Tsuyoshi Ohmura

Summary

Affiliation: Nippon Boehringer Ingelheim Co
Country: Japan

Publications

  1. ncbi Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys
    T Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim, Japan
    Eur J Pharmacol 378:169-75. 1999
  2. ncbi Role of substance P in an NC/Nga mouse model of atopic dermatitis-like disease
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co Ltd, Kawanishi, Japan
    Int Arch Allergy Immunol 133:389-97. 2004
  3. ncbi Involvement of substance P in scratching behaviour in an atopic dermatitis model
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim, CO, Ltd, 3 10 1 Yato, Kawanishi, 666 0193, Japan
    Eur J Pharmacol 491:191-4. 2004
  4. ncbi Suppression of atopic-like dermatitis by treatment with antibody to lymphocyte function-associated antigen-1 in NC/Nga mouse
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co, Ltd, 3 10 1 Yato, Kawanishi, Japan
    Eur J Pharmacol 504:113-7. 2004
  5. ncbi [Pharmacological and clinical profile of tiotropium bromide (Spiriva), a new long-acting anticholinergic bronchodilator for COPD treatment]
    Tsuyoshi Ohmura
    Nippon Yakurigaku Zasshi 125:307-13. 2005
  6. ncbi Renoprotective effects of telmisartan in the 5/6 nephrectomised rats
    Ichiro Tsunenari
    Pharmacokinetics and Non Clinical Safety Department, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co, Ltd, 3 10 1 Yato, Kawanishi, Japan
    J Renin Angiotensin Aldosterone Syst 8:93-100. 2007
  7. ncbi [Pharmacological and clinical profile of epinastine hydrochloride (Alesion Dry Syrup 1%)]
    Tsuyoshi Ohmura
    Nippon Yakurigaku Zasshi 127:37-46. 2006

Collaborators

Detail Information

Publications7

  1. ncbi Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys
    T Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim, Japan
    Eur J Pharmacol 378:169-75. 1999
    ..Thus, measurement of QTc in cynomolgus monkey appears to be a useful approach for evaluating the potential cardiotoxicity of histamine H1 receptor antagonists...
  2. ncbi Role of substance P in an NC/Nga mouse model of atopic dermatitis-like disease
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co Ltd, Kawanishi, Japan
    Int Arch Allergy Immunol 133:389-97. 2004
    ..Atopic dermatitis (AD) can be exacerbated or induced in genetically predisposed individuals by psychological stress, which causes the release of substance P (SP). Therefore, SP may play an etiological role in the mechanisms underlying AD...
  3. ncbi Involvement of substance P in scratching behaviour in an atopic dermatitis model
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim, CO, Ltd, 3 10 1 Yato, Kawanishi, 666 0193, Japan
    Eur J Pharmacol 491:191-4. 2004
    ..The results suggest that clinical trials of tachykinin NK1 antagonists for the treatment of itching in atopic dermatitis patients would be warranted...
  4. ncbi Suppression of atopic-like dermatitis by treatment with antibody to lymphocyte function-associated antigen-1 in NC/Nga mouse
    Tsuyoshi Ohmura
    Department of Pharmacology, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co, Ltd, 3 10 1 Yato, Kawanishi, Japan
    Eur J Pharmacol 504:113-7. 2004
    ..Our results suggest that LFA-1 plays an important role in the induction phase of the atopic-like dermatitis model...
  5. ncbi [Pharmacological and clinical profile of tiotropium bromide (Spiriva), a new long-acting anticholinergic bronchodilator for COPD treatment]
    Tsuyoshi Ohmura
    Nippon Yakurigaku Zasshi 125:307-13. 2005
  6. ncbi Renoprotective effects of telmisartan in the 5/6 nephrectomised rats
    Ichiro Tsunenari
    Pharmacokinetics and Non Clinical Safety Department, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co, Ltd, 3 10 1 Yato, Kawanishi, Japan
    J Renin Angiotensin Aldosterone Syst 8:93-100. 2007
    ..Thus, telmisartan ameliorates the progressive nephropathy in the remaining kidney after 5/6 Nx by non-haemodynamic as well as antihypertensive actions of the drug...
  7. ncbi [Pharmacological and clinical profile of epinastine hydrochloride (Alesion Dry Syrup 1%)]
    Tsuyoshi Ohmura
    Nippon Yakurigaku Zasshi 127:37-46. 2006