Research Topics
| Reiko SaitoSummaryAffiliation: Niigata University Country: Japan Publications
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Detail Information
Publications
Detection of amantadine-resistant influenza A virus strains in nursing homes by PCR-restriction fragment length polymorphism analysis with nasopharyngeal swabsReiko Saito
Department of Public Health, Niigata University, School of Medicine, Niigata City, Niigata, 951 8510, Japan
J Clin Microbiol 40:84-8. 2002....
An off-seasonal amantadine-resistant H3N2 influenza outbreak in JapanReiko Saito
Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Japan
Tohoku J Exp Med 210:21-7. 2006..Our findings suggested that an off-season community influenza outbreak in Nagasaki was caused by a distinct clade in H3N2 (named clade N), which possessed characteristics of amantadine resistance...
Geographic mapping method shows potential for mapping influenza activity in EuropeReiko Saito
Department of Public Health, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan
Euro Surveill 10:E051027.6. 2005
Reduced effectiveness of oseltamivir in children infected with oseltamivir-resistant influenza A (H1N1) viruses with His275Tyr mutationReiko Saito
Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences, Niigata City, Niigata Prefecture, Japan
Pediatr Infect Dis J 29:898-904. 2010..Little is known about whether neuraminidase inhibitors are effective for children infected with oseltamivir-resistant influenza A(H1N1) viruses...
Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2Reiko Saito
Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 41:2164-5. 2003..Predominant amino acid substitutions in M2 protein occurred at position 31 (serine to asparagine) in H3N2 strains and at position 27 (valine to alanine) in H1N1 strains...
High prevalence of amantadine-resistance influenza a (H3N2) in six prefectures, Japan, in the 2005-2006 seasonReiko Saito
Department of Public Health, Niigata University, Graduate School of Medical and Dental Science, Niigata, Japan
J Med Virol 79:1569-76. 2007..Antiviral resistance monitoring should be intensified and maintained for rapid feedback into treatment strategies, and selection of alternative therapeutic agents...
Molecular evolution of human influenza A viruses in a local area during eight influenza epidemics from 2000 to 2007Hassan Zaraket
Division of Public Health, Department of Infectious Disease Control and International Medicine, Graduate School of Medical and Dental Sciences, Niigata University, 1 757, Asahimachi Dori, Niigata, Niigata 951 8510, Japan
Arch Virol 154:285-95. 2009..Finally, acquisition or loss of N-glycosylation sites was shown to contribute to the evolution of influenza A virus, especially in the case of H3N2, which had a higher tendency to acquire new glycosylation sites...
Emerging genotypes of human respiratory syncytial virus subgroup A among patients in JapanYugo Shobugawa
Department of Infectious Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Niigata City, Japan
J Clin Microbiol 47:2475-82. 2009..Continuing studies to follow up the genetic changes and to clarify the mechanism of reinfection in HRSV are important steps to understand HRSV infections...
Epidemiology of human influenza A and B viruses in Myanmar from 2005 to 2007Clyde Dapat
Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951 8510, Japan
Intervirology 52:310-20. 2009..To perform genetic analysis of influenza A and B viruses in Myanmar from 2005 to 2007 and to determine the prevalence of amantadine-resistant influenza A viruses...
Genetic makeup of amantadine-resistant and oseltamivir-resistant human influenza A/H1N1 virusesHassan Zaraket
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan
J Clin Microbiol 48:1085-92. 2010....
Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 seasonTatiana Baranovich
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Chuoku, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Virol 47:23-8. 2010..A substantial increase in oseltamivir-resistant A(H1N1) influenza viruses was reported in Europe in late 2007...
New genotypes within respiratory syncytial virus group B genotype BA in Niigata, JapanIsolde C Dapat
Division of Public Health, Department of Infectious Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 48:3423-7. 2010..These new genotypes were not associated with large outbreaks in the community...
Genomic events contributing to the high prevalence of amantadine-resistant influenza A/H3N2Hassan Zaraket
Division of Public Health, Department of Infectious Disease Control and International Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Antivir Ther 15:307-19. 2010..The aim of this study was to clarify the genomic events contributing to the evolution and continuity of the N-lineage amantadine-resistant viruses...
Effectiveness of oseltamivir treatment among children with influenza A or B virus infections during four successive winters in Niigata City, JapanMaki Sato
Department of Public Health, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Tohoku J Exp Med 214:113-20. 2008..Our data provide evidence that oseltamivir is beneficial for influenza infections, but the effectiveness is differed by type and age...
