Yasushi Tamura

Summary

Affiliation: Niigata University
Country: Japan

Publications

  1. doi request reprint Value of highly sensitive fucosylated fraction of alpha-fetoprotein for prediction of hepatocellular carcinoma recurrence after curative treatment
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi Dori 1 Bancho, Chuo Ku, Niigata, 951 8520, Japan
    Dig Dis Sci 58:2406-12. 2013
  2. doi request reprint Serum alpha-fetoprotein levels during and after interferon therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis C
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Dig Dis Sci 54:2530-7. 2009
  3. doi request reprint Clinical advantage of highly sensitive on-chip immunoassay for fucosylated fraction of alpha-fetoprotein in patients with hepatocellular carcinoma
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi Dori 1 Bancho, Chuo Ku, Niigata 951 8520, Japan
    Dig Dis Sci 55:3576-83. 2010
  4. doi request reprint Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM
    Atsunori Tsuchiya
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Science, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Japan
    Cancer Lett 309:95-103. 2011
  5. pmc Phase I study of miriplatin combined with transarterial chemotherapy using CDDP powder in patients with hepatocellular carcinoma
    Kenya Kamimura
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan
    BMC Gastroenterol 12:127. 2012
  6. pmc A safe and effective dose of cisplatin in hepatic arterial infusion chemotherapy for hepatocellular carcinoma
    Akihiko Osaki
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University Niigata, Niigata 951 8510, Japan
    Cancer Med 2:86-98. 2013
  7. pmc Active treatments are a rational approach for hepatocellular carcinoma in elderly patients
    Takeshi Suda
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Gastroenterol 19:3831-40. 2013
  8. pmc Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis
    Akihiko Osaki
    Department of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Gastroenterol 16:2918-25. 2010
  9. doi request reprint Formula to predict platelet count after partial splenic arterial embolization in patients with hypersplenism
    Akihiko Osaki
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    J Vasc Interv Radiol 23:900-7. 2012
  10. pmc Identification of cellular genes showing differential expression associated with hepatitis B virus infection
    Yasuo Fukuhara
    Yasuo Fukuhara, Takeshi Suda, Makoto Kobayashi, Yasushi Tamura, Masato Igarashi, Nobuo Waguri, Hirokazu Kawai, Yutaka Aoyagi, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Hepatol 4:139-48. 2012

