Research Topics
| T AraiSummaryAffiliation: Nippon Veterinary and Animal Science University Country: Japan Publications
| Collaborators
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Detail Information
Publications
Increased serum and urinary neopterin in nephrotic syndrome indicate cell-mediated immune dysfunctionK Oda
Department of Internal Medicine, Teikyo University School of Medicine, 11 1, Kaga, 2 chome, Itabashi ku, Tokyo, 173 8605, Japan
Am J Kidney Dis 34:611-7. 1999..Increased serum NP concentrations and urinary NP/Cr ratios may reflect disordered cell-mediated immunity in the nephrotic syndrome, irrespective of glomerular histology or interstitial cell infiltration...- Decrease in malate dehydrogenase activities in peripheral leucocytes of type 1 diabetic dogsT Arai
Department of Veterinary Science, Nippon Veterinary and Animal Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 74:183-5. 2003..The decrease of the M/L ratio appeared to reflect depression of energy metabolism in leucocytes of the diabetic dogs. The M/L ratio may be a useful parameter to evaluate metabolic conditions in diabetic dogs... - Activities of enzymes in the malate-aspartate shuttle and the isoenzyme pattern of lactate dehydrogenase in plasma and peripheral leukocytes of lactating Holstein cows and riding horsesT Arai
Divisions of Veterinary Biochemistry, Department of Veterinary Science, Nippon Veterinary and Animal Science University, Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 75:15-9. 2003..There were significant differences in activities of malate-aspartate shuttle enzymes, ML ratio and LDH isoenzyme patterns in the cytosolic fractions of leukocytes between the lactating cows and the riding horses... - Malate dehydrogenase activities are lower in some types of peripheral leucocytes of dogs and cats with type 1 diabetes mellitusE Magori
Division of Veterinary Biochemistry, Department of Veterinary Science, Nippon Veterinary and Animal Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
Res Vet Sci 78:39-44. 2005..The smaller M / L ratio appeared to reflect depression of energy metabolism in the diabetic animals. Intrinsically lower and further decreased MDH activities may be factors that induce insulin resistance observed in diabetic cats... 
Time-action profiles of insulin detemir in normal and diabetic dogsT Sako
Department of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 90:396-403. 2011..However, using insulin detemir also carries a higher risk of inducing hypoglycemia as compared to either NPH insulin or insulin glargine...- Changes in peripheral leukocytes enzymes activity and plasma metabolite concentrations in growing Holstein calvesT Arai
Department of Veterinary Science, Nippon Veterinary and Animal Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 81:19-23. 2006..Some peripheral leukocyte enzymes such as LDH and HK may be good indicators to evaluate changes in energy metabolism of growing calves... - Changes in activities of enzymes related to energy metabolism in testicular tissues of dogs with seminomaT Arai
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
Vet Res Commun 26:347-52. 2002..These enzymatic activities may be useful indicators with which to evaluate changes in the metabolic conditions in testicular tissues of dogs with seminoma... - Changes in activities of enzymes related to energy metabolism in peripheral leukocytes of diabetic dogs with glycemic control by intensive insulin treatmentT Arai
Division of Veterinary Biochemistry, Department of Veterinary Science, Nippon Veterinary and Animal Science University, Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 73:183-6. 2002.... - Activities of enzymes in the malate-aspartate shuttle in the peripheral leukocytes of dogs and catsT Washizu
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
Vet Res Commun 25:623-9. 2001..High activities of MDH in canine leukocytes were confirmed by RT-PCR analysis on the total RNA extracted from leukocytes. It was concluded that there were significant differences between dogs and cats in the NADH shuttle system... - Comparison of plasma metabolite concentrations and lactate dehydrogenase activity in dogs, cats, horses, cattle and sheepT Sako
Department of Veterinary Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
Vet Res Commun 31:413-7. 2007 - Hypertriglyceridemia with increased plasma insulin concentrations in catsY Hatano
School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 88:458-60. 2010..Increased TG, insulin, LDH and ALT and decreased adiponectin values in plasma seemed to be key factors for diagnosis of lipid metabolism abnormality at early stage in cats... - Comparison of activities of enzymes related to energy metabolism in peripheral leukocytes and livers between Holstein dairy cows and ICR miceA Tanaka
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo 180-8602, Japan
Vet Res Commun 30:29-38. 2006..The LDH isoenzyme patterns were very similar between leukocytes and liver in each animal species. Some enzymes in leukocytes may reflect those enzymes activities in liver and be a useful indicator for energy metabolism in animals... - Changes in activities of enzymes related to malate-aspartate shuttle in leukocytes from dogs given a herb supplementT Arai
