Seiji Kawana

Summary

Affiliation: Nippon Medical School
Country: Japan

Publications

  1. ncbi request reprint Objective evaluation of the effect of intense pulsed light on rosacea and solar lentigines by spectrophotometric analysis of skin color
    Seiji Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Dermatol Surg 33:449-54. 2007
  2. doi request reprint Effect of smooth pulsed light at 400 to 700 and 870 to 1,200 nm for acne vulgaris in Asian skin
    Seiji Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Dermatol Surg 36:52-7. 2010
  3. doi request reprint Efficacy of a 5-HT1a receptor agonist in atopic dermatitis
    S Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Clin Exp Dermatol 35:835-40. 2010
  4. ncbi request reprint Role of substance P in stress-derived degranulation of dermal mast cells in mice
    Seiji Kawana
    Nippon Medical School, Department of Dermatology, 1 1 5 Sendagi, 113 8603 Tokyo, Japan
    J Dermatol Sci 42:47-54. 2006
  5. ncbi request reprint Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non-depilated mouse model
    Mirei Katayama
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Exp Dermatol 16:553-60. 2007
  6. ncbi request reprint Erratum to "changes in cutaneous sensory nerve fibers induced by skin-scratching in mice"
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
    J Dermatol Sci 47:172-82. 2007
  7. ncbi request reprint Dynamic changes in nerve growth factor and substance P in the murine hair cycle induced by depilation
    Zhanchao Zhou
    Department of Dermatology, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    J Dermatol 33:833-41. 2006
  8. ncbi request reprint Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
    J Dermatol Sci 48:123-32. 2007
  9. ncbi request reprint A transient unresponsive state of self-scratching behaviour is induced in mice by skin-scratching stimulation
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, Sendagi, Bunkyo ku, Tokyo, Japan
    Exp Dermatol 16:737-45. 2007
  10. pmc Combined analysis of cell growth and apoptosis-regulating proteins in HPVs associated anogenital tumors
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyou ku, Tokyo, 113 8603, Japan
    BMC Cancer 10:118. 2010

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Objective evaluation of the effect of intense pulsed light on rosacea and solar lentigines by spectrophotometric analysis of skin color
    Seiji Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Dermatol Surg 33:449-54. 2007
    ..To date, intense pulsed light (IPL) has been applied to various skin diseases, but there have been few objective evaluations of its efficacy...
  2. doi request reprint Effect of smooth pulsed light at 400 to 700 and 870 to 1,200 nm for acne vulgaris in Asian skin
    Seiji Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Dermatol Surg 36:52-7. 2010
    ..Intense pulsed light (IPL) treatment is effective for acne in Caucasians, but no significant improvements have been observed in studies on Asian skin...
  3. doi request reprint Efficacy of a 5-HT1a receptor agonist in atopic dermatitis
    S Kawana
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Clin Exp Dermatol 35:835-40. 2010
    ..We recently showed that pretreatment with tandospirone citrate (TC), a serotonin (5-HT) agonist for the 5-HT(1A) receptor subtype, significantly inhibits stress-induced degranulation of mouse dermal mast cells...
  4. ncbi request reprint Role of substance P in stress-derived degranulation of dermal mast cells in mice
    Seiji Kawana
    Nippon Medical School, Department of Dermatology, 1 1 5 Sendagi, 113 8603 Tokyo, Japan
    J Dermatol Sci 42:47-54. 2006
    ..The interaction between nerves and mast cells can effect regulation of the immune system and inflammatory responses. Recent studies have shown that various stressors can induce degranulation of dermal mast cells in animals...
  5. ncbi request reprint Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non-depilated mouse model
    Mirei Katayama
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Exp Dermatol 16:553-60. 2007
    ..Previous studies have shown that stress alters the murine hair cycle; however, these studies have been carried out by using mouse models in which the hair cycle is forcibly synchronized after depilation...