Recurrence and persistence of fever in children who developed amantadine-resistant influenza viruses after treatmentYugo Shobugawa
Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Tohoku J Exp Med 214:129-38. 2008..s.). Therefore, we concluded that younger children were prone to develop amantadine-resistance after treatment and showed a significant recurrence of fever on day 4 and/or 5, and the course of illness was consequently prolonged...
Emergence of amantadine-resistant influenza A viruses: epidemiological studyHiroshi Suzuki
Department of Public Health, Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata 951 8510, Japan
J Infect Chemother 9:195-200. 2003..Measures should be taken to reduce contact, as much as possible, between persons taking and those not taking antiviral drugs for treatment or chemoprophylaxis...
Rapid and specific detection of amantadine-resistant influenza A viruses with a Ser31Asn mutation by the cycling probe methodYasushi Suzuki
Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences, 1 757, Asahimachi Dori, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 48:57-63. 2010....
Identification of oseltamivir resistance among pandemic and seasonal influenza A (H1N1) viruses by an His275Tyr genotyping assay using the cycling probe methodYasushi Suzuki
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University, Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Chuo Ward, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 49:125-30. 2011..This method is applicable to routine laboratory-based monitoring of drug resistance and patient management during antiviral therapy...
Antiviral drug susceptibilities of seasonal human influenza viruses in Lebanon, 2008-09 seasonHassan Zaraket
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan
J Med Virol 82:1224-8. 2010..Continued surveillance is important to fully elucidate influenza patterns in Lebanon and the Middle East in general, especially in light of the current influenza pandemic...
High frequency of repeated infections due to emerging genotypes of human respiratory syncytial viruses among children during eight successive epidemic seasons in JapanMasahiro Yamaguchi
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata Prefecture 951 8510, Niigata City, Japan
J Clin Microbiol 49:1034-40. 2011....
Phylogenetic analysis of an off-seasonal influenza virus A (H3N2) in Niigata, Japan, 2010Clyde Dapat
Department of Public Health, Graduate School of Medicine and Dental Sciences, Niigata University, Niigata 951 8510, Japan
Jpn J Infect Dis 64:237-41. 2011..Whole genome analysis revealed that the virus was similar to the A/Perth/16/2009 strain and that it is a triple reassortant virus with a 3+3+2 pattern of segment recombination...
Epidemiologic study of influenza infection in Okinawa, Japan, from 2001 to 2007: changing patterns of seasonality and prevalence of amantadine-resistant influenza A virusYasushi Suzuki
Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences, 1 757, Asahimachi Dori, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 47:623-9. 2009....
Antibody response to influenza vaccination in nursing home residents and healthcare workers during four successive seasons in Niigata, JapanMizuho Sato
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University, Niigata Prefecture 951 8510, Japan
Infect Control Hosp Epidemiol 26:859-66. 2005..To evaluate the antibody response to influenza vaccines in nursing home residents and healthcare workers (HCWs) and its relation to residents' functional and chronic disease status during four successive seasons...
Rare influenza A (H3N2) variants with reduced sensitivity to antiviral drugsClyde Dapat
Department of Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Emerg Infect Dis 16:493-6. 2010..These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2...
Molecular epidemiology of respiratory syncytial virus infections among children with acute respiratory symptoms in a community over three seasonsMizuho Sato
Division of Public Health, Department of Infectious Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Niigata City, Niigata Prefecture, 951-8510, Japan
J Clin Microbiol 43:36-40. 2005..Support for determination of the genotype by RT-PCR as an effective tool for characterization of RSV circulation patterns in the community is provided...
Genetic analysis of influenza A/H3N2 and A/H1N1 viruses circulating in Vietnam from 2001 to 2006Danjuan Li
Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences, 1 757, Asahimachi Dori, Niigata City, Niigata Prefecture 951 8510, Japan
J Clin Microbiol 46:399-405. 2008..As influenza viruses circulate throughout the year, we emphasize the importance of surveillance in tropical and subtropical zones, where the emergence of new strains may be detected earlier than it is in temperate zones...
Genetic characterization of human influenza viruses in the pandemic (2009-2010) and post-pandemic (2010-2011) periods in JapanIsolde C Dapat
Division of International Health, Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
PLoS ONE 7:e36455. 2012..This study aims to characterize human influenza viruses circulating in Japan in the pandemic and post-pandemic periods and to determine the prevalence of antiviral-resistant viruses...
