Research Topics
| Masato NishimuraSummaryCountry: Japan Publications
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Publications
Myocardial fatty acid imaging identifies a group of hemodialysis patients at high risk for cardiac death after coronary revascularizationMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Kidney Int 74:513-20. 2008..These results suggest that myocardial fatty acid imaging may be a useful test to identify high risk groups of cardiac death in hemodialysis patients...
Sympathetic overactivity and sudden cardiac death among hemodialysis patients with left ventricular hypertrophyMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Int J Cardiol 142:80-6. 2010..We prospectively investigated whether cardiac autonomic imbalance is associated with sudden cardiac death (SCD) among a group of hemodialysis patients with left ventricular hypertrophy (LVH)...
Close association of Chlamydia pneumoniae IgA seropositivity by ELISA with the presence of coronary artery stenosis in haemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, 16 Negoro, Momoyama cho, Fushimi ku, Kyoto, 612 8024 Japan
Nephrol Dial Transplant 20:1944-50. 2005....
Insulin resistance and impaired myocardial fatty acid metabolism in dialysis patients with normal coronary arteriesM Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Kidney Int 69:553-9. 2006..0+/-13.6%, n=11, P=0.0007). Association between insulin resistance and impaired cardiac fatty acid metabolism may contribute to left ventricular dysfunction in patients with maintenance hemodialysis without coronary diseases...
Association of the circulating adiponectin concentration with coronary in-stent restenosis in haemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, 83 1, Iga, Kyoto 612 8026, Japan
Nephrol Dial Transplant 21:1640-7. 2006....
Risk stratification for cardiac death in hemodialysis patients without obstructive coronary artery diseaseMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Kidney Int 79:363-71. 2011..9-98.7%) above, equal to, or below the thresholds. Thus, impaired myocardial fatty acid metabolism and insulin resistance may be associated with cardiac death among hemodialysis patients without obstructive coronary artery disease...
Influence of diabetes mellitus on diagnostic potential of iodine-123-BMIPP imaging for coronary artery stenosis in hemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, and Department of Clinical Sciences and Laboratory Medicine, Kansai Medical University, Hirakata, Japan
J Nephrol 19:481-91. 2006..In this study, we investigated whether the presence of diabetes mellitus may affect the diagnostic potential of BMIPP SPECT for detecting coronary stenosis in ESRD patients...
Upregulation of the brain renin-angiotensin system in rats with chronic renal failureM Nishimura
Cardiovascular Division, Toujinkai Hospital, Iga, Kyoto, Japan
Acta Physiol (Oxf) 189:369-77. 2007..We investigated how the brain renin-angiotensin system is involved in regulation of the sympathetic activity and arterial pressure in rats with chronic renal failure...
Oral nicorandil to reduce cardiac death after coronary revascularization in hemodialysis patients: a randomized trialMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Am J Kidney Dis 54:307-17. 2009..We examined whether oral administration of nicorandil, a hybrid nitrate and adenosine triphosphate-sensitive potassium channel opener, could improve outcome after coronary revascularization in hemodialysis patients...
Prediction of cardiac death in hemodialysis patients by myocardial fatty acid imagingMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
J Am Coll Cardiol 51:139-45. 2008....
Association of insulin resistance with de novo coronary stenosis after percutaneous coronary artery intervention in hemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Nephron Clin Pract 109:c9-17. 2008..We aimed to clarify the factors associated with de novocoronary lesion in this population...
Clinical potential of nicorandil to inhibit major cardiac events in hemodialysis patients with suspected myocardial ischemiaMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Fushimi ku, Kyoto, Japan
Nephron Clin Pract 111:c212-21. 2009....
Clinical utility of myocardial fatty acid imaging in patients with end-stage renal diseaseMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Fushimi ku, Kyoto, Japan
J Nucl Cardiol 15:830-7. 2008..Myocardial fatty acid imaging may be a new modality to detect myocardial ischemia and identify the group at high risk for cardiac death among ESRD patients without adding any stress...