  6. ncbi request reprint Erratum to "changes in cutaneous sensory nerve fibers induced by skin-scratching in mice"
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
    J Dermatol Sci 47:172-82. 2007
    ..Thus, it sometimes exacerbates the original lesions. However, the precise changes that develop in cutaneous sensory nerve fibers after skin-scratching have not yet been elucidated...
  7. ncbi request reprint Dynamic changes in nerve growth factor and substance P in the murine hair cycle induced by depilation
    Zhanchao Zhou
    Department of Dermatology, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    J Dermatol 33:833-41. 2006
    ..NGF may also induce plastic changes such as sprouting and hyperplasia in dermal nerve fibers and enhance their SP production. Elevated levels of SP in skin may additionally contribute to the progression of consecutive anagen hair cycles...
  8. ncbi request reprint Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
    J Dermatol Sci 48:123-32. 2007
    ..Substance P (SP) signaling may play a predominant role in the pathophysiology induced by skin-scratching, however, it has not been well-elucidated...
  9. ncbi request reprint A transient unresponsive state of self-scratching behaviour is induced in mice by skin-scratching stimulation
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, Sendagi, Bunkyo ku, Tokyo, Japan
    Exp Dermatol 16:737-45. 2007
    ..The induction of a transient unresponsive state after skin-scratching may possibly happen also in patients with pruritus. Thus, further studies to elucidate the precise mechanisms are required...
  10. pmc Combined analysis of cell growth and apoptosis-regulating proteins in HPVs associated anogenital tumors
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyou ku, Tokyo, 113 8603, Japan
    BMC Cancer 10:118. 2010
    ..Here we evaluated molecules that are relevant to cellular proliferation and regulation of apoptosis in HPV associated anogenital tumors...
  11. doi request reprint Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study
    Sachiko Kosaka
    Department of Dermatology, Nippon Medical School, Tokyo 113 8603, Japan
    Lasers Surg Med 43:376-81. 2011
    ..The objective of this study was to establish a protocol for ALA-PDT that would provide specific destruction of sebaceous glands at the lowest concentrations and shortest contact times of ALA...
  12. pmc E-cadherin interactions are required for Langerhans cell differentiation
    Nobuko Mayumi
    Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan
    Eur J Immunol 43:270-80. 2013
    ..These findings suggest that E-cadherin expressed by KCs provide environmental cues that induce differentiation of LCs in the epidermis...
  13. doi request reprint Effect of epinastine hydrochloride on murine self-scratching behavior after skin-scratching stimulation
    Halifu Yilinuer
    Department of Dermatology, Nippon Medical School, Sendagi 1 1 5, Bunkyo ku, Tokyo 113 8603, Japan
    Arch Dermatol Res 302:19-26. 2010
    ..These results suggest that second-generation histamine H(1)-receptor antagonists might efficaciously control itch-scratch cycle-related skin diseases...
  14. doi request reprint Specific substance of Maruyama (SSM) suppresses immune responses in atopic dermatitis-like skin lesions in DS-Nh mice by modulating dendritic cell functions
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyou ku, Tokyo 113 8603, Japan
    J Dermatol Sci 63:184-90. 2011
    ..The efficacy of SSM induced interleukin(IL)-12 and IFN-γ production, and inhibition of IL-4, resulting in a shift from Th2 to Th1 in vivo...
  15. doi request reprint Histological evidence for skin rejuvenation using a combination of pneumatic energy, broadband light, and growth factor therapy
    Tokuya Omi
    Department of Dermatology, Queen s Square Medical Center, Yokohama, Japan
    J Cosmet Laser Ther 12:222-6. 2010
    ..This study evaluates the efficacy (at the microscopic level) of a combination of pneumatic energy, broadband light, and profusion tip-delivered epidermal growth factor (EGF)...
  16. doi request reprint Usefulness and pharmacokinetic study of oral terbinafine for hyperkeratotic-type tinea pedis
    Izumi Kikuchi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Mycoses 51:523-31. 2008
    ....
