Research Topics
| Hiroyuki YokotaSummaryAffiliation: Nippon Medical School Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Cerebral endothelial injury in severe head injury: the significance of measurements of serum thrombomodulin and the von Willebrand factorHiroyuki Yokota
Department of Emergency and Critical Care, Tama Nagayama Hospital, Nippon Medical School, Tokyo, Japan
J Neurotrauma 19:1007-15. 2002..The levels of serum TM and vWf appear to be good indicators of the cerebral endothelial injury and of endothelial activation in severe head injury...- Regional cerebral blood flow in delirium patientsHiroyuki Yokota
Department of Emergency and Critical Care, Tama Nagayama Hospital, Nippon Medical School, Tokyo, Japan
Psychiatry Clin Neurosci 57:337-9. 2003..After recovery from delirium the rCBF of both areas returned to normal. The findings that reduced rCBF during delirium becomes normal once delirium improves suggest that a possible cause of delirium may be the cerebral hypoperfusion... - Cerebral endothelial damage after severe head injuryHiroyuki Yokota
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 74:332-7. 2007.... - Significance of magnetic resonance imaging in the diagnosis of vertebral artery injury associated with blunt cervical spine traumaHiroyuki Yokota
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School Hospital, Tokyo, Japan
J Nippon Med Sch 74:293-9. 2007.... 
Time course of recovery from cerebral vulnerability after severe traumatic brain injury: a microdialysis studyShoji Yokobori
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
J Trauma 71:1235-40. 2011....- Cerebral endothelial injury in elderly patients with severe head injury measured by serum thrombomodulin and von Willebrand factorHiroyuki Yokota
Department of Emergency and Critical Care Medicine, Main Hospital, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 47:383-8; discussion 388. 2007.... - Clinical analysis of spinal cord injury with or without cervical ossification of the posterior longitudinal ligament, spondylosis, and canal stenosis in elderly head injury patientsRyuta Nakae
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 50:461-5. 2010..To decrease the occurrence of cervical myelopathy, prevention by increasing social awareness and avoiding traffic accidents and falls is important... - Lower extracellular glucose level prolonged in elderly patients with severe traumatic brain injury: a microdialysis studyShoji Yokobori
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 51:265-71. 2011..We concluded that neural vulnerability persisted longer in elderly patients than in young patients with TBI, and this should be considered to prevent the occurrence of additional secondary brain injury... - Global end-diastolic volume is associated with the occurrence of delayed cerebral ischemia and pulmonary edema after subarachnoid hemorrhageAkihiro Watanabe
Departments of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Shock 38:480-5. 2012..58, P = 0.001), EVLW and CVP were not correlated (r = 0.03, P = 0.88). Thus, GEDI might be associated with DCI occurrence and EVLW accumulation after SAH... - [Case of carbon monoxide poisoning with the lesions demonstrated as abnormal intensity in the basal part of the left temporal lobe by MR image in acute phase]Ryuta Nakae
Department of Emergency and Critical Care Medicine, Nippon Medical School
Chudoku Kenkyu 19:273-8. 2006.... - Plasma neutrophil elastase correlates with pulmonary vascular permeability: a prospective observational study in patients with pneumoniaTakashi Tagami
Department of Emergency and Critical Care Medicine, Aidu Chuo Hospital, Fukushima, Japan
Respirology 16:953-8. 2011..The aims of this study were (i) to investigate PNE levels in patients with CAP and (ii) to explore the relationship between PNE and pulmonary vascular permeability... 
