N Otsuka

Summary

Affiliation: Niigata University
Country: Japan

Publications

  1. ncbi request reprint CAG repeat disorder models and human neuropathology: similarities and differences
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, 1 Asahimachi, Niigata, 951 8585, Japan
    Acta Neuropathol 115:71-86. 2008
  2. ncbi request reprint Ultrastructural localization of CD38 immunoreactivity in rat brain
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Asahimachi 1, Japan
    Brain Res 756:52-60. 1997
  3. ncbi request reprint Polyglutamine disease: recent advances in the neuropathology of dentatorubral-pallidoluysian atrophy
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Neuropathology 26:346-51. 2006
  4. ncbi request reprint Sharing of polyglutamine localization by the neuronal nucleus and cytoplasm in CAG-repeat diseases
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Neuropathol Appl Neurobiol 30:665-75. 2004
  5. ncbi request reprint Genotype-phenotype correlation in CAG-repeat diseases
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Neuropathology 22:317-22. 2002
  6. ncbi request reprint Oligodendrocytic polyglutamine pathology in dentatorubral-pallidoluysian atrophy
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, 1 Asahimachi, Niigata 951 8585, Japan
    Ann Neurol 52:670-4. 2002
  7. ncbi request reprint Involvement of lysosomes in the pathogenesis of CAG repeat diseases
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Ann Neurol 52:498-503. 2002
  8. pmc Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseases
    M Yamada
    Departments of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Am J Pathol 159:1785-95. 2001
  9. ncbi request reprint Involvement of the cerebral cortex and autonomic ganglia in Machado-Joseph disease
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Acta Neuropathol 101:140-4. 2001
  10. ncbi request reprint Pathology of CAG repeat diseases
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Neuropathology 20:319-25. 2000

Detail Information

Publications14

  1. ncbi request reprint CAG repeat disorder models and human neuropathology: similarities and differences
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, 1 Asahimachi, Niigata, 951 8585, Japan
    Acta Neuropathol 115:71-86. 2008
    ....
  2. ncbi request reprint Ultrastructural localization of CD38 immunoreactivity in rat brain
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Asahimachi 1, Japan
    Brain Res 756:52-60. 1997
    ..Oligodendrocytes and microglia were immunonegative for CD38. The pattern of distribution of CD38 in the CNS is suggestive of multiple roles for this molecule at various functional sites in both neurons and astrocytes...
  3. ncbi request reprint Polyglutamine disease: recent advances in the neuropathology of dentatorubral-pallidoluysian atrophy
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Neuropathology 26:346-51. 2006
    ..Polyglutamine diseases have a similarity with neuronal storage disease, and this pathological process might become a target for the establishment of an effective therapy for these diseases...
  4. ncbi request reprint Sharing of polyglutamine localization by the neuronal nucleus and cytoplasm in CAG-repeat diseases
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Neuropathol Appl Neurobiol 30:665-75. 2004
    ....
  5. ncbi request reprint Genotype-phenotype correlation in CAG-repeat diseases
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Neuropathology 22:317-22. 2002
    ..This novel pathology may become a clue for elucidating molecular mechanisms of neuronal dysfunction and establishing clinicopathological correlations in CAG-repeat diseases...
  6. ncbi request reprint Oligodendrocytic polyglutamine pathology in dentatorubral-pallidoluysian atrophy
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, 1 Asahimachi, Niigata 951 8585, Japan
    Ann Neurol 52:670-4. 2002
    ..These findings suggest that glial cells in dentatorubral-pallidoluysian atrophy also are involved in the polyglutamine pathogenesis...
  7. ncbi request reprint Involvement of lysosomes in the pathogenesis of CAG repeat diseases
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Ann Neurol 52:498-503. 2002
    ....
  8. pmc Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseases
    M Yamada
    Departments of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Am J Pathol 159:1785-95. 2001
    ..The results suggest that the interaction between NIIs and nuclear bodies may play a role in the pathogenesis of CAG repeat diseases...
  9. ncbi request reprint Involvement of the cerebral cortex and autonomic ganglia in Machado-Joseph disease
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Acta Neuropathol 101:140-4. 2001
    ..These lesions, newly recognized by polyglutamine immunohistochemistry, may be responsible for the cerebral cortical dysfunctions or autonomic abnormalities pointed out in MJD patients by the recent clinical and neuroradiological studies...
  10. ncbi request reprint Pathology of CAG repeat diseases
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Neuropathology 20:319-25. 2000
    ....
  11. ncbi request reprint Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Japan
    Ann Neurol 49:14-23. 2001
    ....
  12. ncbi request reprint Ubiquitinated filamentous inclusions in cerebellar dentate nucleus neurons in dentatorubral-pallidoluysian atrophy contain expanded polyglutamine stretches
    M Yamada
    Department of Pathology, Niigata University, Japan
    Acta Neuropathol 99:615-8. 2000
    ....
  13. ncbi request reprint Localization of Bcl-xbeta in the developing and adult rat central nervous system
    M Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Asahimachi 1, Niigata, Japan
    J Neurosci Res 60:468-77. 2000
    ..These results suggest that Bcl-xbeta plays an important role throughout the CNS in developing stage and may regulate the apoptosis of postnatal CNS neurons...
  14. ncbi request reprint Separate CNS lesions involving the brainstem and spinal cord in a 47-year-old man
    Mitsunori Yamada
    Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan
    Neuropathology 28:341-4. 2008