  17. doi request reprint Systemic lupus erythematosus-associated cutaneous cryptococcosis treated successfully with an intermittent 3-day on/off cycle of itraconazole
    Takashi Ueno
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Dermatol 35:778-81. 2008
    ..e. medication on 3 consecutive days and suspension for the next 3 days in turn) achieved complete remission of the cryptococcosis...
  18. doi request reprint Basal cell carcinoma arising on a chronic lymphedematous leg
    Takashi Ueno
    Department of Cutaneous and Mucosal Pathophysiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
    J Dermatol 36:646-8. 2009
    ..However, it remains inconclusive whether or not the tumorigenesis of the BCC was associated with chronic lymphedema in this case...
  19. doi request reprint Ultrastructural evidence for thermal injury to pilosebaceous units during the treatment of acne using photopneumatic (PPX) therapy
    Tokuya Omi
    Department of Dermatology, Queen s Square Medical Center, Yokohama, Japan
    J Cosmet Laser Ther 10:7-11. 2008
    ..This study tested the hypothesis that a combination of pulsed light and suction would affect sebaceous plugging within diseased pilosebaceous apparati at a histological level, resulting in the rapid clearance of acne lesions...
  20. ncbi request reprint Case of Sweet's syndrome with extensive necrosis and ulcers accompanied by myelodysplastic syndrome
    Tokue Kato
    Department of Cutaneous and Mucosal Pathophysiology, Graduate School of Medicine, Nippon Medical School, Sendagi, Bunkyo ku, Tokyo, Japan
    J Nippon Med Sch 75:162-5. 2008
    ..Oral administration of 50 mg/day of prednisolone induced epithelialization of ulcers, with remaining scarring and pigmentation. Six months later, myelodysplastic syndrome had progressed to acute myelogenous leukemia...
  21. ncbi request reprint Intermittent foot shock stress prolongs the telogen stage in the hair cycle of mice
    Eri Aoki
    Department of Dermatology, Nippon Medical School, Tokyo, Japan Department of Physiology, Nippon Medical School, Tokyo, Japan
    Exp Dermatol 12:371-7. 2003
    ..These results suggest that increased levels of plasma corticosterone may be involved in the mechanism underlying the stress-induced delay of the hair cycle...
  22. ncbi request reprint Increased expression of RANTES, CCR3 and CCR5 in the lesional skin of patients with atopic eczema
    Yoko Kato
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Int Arch Allergy Immunol 139:245-57. 2006
    ..Regulated on activation normal T cell expressed and secreted (RANTES/CCL5) is a chemokine that induces eosinophil migration, and CCR3 and CCR5 are the receptors of RANTES...
  23. doi request reprint Clinicopathological significance of sentinel node biopsy in Japanese patients with cutaneous malignant melanoma
    Sachiko Noro
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Dermatol 38:76-83. 2011
    ..0001). Accurate SNB results will provide important prognostic information for Japanese patients with melanoma...
  24. ncbi request reprint Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid
    Yayoi Niimi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Int Arch Allergy Immunol 139:104-13. 2006
    ..Matrix metalloproteinase (MMP)-2, MMP-9 and MMP-13 can degrade type IV collagen which is the major component of the basement membrane zone (BMZ). In bullous pemphigoid (BP), the separation occurs within the BMZ...
  25. doi request reprint Fractional CO2 laser for the treatment of acne scars
    Tokuya Omi
    Department of Dermatology, Queen s Square Medical Center, Yokohama, Japan
    J Cosmet Dermatol 10:294-300. 2011
    ..Numerous reports have been published on skin rejuvenation by the so-called fractional laser device that delivers a laser beam in a dot form over a grid pattern...
  26. ncbi request reprint Bowen's disease with high telomerase activity
    Sachiko Noro
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Dermatol 34:778-81. 2007
    ..In conclusion, some instances of Bowen's disease might have high telomerase activity in the atypical cells and can progress to Bowen's carcinoma. The SNB was regarded as a useful method to detect early lymph node metastases in this case...