In vivo and in vitro alterations in influenza A/H3N2 virus M2 and hemagglutinin genes: effect of passage in MDCK-SIAT1 cells and conventional MDCK cellsDanjuan Li
Department of Public Health, Graduate School of Medical and Dental Science, Niigata University, Niigata, Japan
J Clin Microbiol 47:466-8. 2009..However, genetic changes occurred after serial passage in either MDCK or MDCK-SIAT1 cells. Our results showed that only a few mutations were observed in MDCK-SIAT1-passaged isolates in the presence of amantadine...
Molecular characteristics of outbreaks of nosocomial infection with influenza A/H3N2 virus variantsTaeko Oguma
Division of Public Health, Department of Infectious Disease Control and International Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Infect Control Hosp Epidemiol 32:267-75. 2011..To describe outbreaks of nosocomial influenza infection with molecular methods and to elucidate the viral linkages among outbreak case patients including both inpatients and healthcare workers (HCWs)...
Clinical effectiveness of neuraminidase inhibitors--oseltamivir, zanamivir, laninamivir, and peramivir--for treatment of influenza A(H3N2) and A(H1N1)pdm09 infection: an observational study in the 2010-2011 influenza season in JapanYugo Shobugawa
Department of International Health, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata 951 8510, Japan
J Infect Chemother 18:858-64. 2012..Further evaluation of the clinical effectiveness of the newly released NAIs for influenza-infected patients, including those infected with A(H1N1)pdm09, is needed...
Geographic and temporal trends in influenzalike illness, Japan, 1992-1999Takatsugu Sakai
Department of Public Health, Niigata University School of Medicine, Niigata 951 8510, Japan
Emerg Infect Dis 10:1822-6. 2004..Applying the kriging method allowed better visualization and understanding of spatiotemporal trends in seasonal ILI activity. This method will likely be an important tool for future influenza surveillance in Japan...
Prevalence of human metapneumovirus and influenza virus infections among Japanese children during two successive wintersAsami Sasaki
Department of Public Health, Niigata University, School of Medicine, Japan
Pediatr Infect Dis J 24:905-8. 2005..The objective of this study was to identify links between hMPV and influenza virus infections among children with influenza-like illness...
Geodemographics profiling of influenza A and B virus infections in community neighborhoods in JapanYoshinari Kimura
Division of Public Health, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
BMC Infect Dis 11:36. 2011..We aimed to clarify the relationship between the incidence of influenza and neighborhood characteristics using GIS and identified the type of small areas where influenza occurs frequently or infrequently...
The effectiveness of influenza vaccine against influenza a (H3N2) virus infections in nursing homes in Niigata, Japan, during the 1998-1999 and 1999-2000 seasonsReiko Saito
Department of Public Health, Niigata University School of Medicine, Niigata City, Japan
Infect Control Hosp Epidemiol 23:82-6. 2002..CONCLUSIONS: A high vaccination rate for both residents and HCWs may reduce the risk of ILI and institutional outbreaks in nursing homes...
Association of early annual peak influenza activity with El Niño southern oscillation in JapanHassan Zaraket
Department of Infectious Disease Control and International Medicine, Division of Public Health, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Influenza Other Respi Viruses 2:127-30. 2008..El Niño southern oscillation (ENSO), which involves two extreme events, El Niño and La Niña, is well-known for its large effects on inter-annual climate variability. The influence of ENSO on several diseases has been described...
Measles outbreaks in high schools closely associated with sporting events in Niigata, JapanAsami Sasaki
Department of Public Health, Niigata University Graduate School of Medical and Dental Sciences, 1 757, Asahimachi Dori, Niigata City, Niigata 951 8510, Japan
J Infect 55:179-83. 2007..Due to high vaccine coverage in Niigata, we had no outbreaks of measles from 1997 to 2003 but an opportunity to study the role of sporting events in the propagation of an epidemic was experienced in the spring of the latter year...
[Antiviral resistance of influenza viruses]Reiko Saito
Department of Public Health, Niigata University, Graduate School of Medical and Dental Sciences
Nippon Rinsho 65:471-5. 2007
Prolonged effects of participation in disaster relief operations after the Mid-Niigata earthquake on increased cardiovascular risk among local governmental staffTomoko Azuma
Division of Public Health, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Hypertens 28:695-702. 2010..The aim of this study was to clarify how disaster-related administrative workloads affect the cardiovascular risk factors of local governmental staff...