Chronic reductions in carotid blood flow cause salt-sensitive hypertension in ratsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
J Hypertens 23:1173-81. 2005..We determined whether chronic reductions in carotid blood flow elicit salt-sensitive hypertension through regulation of the brain renin-angiotensin system (RAS)...
[Potential of plasma adiponectin concentrations as a predictive marker for in-stent restenosis after percutaneous coronary intervention in patients on hemodialysis]Masato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto 612 8026, Japan
Rinsho Byori 59:795-800. 2011..2 +/- 10.8 microg/ml (17.9-79.8 microg/ml; n=34); p = 0.0001]. Circulating adiponectin concentrations may be associated with the occurrence of coronary in-stent restenosis in ESRD patients undergoing maintenance hemodialysis...
Oral nicorandil for prevention of cardiac death in hemodialysis patients without obstructive coronary artery disease: a propensity-matched patient analysisMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kansai Medical University, Osaka, Japan
Nephron Clin Pract 119:c301-9. 2011..We examined the potential of oral administration of nicorandil for protecting against cardiac death in hemodialysis patients without obstructive coronary artery disease...
Association between cardiovascular autonomic neuropathy and left ventricular hypertrophy in diabetic haemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, 16 Negoro, Momoyama cho, Fushimi ku, Kyoto 612 8024, Japan
Nephrol Dial Transplant 19:2532-8. 2004..We investigated whether cardiovascular autonomic neuropathy is associated with left ventricular hypertrophy (LVH) in diabetic haemodialysis patients...
Myocardial scintigraphy using a fatty acid analogue detects coronary artery disease in hemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Kidney Int 66:811-9. 2004..895 in BMIPP and 0.727 in Tl SPECT, respectively. CONCLUSION: Resting BMIPP SPECT is superior to Tl SPECT for detecting coronary lesions, and provides safe screening for coronary artery disease among maintenance hemodialysis patients...
Possible involvement of TNF-alpha in left ventricular remodeling in hemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
J Nephrol 16:641-9. 2003..We investigated whether increased circulating TNF-alpha is associated with left ventricular remodeling against pressure and/or volume overload in HD patients with or without diabetes mellitus...
Total parathyroidectomy improves survival of hemodialysis patients with secondary hyperparathyroidismNoriyuki Iwamoto
Department of Urology, Tojinkai Hospital, Kyoto, Japan
J Nephrol 25:755-63. 2012..To compare the prognosis of chronic hemodialysis patients with or without parathyroidectomy...
The high incidence of left atrial appendage thrombosis in patients on maintenance haemodialysisMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Momoyama cho, Kyoto, Japan
Nephrol Dial Transplant 18:2339-47. 2003..The incidence of intracardiac thrombosis in haemodialysis patients has not been studied. Here we determined the incidence in end-stage renal disease patients on maintenance haemodialysis...
Different remodelling against left ventricular overload between diabetic and non-diabetic haemodialysis patientsMasato Nishimura
Cardiovascular Division, Toujinkai Hospital, Kyoto, Japan
Clin Exp Pharmacol Physiol 30:786-92. 2003..This difference in left ventricular remodelling against left ventricular overload may be associated with the high incidence of congestive heart failure in diabetic haemodialysis patients...
Effect of vasodilatory beta-adrenoceptor blockers on cardiovascular haemodynamics in anaesthetized ratsHakuo Takahashi
Department of Clinical Science and Laboratory Medicine, Kansai Medical University, Moriguchi, Japan
Clin Exp Pharmacol Physiol 29:198-203. 2002....
Renin-angiotensin system in proliferative diabetic retinopathy and its gene expression in cultured human müller cellsTeruyo Kida
Department of Ophthalmology, Osaka Medical College, Osaka, Japan
Jpn J Ophthalmol 47:36-41. 2003..CONCLUSIONS: The RAS is locally activated in eyes with PDR, and Müller cells may play a role in this local activation...