  27. ncbi request reprint Human airway trypsin-like protease induces PAR-2-mediated IL-8 release in psoriasis vulgaris
    Kana Iwakiri
    Department of Molecular Pathology, Institute of Gerontology, Graduate School of Medicine, Nippon Medical School, Kawasaki, Japan
    J Invest Dermatol 122:937-44. 2004
    ..Inhibition of PAR-2 resulted in a decreased HAT-induced IL-8 release. Thus, HAT might promote PAR-2-mediated IL-8 production to accumulate inflammatory cells in the epidermal layer of psoriasis...
  28. doi request reprint Effects of stress memory by fear conditioning on nerve-mast cell circuit in skin
    Masayo Kumagai
    Departments of Dermatology, Nippon Medical School, Tokyo, Japan
    J Dermatol 38:553-61. 2011
    ..These findings suggest that prior experience of severe stress linked to a stimulus subsequently evokes fear associated with the same stimulus and results in activation of dermal mast cells and skin nerves...
  29. ncbi request reprint [The effect of suplatast tosilate on the patients with atopic dermatitis--relationship between clinical symptoms and immunological parameters]
    Naoyuki Higashi
    Department of Dermatology, Nippon Medical School
    Arerugi 52:1065-73. 2003
    ..7) There was no sign of adverse effects of the drug. From the above mentioned results, we confirmed the high efficacy of suplatast tosilate in the treatment of atopic dermatitis...
  30. ncbi request reprint Papulonecrotic tuberculid with spontaneous remission
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Dermatol 33:112-4. 2006
    ..Bacterial cultures were not positive from sputum, urine or stool, and the chest X-P was also normal. After skin biopsy, all the lesions disappeared within 1 month. No relapse was noted in the entire body...
  31. doi request reprint Lumican as a novel marker for differential diagnosis of Bowen disease and actinic keratosis
    Ryoko Takayama
    Department of Dermatology Department of Pathology and Department of Integrative Oncological Pathology, Nippon Medical School, Tokyo, Japan
    Am J Dermatopathol 35:827-32. 2013
    ....
  32. ncbi request reprint Identification of 6 sentinel lymph nodes in a case of malignant melanoma on the ungual region of the finger
    Takashi Ueno
    Department of Cutaneous and Mucosal Pathophysiology, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 76:23-6. 2009
    ....
  33. doi request reprint Pigmented poroid neoplasm mimicking nodular melanoma
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, Bunkyou ku, Tokyo, Japan
    J Dermatol 37:542-4. 2010
    ..Immunohistochemistry showed that HMB-45 and Melan-A were positive in malanocytes and melanophages of the pigmented areas. Unlike most poroid neoplasms, this case showed pigmented lesion mimicked nodular melanoma...
  34. doi request reprint Ultrastructural observations of chemical peeling for skin rejuvenation (ultrastructural changes of the skin due to chemical peeling)
    Tokuya Omi
    Department of Dermatology, Queen s Square Medical Center, Yokohama, Japan
    J Cosmet Laser Ther 12:21-4. 2010
    ..These findings suggest that chemical peeling of the skin with this type of agent directly induces collagen formation within the dermis and thus directly stimulates remodeling of the dermis...
  35. ncbi request reprint Prevalence of human papillomavirus DNA sequences in verrucous carcinoma of the lip: genomic and therapeutic approaches
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5, Sendagi, Bunkyou ku, Tokyo 113 8603, Japan
    Cancer Lett 222:139-43. 2005
    ..In addition, the relationship between VC of the lip and HPV infection is discussed, as is therapy against VC...
  36. ncbi request reprint 420 nm intense continuous light therapy for acne
    Tokuya Omi
    Department of Dermatology, Queen s Square Medical Center, Yokohama, Japan
    J Cosmet Laser Ther 6:156-62. 2004
    ..Describe here is a high-intensity, narrow-band, blue light (ClearLight) system, and its therapeutic clinical effect is investigated on acne using cutaneous measurements, bacterial observations and ultrastructural changes...