Effectiveness of human atrial natriuretic peptide supplementation in pulmonary edema patients using the pulse contour cardiac output systemYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Chiba Hokusou Hospital, Nippon Medical School 1715, Kamakari, Inba mura, Inba gun, Chiba 270 1694, Japan
Yonsei Med J 51:354-9. 2010....- Cerebral vasospasms after intraventricular hemorrhage from an arteriovenous malformation: case reportShoji Yokobori
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 50:320-3. 2010..Treatment of patients with AVM rupture should consider the risk of severe vasospasm, even if there is no subarachnoid clot... - Surgical venous thrombectomy for Japanese patients with acute deep vein thrombosis: a review of 5 years' experienceNoriyoshi Kutsukata
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Kamagari, Inba mura, Inba mura, Chiba, Japan
J Nippon Med Sch 77:155-9. 2010..Deep vein thrombosis (DVT) is a major risk factor for pulmonary thromboembolism (PTE). We carefully selected patients for surgical thrombectomy to treat acute-phase thrombosis and obtained favorable results... - Role of resuscitative emergency field thoracotomy in the Japanese helicopter emergency medical service systemHisashi Matsumoto
Shock and Trauma Center, Chiba Hokusoh Hospital, Nippon Medical School, Inba, Chiba, Japan
Resuscitation 80:1270-4. 2009..We investigated whether emergency thoracotomy (ET) performed in pre-hospital settings contributed to saving the lives of blunt trauma patients with impending or recent cardiac arrest... - Effectiveness of early start of direct hemoperfusion with polymyxin B-immobilized fiber columns judging from stabilization in circulatory dynamics in surgical treatment patientsYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Japan
Indian J Crit Care Med 14:35-9. 2010..In 1994, direct hemoperfusion using a polymyxin B-immobilized fiber column (PMX; Toray Industries Inc., Tokyo Japan) was developed in Japan and has since been used for the treatment of septic shock arising from endotoxemia... - Medical relief activities conducted by Nippon Medical School in the acute phase of the Great East Japan Earthquake 2011Akira Fuse
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 78:397-400. 2011..Such integrated systems should be designed around seamless connectivity based on an "always best connected" principle for maintaining communication quality... - Onsite medical rounds and fact-finding activities conducted by Nippon Medical School in Miyagi prefecture after the Great East Japan Earthquake 2011Akira Fuse
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 78:401-4. 2011..We must provide medical relief according to the unique characteristics of the disaster-affected areas as well as the specific nature of the disaster, in this case, a tsunami... - Adsorption of various antimicrobial agents to endotoxin removal polymyxin-B immobilized fiber (Toraymyxin®)Ken ichi Shimokawa
Department of Pharmaceutical Sciences, Meiji Pharmaceutical University, Tokyo, Japan
Colloids Surf B Biointerfaces 90:58-61. 2012.... - 'Pipe-organ'-like retroperitoneal drainage in severe necrotizing pancreatitisYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, 270 1694, Japan
Indian J Gastroenterol 29:34-6. 2010..This procedure can avoid gastrointestinal fistula and local bleeding without necessitating surgery... - The clinical usefulness of procalcitonin measurement for assessing the severity of bacterial infection in critically ill patients requiring corticosteroid therapyShigeki Kushimoto
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 74:236-40. 2007..The purpose of this study was to evaluate the clinical usefulness of PCT measurement for assessing the severity of bacterial infection in patients requiring corticosteroid therapy... - Medical relief activities, medical resourcing, and inpatient evacuation conducted by Nippon Medical School due to the Fukushima Daiichi Nuclear Power Plant accident following the Great East Japan Earthquake 2011Atsushi Koyama
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 78:393-6. 2011..At the same time, however, to overcome any future bureaucratic issues, we should also prepare private networks, such as those used by NMS, because they can respond flexibly to unexpected large-scale disasters... - Effectiveness of endotoxin scattering photometry for determining the efficacy of polymyxin B-immobilized fiber treatment in septic shock: report of a caseYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School
J Nippon Med Sch 77:119-22. 2010..We conclude that endotoxin measurement with endotoxin scattering photometry is superior to nephelometry in patients with endotoxemia... - Systemic inflammatory response syndrome score at admission predicts injury severity, organ damage and serum neutrophil elastase production in trauma patientsYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, Japan
