Hirohisa Yoshizawa

Summary

Affiliation: Niigata University
Country: Japan

Publications

  1. ncbi request reprint Cancer immunogene therapy
    H Yoshizawa
    Department of Medicine II, Niigata University Medical School, Japan
    Arch Immunol Ther Exp (Warsz) 49:337-43. 2001
  2. pmc Phase I/II study of daily carboplatin, 5-fluorouracil and concurrent radiation therapy for locally advanced non-small-cell lung cancer
    H Yoshizawa
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951 8510, Japan
    Br J Cancer 89:803-7. 2003
  3. pmc Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis
    Satoshi Watanabe
    Department of Medicine, Niigata University Medical and Dental Hospital, Niigata City, Japan
    BMC Cancer 11:1. 2011
  4. doi request reprint Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity
    Kosuke Ichikawa
    Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Japan
    Vaccine 30:6190-7. 2012
  5. ncbi request reprint Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression
    Toru Hiura
    Graduate School of Medical and Dental Sciences, Course for Biological Functions and Medical Control, Department of Homeostatic Regulation and Development, Division of Respiratory Medicine, Niigata University, Niigata, Japan
    J Immunol 175:5058-66. 2005
  6. doi request reprint Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage
    Kenichi Koyama
    Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Clin Cancer Res 14:6770-9. 2008
  7. ncbi request reprint [A case of recurrent pulmonary lymphoepithelioma-like carcinoma responding to treatment with CBDCA/paclitaxel combined chemotherapy]
    Tetsuya Abe
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
    Gan To Kagaku Ryoho 31:1215-7. 2004
  8. ncbi request reprint Depletion of radio-resistant regulatory T cells enhances antitumor immunity during recovery from lymphopenia
    Junko Baba
    Department of Medicine II, Niigata University Medical and Dental Hospital, Niigata City, Niigata, Japan
    Blood 120:2417-27. 2012
  9. ncbi request reprint Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer
    Yoshiki Hayashi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Intern Med 48:203-8. 2009
  10. ncbi request reprint Facial axis angle as a risk factor for obstructive sleep apnea
    Yukiko Kubota
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Intern Med 44:805-10. 2005

Collaborators

  • Hiroshi Tanaka
  • Koh Nakata
  • Eiichi Suzuki
  • F Gejyo
  • Osamu Kobayashi
  • Rie Kondo
  • K Ito
  • Y Maruyama
  • Takashi Ishida
  • T Sato
  • J Tanaka
  • Takashi Hasegawa
  • Tetsuya Abe
  • Hiroshi Kagamu
  • Satoshi Watanabe
  • Ichiei Narita
  • Satoru Miura
  • Kosuke Ichikawa
  • Takao Miyabayashi
  • Junko Baba
  • Jun Koshio
  • Kenichi Koyama
  • Toru Hiura
  • Daiki Mifune
  • Yoshiki Hayashi
  • Hideyuki Kuriyama
  • Yukiko Kubota
  • Makoto Satoh
  • Kunihiko Sakai
  • Hideaki Nakayama
  • Shin ichi Kinebuchi
  • Hiromi Miyao
  • Masaaki Okajima
  • Kazuhiro Sato
  • Akira Iwashima
  • Akira Yokoyama
  • Masato Makino
  • Tomohiro Tanaka
  • Katsuya Deguchi
  • Koichiro Nozaki
  • Chunrui Tan
  • Toshiyuki Koya
  • Yu Saida
  • Takafumi Tetsuka
  • Yoko Wada
  • Takeshi Ota
  • Asako Matsuyama
  • Hiroshi Moriyama
  • Hajime Umezu
  • Tatsuya Yoshimasu
  • Tomoko Furukawa
  • Takahiro Miyabayashi
  • Ryo Itoh
  • Akira Ishida
  • Kohei Akazawa
  • Masami Nakamata
  • Toshinori Takada
  • Naho Matsuyama
  • Junichiro J Kazama
  • Nanae Fujita

