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Genomes and Genes | I NaritaSummaryAffiliation: Niigata University Country: Japan Publications
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Publications
Uremic pruritus in chronic hemodialysis patientsIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Nephrol 21:161-5. 2008..Early diagnosis and treatment of uremic pruritus focusing on general strategies that include the optimization of dialysis dose, erythropoiesis-stimulating agents, and management of secondary hyperparathyroidism is recommended...
Henoch Schönlein purpura associated with pulmonary adenocarcinomaDaiki Mifune
Department of Medicine II, Niigata University Medical and Dental Hospital, 951 8520 Niigata, Japan
J Med Case Reports 5:226. 2011..abstract:..- Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysisSatoshi Watanabe
Department of Medicine, Niigata University Medical and Dental Hospital, Niigata City, Japan
BMC Cancer 11:1. 2011..The present study was conducted to evaluate the efficacy and toxicity of the 2(nd) EGFR-TKI administration... - Identification of genes specifically expressed in chronic and progressive glomerulosclerosisI Narita
Department of Medicine II, Niigata University Medical School, Japan
Kidney Int Suppl 63:S215-7. 1997..These genes may play important roles in the process which promotes acute glomerular damage advance to chronic and progressive glomerulosclerosis... - Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patientsIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 757, Asahimachi Dori, Niigata, 951 8510, Japan
Hypertension 42:304-9. 2003..65, P=0.2902). These findings suggest an interaction between ACE and ADD1 polymorphisms not only on blood pressure regulation but also on the progression of renal dysfunction in patients with IgAN... - Role of genetic polymorphism in the SA gene on the blood pressure and prognosis of renal function in patients with immunoglobulin A nephropathyIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Hypertens Res 25:831-6. 2002..Further, they suggest that the sensitivity to this gene polymorphism increases in patients with renal injury... - The genetic susceptibility to IgA nephropathy: a novel functional candidate gene for incomplete O-glycosylation of IgA1I Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 71:379-81. 2007..Although underglycosylation was reported to be an acquired abnormality, genes for enzymes of O-glycosylation, such as C1GALT1, may be responsible for susceptibility to IgA nephropathy... - Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patientsI Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 69:1626-32. 2006..Severe uremic pruritus caused by multiple factors, not only affects the quality of life but may also be associated with poor outcome in chronic hemodialysis patients... - Angiotensinogen gene variation and renoprotective efficacy of renin-angiotensin system blockade in IgA nephropathyIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 64:1050-8. 2003..The interindividual variation in response to the RAS blockade may be in part genetically determined, whereas the results have been controversial... - Genetic polymorphism of NPHS1 modifies the clinical manifestations of Ig A nephropathyIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Niigata, Japan
Lab Invest 83:1193-200. 2003..This study suggests that the NPHS1 G349A polymorphism may be associated with heavy proteinuria and a decline in renal function in patients with IgAN... 