Division of Veterinary Biochemistry, Nippon Veterinary and Animal Science University, Tokyo, Japan
J Vet Med Sci 63:695-7. 2001..It is suggested that Echevaria glauca herb supplementation might activate NADH shuttle systems and mitochondrial energy metabolism in dogs... - Comparison of plasma metabolite concentrations and peripheral leukocyte enzyme activities in sheep fed on different diets in New Zealand and JapanT Arai
Department of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo
Vet Res Commun 31:681-4. 2007 - Enzyme activities in some types of peripheral leukocytes of thoroughbred race horses before and after the racesM Hosoya
Division of Veterinary Biochemistry, Department of Veterinary Science, Nippon Veterinary and Animal Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
Res Vet Sci 77:101-4. 2004..The cytosolic ratio of MDH/LDH activity (ML ratio) in leukocytes decreased significantly after racing, and the ratio may be a useful indicator to evaluate energy metabolism in race horses... - Comparison of three commercially available prescription diet regimens on short-term post-prandial serum glucose and insulin concentrations in healthy catsA Mori
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo, 180 8602, Japan
Vet Res Commun 33:669-80. 2009..As such, having a better understanding for each dietary component, may lead us to better understand how we can synergize certain dietary components to aid in DM management... - Comparison of insulin signaling gene expression in insulin sensitive tissues between cats and dogsA Mori
Department of Veterinary Science, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo, 180 8602, Japan
Vet Res Commun 33:211-26. 2009..Therefore, a combination of genetic and environmental factors appears to make felines more prone to suffer from insulin resistance and type 2 DM than canines... - Plasma metabolite concentrations and hepatic enzyme activities in pregnant Romney ewes with restricted feedingY Tanaka
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 85:17-21. 2008..Restricted feeding could maintain pregnancy and some plasma metabolites and peripheral leukocyte enzymes may be useful indicators for evaluating metabolic changes in ewes... - Predisposition for primary hyperlipidemia in Miniature Schnauzers and Shetland sheepdogs as compared to other canine breedsN Mori
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 88:394-9. 2010..Gender differences were also observed with regards to severity. In fact, a higher severity was prevalent with female Miniature Schnauzers than their male counterparts whereas it was more balanced between genders for Shetland sheepdogs... - Activities of enzymes related to the malate-aspartate shuttle in the blood cells of thoroughbred horses undergoing training exerciseT Arai
Division of Veterinary Biochemistry, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
Vet Res Commun 25:577-83. 2001..This increase in the MDH activity in their WBC is considered to reflect the increased metabolic activity in the race horses resulting from the training... - Clinical significance of plasma mannose concentrations in healthy and diabetic dogsA Mori
Department of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, 180 8602, Japan
Vet Res Commun 33:439-51. 2009..Therefore, plasma mannose levels obtained via glucose tolerance testing may be used as a new diagnostic method for evaluating insulin resistance or deficiency in diabetic dogs... - Comparison of plasma metabolite concentrations and enzyme activities in beef cattle raised by different feeding systems in Korea, Japan and New ZealandA Mori
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashiro, Tokyo 180 8602, Japan
J Vet Med A Physiol Pathol Clin Med 54:342-5. 2007..Plasma metabolite concentrations and energy metabolism-related enzyme activities may be good indicators for evaluating metabolic conditions of beef cattle raised by different feeding systems... - Obesity induced changes to plasma adiponectin concentration and cholesterol lipoprotein composition profile in catsS Muranaka
School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 91:358-61. 2011..05) in LDL-cholesterol % as compared to age matched healthy control animals. This would indicate that changes in plasma adiponectin concentration and cholesterol lipoprotein composition may be good early indicators of obesity in cats... - Changes in activities of enzymes related to energy metabolism in peripheral leukocytes of fattening steersN Kimura
Division of Animal Nutrition, Department of Animal Science, Nippon Veterinary and Animal Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan
Vet Res Commun 29:19-26. 2005..The cytosolic ratio of MDH/lactate dehydrogenase (LDH) activity in leukocytes increased significantly in the fattening process and was considered to be a useful indicator for evaluating changes in energy metabolism in steers... - Changes in metabolite, energy metabolism related enzyme activities and peripheral blood mononuclear cell (PBMC) populations in beef heifers with two differing liveweight change profiles in New ZealandA Mori
