-molecule PTH (whole PTH) assay that specifically measured only 1-84 PTH, we compared the kinetics of whole PTH and intact PTH after parathyroidectomy in patients with primary hyperparathyroidism (HPT) and secondary HPT...
  33. ncbi request reprint [Necessity of registrar in medical institution]
    Shigeru Shutou
    Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Gan To Kagaku Ryoho 32:954-6. 2005
    ..In this paper, we report the role of the registrar and emphasize the necessity of a registrar...
  34. ncbi request reprint NIS mRNA expression level in resected thyroid tissue as a marker of postoperative hypothyroidism after subtotal thyroidectomy in patients with Graves' disease
    Aya Goto
    Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
    Endocr J 55:73-81. 2008
    ..Evaluation of NIS mRNA expression in thyroid tissues may help determine prognoses of Graves' disease patients, and therefore an appropriate treatment can be determined for each patient...
  35. ncbi request reprint Genetic analyses in patients with familial isolated hyperparathyroidism and hyperparathyroidism-jaw tumour syndrome
    Noriko Mizusawa
    Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    Clin Endocrinol (Oxf) 65:9-16. 2006
    ..AIM/PATIENTS AND METHODS: We investigated the involvement of the HRPT2, MEN1 and CASR genes in 11 provisional FIHP families and two HPT-JT families...
  36. ncbi request reprint Is a bilateral modified radical neck dissection beneficial for patients with papillary thyroid cancer?
    Akira Ohshima
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Faculty of Medicine, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka 812 8582, Japan
    Surg Today 32:1027-30. 2002
    ..The aim of this study was to investigate whether bilateral MRND improved prognosis in patients at risk for contralateral nodal recurrence...
  37. ncbi request reprint Biallelic inactivation by somatic mutations of the MEN1 gene in sporadic parathyroid tumors
    Chisato Tanaka
    Otsuka Department of Molecular Nutrition, School of Medicine, The University of Tokushima, 3 18 15 Kuramoto cho, 770 8503, Tokushima, Japan
    Cancer Lett 175:175-9. 2002
    ..The results directly confirmed the participation of MEN1 in the tumorigenesis of sporadic parathyroid tumors...
  38. ncbi request reprint Significant clinical differences in primary hyperparathyroidism between patients with and those without concomitant thyroid disease
    Toshihiro Masatsugu
    Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surg Today 35:351-6. 2005
    ..We evaluated the differences in diagnosis and treatment for primary hyperparathyroidism (pHPT) in patients with and those without concomitant thyroid disease...
  39. ncbi request reprint [Examination strategy for thyroid nodules]
    Shinya Uchino
    Noguchi Thyroid Clinic and Hospital Foundation
    Nihon Rinsho 65:2016-20. 2007
    ..Neck MRI and CT are useless examination for thyroid nodule except for giant goiter or intrathoracic goiter. In this article, we present a current, rational diagnostic strategy to the patients with a thyroid nodule...
  40. ncbi request reprint Novel 14 base-pair deletion of the MEN1 gene in a patient with recurrent primary hyperparathyroidism
    Miyuki Katai
    Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto 390 8621, Japan
    Jpn J Clin Oncol 36:395-7. 2006
    ..This deletional mutation has not previously been described elsewhere...
  41. ncbi request reprint Current status of clinical care for familial endocrine tumor syndromes in Japan
    Akihiro Sakurai
    Division of Medical Genetics, Department of Preventive Medicine, Shinshu University School of Medicine, Matsumoto
    Endocr J 52:757-62. 2005
    ..Only 27.8% of respondents have read the guidelines and understood their concepts...