Pathogenetic significance of aberrant glycosylation of IgA1 in IgA nephropathyIchiei Narita
Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 757, Asahimachi Dori, Niigata, 951 8510, Japan
Clin Exp Nephrol 12:332-8. 2008..This review will focus on and discuss the role of incompleteness of IgA1 O-galactosylation in the pathogenesis of IgAN and propose a possible mechanism in which abnormal IgA1 occurs in IgAN...- Role of uteroglobin G38A polymorphism in the progression of IgA nephropathy in Japanese patientsIchiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences 1 757, Asahimachi Dori, Niigata, 951 8510, Japan
Kidney Int 61:1853-8. 2002..A genetic polymorphism in uteroglobin has been reported to be associated with progression of IgA nephropathy in a Caucasian population, but the findings remain controversial... - Genetic polymorphisms in the promoter and 5' UTR region of the Fc alpha receptor (CD89) are not associated with a risk of IgA nephropathyI Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
J Hum Genet 46:694-8. 2001..The present study indicates that the analyzed polymorphisms of the FcalphaR gene do not appear to be primarily involved in the susceptibility to IgAN... - Transforming growth factor-beta1 gene polymorphism modifies the histological and clinical manifestations in Japanese patients with IgA nephropathyF Sato
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Tissue Antigens 64:35-42. 2004..These results suggest that TGF-beta1 gene polymorphisms are specifically associated with heavy proteinuria and mesangial cell proliferation in Japanese patients with IgAN, although they do not confer susceptibility to this disease... - Association of gene polymorphism of polymeric immunoglobulin receptor and IgA nephropathyI Narita
Department of Medicine II, Niigata University Medical School
Intern Med 40:867-72. 2001.... - Peroxisome proliferator-activated receptor gamma C161T polymorphisms and survival of Japanese patients with immunoglobulin A nephropathyJ Song
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Niigata, Japan
Clin Genet 64:398-403. 2003..We report that the PPARG C161T polymorphism is associated with the survival of IgAN patients without hypertension. The T allele of the polymorphism might have a protective effect on the progression of IgAN... - The combined genotypes of stimulatory and inhibitory Fc gamma receptors associated with systemic lupus erythematosus and periodontitis in Japanese adultsTetsuo Kobayashi
Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Periodontol 78:467-74. 2007..Therefore, we evaluated whether the combination of FcgammaR or IL-1 polymorphic genes represents a common risk factor for SLE and periodontitis... - Maxacalcitol therapy decreases circulating osteoprotegerin levels in dialysis patients with secondary hyperparathyroidismJ J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Nephrol 64:64-8. 2005..Little is known about the effects of vitamin D therapy on the circulating osteoprotegerin levels in dialysis patients... - Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyteY Tsubata
Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 70:1948-54. 2006.... - Down-regulation of interferon-gamma signaling by gene transfer of Stat1 mutant in mesangial cellsM Sakatsume
Department of Medicine II and Research Laboratory for Molecular Genetics, Niigata University School of Medicine, Niigata, Japan
Kidney Int 57:455-63. 2000..We investigated Stat1alpha activation by IFN-gamma in mesangial cells and attempted to regulate the signal transduction by gene transfer... - Risk of periodontitis in systemic lupus erythematosus is associated with Fcgamma receptor polymorphismsTetsuo Kobayashi
Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Periodontol 74:378-84. 2003..The aim of this study was therefore to evaluate whether FcgammaR gene polymorphisms are associated with periodontitis risk in SLE patients... - Human glomerulonephritis accompanied by active cellular infiltrates shows effector T cells in urineM Sakatsume
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Am Soc Nephrol 12:2636-44. 2001..These findings suggest that the appearance of effector T cells in urine may reflect the cellular immune reaction that occurs in the kidneys of patients with GN accompanied by active cell infiltration... - Patients undergoing dialysis therapy for 30 years or more survive with serious osteoarticular disordersS Yamamoto