Detail Information

Publications16

  1. ncbi request reprint Cancer immunogene therapy
    H Yoshizawa
    Department of Medicine II, Niigata University Medical School, Japan
    Arch Immunol Ther Exp (Warsz) 49:337-43. 2001
    ..In this review, recent progress in cancer immunogene therapy is discussed...
  2. pmc Phase I/II study of daily carboplatin, 5-fluorouracil and concurrent radiation therapy for locally advanced non-small-cell lung cancer
    H Yoshizawa
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951 8510, Japan
    Br J Cancer 89:803-7. 2003
    ..The major toxicities of treatment were neutropenia (>or=grade 3, 87.9%) and thrombocytopenia (>or=grade 3, 23.3%). This combined therapy for locally advanced non-small-cell lung cancer is promising and shows acceptable toxicity...
  3. pmc Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis
    Satoshi Watanabe
    Department of Medicine, Niigata University Medical and Dental Hospital, Niigata City, Japan
    BMC Cancer 11:1. 2011
    ..The present study was conducted to evaluate the efficacy and toxicity of the 2(nd) EGFR-TKI administration...
  4. doi request reprint Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity
    Kosuke Ichikawa
    Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Japan
    Vaccine 30:6190-7. 2012
    ..Notably, this immunotherapy did not require pretreatment to reduce Treg induced by tumor. This strategy may have clinical implications for designing effective antitumor immunotherapies...
  5. ncbi request reprint Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression
    Toru Hiura
    Graduate School of Medical and Dental Sciences, Course for Biological Functions and Medical Control, Department of Homeostatic Regulation and Development, Division of Respiratory Medicine, Niigata University, Niigata, Japan
    J Immunol 175:5058-66. 2005
    ..CD62L(high)CD4(+)CD25(+) Treg contained a subpopulation that expressed CD86. Blocking experiments revealed that ligation of CTLA-4 on effector T cells by CD86 on Treg plays a pivotal role in regulating CD4(+) effector T cells...
  6. doi request reprint Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage
    Kenichi Koyama
    Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Clin Cancer Res 14:6770-9. 2008
    ..The purpose of this study was to elucidate the immunologic balance induced in SCLC patients...
  7. ncbi request reprint [A case of recurrent pulmonary lymphoepithelioma-like carcinoma responding to treatment with CBDCA/paclitaxel combined chemotherapy]
    Tetsuya Abe
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
    Gan To Kagaku Ryoho 31:1215-7. 2004
    ..CBDCA/PTX combined chemotherapy is effective for pulmonary lymphoepithelioma-like carcinoma and shows good tolerability and improves QOL...
  8. ncbi request reprint Depletion of radio-resistant regulatory T cells enhances antitumor immunity during recovery from lymphopenia
    Junko Baba
    Department of Medicine II, Niigata University Medical and Dental Hospital, Niigata City, Niigata, Japan
    Blood 120:2417-27. 2012
    ....
  9. ncbi request reprint Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer
    Yoshiki Hayashi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Intern Med 48:203-8. 2009
    ....
  10. ncbi request reprint Facial axis angle as a risk factor for obstructive sleep apnea
    Yukiko Kubota
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Intern Med 44:805-10. 2005
    ..The purpose of this study was to identify bony factors associated with OSA in the Japanese population...
  11. doi request reprint Vaccination with CD133(+) melanoma induces specific Th17 and Th1 cell-mediated antitumor reactivity against parental tumor
    Takao Miyabayashi
    Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Japan
    Cancer Immunol Immunother 60:1597-608. 2011
    ..Further, the treatment prevented regulatory T-cell induction. These results indicate that T-cell immunotherapy is a promising treatment option to eradicate CD133(+) drug-tolerant cells to obtain a cure for cancer...
  12. doi request reprint The efficacy of triplet antiemetic therapy with 0.75 mg of palonosetron for chemotherapy-induced nausea and vomiting in lung cancer patients receiving highly emetogenic chemotherapy
    Satoru Miura
    Department of Medicine II, Niigata University Medical and Dental Hospital, Niigata, Japan
    Support Care Cancer 21:2575-81. 2013
    ..The efficacy and safety of triplet therapy using a 0.75-mg dose of palonosetron have not yet been investigated. We performed a prospective phase II study using triplet antiemetic therapy with 0.75 mg of palonosetron...
  13. pmc Henoch Schönlein purpura associated with pulmonary adenocarcinoma
    Daiki Mifune
    Department of Medicine II, Niigata University Medical and Dental Hospital, 951 8520 Niigata, Japan
    J Med Case Reports 5:226. 2011
    ..abstract:..
  14. ncbi request reprint The duration of signaling through CD40 directs biological ability of dendritic cells to induce antitumor immunity
    Satoshi Watanabe
    Department of Homeostatic Regulation and Development, Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    J Immunol 171:5828-36. 2003
    ..The usage of DCs conditioned for the priming phase might provide significant advantages in anticancer immunotherapy...
  15. ncbi request reprint Short-term use of continuous positive airway pressure ameliorates glomerular hyperfiltration in patients with obstructive sleep apnoea syndrome
    Shin ichi Kinebuchi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, 951 8510, Japan
    Clin Sci (Lond) 107:317-22. 2004
    ..001). OSAS patients were generally in a glomerular-hyperfiltrating condition that appeared to cause the renal findings associated with OSAS. CPAP might prevent nephropathy by ameliorating the glomerular hyperfiltration in OSAS patients...
  16. ncbi request reprint Matrix metalloproteinase-1 activation via plasmin generated on alveolar epithelial cell surfaces
    Takashi Ishida
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, 951 8510, Niigata, Japan
    Lung 184:15-9. 2006
    ..Alveolar epithelial plasminogen activation is important in matrix metalloproteinase-1 activation and thus presumably in tissue remodeling in pulmonary fibrosing pulmonary diseases such as idiopathic pulmonary fibrosis...