Research Topics
Species | S UchinoSummaryAffiliation: Noguchi Thyroid Clinic and Hospital Foundation Country: Japan Publications
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Detail Information
Publications
Remission of anorexia nervosa after thyroidectomy: A report of two cases with Graves' disease and anorexia nervosaHitoshi Noguchi
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932 Japan
Thyroid Res 4:17. 2011..A review of the literature is presented that suggest a heretofore unreported thyroid hormone, which is involved in the regulation of migration behavior, may be the responsible factor behind anorexia nervosa...
Detection of asymptomatic differentiated thyroid carcinoma by neck ultrasonographic screening for familial nonmedullary thyroid carcinomaShinya Uchino
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, 874 0932 Oita, Japan
World J Surg 28:1099-102. 2004..Because of the high incidence of intraglandular and lymph node metastases, we recommend screening with ultrasonography for early detection in family members of patients with FNMTC...- Modified radical neck dissection for differentiated thyroid cancer: operative techniqueShinya Uchino
Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi Beppu, 874 0932 Oita, Japan
World J Surg 28:1199-203. 2004..Taping of the carotid artery or sternocleidomastoid muscle is avoided unless the tumor invades these tissues. MRND is a safe procedure when performed by skilled, experienced surgeons... - Mutational analysis of the APC gene in cribriform-morula variant of papillary thyroid carcinomaShinya Uchino
Noguchi Thyroid Clinic and Hospital Foundation, Noguchi Naka machi 6 33, Beppu, Oita, 874 0932, Japan
World J Surg 30:775-9. 2006..Papillary thyroid cancer is one of the extracolonic manifestations of FAP. A characteristic histologic feature of this type of thyroid tumor is the cribriform-morula variant of papillary thyroid carcinoma (CMVPTC)... - Familial nonmedullary thyroid carcinoma characterized by multifocality and a high recurrence rate in a large study populationShinya Uchino
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Naka machi, Beppu, Oita 874 0932, Japan
World J Surg 26:897-902. 2002..Because of the frequent presence of benign nodules, multifocality, and high rate of locoregional recurrence, total or near-total thyroidectomy with modified radical neck dissection in FNMTC patients is recommended... - Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumorsS Uchino
Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Cancer Res 60:5553-7. 2000..Germ-line MEN1 gene analysis can distinguish heritable from nonheritable parathyroid tumors, and MEN1 gene evaluation of patients with apparently sporadic parathyroid tumor is recommended before parathyroid surgery... - Somatic mutations in RET exons 12 and 15 in sporadic medullary thyroid carcinomas: different spectrum of mutations in sporadic type from hereditary typeS Uchino
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita
Jpn J Cancer Res 90:1231-7. 1999..These results suggest that mutations occur frequently in the RET coding region in addition to the previously reported mutation hot spots, and there is a different spectrum of mutations between sporadic and hereditary MTC... - Usefulness of endoscopic ultrasonography (EUS) in diagnosing esophageal infiltration of thyroid cancerA Ohshima
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
J Endocrinol Invest 24:564-9. 2001..EUS is useful in evaluating the esophageal infiltration of thyroid cancer. This method has the further advantage of detecting the exact depth of cancer invasion into the esophageal wall... - Indications for bilateral modified radical neck dissection in patients with papillary carcinoma of the thyroidA Ohshima
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932, Japan
Arch Surg 135:1194-8; discussion 1199. 2000..Bilateral modified radical neck dissection is beneficial for patients at high risk for contralateral nodal recurrence... - Predictive risk factors for postoperative tetany in female patients with Graves' diseaseH Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
J Am Coll Surg 192:465-8. 2001..Serum 25(OH)D and alkaline phosphatase should be monitored in patients with Graves' disease... - Changing trends and prognoses for patients with papillary thyroid cancerH Yamashita
Noguchi Thyroid Clinic and Hospital Foundation and the Department of Pathology and Anatomy, Oita Medical University, Beppu, Japan
Arch Surg 133:1058-65. 1998..To analyze differences in the demographic backgrounds, and in treatments, prognosis, and risk factors of patients with papillary thyroid cancer operated on from 1965 to 1990, by dividing them into 3 chronological groups... - Reelevation of parathyroid hormone level after parathyroidectomy in patients with primary hyperparathyroidism: importance of decreased renal parathyroid hormone sensitivityHiroyuki Yamashita
Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
Surgery 137:419-25. 2005..We hypothesized that impaired peripheral sensitivity to parathyroid hormone (PTH) may play a role in reelevation of PTH after successful operation for primary hyperparathyroidism (pHPT)... - Bronchoscopic diagnosis of thyroid cancer with laryngotracheal invasionE Koike