Division of Clinical Nephrology and Rheumatology, Niigata University Medical and Dental Hospital, Niigata, Japan
Clin Nephrol 70:496-502. 2008..The aim of the study was to investigate the characteristics, such as dialysis-related complications, in chronic kidney disease (CKD) Stage 5D patients undergoing dialysis therapy for more than 30 years or more... - The circadian blood pressure rhythm in non-diabetic hemodialysis patientsI Narita
Department of Medicine II, Niigata University School of Medicine, Japan
Hypertens Res 24:111-7. 2001..The increased dRen observed only in ID patients may reflect occult cardiovascular damage or functional disturbances in aortic and carotid baroreflexes caused by arterial structural changes... - Pretreatment plasma intact parathyroid hormone and serum calcium levels, but not serum phosphate levels, predict the response to maxacalcitol therapy in dialysis patients with secondary hyperparathyroidismYuko Oyama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-751 Asahimachi-dori, Niigata 951-8510, Japan
Clin Exp Nephrol 9:142-7. 2005..0001). CONCLUSIONS: Serum Ca levels and parathyroid function were correlated with the results of maxacalcitol therapy. Pretreatment serum Pi levels could not predict the result... - SAA1 gene polymorphisms and the risk of AA amyloidosis in Japanese patients with rheumatoid arthritisJunya Ajiro
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata, 951 8510, Japan
Mod Rheumatol 16:294-9. 2006..Both C-13T and C2995T were associated with the development of amyloidosis. Examining both polymorphisms may be more useful than examining only one of them for estimating the risk of the development of amyloidosis... - [Gene polymorphisms of renin-angiotensin system in patients with kidney diseases]Ichiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Nippon Rinsho 62:1811-5. 2004.... - Alterations in serum phosphate levels predict the long-term response to intravenous calcitriol therapy in dialysis patients with secondary hyperparathyroidismKiyoko Hosaka
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 751 Asahimachi dori, Niigata, Niigata 951 8510, Japan
J Bone Miner Metab 26:185-90. 2008..Changes in treatment are recommended if patients show unsatisfactory parathyroid suppression with a hyperphosphatemic tendency... - Effective anti-TNF-alpha therapy can induce rapid resolution and sustained decrease of gastroduodenal mucosal amyloid deposits in reactive amyloidosis associated with rheumatoid arthritisTakeshi Kuroda
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Cyuo ku, Niigata, Japan
J Rheumatol 36:2409-15. 2009..To examine the effect of anti-tumor necrosis factor-alpha (anti-TNF) therapy in patients with reactive AA amyloidosis associated with rheumatoid arthritis (RA)... - Monocyte chemoattractant protein-1 A-2518G gene polymorphism and renal survival of Japanese patients with immunoglobulin A nephropathyHonami Mori
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Exp Nephrol 9:297-303. 2005..However, the correlation of MCP-1 gene polymorphism with the long-term prognosis of Japanese patients with IgAN has not been clearly determined yet... - SM22alpha: the novel phenotype marker of injured glomerular epithelial cells in anti-glomerular basement membrane nephritisAsa Ogawa
Division of Clinical Nephrology and Rheumatology, Institute of Nephrology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Nephron Exp Nephrol 106:e77-87. 2007..SM22alpha is a 22-kDa cytoskeletal protein that is exclusively expressed in smooth muscle cells. We investigated the localization of SM22alpha at mRNA and protein levels, and its pathological significance in anti-GBM nephritis kidneys... - Recent progress in understanding dialysis-related amyloidosisSuguru Yamamoto
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science, Niigata, 951 8510, Japan
Bone 45:S39-42. 2009..DRA is one of the most harmful osteoarticular complications with regard to the maintenance of daily activities and quality of life in patients undergoing long-term dialysis therapy, in addition to the classical complications of CKD-MBD... - Development of hungry bone syndrome after rapid lowering of PTH with intravenous maxacalcitol therapy in a patient with non-uremic secondary hyperparathyroidismJ J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata University Medical Hospital, Niigata, Japan