Detail Information

Publications16

  1. doi request reprint Value of highly sensitive fucosylated fraction of alpha-fetoprotein for prediction of hepatocellular carcinoma recurrence after curative treatment
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi Dori 1 Bancho, Chuo Ku, Niigata, 951 8520, Japan
    Dig Dis Sci 58:2406-12. 2013
    ..Recently, a highly sensitive immunoassay using an on-chip electrokinetic reaction and separation by affinity electrophoresis (micro-total analysis system; μTAS) has been developed...
  2. doi request reprint Serum alpha-fetoprotein levels during and after interferon therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis C
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Dig Dis Sci 54:2530-7. 2009
    ..057), and a significantly higher cumulative incidence of HCC was seen in patients with increased serum AFP levels at EOT (P = 0.021). Serum AFP level at EOT is a possible predictor of HCC in CHC patients after IFN therapy...
  3. doi request reprint Clinical advantage of highly sensitive on-chip immunoassay for fucosylated fraction of alpha-fetoprotein in patients with hepatocellular carcinoma
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi Dori 1 Bancho, Chuo Ku, Niigata 951 8520, Japan
    Dig Dis Sci 55:3576-83. 2010
    ..However, AFP-L3 has not always been reliable in cases with low serum AFP concentrations. Recently, a novel automated immunoassay for AFP-L3, the micro-total analysis system (μ-TAS), has been developed...
  4. doi request reprint Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM
    Atsunori Tsuchiya
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Science, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Japan
    Cancer Lett 309:95-103. 2011
    ..The 140-kDa NCAM isoform was specifically detected in the "highly soluble" NCAM group of HCC patients andits related signals are potential drug targets for NCAM+ HCC...
  5. pmc Phase I study of miriplatin combined with transarterial chemotherapy using CDDP powder in patients with hepatocellular carcinoma
    Kenya Kamimura
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan
    BMC Gastroenterol 12:127. 2012
    ....
  6. pmc A safe and effective dose of cisplatin in hepatic arterial infusion chemotherapy for hepatocellular carcinoma
    Akihiko Osaki
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University Niigata, Niigata 951 8510, Japan
    Cancer Med 2:86-98. 2013
    ..73 m(2)) upon an assumption of HCC doubling time of 90 days, and the targeted liver is smaller than 200 times the CDDP dose (mg). A further analysis is required to define appropriate injection speeds...
  7. pmc Active treatments are a rational approach for hepatocellular carcinoma in elderly patients
    Takeshi Suda
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Gastroenterol 19:3831-40. 2013
    ..To determine whether an active intervention is beneficial for the survival of elderly patients with hepatocellular carcinoma (HCC)...
  8. pmc Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis
    Akihiko Osaki
    Department of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Gastroenterol 16:2918-25. 2010
    ..To investigate whether a noninvasive measurement of tissue strain has a potential usefulness for management of nonalcoholic steatohepatitis (NASH)...
  9. doi request reprint Formula to predict platelet count after partial splenic arterial embolization in patients with hypersplenism
    Akihiko Osaki
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    J Vasc Interv Radiol 23:900-7. 2012
    ..To establish a formula to guide appropriate embolization volume for postprocedural platelet gain following partial splenic arterial embolization (PSE) for hypersplenism...
  10. pmc Identification of cellular genes showing differential expression associated with hepatitis B virus infection
    Yasuo Fukuhara
    Yasuo Fukuhara, Takeshi Suda, Makoto Kobayashi, Yasushi Tamura, Masato Igarashi, Nobuo Waguri, Hirokazu Kawai, Yutaka Aoyagi, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8122, Japan
    World J Hepatol 4:139-48. 2012
    ..To investigate the impact of hepatitis B virus (HBV) infection on cellular gene expression, by conducting both in vitro and in vivo studies...
  11. doi request reprint Fucosylated fraction of alpha-fetoprotein as a predictor of prognosis in patients with hepatocellular carcinoma after curative treatment
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Chuo Ku, Niigata, Japan
    Dig Dis Sci 55:2095-101. 2010
    ..The aim of this study was to evaluate the clinical usefulness of measuring the Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) for prognostic predictor in patients with hepatocellular carcinoma (HCC)...
  12. ncbi request reprint Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor
    Masaaki Takamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi dori 1, Chuo Ku, Niigata 951 8510, Japan
    Int J Oncol 36:245-54. 2010
    ..Loss of LI-cadherin results in up-regulation of MTF-1 and PlGF, thereby regulating angiogenesis in ICC...
  13. ncbi request reprint Progress toward liver-based gene therapy
    Takeshi Suda
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Niigata, Japan
    Hepatol Res 39:325-40. 2009
    ..This review describes the fundamentals of gene delivery, and the preclinical and clinical progress that has been made toward gene therapy using the liver as a target...
  14. ncbi request reprint Fucosylated fraction of alpha-fetoprotein, L3, as a useful prognostic factor in patients with hepatocellular carcinoma with special reference to low concentrations of serum alpha-fetoprotein
    Makoto Kobayashi
    Division of Gastroenterology and Hepatology, Department of Cellular Function, Course for Molecular and Cellular Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    Hepatol Res 37:914-22. 2007
    ..Conclusions: The present study indicates that the L3 fraction before treatment serves as a useful prognostic indicator when the serum concentrations of AFP were very low...
  15. doi request reprint History and recent progress in evaluation of the fucosylated alpha-fetoprotein fraction
    Yutaka Aoyagi
    Division of Gastroenterology and Hepatology, Department of Cellular Function, Course for Molecular and Cellular Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
    J Gastroenterol Hepatol 26:615-6. 2011
    ..See article in J. Gastroenterol. Hepatol. 2011; 26: 739-744...
  16. ncbi request reprint An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins
    Masaaki Takamura
    Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata 951 8510, Japan
    Life Sci 80:1335-44. 2007
    ..These results confirm the role of JNK as a critical apoptotic mediator in GalN/LPS-induced FHF. SP600125 has the potential to protect FHF by downregulating Bad and inhibiting Bid cleavage...