Noguchi Thyroid Clinic, Oita, Japan
Arch Surg 136:1185-9. 2001..Other mucosal changes were found depending on the depth of cancer invasion. CONCLUSION: Surgeons should perform extensive resections when encountering localized mucosal redness on bronchoscopy... - Thyroid evaluation in patients with primary hyperparathyroidismToshihiro Masatsugu
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
Endocr J 52:177-82. 2005..Eight (88.9%) of the 9 non-palpable thyroid cancers were accurately diagnosed by combined US and US-FNAB. Preoperative US is useful for evaluation of possible concomitant thyroid disease, especially for prediction of malignancy... - Endoscopic ultrasonography in patients with thyroid cancer: its usefulness and limitations for evaluating esophagopharyngeal invasionE Koike
Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Endoscopy 34:457-60. 2002..020). Conclusions. EUS is useful for assessing esophagopharyngeal invasion by thyroid cancer, although its effectiveness may be limited in thyroid lesions located in the upper part of the lobe... - High prevalence of vitamin D deficiency in Japanese female patients with Graves' diseaseH Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
Endocr J 48:63-9. 2001..2 +/- 13.7 nmol/l). Serum 25(OH)D concentrations might be monitored in patients with Graves' disease during antithyroid drug therapy, and vitamin D and/or calcium supplements are recommended for patients with vitamin D deficiency... 
A case of cystadenocarcinoma of the ectopic salivary gland: comparison of pre-operative ultrasound, CT and MR images with the pathological specimenK Enomoto
Department of Otolaryngology, Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Dentomaxillofac Radiol 41:349-54. 2012....- Total endoscopic and video-assisted thyroidectomy: cervical approachH Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita 874 0932, Japan
Biomed Pharmacother 56:64s-67s. 2002..Excellent cosmetic results were obtained by both procedures; however, video-assisted procedures required less time and a smaller dissection area... - Large carboxy-terminal parathyroid hormone (PTH) fragment with a relatively longer half-life than 1-84 PTH is secreted directly from the parathyroid gland in humansHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
Eur J Endocrinol 149:301-6. 2003.... - The surgical strategy and the molecular analysis of patients with parathyroid cancerKeisuke Enomoto
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita, 874 0932, Japan
World J Surg 34:2604-10. 2010..In this study, we investigated its clinical significance in patients with parathyroid cancer and the association of gene mutations with tumor progression... - Modified radical neck dissection is better than partial dissection of lymph nodesShiro Noguchi
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu, Oita 874 0932, Japan
World J Surg 33:394-6. 2009..For papillary thyroid cancer, lymph node excision may be less important for smaller tumors and rather limited node excision might be sufficient to prevent recurrence... - Video-assisted thyroid lobectomy through a small wound in the submandibular areaHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, 874 0932, Beppu Oita, Japan
Am J Surg 183:286-9. 2002..We developed a video-assisted hemithyroidectomy procedure that requires only one small incision at the upper neck... - Papillary microcarcinomaShiro Noguchi
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Japan
World J Surg 32:747-53. 2008..Papillary microcarcinoma (PMC) is increasing in incidence because of diagnosis by ultrasound-guided fine-needle aspiration cytology... - Significance of an insular component in follicular thyroid carcinoma with distant metastasis at initial presentationHiroto Yamashita
Department of Research and Laboratory Medicine, Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Endocr Pathol 16:41-8. 2005..The remaining older patient with an insular component but without distant metastasis showed a gradual increase in thyroglobulin levels after total thyroidectomy... - Vitamin D status in Japanese patients with hyperparathyroidism: seasonal changes and effect on clinical presentationHiroyuki Yamashita
Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu 874 0932, Japan
World J Surg 26:937-41. 2002..Our study population was at an early stage of pHPT, so the vitamin D deficiency may not be associated with the effects of HPT... - Influence of renal function on clinico-pathological features of primary hyperparathyroidismHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
Eur J Endocrinol 148:597-602. 2003..We studied the influence of renal function on the clinico-pathological characteristics of 141 patients (123 women and 18 men) with surgically proven pHPT... - Role of cyclase activating parathyroid hormone (1-84 PTH) measurements during parathyroid surgery: potential improvement of intraoperative PTH assayHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, Beppu Oita, Japan