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Vet Res Commun 32:159-66. 2008..Plasma IRI and FFA concentrations, leukocyte cytosolic and mitochondrial MDH activities and CD3 positive and NK cell populations may be useful markers to evaluate metabolic conditions and immunity in the restricted feeding beef heifers... - Cytosolic ratio of malate dehyrogenase/lactate dehydrogenase activity in peripheral leukocytes of race horses with trainingT Arai
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 72:241-4. 2002..Increase in the M/L ratio was considered to reflect elevation of energy metabolism in animal tissues. The M/L ratio may be a useful parameter to evaluate the difference in metabolic states between race horses and riding horses... - Activities of enzymes in some types of peripheral leucocytes may reflect the differences in nutrient metabolism between dogs and catsA Takeguchi
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Kyonancho, Musashino, Tokyo 180-8602, Japan
Res Vet Sci 78:21-4. 2005..Higher activities of FK, PK and G6PD, which regulate the rate of biosynthesis of fatty acids, may reflect the different characteristics in nutrient metabolism in feline tissues from canine tissues... - Plasma glucose, mannose, and non-esterified fatty acid concentrations in layer-type chickensT Sato
Faculty of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
Br Poult Sci 49:731-5. 2008..3. At the age of 18 and 150 d, plasma glucose concentrations were elevated and plasma mannose and NEFA concentrations were decreased after regular feeding, compared to fasting levels... - Assessing the immune state of dogs suffering from pituitary gland dependent hyperadrenocorticism by determining changes in peripheral lymphocyte subsetsA Mori
Department of Veterinary Science, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo, 180 8602, Japan
Vet Res Commun 33:757-69. 2009..PDH dogs may be suffering from an immuno-depressed state as evidenced by significant differences in lymphocyte subset populations. Furthermore, treatment of both PDH and concurrent disease might improve lymphocyte subset distribution... - Comparison of time-action profiles of insulin glargine and NPH insulin in normal and diabetic dogsA Mori
Department of Veterinary Science, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Vet Res Commun 32:563-73. 2008..However, co-administration result in hypoglycemia at the dosages tested... - The activity ratio of the cytosolic MDH/LDH and the isoenzyme pattern of LDH in the peripheral leukocytes of dogs, cats and rabbitsT Washizu
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
Vet Res Commun 26:341-6. 2002..LDH-1 and LDH-2 were dominant in rabbit leukocytes, whereas LDH-5 was dominant in feline leukocytes. It was evident that there were significant differences in energy metabolism between the leukocytes of dogs, rabbits and cats... - Effect of glimepiride and nateglinide on serum insulin and glucose concentration in healthy catsA Mori
School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Vet Res Commun 33:957-70. 2009..These findings may provide useful information when choosing a hypoglycemic drug suited for the treatment of diabetic cats depending on the degree of diabetes mellitus the cat is suffering from... - The pathological characteristics of acute antibody-mediated rejection in DA-to-Lewis rat orthotopic liver transplantationS Kunugi
Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
Transplant Proc 43:2737-40. 2011.... - Decreased gene expression of insulin signaling genes in insulin sensitive tissues of obese catsA Mori
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1, 7, 1 Kyonancho, Musashino, Tokyo, Japan
Vet Res Commun 33:315-29. 2009..As such, the monitoring of key insulin signaling genes may have some important diagnostic value to determine the risk level and degree of obesity induced insulin resistance... - Effects of metformin on plasma concentrations of glucose and mannose, G6Pase and PEPCK activity, and mRNA expression in the liver and kidney of chickensT Sato
School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Br Poult Sci 52:273-7. 2011..In contrast, no suppression of enzyme activity or mRNA expression was observed in chicken liver. Therefore, the mode of action of metformin, via AMPK activation, may be different in the chicken liver... - Effect of supplementation of Agaricus mushroom meal extracts on enzyme activities in peripheral leukocytes of calvesN Kimura
Division of Animal Nutrition, Department of Animal Science, Nippon Veterinary and Animals Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 82:7-10. 2007..blazei. It was concluded that supplementation of Agaricus mushroom meal extract was effective in activation of enzymes related to energy metabolism in peripheral leukocytes of calves... - Serum glycated albumin: Potential use as an index of glycemic control in diabetic dogsT Sako
Department of Veterinary Nursing, Nippon Veterinary and Life Science University, Musashino, Tokyo, 180 8602, Japan