J Nippon Med Sch 77:138-44. 2010..Systemic inflammatory response syndrome (SIRS) is a clinical condition representing the culmination of the activation of a complex network of acute endogenous mediators... - Selection of acute blood purification therapy according to severity score and blood lactic acid value in patients with septic shockYuichiro Sakamoto
Department of Emergency and Critical Care Medicine, Chiba Hokuso Hospital, Nippon Medical School, Japan
Indian J Crit Care Med 14:175-9. 2010.... - Measurement of inflammatory cytokines and thrombomodulin in chronic subdural hematomaMasatoshi Kitazono
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 52:810-5. 2012..The present findings suggest that the types of CSDH associated with high TM levels tend to have higher recurrence rate... - Postoperative course after simple ligation for superior mesenteric vein injury caused by blunt abdominal trauma: report of a caseMasato Miyauchi
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 78:116-9. 2011..The patient was discharged on POD 37. This case demonstrates that simple ligation of the proximal SMV leads to the development of collateral vessels and is useful for preventing side effects and improving outcomes... - [Primary oculomotor nerve palsy due to mild head injury--report of two cases]Makoto Katsuno
Department of Neurosurgery, Nippon Medical School, Chiba Hokuso Hospital, Inba gun, Chiba, Japan
Brain Nerve 60:89-91. 2008..We speculate that these perforating fibers at the anterior petroclinoidal liqament acted as a fulcrum due to downward displacement of the brainstem at the time of impact... - [Cerebral salt wasting syndrome and traumatic vasospasm after head trauma: report of two cases]Makoto Katsuno
Department of Neurosurgery Neurological Institute, Chiba Hokuso Hospital, Nippon Medical School, Tokyo, Japan
No Shinkei Geka 37:793-6. 2009..Our findings suggested hypothalamic dysfunction due to venous congestion around the hypothalamus caused cerebral salt wasting syndrome and traumatic cerebral arterial spasms... - Transcranial Doppler ultrasonography for diagnosis of cerebral vasospasm after aneurysmal subarachnoid hemorrhage: mean blood flow velocity ratio of the ipsilateral and contralateral middle cerebral arteriesRyuta Nakae
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Neurosurgery 69:876-83; discussion 883. 2011..Transcranial Doppler (TCD) is widely accepted to monitor cerebral vasospasm after subarachnoid hemorrhage (SAH); however, its predictive value remains controversial... - Damage control surgery and open abdominal management: recent advances and our approachShigeki Kushimoto
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School
J Nippon Med Sch 76:280-90. 2009..This technique may reduce the need for skin grafting and subsequent reconstruction and can be considered as an alternative method for the early management of patients with open abdomen... - The novel selective toll-like receptor 4 signal transduction inhibitor tak-242 prevents endotoxaemia in conscious Guinea-pigsMasamune Kuno
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Clin Exp Pharmacol Physiol 36:589-93. 2009..4. In conlusion, the results of the present study show that TAK-242 inhibited the symptoms associated with endotoxaemia in a guinea-pig model of sepsis and that it may, therefore, be an effective treatment for sepsis... - Implementation of the fifth link of the chain of survival concept for out-of-hospital cardiac arrestTakashi Tagami
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Circulation 126:589-97. 2012..Our study aimed to determine the effectiveness of this fifth link... - Visceral ischemia caused by acute aortic dissection following blunt aortic injury: report of a caseShigeki Kushimoto
Division of Emergency Medicine, Tohoku University Graduate School of Medicine, Tokyo, Japan
J Nippon Med Sch 78:110-5. 2011.... - Bilateral traumatic abducens nerve palsy associated with skull base fracture--case reportMakoto Katsuno
Department of Emergency and Critical Care, Nippon Medical School, Tokyo
Neurol Med Chir (Tokyo) 47:307-9. 2007..Chalasia of Gruber's ligament then exerted mechanical pressure on the bilateral abducens nerves... - [Present state of initial treatment of neurological abnormalities and the development faculties of emergency physicians]Kyoko Unemoto
Department of Emergency and Critical Care Medicine, Nippon Medical School, Musashikosugi Hospital, 1 396 Musashikosugi, Nakahara ku, Kawasaki, Kanagawa 211 8533, Japan
Brain Nerve 62:35-42. 2010..This report describes a strategy for accurate diagnosis and medical treatment of neurological abnormalities at the emergency rooms of hospitals, which are expected to provide this support... - [Case report of anesthesia with veno-veno extracorporeal membrane oxygenation (V-V ECMO) during one-lung ventilation for acute respiratory distress syndrome (ARDS) complicated with severe sepsis due to spontaneous esophageal rupture]Yuichi Ono
