Research Topics
| S TakedaSummaryAffiliation: Nippon Medical School Country: Japan Publications
| Collaborators
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Detail Information
Publications
Insertion of the transesophageal echocardiography probe via endoscopy maskToshiya Shiga
Department of Anesthesia, Chiba Hokusoh Hospital, Nippon Medical School, Kamagari 1715, Inba mura, Inba gun, Chiba 270 1694, USA
Anesth Analg 95:561-3, table of contents. 2002..We describe a new technique using an endoscopy mask to perform TEE monitoring during airway manipulation with a large concentration of supplemented oxygen...- Local cardiac wall stabilization influences the reproducibility of regional wall motion during off-pump coronary artery pass surgeryT Shiga
Department of Anesthesiology, Nippon Medical School, Sendagi 1 1 5, Bunkyo ku, Tokyo 113 8603, Japan
J Clin Monit Comput 16:25-31. 2000..quot; This study was designed to investigate whether cardiac wall stabilization with an epicardial stabilizer could affect the interpretation of wall motion during coronary anastomosis without cardiopulmonary bypass... - Patients with diabetic neuropathy are at risk of a greater intraoperative reduction in core temperatureA Kitamura
Department of Anesthesiology, Nippon Medical School Hospital, Tokyo, Japan
Anesthesiology 92:1311-8. 2000..Accordingly, we tested the hypothesis that diabetic patients experience a greater reduction in core temperature during general anesthesia than nondiabetic patients... - Suppression of surgical hyperaldosteronism by potassium canrenoate during gynecologic surgery under sevoflurane anesthesiaT Watanabe
Department of Anesthesiology, Nippon Medical School, Tokyo, Japan
Acta Anaesthesiol Scand 44:758-62. 2000..This study investigated the effect of potassium canrenoate (PC) on pituitary adrenocortical function in lower abdominal surgery under sevoflurane anesthesia... - A prostaglandin E2 receptor subtype EP1 receptor antagonist (ONO-8711) reduces hyperalgesia, allodynia, and c-fos gene expression in rats with chronic nerve constrictionH Kawahara
Department of Anesthesiology, Nippon Medical School, 1 1 5, Sendagi, Bunkyoku, Tokyo, Japan
Anesth Analg 93:1012-7. 2001..The EP1 receptor antagonist significantly reduced hyperalgesia, allodynia, and c-fos positive cells. These findings suggested that EP1 receptor antagonists may have a role in treatment of neuropathic pain... - Survey of observer variation in transesophageal echocardiography: comparison of anesthesiology and cardiology literatureToshiya Shiga
Department of Anesthesia, Chiba Hokusoh Hospital, Nipon Medical School, Chiba, Japan
J Cardiothorac Vasc Anesth 17:430-42. 2003..Thus, a study was conducted systematically reviewing methods reported in transesophageal echocardio graphy articles in peer-reviewed anesthesiology journals versus those reported in peer-reviewed cardiology journals... - Splanchnic organ blood flow during calcitonin gene-related peptide-induced hypotension with or without propranolol in dogsS Takeda
Department of Anesthesiology, Showa University Fujigaoka Hospital, Yokohama, Japan
Anesth Analg 90:1275-80. 2000..These findings suggest that propranolol may impair splanchnic organ blood flow during CGRP-induced hypotension... 
Calibration system for pulse spectrophotometry using a double-layer pulsation flow-cellM Oura
Nihon Kohden Corporation, 1 31 4 Nishi Ochiai, Shinjuku ku, Tokyo, Japan
Conf Proc IEEE Eng Med Biol Soc 2009:896-9. 2009..This system simulates an in vivo environment with high accuracy and enables safe calibration. Consequently, the calibration system is able to standardize the performance and accuracy of pulse photometry...- alpha,alpha-gem-Difluorination of alpha-(alkylthio)acetophenone derivatives with N-fluoropyridinium saltsS Takeda
Central Research Laboratory, SS Pharmaceuticals Co, Ltd, Narita, Chiba, Japan
Chem Pharm Bull (Tokyo) 48:1097-100. 2000..The gem-difluorination reaction using FP-T300 in the presence of zinc bromide was applicable to other alpha-(alkylthio)acetophenone derivatives (1)... - Milrinone improves lung compliance in patients receiving mechanical ventilation for cardiogenic pulmonary edemaS Takeda
Department of Intensive Care Medicine, Nippon Medical School, Tokyo, Japan
Acta Anaesthesiol Scand 47:714-9. 2003..Cardiogenic pulmonary edema is a frequent cause of respiratory failure. We investigated whether milrinone improved lung compliance... - Haemodynamic and splanchnic organ blood-flow responses to hypotension induced by the calcitonin gene-related peptide and sodium nitroprusside in dogsS Takeda
Showa University Fujigaoka Hospital, Department of Anesthesiology, Yokohama, Japan
Eur J Anaesthesiol 19:876-82. 2002.... - Improvement of cardiac fibrosis in dystrophic mice by rAAV9-mediated microdystrophin transductionJ H Shin
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Gene Ther 18:910-9. 2011..These findings indicate that AAV-mediated cardiac transduction with microdystrophin might be a promising therapeutic strategy for the treatment of dystrophin-deficient cardiomyopathy... - Midazolam depresses carotid body chemoreceptor activityC Kim