Ann Surg 236:105-11. 2002..These results suggest that the CAP assay may be a more useful adjunct to parathyroidectomy than the currently used iPTH assay... - Crank-shaped sternotomy for upper mediastinal lymph node dissection in patients with differentiated thyroid cancerHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6-33 Noguchi-Nakamachi, Beppu, Oita 874-0932, Japan
Surg Today 34:480-1. 2004..This technique can be used for patients with thyroid cancer and mediastinal lymph node metastasis and for those with a mediastinal tumor or certain cardiac disorders... - Intraoperative parathyroid hormone assay in patients with Graves' disease for prediction of postoperative tetanyTaiki Moriyama
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, Beppu Oita 874 0932, Japan
World J Surg 29:1282-7. 2005..We recommend IOPTH measurement as an adjunct to postoperative management of patients with Graves' disease to assist in preventing hypocalcemia and determining the earliest time for safe discharge... - Sequential changes in plasma intact and whole parathyroid hormone levels during parathyroidectomy for secondary hyperparathyroidismHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, 874 0932 Beppu Oita, Japan
World J Surg 29:169-73. 2005.... - Intraoperative parathyroid hormone levels measured by intact and whole parathyroid hormone assays in patients with Graves' diseaseMasaya Kai
Noguchi Thyroid Clinic and Hospital Foundation, Beppu, Oita, Japan
Surg Today 38:214-21. 2008..To find out if the whole parathyroid hormone (wPTH) assay has practical advantages over the intact (iPTH) assay in patients with Graves' disease... - Comparison of parathyroid hormone levels from the intact and whole parathyroid hormone assays after parathyroidectomy for primary and secondary hyperparathyroidismHiroyuki Yamashita
Noguchi Thyroid Clinic and Hospital Foundation, Beppu Oita, Japan
Surgery 135:149-56. 2004.... - [Necessity of registrar in medical institution]Shigeru Shutou
Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Gan To Kagaku Ryoho 32:954-6. 2005..In this paper, we report the role of the registrar and emphasize the necessity of a registrar... - NIS mRNA expression level in resected thyroid tissue as a marker of postoperative hypothyroidism after subtotal thyroidectomy in patients with Graves' diseaseAya Goto
Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan
Endocr J 55:73-81. 2008..Evaluation of NIS mRNA expression in thyroid tissues may help determine prognoses of Graves' disease patients, and therefore an appropriate treatment can be determined for each patient... - Genetic analyses in patients with familial isolated hyperparathyroidism and hyperparathyroidism-jaw tumour syndromeNoriko Mizusawa
Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
Clin Endocrinol (Oxf) 65:9-16. 2006..No mutations of CASR were detected. CONCLUSION: Our results confirm the need to test for HRPT2 in FIHP families, especially those with parathyroid carcinomas, atypical adenomas or adenomas with cystic change... - Is a bilateral modified radical neck dissection beneficial for patients with papillary thyroid cancer?Akira Ohshima
Department of Surgery and Oncology, Graduate School of Medical Sciences, Faculty of Medicine, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka 812 8582, Japan
Surg Today 32:1027-30. 2002..The aim of this study was to investigate whether bilateral MRND improved prognosis in patients at risk for contralateral nodal recurrence... - Biallelic inactivation by somatic mutations of the MEN1 gene in sporadic parathyroid tumorsChisato Tanaka
Otsuka Department of Molecular Nutrition, School of Medicine, The University of Tokushima, 3-18-15 Kuramoto-cho, 770-8503, Tokushima, Japan
Cancer Lett 175:175-9. 2002..The results directly confirmed the participation of MEN1 in the tumorigenesis of sporadic parathyroid tumors... - Significant clinical differences in primary hyperparathyroidism between patients with and those without concomitant thyroid diseaseToshihiro Masatsugu
Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Surg Today 35:351-6. 2005..Thyroid disease concomitant with pHPT influenced parathyroid localization as well as the indication for minimally invasive parathyroidectomy... - [Examination strategy for thyroid nodules]Shinya Uchino
Noguchi Thyroid Clinic and Hospital Foundation
Nihon Rinsho 65:2016-20. 2007..Neck MRI and CT are useless examination for thyroid nodule except for giant goiter or intrathoracic goiter. In this article, we present a current, rational diagnostic strategy to the patients with a thyroid nodule... - Novel 14 base-pair deletion of the MEN1 gene in a patient with recurrent primary hyperparathyroidismMiyuki Katai
Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
Jpn J Clin Oncol 36:395-7. 2006..This deletional mutation has not previously been described elsewhere... - Current status of clinical care for familial endocrine tumor syndromes in JapanAkihiro Sakurai
Division of Medical Genetics, Department of Preventive Medicine, Shinshu University School of Medicine, Matsumoto
Endocr J 52:757-62. 2005..Only 27.8% of respondents have read the guidelines and understood their concepts...