Yoshinobu Saito

Summary

Affiliation: Nippon Medical School
Country: Japan

Publications

  1. ncbi request reprint Granuloma-forming interstitial pneumonia occurring one year after the start of everolimus therapy
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
    Intern Med 52:263-7. 2013
  2. doi request reprint A case of pneumocystis pneumonia associated with everolimus therapy for renal cell carcinoma
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan, Japan
    Jpn J Clin Oncol 43:559-62. 2013
  3. doi request reprint Current status of DILD in molecular targeted therapies
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Int J Clin Oncol 17:534-41. 2012
  4. ncbi request reprint A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes
    Yoshinobu Saito
    Department of Internal Medicine, Division of Pulmonary Medicine, Nippon Medical School, Tokyo
    Intern Med 46:1739-43. 2007
  5. ncbi request reprint Tiotropium ameliorates symptoms in patients with chronic airway mucus hypersecretion which is resistant to macrolide therapy
    Yoshinobu Saito
    Department of Internal Medicine, Division of Pulmonary Medicine, Nippon Medical School, Tokyo, Japan
    Intern Med 47:585-91. 2008
  6. ncbi request reprint The effects of inhalation of diesel exhaust on murine mycobacterial infection
    Kumiko Hiramatsu
    Fourth Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Exp Lung Res 31:405-15. 2005
  7. doi request reprint Reduction in serum high mobility group box-1 level by polymyxin B-immobilized fiber column in patients with idiopathic pulmonary fibrosis with acute exacerbation
    Shinji Abe
    Department of Pulmonary Medicine Infection and Oncology, Internal Medicine, Nippon Medical School, Tokyo, Japan sabe nms ac jp
    Blood Purif 32:310-6. 2011
  8. doi request reprint Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis
    Minoru Inomata
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Respir Res 15:16. 2014
  9. doi request reprint Fatal pneumonia associated with temozolomide therapy in patients with malignant glioma
    Hiroki Hayashi
    Division of Pulmonary Medicine, Infectious Diseases, and Oncology, Department of Internal Medicine, Nippon Medical School, and Department of Internal Medicine, Heisei Tateisi Hospital, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Jpn J Clin Oncol 42:632-6. 2012
  10. ncbi request reprint [A case of suspected idiopathic pulmonary upper lobe fibrosis (Amitani disease) with acute exacerbation]
    Takahito Nei
    Department of Internal Medicine, Division of Respiratory Medicine, Nippon Medical School
    Nihon Kokyuki Gakkai Zasshi 47:116-21. 2009