Department of Anesthesiology, Nippon Medical School, Sendagi, Tokyo, Japan
Acta Anaesthesiol Scand 50:144-9. 2006..We hypothesized that an activation of the carotid body GABA receptors would counteract the depolarizing effect of hypoxia... - Development of cell culture monitoring system and novel non-contact pH measurementM Oura
Nihon Kohden Corporation, Tokyo, Japan
Conf Proc IEEE Eng Med Biol Soc 2011:22-5. 2011..The error was within 0.02; thus, the new pH measurement method is sufficiently accurate for cell culture. This new system is expected to contribute to advances in tissue engineering and regenerative medicine... - Gene therapy for muscular dystrophies: current status and future prospectsS Takeda
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
BioDrugs 15:635-44. 2001..To develop successful treatment of DMD, the authors believe that several different approaches should be used, such as cell transfer therapy, drug design to up-regulate utrophin, or a strategy to repair the mutation in vivo... - Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K/dy3K) miceM Nakagawa
Department of Ultrastructural Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Glia 35:101-10. 2001..This reduction in conduction velocity may be due to small axon diameter, thin myelin sheath and the patchy disruption of the basal lamina of the nodes of Ranvier in dy3K/dy3K mice... - Cilnidipine, the N- and L-type calcium channel antagonist, reduced on 24-h urinary catecholamines and C-peptide in hypertensive non-insulin-dependent diabetes mellitusS Takeda
The First Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
Diabetes Res Clin Pract 44:197-205. 1999..05); 57.6 +/- 7.4 versus 80.6 +/- 8.1 microg/day (P < 0.05), respectively. In conclusion, it was demonstrated that CNP treatment significantly reduced U-NE, U-DA and U-CPR excretion compared with NVP treatment in HT-NIDDM patients... - Effect of postoperative landiolol administration for atrial fibrillation after off pump coronary artery bypass surgeryM Fujii
Department of Cardiovascular Surgery, Nippon Medical School, Tokyo, Japan
J Cardiovasc Surg (Torino) 53:369-74. 2012.... - Haemodynamic and splanchnic organ blood flow responses during sevoflurane-induced hypotension in dogsS Takeda
Showa University Fujigaoka Hospital, Department of Anesthesiology, Yokohama, Japan
Eur J Anaesthesiol 19:442-6. 2002..The aim was to investigate the effects of sevoflurane-induced hypotension on systemic haemodynamics and splanchnic organ blood flows in dogs... - The effect of oral clonidine premedication on lumbar cerebrospinal fluid pressure in humansK Maruyama
Department of Anesthesiology, Nippon Medical School, Tokyo, Japan
J Nippon Med Sch 67:429-33. 2000..619, p=0.019). We conclude that Lumbar CSF pressure was attenuated by oral premedication with 5 microg/kg clonidine. Clonidine also contributed to a significant correlation between preanesthetic mean blood pressure and CSF pressure... - Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene productsK Yuasa
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Gene Ther 14:1249-60. 2007..Our results emphasize the importance to scrutinize the immune responses to AAV vectors in larger animal models before applying rAAV-mediated gene therapy to DMD patients... - Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neuronsW Araki
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, NCNP, Kodaira, Tokyo, Japan
J Neurochem 79:1161-8. 2001..These data collectively suggest that the pro-apoptotic effect of PS2 is mediated by down-regulation of Bcl-2. PS2 mutations may increase the susceptibility of neurons to apoptotic stimuli by perturbing the regulation of cell death... - Development of a compact mock circulation system and a new flow-cell model for pulse spectrophotometryM Oura
Nihon Kohden Corporation, 1 31 4 Nishi Ochiai, Shinjuku ku, Tokyo, Japan
Conf Proc IEEE Eng Med Biol Soc 2008:670-3. 2008..Thus, this system can reduce the time and cost of developing new pulse photometry techniques and other medical equipment... - New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moietyH Eto
Central Research Labs, SS Pharmaceutical Co, Ltd, Narita, Chiba, Japan
Chem Pharm Bull (Tokyo) 49:173-82. 2001..albicans, C. krusei, A. flavus and A. fumigatus in vitro and against C. albicans in vivo for oral and i.v. administrations. Especially, (-)-2a, (-)-2b and (-)-2d showed potent antifungal activities... - Serum androsterone levels in childrenH Ueshiba
First Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan
Horm Metab Res 28:190-2. 1996.... - Cerebral blood oxygenation changes induced by bypass blood flow in moyamoya disease and non-moyamoya cerebral ischaemic diseaseT Hoshino
Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan
Acta Neurochir (Wien) 148:551-7; discussion 557. 2006..Our data suggest that, even if the bypass does not supply blood to the brain during surgery in non-MD, the bypass blood flow gradually increases after surgery...