The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brainHakuo Takahashi
Department of Clinical Sciences and Laboratory Medicine, Kansai Medical University, Hirakata City, Osaka, Japan
Hypertens Res 34:1147-60. 2011..This report provides an overview of the central mechanism underlying hypertension and discusses the use of antihypertensive agents...
Role of FMRFamide-activated brain sodium channel in salt-sensitive hypertensionM Nishimura
Department of Clinical and Laboratory Medicine, Kyoto Prefectural University of Medicine, Kamikyo ku, Kyoto, Japan
Hypertension 35:443-50. 2000..Together, these findings suggest that brain FMRFamide-activated sodium channels may be involved in the mechanism of salt-sensitive hypertension through regulation of the brain renin-angiotensin system...
Anti-obesity and anti-diabetic effects of carteolol in non-insulin-dependent diabetic miceH Takahashi
Department of Clinical Sciences, Kansai Medical University, Osaka, Japan
Clin Exp Pharmacol Physiol 21:477-83. 1994..4. Since brown adipose tissue (BAT) is closely associated with thermogenesis and energy consumption, we tested whether carteolol may affect BAT.(ABSTRACT TRUNCATED AT 250 WORDS)..
Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation end productsN Nakamura
The First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
Free Radic Biol Med 29:17-25. 2000....
Prognostic utility of plasma S100A12 levels to establish a novel scoring system for predicting mortality in maintenance hemodialysis patients: a two-year prospective observational study in JapanYayoi Shiotsu
Division of Nephrology, Department of Medicine, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto, Japan
BMC Nephrol 14:16. 2013..S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined...
Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic isletsZ P Shen
Department of Metabolism and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan
Diabetes Res Clin Pract 53:9-16. 2001....
[Renal autotransplantation in a patient with acute renal infarction following surgery for a dissecting aneurysm]N Tamura
Department of Cardiovascular Surgery, Otowa Hospital, Kyoto, Japan
Kyobu Geka 54:188-90. 2001....
Apomorphine up-regulates NGF and GDNF synthesis in cultured mouse astrocytesM Ohta
Clinical Research Center, Utano National Hospital, Kyoto, Japan
Biochem Biophys Res Commun 272:18-22. 2000..9-fold of the control level at 15 h. These results suggest that apomorphine may exert neuroprotective effects by stimulation of NGF and GDNF synthesis in astrocytes...
Centrally induced vasopressor and sympathetic responses to a novel endogenous peptide, adrenomedullin, in anesthetized ratsH Takahashi
Department of Clinical Sciences and Laboratory Medicine, Kansai Medical University, Osaka, Japan
Am J Hypertens 7:478-82. 1994..Or, CGRP and adrenomedullin may share the same receptors, particularly in the brain...
[Limitation on efficacy of sirolimus-eluting stent implantation in patients on hemodialysis]Kenji Suzuki
Department of Cardiology, Sendai Kosei Hospital, Hirose cho 4 15, Aoba ku, Sendai 980 0873
J Cardiol 49:331-6. 2007..This study investigated the efficacy of SES for patients on hemodialysis compared with bare metal stent (BMS)...
[Neoadjuvant chemotherapy followed by radical surgery compared to concurrent chemotherapy in stage I b2- III b cervical cancer]Akiko Abe
Dept of Gynecology, Oe kyoudou Hospital
Gan To Kagaku Ryoho 35:1535-9. 2008..In addition, there was no significant difference in 3-year relapse-free survival or overall survival. When we consider the bias, these results suggest that CCRT is superior to NAC-S...
Effects of anthocyanidin derivative (HK-008) on relaxation in rat perfused mesenterial bedKatsuo Kamata
Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University, Ebara 2 4 41, Shinagawa ku, Tokyo 142 8501, Japan
J Smooth Muscle Res 42:75-88. 2006..These results suggest that HK-008 increases endothelium-induced relaxation by suppressing oxidative stress or modulating prostanoids signaling. This compound may therefore be useful against certain cardiovascular disorders...