  37. ncbi request reprint Usefulness and pharmacokinetic study of oral terbinafine for hyperkeratotic type tinea pedis
    Izumi Kikuchi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Mycoses 51:7-13. 2008
    ..These results suggest that TBF is a useful drug to treat hyperkeratotic tinea pedis from the pharmacokinetic point of view...
  38. ncbi request reprint Light-emitting diode phototherapy at 630 +/- 3 nm increases local levels of skin-homing T-cells in human subjects
    Shin Ichiro Takezaki
    Department of Dermatology, Nippon Medical School, Sendagi, Tokyo, Japan
    J Nippon Med Sch 73:75-81. 2006
    ..This study was thus designed to examine changes in skin-homing T-cell levels induced in normal human skin by visible red LED energy...
  39. doi request reprint Combination of carbon dioxide laser therapy and artificial dermis application in plantar warts: human papillomavirus DNA analysis after treatment
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Dermatol Surg 36:1401-5. 2010
    ..Various laser therapies have been used to treat viral warts, and numerous successful results have been reported, but plantar warts are notoriously difficult to treat and eradicate...
  40. ncbi request reprint Clinical significance of blood coagulation factor XIII activity in adult Henoch-Schönlein purpura
    Takemitsu Matayoshi
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 80:268-78. 2013
    ....
  41. doi request reprint Toxic epidermal necrolysis complicated by multiple intestinal ulcers
    Noriyasu Sakai
    Departments of Dermatology and Digestive Medicine, and Center of Emergency Medicine, Nippon Medical School, Tokyo, Japan
    Int J Dermatol 47:180-2. 2008
  42. doi request reprint Nestin is highly expressed in advanced-stage melanomas and neurotized nevi
    Michiko Akiyama
    Department of Pathology, Nippon Medical School, Tokyo 113 8602, Japan
    Oncol Rep 29:1595-9. 2013
    ..Further studies are required to elucidate the regulatory mechanisms of nestin expression and to examine the possibility of nestin-targeted therapy for malignant melanomas...
  43. doi request reprint Ber-EP4 is a useful marker for follicular germinative cell differentiation of cutaneous epithelial neoplasms
    Shin Ichi Ansai
    Department of Dermatology, Nippon Medical School Musashikosugi Hospital, Kawasaki, Japan
    J Dermatol 39:688-92. 2012
    ....
  44. doi request reprint Effect of chemical peeling on the skin in relation to UV irradiation
    Yoko Funasaka
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Exp Dermatol 21:31-5. 2012
    ..It is important to understand the effect of peeling agents on photoaged skin and to know how to deal with UV irradiation during the application of peeling agents and treatment of chemical peeling in daily life...
  45. ncbi request reprint Histological hair removal study by ruby or alexandrite laser with comparative study on the effects of wavelength and fluence
    Tokue Kato
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Cosmet Laser Ther 6:32-7. 2004
    ..Several different laser systems are currently used to remove unwanted hairs. In this study, we studied follicular changes following hair removal with ruby or alexandrite lasers at different fluences...
  46. ncbi request reprint Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma: successful treatment with interferon-alpha
    Takashi Ueno
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Eur J Dermatol 17:539-40. 2007
  47. ncbi request reprint A child with giant cell tumor of tendon sheath
    Takashi Ueno
    Department of Dermatology, Musashi kosugi Hospital, Nippon Medical School, Japan
    Dermatol Online J 17:9. 2011
    ..This report presents the case of a nine-year-old girl with GCTTS arising on her right index finger...
  48. ncbi request reprint A case of hypereosinophilic syndrome
    Akito Amano
    Department of Dermatology, Nippon Medical School, Tokyo 113 8603, Japan
    J Dermatol 32:286-9. 2005
    ..The patient was treated with oral prednisolone at a dose of 60 mg/day, and his cutaneous lesions and other organ symptoms improved...