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo 113 8602
Masui 61:1137-40. 2012..Unfortunately, postoperative day 11, he died because of sudden intrathoracic bleeding from the thoracic aorta which might have been infected by the severe mediastinitis... - Validation of extravascular lung water measurement by single transpulmonary thermodilution: human autopsy studyTakashi Tagami
Department of Emergency and Critical Care Medicine, Aidu Chuo Hospital, 1 1 Tsuruga, Aiduwakamatsu, Fukushima, 965 8611, Japan
Crit Care 14:R162. 2010..The aims of this study were (1) to validate the accuracy of EVLW measurement by single transpulmonary thermodilution with postmortem lung weight measurement in humans and (2) to define the statistically normal EVLW values... - An analysis of Japan Disaster Medical Assistance Team (J-DMAT) deployments in comparison with those of J-DMAT's counterpart in the United States (US-DMAT)Akira Fuse
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 77:318-24. 2010..This means that J-DMATs have to be compact. The fact that J-DMATs are smaller and more agile than US-DMATs is a result of the types of disaster that hit Japan and the relatively small size of the country... - Pediatric posterior reversible leukoencephalopathy syndrome and NSAID-induced acute tubular interstitial nephritisShoji Yokobori
Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
Pediatr Neurol 34:245-7. 2006..One should consider reversible posterior leukoencephalopathy syndrome as a side effect of nonsteroidal anti-inflammatory drug use in daily medical treatment... - [Revised organ transplantation act in Japan from the view of emergency doctors]Hiroyuki Yokota
Department of Critical Care and Traumatology, Graduate School of Medicine, Nippon Meidical School, Bunkyo ku, Tokyo, Japan
Brain Nerve 62:565-73. 2010..Organ procurement is strictly regulated by legal guidelines; we propose that under the revised legal framework, the procedure of organ procurement be rapid... - Comparison of outcomes after use of biphasic or monophasic defibrillators among out-of-hospital cardiac arrest patients: a nationwide population-based observational studySeizan Tanabe
Emergency Life Saving Technique Academy of Tokyo, 4 5 Minamiosawa, Hachioji, Tokyo, Japan
Circ Cardiovasc Qual Outcomes 5:689-96. 2012.... - Fasudil, a Rho-kinase inhibitor, attenuates lipopolysaccharide-induced vascular hyperpermeability and colonic muscle relaxation in guinea pigsKensuke Suzuki
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan
J Surg Res 178:352-7. 2012..The goal of the present study was to determine the role of the Rho/Rho-kinase signal pathway in the pathogenesis of lipopolysaccharide (LPS)-induced vascular hyperpermeability using the Rho-kinase inhibitor fasudil... - Lessons learned from the Japan earthquake and tsunami, 2011Akira Fuse
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 79:312-5. 2012..We propose a descriptive device that can guide headquarters in dealing with the commonalities of a disaster... - [Risk factors of heatstroke]Hidetaka Onda
Department of Emergency and Critical Care Medicine, Nippon Medical School
Nihon Rinsho 70:947-51. 2012..For effective heatstroke prevention, however, many factors such as work environment and everyday life environment must be taken into account... - Increased regional interleukin-4 during the acute stage of severe intracranial disordersMakoto Katsuno
Department of Emergency and Critical Care, Nippon Medical School, Tokyo, Japan
Neurol Med Chir (Tokyo) 46:471-4; discussion 474-5. 2006..This finding suggests that secretion of IL-4, which has a neuroprotective effect, may increase with the severity of neuropathy and may be useful as a prognostic index... - A new look at criteria for damage control surgeryHisashi Matsumoto
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School
J Nippon Med Sch 77:13-20. 2010..Such delays could be life-threatening for patients requiring DCS. The aim of this study was to establish simplified and practical criteria to enable rapid decision-making regarding the need for DCS... - [Clinical diagnosis and treatment of pediatric head trauma]Takashi Araki
Division of Neurosurgery, The Hospital for Sick Children
No Shinkei Geka 34:135-46. 2006 - Absence of increased alpha1-microglobulin in IgA nephropathy proteinuriaHiroyuki Yokota
Astellas Pharm Inc, 21 Miyukigaoka, Tsukuba shi 305 8585, Japan
Mol Cell Proteomics 6:738-44. 2007..These results suggest that alpha(1)-microglobulin in IgA nephropathy urine is a characteristic protein and might be a biomarker for IgA nephropathy and that alpha(1)-microglobulin might have a relationship with IgA nephropathy pathology...