Clin Nephrol 60:369-71. 2003..In conclusion, maxacalcitol therapy satisfactorily suppressed parathyroid function in a patient with secondary hyperparathyroidism without uremia. Appropriate Ca supplementation was required to perform it safely... - Maxacalcitol is a possible less phosphatemic vitamin D analogJunichiro J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Ther Apher Dial 9:352-4. 2005..05). Thus, maxacalcitol is a possible less phosphatemic active vitamin D agent, if not non-phosphatemic agent, which might reduce the risk of extraskeletal calcification... - A(-20)C polymorphism of the angiotensinogen gene and progression of IgA nephropathyShin Goto
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi 1 757, Niigata 951 8510, Japan
Kidney Int 62:980-5. 2002..Recent studies showed that nucleotide substitution in the 5' upstream core promoter region of AGT affects the basal transcription rate of the gene... - Abeta-2M-amyloidosis and related bone diseasesJunichiro James Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 754 Asahimachi dori, Niigata, 951 8510, Japan
J Bone Miner Metab 24:182-4. 2006..The precise cell biological mechanism of this inflammatory change is unknown. Further studies are needed to establish specific treatments against this as yet unsolved problem with long-term dialysis therapy... - Circulating 1-84 PTH and large C-terminal PTH fragment levels in uremiaJunichiro James Kazama
Division of Clinical Nephrology and Intensive Care Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Exp Nephrol 7:144-9. 2003..The so-called "intact parathyroid hormone (iPTH)" assay detects large C-terminal PTH fragments that are lacking several N-terminal amino acid residues in addition to 1-84 PTH molecules... - Circulating osteoprotegerin affects bone metabolism in dialysis patients with mild secondary hyperparathyroidismJunichiro James Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Ther Apher Dial 10:262-6. 2006..Circulating OPG might have a suppressive effect on osteoclastic bone resorption in dialysis patients... - The interleukin-1 and Fcgamma receptor gene polymorphisms in Japanese patients with rheumatoid arthritis and periodontitisTetsuo Kobayashi
Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
J Periodontol 78:2311-8. 2007..Therefore, we evaluated whether the IL-1 and FcgammaR gene polymorphisms represent a common risk factor for RA and periodontitis... - Histological differences in new-onset IgA nephropathy between children and adultsYohei Ikezumi
Department of Pediatrics, Niigata University Medical and Dental Hospital, Asahimachi Dori, Niigata 951 8510, Japan
Nephrol Dial Transplant 21:3466-74. 2006..We addressed this question by comparing both histology and leucocyte accumulation in biopsies of recently diagnosed childhood and adult IgAN... - The efficacy of tonsillectomy on long-term renal survival in patients with IgA nephropathyYuansheng Xie
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 63:1861-7. 2003..22; 95% CI, 0.06 to 0.76; P = 0.0164) had a significant effect on renal outcome. CONCLUSION: These results indicate that tonsillectomy has a favorable effect on long-term renal survival in patients with IgAN... - Macrophage metalloelastase as a major factor for glomerular injury in anti-glomerular basement membrane nephritisYoshikatsu Kaneko
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences and Kidney Center, Shinraku en Hospital, Niigata, Japan
J Immunol 170:3377-85. 2003..These results disclosed that MMP-12 played an important role in glomerular injury in a crescentic glomerulonephritis model, and inhibition of MMP-12 may lead to a new therapeutic strategy for this disease... - LCAT-dependent conversion of prebeta1-HDL into alpha-migrating HDL is severely delayed in hemodialysis patientsTakashi Miida
Division of Clinical Preventive Medicine, Department of Community Preventive Medicine, Niigata University, Graduate School of Medical and Dental Sciences, Japan
J Am Soc Nephrol 14:732-8. 2003..001). In conclusion, the LCAT-dependent conversion of prebeta1-HDL to alpha-migrating HDL is severely delayed in hemodialysis patients. The impaired catabolism of prebeta1-HDL may accelerate atherosclerosis in hemodialysis patients... - Rapid and sensitive electrophoresis of urinary protein clearly reveals the pathophysiological feature of renal diseasesMinoru Sakatsume
Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Nephrology (Carlton) 12:191-6. 2007..However, this method has not been used routinely because of its difficulty in obtaining a clear image. This study was performed in order to re-evaluate this method with an improved system... - Comparison of quantitative cancellous bone connectivity analyses at two- and three-dimensional levels in dialysis patientsJunichiro James Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 754 Asahimachi dori, Chuo Ku, Niigata, Niigata 951 8510, Japan
Calcif Tissue Int 84:38-44. 2009..Further studies will thus be needed to establish appropriate methods for assessing cancellous bone connectivity in clinical practice... - A novel type of encephalopathy associated with mushroom Sugihiratake ingestion in patients with chronic kidney diseasesFumitake Gejyo
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 68:188-92. 2005..While the exact etiology of this encephalopathy remained mysterious, we aimed to describe its clinical features... - Patient with diffuse mesangial and endocapillary proliferative glomerulonephritis with hypocomplementemia and elevated anti-streptolysin O treated with prednisolone, angiotensin-converting enzyme inhibitor, and angiotensin II receptor antagonistSatoshi Ito
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Niigata 951 8510, Japan
Clin Exp Nephrol 7:290-5. 2003..It is possible that this use of an angiotensin converting-enzyme inhibitor and an angiotensin II receptor antagonist was effective in reducing the proteinuria in this patient... - Current clinical and pathogenetic understanding of beta2-m amyloidosis in long-term haemodialysis patientsFumitake Gejyo
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Japan
Nephrology (Carlton) 8:S45-9. 2003..However, proof is lacking that amyloid deposits are decreased by long-term use of dialysis techniques to eliminate beta2-m. More effective treatment procedures are needed... - Intact PTH assay overestimates true 1-84 PTH levels after maxacalcitol therapy in dialysis patients with secondary hyperparathyroidismJunichiro J Kazama
FJSIM, Division of Intensive Care Medicine, Niigata University Medical Hospital, 1 754 Asahimachi dori, Niigata, Niigata 951 8510, Japan
Nephrol Dial Transplant 19:892-7. 2004..Previous studies have shown that the results of these two PTH assays in dialysis patients are closely correlated... - Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansionYohei Ikezumi
Department of Pediatrics, Niigata University Medical and Dental Hospital, Niigata 951 8510 Japan
Histopathology 58:198-210. 2011..Therefore, the aim of this study was to investigate whether M2 macrophages are present in new-onset IgAN and if they are related to pathological differences between paediatric and adult disease... - A patient with severe hypercalcemia in multiple organ dysfunction syndrome: role of elevated circulating 1alpha,25(OH)2 vitamin D levelsJunichiro James Kazama
Division of Critical and Intensive Care Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan
J Bone Miner Res 25:1455-9. 2010..Extrarenal activation of CYP27B1 seems to play a role in the development of hypercalcemia in this disease condition. Clinicians need to be aware that severe hypercalcemia may occur in MODS patients... - Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patientsJunichiro J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 67:1120-5. 2005..Fibroblast growth factor-23 (FGF-23) is a newly found circulating phosphaturic factor. Its circulating level is elevated in uremia... - Cancellous bone volume is an indicator for trabecular bone connectivity in dialysis patientsJunichiro James Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Chuo Ku, Niigata, Japan
Clin J Am Soc Nephrol 5:292-8. 2010..The system measures cancellous bone volume (BV/TV) as a third major evaluation axis; however, the physiologic significance of BV/TV remains unclear... - Mizoribine therapy in a patient with lupus nephritis: the association between mizoribine concentration and peritoneal dialysisTakeshi Kuroda
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1 757 Asahimachi dori, Cyuuou ku, Niigata 951 8510, Japan
Mod Rheumatol 20:296-300. 2010..Treatment with MZR was safe and useful even while undergoing CAPD. Achieving optimal MZR blood concentration was important for treatment of SLE, even though the patient was in end-stage renal failure... - Effect of ciclesonide on bronchial asthma in athletesToshiyuki Koya
Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course in Biological Functions and Medical Control, Niigata University, Graduate School of Medical and Dental Sciences, Niigata City, Niigata, Japan