  49. doi request reprint Case of anaphylaxis due to tetracycline hydrochloride
    Azusa Ogita
    Department of Dermatology, Nippon Medical School Main Hospital, Tokyo, Japan
    J Dermatol 38:597-9. 2011
    ..Prick tests were performed for these suspicious drugs and anaphylaxis due to tetracycline hydrochloride was diagnosed...
  50. ncbi request reprint Changes in cutaneous sensory nerve fibers induced by skin-scratching in mice
    Junichi Yamaoka
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8607, Japan
    J Dermatol Sci 46:41-51. 2007
    ..Thus, it sometimes exacerbates the original lesions. However, the precise changes that develop in cutaneous sensory nerve fibers after skin-scratching have not yet been elucidated...
  51. pmc Divergence of contact hypersensitivity in vivo compared with hapten-specific lymphocyte proliferation and interferon-gamma production in vitro following ultraviolet B irradiation: the possibility that UVB does not affect the sensitizing phase of contact h
    Kayano Suzuki
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Immunology 108:570-8. 2003
    ..Therefore, suppression of the ESR alone cannot always be considered as hapten-specific immunotolerance...
  52. doi request reprint A clinicopathologic study of folliculosebaceous cystic hamartoma
    Shin Ichi Ansai
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Am J Dermatopathol 32:815-20. 2010
    ..All 7 cases showed lesions on face, especially on or around the nose. We consider that Miescher-type melanocytic nevi play a significant role in the pathogenesis of FSCH, at least in some cases...
  53. ncbi request reprint Mechanism of transepithelial elimination of elastic fibers in keratoacanthoma
    Amiko Ohashi
    Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
    Pathol Int 54:585-94. 2004
    ..In that regard, matrix metalloproteinase-1 appears to play a key role in the degradation of collagen fibrils...
  54. ncbi request reprint Urticarial vasculitis appearing in the progression of systemic sclerosis
    Yoko Kato
    Department of Dermatology, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    J Dermatol 33:792-7. 2006
    ..05 and P < 0.005, respectively). We demonstrate that, in the present case, mast cells might be involved in both courses of urticarial vasculitis and systemic sclerosis as a common factor...
  55. doi request reprint Pretibial dystrophic epidermolysis bullosa with localized cutaneous amyloidosis: coincidental or secondary amyloidosis?
    Mikako Aoki
    Department of Dermatology, Nippon Medical School Musashikosugi Hospital, Kawasaki City, Kanagawa, Japan
    J Dermatol 37:259-63. 2010
    ..PDEB, in general, is often misdiagnosed as lichen amyloidosis; however, some PDEB cases could actually be associated with amyloid deposition...
  56. ncbi request reprint Usefulness of itraconazole for sporotrichosis in Japan: study of three cases and literature comparison of therapeutic effects before and after release on the market
    Izumi Kikuchi
    Department of Dermatology, Nippon Medical School, Bunkyo ku, Tokyo 113 8603, Japan
    Eur J Dermatol 16:42-7. 2006
    ..This seems to be attributable to the problem of compliance or the administration method...
  57. ncbi request reprint Corticotropin-releasing factor receptor type 1 is involved in the stress-induced exacerbation of chronic contact dermatitis in rats
    Katsumi Kaneko
    Department of Physiology, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    Exp Dermatol 12:47-52. 2003
    ..These results suggest that CRFR1 is involved in the stress-induced exacerbation of chronic contact dermatitis...
  58. ncbi request reprint A case of peripheral T-cell lymphoma unspecified involving subcutaneous tissue
    Ayako Futagami
    Department of Dermatology, Nippon Medical School, Main Hospital, 1 1 5 Sendagi, Bunkyo ku, Tokyo, Japan
    Leuk Lymphoma 46:785-8. 2005
    ..A genetic analysis demonstrated a rearrangement of the T-cell receptor chain gene. The left skin lesion also gradually disappeared after skin biopsy without therapy, and he continues to be in remission...