Vet Res Commun 33:473-9. 2009..Furthermore, serum GA% can reflect long-term changes (almost 1-3 weeks) in blood glucose concentration and the effect of injected insulin in diabetic dogs... - Comparison of expression of glucokinase gene and activities of enzymes related to glucose metabolism in livers between dog and catA Tanaka
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo 180-8602, Japan
Vet Res Commun 29:477-85. 2005..Expression of GK gene was observed in canine liver and pancreas and feline pancreas with RT-PCR using species specific primers based on the cDNA sequences... - Non-targeted analyses of animal plasma: betaine and choline represent the nutritional and metabolic statusK Katayama
School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1 7 1 Kyonan cho, Musashino shi, Tokyo, Japan
J Anim Physiol Anim Nutr (Berl) 97:119-25. 2013..The metabolite was identified as betaine by LC-MS/MS. This result indicates that betaine and its metabolic precursor, choline, may be useful biomarkers to evaluate the nutritional and metabolic status of animals... - Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient miceT Arai
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, 180 8602, Japan
Clin Exp Med 8:93-9. 2008..IRS2-deficient mice may be a useful animal model for studying the degradation mechanism of pancreatic beta cells in the process of development of fulminant type 1 DM... - Simultaneous determination of serum mannose and glucose concentrations in dog serum using high performance liquid chromatographyT Sato
Department of Veterinary Science, School of Veterinary Medicine, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Res Vet Sci 84:26-9. 2008..This HPLC method may be useful for determination of monosaccharides in animal blood... - [Lymph node metastasis in superficial squamous carcinoma of the esophagus]K Takubo
Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, and Department of Pathology, Tokyo Metropolitan Geriatric Medical Center, Tokyo, Japan
Pathologe 34:148-54. 2013.... - Aldehyde dehydrogenase activity in cancer stem cells from canine mammary carcinoma cell linesM Michishita
Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1 7 1 Kyonan cho, Musashino, Tokyo 180 8602, Japan
Vet J 193:508-13. 2012..ALDH(high)-derived tumours contained both ALDH(+) and ALDH(-) cells, indicating that these cells had cancer stem cell-like properties... - Japanese encephalitis - serial CT findings and neuropathology in an autopsy caseZ Kobayashi
Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Clin Neuropathol 28:422-9. 2009..We discussed for the first time the correlation of CT and neuropathological findings in a patient with Japanese encephalitis... - Effect of herb supplement on hepatic enzyme activities in ddY miceT Arai
Department of Veterinary Science, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
Lab Anim 35:288-91. 2001..It was found that dietary herb supplement caused an acceleration of hepatic function, judged by increased activities of glycolytic enzyme and GSHpx in ddY mice... - Three-dimensional organization of the hepatic microvasculature in hereditary hemorrhagic telangiectasiaM Sawabe
Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan
Arch Pathol Lab Med 125:1219-23. 2001..The 3-dimensional reconstruction study of hepatic microvasculature was successful in identifying the pathological changes responsible for the intrahepatic shunts in HHT... - Correlation of telomere lengths in normal and cancers tissue in the large bowelK Nakamura
Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology, 32 5, Sakaecho Itabashi ku, 173 0015, Tokyo, Japan
Cancer Lett 158:179-84. 2000..Straight, essentially parallel, lines were obtained for the two cases, normal tissue values being about 2 kilobase pairs (kbp) higher, with a significant correlation between data at the individual patient level... - Age-related hypermethylation of the hMLH1 promoter in gastric cancersT Nakajima
Department of Molecular Oncology, Tokyo Medical and Dental University, Tokyo, Japan
Int J Cancer 94:208-11. 2001..The frequency of hMLH1 methylation significantly increased with age. These results suggest that hMLH1 methylation plays an important role in gastric carcinogenesis in old people... - Early squamous cell carcinoma of the oesophagus: the Japanese viewpointK Takubo
Research Team for Geriatric Diseases, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
Histopathology 51:733-42. 2007..As a result of advances in the development of endoscopes, pathologists are now expected to diagnose very minute lesions, < 1 mm in size, in the oesophagus... - Biological characteristics and chemosensitivity profile of four human anaplastic thyroid carcinoma cell linesM Sekiguchi
EIectro Chemical and Cancer Institute, Chofu, Tokyo, Japan
Biomed Pharmacother 55:466-74. 2001..This finding indicates that the multidrug resistance of these lines is mediated by a P-glycoprotein-unrelated mechanism. The RT-PCR also presented FAS mRNA in all the lines, and IL-6 and IL-8 mRNAs in some of the lines... - Lymphangiogenesis associated with acute cellular rejection in rat liver transplantationE Ishii
Department of Analytic Human Pathlogy, Nippon Medical School, Tokyo, Japan