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Granuloma-forming interstitial pneumonia occurring one year after the start of everolimus therapy
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan
    Intern Med 52:263-7. 2013
    ..This is a slow-onset case of everolimus-induced ILD in a patient with renal cell carcinoma. Physicians should thus be aware of the potential for the development of ILD at any time during the administration of everolimus therapy...
  2. doi request reprint A case of pneumocystis pneumonia associated with everolimus therapy for renal cell carcinoma
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan, Japan
    Jpn J Clin Oncol 43:559-62. 2013
    ....
  3. doi request reprint Current status of DILD in molecular targeted therapies
    Yoshinobu Saito
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Int J Clin Oncol 17:534-41. 2012
    ..The features of DILD can differ for each drug, and clinicians should thus keep this information about DILD in mind while treating patients...
  4. ncbi request reprint A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes
    Yoshinobu Saito
    Department of Internal Medicine, Division of Pulmonary Medicine, Nippon Medical School, Tokyo
    Intern Med 46:1739-43. 2007
    ..The pneumonitis improved after the cessation of bucillamine. We therefore made a diagnosis of bucillamine-induced interstitial pneumonia. DLST with BAL lymphocytes is thus suggested to be useful for such diagnoses...
  5. ncbi request reprint Tiotropium ameliorates symptoms in patients with chronic airway mucus hypersecretion which is resistant to macrolide therapy
    Yoshinobu Saito
    Department of Internal Medicine, Division of Pulmonary Medicine, Nippon Medical School, Tokyo, Japan
    Intern Med 47:585-91. 2008
    ..There is currently no effective treatment, and an effective therapy is therefore urgently required. The aim of this study was to clarify whether or not the inhalation of tiotropium improves the symptoms in these cases...
  6. ncbi request reprint The effects of inhalation of diesel exhaust on murine mycobacterial infection
    Kumiko Hiramatsu
    Fourth Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Exp Lung Res 31:405-15. 2005
    ..These results indicate that long-term DE exposure may increase pulmonary mycobacterial burden...
  7. doi request reprint Reduction in serum high mobility group box-1 level by polymyxin B-immobilized fiber column in patients with idiopathic pulmonary fibrosis with acute exacerbation
    Shinji Abe
    Department of Pulmonary Medicine Infection and Oncology, Internal Medicine, Nippon Medical School, Tokyo, Japan sabe nms ac jp
    Blood Purif 32:310-6. 2011
    ..This study was aimed to investigate whether PMX treatment affects serum HMGB-1 levels and oxygenation in IPF patients with AE...
  8. doi request reprint Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis
    Minoru Inomata
    Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Respir Res 15:16. 2014
    ..Pirfenidone is an anti-fibrotic agent; however, its effects on fibrocytes have not been investigated. The aim of this study was to investigate whether pirfenidone inhibits fibrocyte pool size in the lungs of bleomycin-treated mice...
  9. doi request reprint Fatal pneumonia associated with temozolomide therapy in patients with malignant glioma
    Hiroki Hayashi
    Division of Pulmonary Medicine, Infectious Diseases, and Oncology, Department of Internal Medicine, Nippon Medical School, and Department of Internal Medicine, Heisei Tateisi Hospital, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Jpn J Clin Oncol 42:632-6. 2012
    ..The patients should also be adequately informed about Pneumocystis pneumonia, and prophylaxis against Pneumocystis pneumonia should be considered proactively before treatment with temozolomide is initiated...
  10. ncbi request reprint [A case of suspected idiopathic pulmonary upper lobe fibrosis (Amitani disease) with acute exacerbation]
    Takahito Nei
    Department of Internal Medicine, Division of Respiratory Medicine, Nippon Medical School
    Nihon Kokyuki Gakkai Zasshi 47:116-21. 2009
    ..We report and discuss this case because there are apparently no previous similar cases...
  11. ncbi request reprint Beneficial effect of polymyxin B-immobilized fiber column (PMX) hemoperfusion treatment on acute exacerbation of idiopathic pulmonary fibrosis
    Yoshitsugu Seo
    4th Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi Bunkyo ku, Tokyo 113 8603, Japan
    Intern Med 45:1033-8. 2006
    ..This study was aimed to investigate the effect of polymyxin B-immobilized fiber column (PMX) hemoperfusion treatment on the acute exacerbation of idiopathic pulmonary fibrosis (IPF)...
  12. ncbi request reprint Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway
    Hajime Takizawa
    Departments of Laboratory Medicine and Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113 8655, Japan
    Am J Physiol Lung Cell Mol Physiol 284:L1055-62. 2003
    ..These findings suggested that DEP stimulated eotaxin gene expression via NF-kappaB-dependent, but STAT6-independent, pathways...
  13. ncbi request reprint Differential secretion of cytokines and adhesion molecules by HUVEC stimulated with low concentrations of bleomycin
    Haruko Miyamoto
    Fourth Department of Internal Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Cell Immunol 219:73-81. 2002
    ..These findings indicate that HUVEC were stimulated to secrete cytokines and express adhesion molecules in the presence of low concentrations of BLM which have a mildly inhibitory effect on cellular proliferation...
  14. ncbi request reprint Long-term inhalation of diesel exhaust affects cytokine expression in murine lung tissues: comparison between low- and high-dose diesel exhaust exposure
    Yoshinobu Saito
    Fourth Department of Internal Medicine, Nippon Medical School, Tokyo, Japan
    Exp Lung Res 28:493-506. 2002
    ..These results suggest that DE alters immunological responses in the lung and may increase susceptibility to pathogens, and that increased IL-4 expression by low-dose DE exposure may induce allergic reaction such as asthma...
  15. ncbi request reprint [Interstitial lung disease associated with chemotherapy and molecularly-targeted drug: diagnosis and management]
    Yoshinobu Saito
    Division of Pulmonary Medicine, Infectious Diseases, and Oncology, Dept of Internal Medicine, Nippon Medical School
    Gan To Kagaku Ryoho 38:2531-7. 2011
    ..However, an exceptional treatment is required for DILD caused by mTOR inhibitor, for which we must take account of the adequate management...