J Asthma 46:1032-6. 2009.... - The risk of gallbladder stone formation is increased in patients with predialysis chronic kidney disease but not those undergoing chronic hemodialysis therapyJunichiro James Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Nephron Clin Pract 111:c167-72. 2009..It is unclear whether the prevalence of gallbladder stones (GBS) is higher in patients with chronic kidney disease (CKD)... - Direct comparison between two 1-84PTH assays in dialysis patientsJunichiro J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Nephron Clin Pract 99:c8-12. 2005..Today, two kinds of 1-84PTH assays are available in clinical practice. Few studies have directly compared the results of these assays in the same plasma... - A case report of severe visceral beta2-microglobulin-derived amyloidosis without obvious joint symptoms or radiological findings in a chronic hemodialyzed patient with systemic lupus erythematosusRyo Koda
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Nagaoka Red Cross Hospital, 1 757 Asahimachi dori, Chuo Ku, Niigata, Japan
Ther Apher Dial 13:232-7. 2009..It should be noted that prominent visceral Abeta2M amyloidosis can develop without any osteoarticular symptoms or radiological abnormalities in dialyzed patients undergoing prolonged glucocorticoid therapy... - Collagenofibrotic glomerulopathy: clinicopathologic overview of a rare glomerular diseaseBassam Alchi
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Am J Kidney Dis 49:499-506. 2007..A definite diagnosis can be established when typical histological findings are supported by immunohistochemistry for specific collagen types and electron microscopy with special staining methods. No specific treatment is available... - Association of the MCP-1 gene polymorphism A-2518G with carpal-tunnel syndrome in hemodialysis patientsKentaro Omori
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
Amyloid 9:175-82. 2002..In conclusion, homozygosity for G at -2518 in the MCP-1 gene might be a candidate for the genetic marker of CTS development in Japanese hemodialysis patients... - [IgA nephropathy--pathogenesis, pathophysiology, and therapy]Ichiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Nippon Rinsho 64:397-402. 2006 - Para-capillary electron-dense deposits reduce glomerular filtration in patients with primary glomerular diseasesSachiko Fukase
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-754 Asahimachi-dori, Niigata 951-8510, Japan
Clin Exp Nephrol 10:33-9. 2006..25 or less. CONCLUSIONS: PCEDD significantly affected FF levels in patients with primary glomerular diseases. FF may not be an accurate indicator of intraglomerular blood pressure in patients with overt PCEDD... - Two distinct FSGS lesions caused by distinct etiology confirmed in a single patient in pre- and post-transplantationYumi Ito
Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Transplant 24:54-9. 2010..8 g/d within two wk. We considered that the present case showed two distinct types of FSGS lesions--one because of VUR and the other because of cyclosporine arteriolopathy--in each native kidney and transplanted kidney... - Serum cystatin C measured by a sol particle homogeneous immunoassay can accurately detect early impairment of renal functionHiroe Sato
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Exp Nephrol 12:270-6. 2008..A sol particle homogeneous immunoassay (SPIA) is a method to measure the serum cystatin C (cysC) level as a marker of the glomerular filtration rate (GFR). Recently, formulas to convert measured cysC to GFR have been developed... - Bezafibrate suppresses rat antiglomerular basement membrane crescentic glomerulonephritisDaisuke Saga
Division of Clinical Nephrology and Rheumatology, Department of Laboratory Medicine Niigata University Graduate School of Medical and Dental Sciences, Asahimachi-dori, Niigata, Japan
Kidney Int 67:1821-9. 2005..CONCLUSION: BZF markedly suppresses the activity of rat anti-GBM crescentic glomerulonephritis. Fibrates might serve as a therapeutic option for crescentic glomerulonephritis... - Short-term use of continuous positive airway pressure ameliorates glomerular hyperfiltration in patients with obstructive sleep apnoea syndromeShin-ichi Kinebuchi
Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, 951-8510, Japan