  59. ncbi request reprint [Histological changes elicited by hair removal lasers]
    Tokue Kato
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 69:564-70. 2002
    ..The similar influence of each laser treatment resulted in similar histological changes. In this study, the histological changes following treatment with a ruby or an alexandrite laser at the same fluence were considered to be similar...
  60. ncbi request reprint Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES
    Mikako Aoki
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Int Arch Allergy Immunol 130:216-23. 2003
    ..The aim of this study was to elucidate the probable role of mast cells in BCC, especially focusing on the relationship between mast cells and lymphocytic infiltration as well as angiogenesis...
  61. pmc Extraskeletal osteochondroma arising on the plantar region
    Takashi Ueno
    Department of Dermatology, Musashi kosugi Hospital, Nippon Medical School, Kawasaki, Japan
    Case Rep Dermatol 3:147-50. 2011
    ..This report describes the case of a 39-year-old Japanese man with an extraskeletal osteochondroma arising on the plantar aspect of the foot...
  62. ncbi request reprint [Creeping disease]
    Yayoi Niimi
    Department of Dermatology, Nippon Medical School
    J Nippon Med Sch 70:206-7. 2003
  63. ncbi request reprint Folliculosebaceous cystic hamartoma with hair shaft fragments
    Kenji Yamagata
    Department of Dermatology, Nippon Medical School, 1 1 5 Sendagi, Bunkyou ku, Tokyo 113 8603, Japan
    Eur J Dermatol 15:105-6. 2005
    ..To our knowledge, this case is unusual with the presence of hair shaft fragments within the cystic structure. In addition, we discuss the histopathological findings of FCH and also review other cases of FCH in the literature...
  64. doi request reprint Case of livedoid vasculopathy with peripheral neuropathy successfully treated with low-dose warfarin
    Shin Ichi Osada
    Department of Dermatology, Nippon Medical School, Tokyo 113 8602, Japan
    J Dermatol 37:98-101. 2010
    ..This case suggests that administration of low-dose warfarin is an effective therapy of choice for patients with livedoid vasculopathy...
  65. ncbi request reprint Cimetidine treatment for viral warts enhances IL-2 and IFN-gamma expression but not IL-18 expression in lesional skin
    Tsuyoshi Mitsuishi
    Department of Dermatology, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Eur J Dermatol 13:445-8. 2003
    ..These results suggest that cimetidine is an effective treatment for viral warts. In addition, based on the decrease in IL-18 mRNA elicited by the drug, IL-18 might be expressed by keratinocytes infected with HPV...
  66. doi request reprint Sebaceous carcinoma: an immunohistochemical reappraisal
    Shin Ichi Ansai
    Department of Dermatology, Nippon Medical School, Tokyo, Japan
    Am J Dermatopathol 33:579-87. 2011
    ..The detection of AR and ADP was useful for differentiating SC from SCC, whereas the determination of EMA, CA15-3, Ber-EP4, and ADP was valuable in differentiating SC from BCC...
  67. doi request reprint Type 2 segmental manifestation of disseminated superficial actinic porokeratosis in a 7-year-old girl
    Yayoi Niimi
    Department of Dermatology, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    Eur J Dermatol 19:25-8. 2009
    ..The combination of different types of porokeratosis in one individual is rare. We consider that this case may represent a type 2 segmental manifestation of disseminated superficial actinic porokeratosis...
  68. doi request reprint Case of anaphylaxis caused by ingestion of royal jelly
    Mirei Katayama
    Department of Dermatology, Nippon Medical School, Musashikosugi Hospital, 1 396 Kosugi chou, Nakahara ku, Kanagawa, Japan
    J Dermatol 35:222-4. 2008
    ..Increased consumption of royal jelly in health food supplements may increase the incidence of royal jelly-related allergic reactions. Therefore, royal jelly should be considered as a causative allergen in food-induced anaphylaxis...