Transplant Proc 42:4282-5. 2010..It may be involved in the resolution of ACR and reduction of inflammation. In severe ACR and AMR, lymphatic vessels were destroyed, which may be involved in persistent severe inflammation... - Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synucleinT Arai
Department of Neuropathology, Institute of Psychiatry, Tokyo, Japan
Neurosci Lett 259:83-6. 1999.... - The muscles of mastication in the caspian seal (Phoca caspica)H Endo
Department of Zoology, National Science Museum, Tokyo, Japan
Anat Histol Embryol 31:262-5. 2002.... - Expression of a neutrophil chemotactic protein LECT2 in human hepatocytes revealed by immunochemical studies using polyclonal and monoclonal antibodies to a recombinant LECT2S Yamagoe
Department of Bioactive Molecules, National Institute of Infectious Diseases, Tokyo, Japan
Biochem Biophys Res Commun 237:116-20. 1997..These results indicated that the novel protein was expressed in hepatocytes and suggested an important role of LECT2 in the cells in addition to the activation of neutrophils... - Implantation of primary cultured adipocytes that secrete insulin modifies blood glucose levels in diabetic miceM Ito
Department of Genome Research and Clinical Application, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba 260-8670, Japan
Diabetologia 48:1614-20. 2005..CONCLUSIONS/INTERPRETATION: These results indicate that the autotransplantation of functionalised adipocytes may lead to a clinical application in the treatment of diabetes... - Induction of drug metabolism-related enzymes by methylcholanthrene and phenobarbital in transgenic mice carrying human prototype c-Ha-ras gene and their wild type littermatesY Ohnishi
Central Institute for Experimental Animals, 1430 Nogawa, Miyamae ku, Kawasaki shi 216 0001, Japan
Exp Anim 50:33-9. 2001..These results suggest that the human c-Ha-ras transgene may not affect drug metabolism-related enzymes, and the facilitated carcinogenic response in the Tg-rasH2 mouse is not due to these enzymatic disorders... - Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1D Huszar
Millennium Pharmaceuticals, Inc, Cambridge, MA 02139, USA
Arterioscler Thromb Vasc Biol 20:1068-73. 2000..These findings suggest that upregulation of the receptor could have therapeutic potential for the treatment of atherosclerosis... - Roles of the transmembrane domain and the cytoplasmic domain of Fc epsilon RI alpha in immunoglobulin E-mediated up-regulation of surface Fc epsilon RI expressionY Okayama
Research Unit for Allergy Transcriptome, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Japan
Clin Exp Allergy 37:451-8. 2007..IgE up-regulates Fc epsilon RI alpha expression, but IgG1 does not up-regulate Fc gamma RI alpha expression. The transmembrane domain (TM) of Fc gamma RI alpha determines the stability of cell surface expression of this receptor... - The effects of a high-carbohydrate diet on the stress-strain behavior of the periodontal ligament of the distal root of the mandibular first molar in hamstersY Yamazaki
Department of Periodontics and Endodontics, School of Dental Medicine, Tsurumi University, Yokohama, Japan
J Periodontal Res 36:301-8. 2001.... - Purification of a new extracellular 90-kDa serine proteinase with isoelectric point of 3.9 from Bacillus subtilis (natto) and elucidation of its distinct mode of actionT Kato
Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan
Biosci Biotechnol Biochem 56:1166-8. 1992..The activity was inhibited by phenylmethylsulfonyl fluoride (PMSF) and chymostatin, while the activity was not inhibited by proteinaceous Streptomyces subtilisin inhibitor (SSI) or alpha 2-macroglubulin... - Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned ratsT Funahashi
Second Department of Internal Medicine, Osaka University, Medical School, Japan
Biochem Biophys Res Commun 211:469-75. 1995..These data suggest that ob gene might be up-regulated with fat accumulation even in non-genetically obese animals... - Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cellsJ Ohuchi
Laboratory of Experimental Animal Science, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060 0818, Japan
Mol Reprod Dev 59:350-8. 2001..We are proposing the name, sperm-tail-associated protein (Stap), for the gene encoding F77 cDNA. Mol. Reprod. Dev. 59: 350-358, 2001... - The cloning and nucleotide sequence of human ST2L cDNAH Li
Department of Biochemistry, Jichi Medical School, Tochigi, Japan
Genomics 67:284-90. 2000..We also established stable transfectants of a human glioblastoma cell line, T98G, that express human ST2L constitutively, and we confirmed cell-surface expression of human ST2L protein on the transfectants... - The 17-kDa sheath protein in enamel proteins induces cementum regeneration in experimental cavities created in a buccal dehiscence model of dogsM Kanazashi
Department of Periodontics and Endodontics, School of Dental Medicine, Tsurumi University, Yokohama, Japan
J Periodontal Res 41:193-9. 2006..The purpose of this in vivo study was to identify the cementum regeneration-promoting factor in enamel proteins that is clinically used for periodontal regeneration to induce cementum-promotive and osteopromotive activities...