Clin Sci (Lond) 107:317-22. 2004..001). OSAS patients were generally in a glomerular-hyperfiltrating condition that appeared to cause the renal findings associated with OSAS. CPAP might prevent nephropathy by ameliorating the glomerular hyperfiltration in OSAS patients... - [Psoriasis]Ichiei Narita
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Nippon Rinsho 62:617-9. 2004 - Mortality predictors after 10 years of dialysis: a prospective study of Japanese hemodialysis patientsJunya Ajiro
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi Dori, Niigata, Japan
Clin J Am Soc Nephrol 2:653-60. 2007..This work aimed to examine the predictive value for death of various clinical variables after long-term hemodialysis (HD)... - Combined radioguided parathyroidectomy and intravenous vitamin D therapy for the treatment of uraemic hyperparathyroidismYuko Oyama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata University Medical Hospital, Japan
Nephrol Dial Transplant 18:iii76-8. 2003..Further study needs to elucidate whether this treatment strategy can improve the long-term prognosis of patients with secondary hyperparathyroidism.. - Successful perioperative blood purification therapy in patients with maintenance hemodialysis therapy who underwent living donor liver transplantationJ J Kazama
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Nephrol 59:229-33. 2003..The application of careful and aggressive blood purification therapy during the perioperative period is a key to successful LDLT in dialysis patients... - Osteopontin expression in acute renal allograft rejectionBassam Alchi
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Kidney Int 67:886-96. 2005..Osteopontin (OPN) is a potent chemoattractant for mononuclear cells that is up-regulated in various inflammatory states of the kidney. The role of OPN and its expression in human renal allograft rejection are unknown... - Hypersensitivity to paraoxybenzoic Acid esters (parabens) in a dialysis patientKiyoko Sato
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Nephron 92:728-9. 2002..We concluded that the allergen in this patient was not heparin but parabens. Hypereosinophilia of unknown origin often occurs in dialysis patients. Such patients may be hypersensitive to parabens... - Renovascular hypertension: a unique cause of unilateral focal segmental glomerulosclerosisBassam Alchi
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
Hypertens Res 29:203-7. 2006..This case illustrates the heterogeneous effect of the renin-angiotensin system on either kidney in patients with renovascular hypertension due to unilateral renal artery stenosis... - Natural saline-flush is sufficient to maintain patency of immobilized-urokinase double-lumen catheter used to provide temporary blood access for hemodialysisYoshikatsu Kaneko
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Blood Purif 22:473-9. 2004..Heparin-lock is conventionally used to maintain patency of the catheter, but the necessity of heparin-lock has not been determined yet... - Decreased levels of circulating alpha2-Heremans-Schmid glycoprotein/Fetuin-A (AHSG) in patients with rheumatoid arthritisHiroe Sato
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Intern Med 46:1685-91. 2007..It is often considered as a potential mediator between chronic inflammation and cardiovascular diseases. The metabolism of AHSG in patients with rheumatoid arthritis (RA) is unknown... - Atherosclerosis is accelerated in patients with long-term well-controlled systemic lupus erythematosus (SLE)Hiroe Sato
Niigata University Graduate School of Medical and Dental Sciences, Division of Nephrology and Rheumatology, 1 754 Asahimachi dori, Chuo Ku Niigata, Niigata 951 8510, Japan
Clin Chim Acta 385:35-42. 2007..It is uncertain whether atherosclerosis is accelerated in premenopausal and postmenopausal patients with long-term well-controlled systemic lupus erythematosus (SLE)... - Adult onset anaphylactoid purpura with severe gastrointestinal involvementKazumi Oshima
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata
Intern Med 42:436-42. 2003..Prophylactic use of fluconazole failed to prevent contraction of invasive mycosis. Finally, he suddenly suffered from diffuse cerebral hemorrhage. Postmortem examination revealed systemic invasive aspergillosis as the cause of death... - Acute renal failure as a complication of acquired hemophilia due to autoantibody to factor VIIIYasuhiro Otaki
Division of Clinical Nephrology and Rheumatology, Division of Cell Biology, Niigata University Graduate School of Medical and Dental Sciences, 1 757Asahimachi dori, Niigata, 951 8510, Japan
Clin Exp Nephrol 14:85-9. 2010..The levels of aPTT and concentrations of factor VIII and factor VIII inhibitor were monitored during the subsequent follow-ups... - Effects of IS-741, a synthetic anti-inflammatory agent, on bleomycin-induced lung injury in miceYuichi Shimaoka
Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University, 1 757 Asahimachi dori, Chuo Ku, Niigata, 951 8510, Japan
Lung 187:331-9. 2009..Treatment with IS-741 had an inhibitory effect on BLM-induced lung injury and fibrosis via the repression of MCP-1 or cysLTs in this murine experimental model... - Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathyFumihiro Akiyama
Human Genome Center, The Institute of Medical Science, University of Tokyo, Japan
J Hum Genet 47:532-8. 2002..000001, odds ratio = 1.91 [95% confidence interval 1.46-2.49]); SNPs in other LD blocks were not. Our data imply that some haplotype of the HLA- DRA locus has an important role in the development of IgAN in Japanese patients... - Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathyTakashi Takei
Human Genome Center, The Institute of Medical Science, University of Tokyo, Tokyo Women s Medical University, Tokyo, Japan
Am J Hum Genet 70:781-6. 2002..67, P=.000016, odds ratio = 1.88 [95% CI 1.41--2.51]). Our results suggest that these eight SNPs in selectin genes may be useful for screening populations susceptible to the IgAN phenotype that involves interstitial infiltration... - [Clinical nephrology]Yoshikatsu Kaneko
Nippon Jinzo Gakkai Shi 49:19-24. 2007 - Prevalence of chronic kidney disease (CKD) in the Japanese general population predicted by the MDRD equation modified by a Japanese coefficientEnyu Imai
Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
Clin Exp Nephrol 11:156-63. 2007..However, to date, a nationwide epidemiological study has not been conducted yet to survey the CKD population... - Renal function at the time of renal biopsy as a predictor of prognosis in patients with primary AL-type amyloidosisYutaka Osawa
Shinrakuen Hospital, 1 27 Nishi Ariake, Niigata 950 2087, Japan
Clin Exp Nephrol 8:127-33. 2004.... - [Encephalopathy of unknown etiology with suspected involvement of Pleurocybella porrigens (Pers.:Fr.) Sing. 2. Pleurocybella porrigens-encephalopathy clustering among patients with kidney failure]Fumitake Gejo
Nippon Naika Gakkai Zasshi 95:1310-5. 2006 - Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patientsWataru Obara
Human Genome Center, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
J Hum Genet 48:293-9. 2003..Our results suggest that a gene associated with susceptibility to IgAN lies within or close to the PIGR gene locus on chromosome 1q in the Japanese population... - Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathyShigeru Ohtsubo
Human Genome Center, The Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, Tokyo, 108 8639, Japan
J Hum Genet 50:30-5. 2005..048), the amino acid change might influence a class switch to increase serum IgA levels, resulting in a higher risk of IgA nephropathy... - Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney diseaseEnyu Imai
Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
Clin Exp Nephrol 11:41-50. 2007..In the present study, the equations originally developed for a Caucasian population were tested in Japanese CKD patients, and modified with the Japanese coefficient determined by the data... - [Medical networking to prevent kidney failure and life-time education: discussion]Kenjiro Kimura
Nippon Naika Gakkai Zasshi 93:965-88. 2004 - Identification of genes regulating colorectal carcinogenesis by using the algorithm for diagnosing malignant state methodYasushi Ichikawa
Second Department of Surgery, School of Medicine, Yokohama City University, Yokohama, Japan
Biochem Biophys Res Commun 296:497-506. 2002..Included in the 135 genes were tumor suppressor and growth factor-related genes and were consistent with the literature. ADMS is a reliable means for identifying genes useful for the diagnosis of cancer... - Relationship between tonsils and IgA nephropathy as well as indications of tonsillectomyYuansheng Xie
Kidney Center of PLA, Department of Nephrology, Chinese General Hospital of PLA, Beijing, China
Kidney Int 65:1135-44. 2004..However, tonsillectomy may not be enough and may not change the prognosis in IgAN patients with marked renal damage...