Research Topics
| H HatanoSummaryAffiliation: Niigata Cancer Center Hospital Country: Japan Publications
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Detail Information
Publications
Clinicopathological features of lipomas with gene fusions involving HMGA2Hiroshi Hatano
Department of Orthopaedic Surgery, Niigata Cancer Center Hospital, Niigata, Japan
Anticancer Res 28:535-8. 2008..The purpose of this study was to examine the clinical significance of the expression of fusion genes in lipomas...
A ceramic prosthesis for the treatment of tumours of the distal radiusH Hatano
Department of Orthopaedic Surgery, Niigata Cancer Center Hospital, Niigata, Japan
J Bone Joint Surg Br 88:1656-8. 2006..This method of treatment results in little pain, a moderate range of movement and satisfactory function...
Focal lymphoid hyperplasia in a lipoma, mimicking liposarcomaHiroshi Hatano
Department of Orthopedic Surgery, Niigata Cancer Center Hospital, 2 15 3 Kawagishi cho, 951 8566 Niigata City, Japan
Skeletal Radiol 35:613-8. 2006..The imaging features of this lesion as well as pathological findings of this unusual tumor are discussed...
Extracorporeal irradiated autogenous osteochondral graft: a histological studyH Hatano
Department of Orthopaedic Surgery, Niigata Cancer Center Hospital, 2 15 3, Kawagishi cho, Niigata City 951 8510, Japan
J Bone Joint Surg Br 87:1006-11. 2005..The survival of chondrocytes was confirmed with S-100 protein staining. Three specimens from the subchondral region and a tendon displayed features of regeneration. Callus was seen at the junction between host and irradiated bone...
Extraskeletal osteosarcoma of the jawHiroshi Hatano
Department of Orthopedic Surgery, Niigata Cancer Center, 2 15 3, Kawagishi cho, 951 8566 Niigata City, Japan
Skeletal Radiol 34:171-5. 2005..The differential diagnosis of this lesion as well as the imaging and pathological features of extraskeletal osteosarcoma are discussed...
Well-differentiated liposarcoma associated with benign lipomaHiroshi Hatano
Department of Orthopedic Surgery, Niigata Cancer Center Hospital, Niigata, Japan
Anticancer Res 24:1039-44. 2004..Comparison of the expression profile in these malignant and benign tumors, which had arisen in identical genetic backgrounds, confirmed the involvement of these proteins, especially cdk4, in the tumorigenesis process of WDL...
Origin of bone-forming cells in human osteosarcomas transplanted into nude mice--which cells produce bone, human or mouse?H Hatano
Department of Orthopedic Surgery, Niigata University School of Medicine, Japan
J Pathol 185:204-11. 1998..The present study showed that the HuO9 tumour produces chimeric bone formation. This is the first report to demonstrate the relationships between tumour cells and non-tumour cells in bone formation, using genetic markers...
Origin of histiocyte-like cells and multinucleated giant cells in malignant fibrous histiocytoma: neoplastic or reactive?H Hatano
Department of Orthopedic Surgery, Niigata University School of Medicine, Niigata City, Japan
Pathol Int 49:14-22. 1999..Histiocyte-like cells in MFH should be considered as a reactive monocyte/macrophage lineage rather than as an element of neoplasm...
Elevation of serum alkaline phosphatase in clear cell chondrosarcoma of boneA Ogose
Department of Orthopedic Surgery, Niigata University School of Medicine, Asahimachi 1-751, Niigata 951-8510, Japan
Anticancer Res 21:649-55. 2001..Enzyme histochemical and molecular analyses demonstrated that the tumor produced ALP. CONCLUSION: Clear cell chondrosarcoma produces ALP, which can be used as a tumor marker in diagnosis and follow-up...
Expression of metalloproteinase-13 (Collagenase-3) is induced during fracture healing in miceH Yamagiwa
Department of Orthopedic Surgery, Niigata University School of Medicine, Japan
Bone 25:197-203. 1999..In conclusion, MMP-13 plays an important role in the healing process of fractured bone in mice...
Recurrent malignant variant of phosphaturic mesenchymal tumor with oncogenic osteomalaciaA Ogose
Department of Orthopedic Surgery, Niigata University School of Medicine, Asahimachi 1, Niigata 951-8510, Japan
Skeletal Radiol 30:99-103. 2001..This case illustrates the potential lethality of incompletely removed phosphaturic mesenchymal tumors...
A PCR-ELISA assay for the detection of disseminated osteosarcoma cells in a mouse metastatic modelH Hatano
Department of Orthopaedic Surgery, Niigata University School of Medicine, 757-1 Asahimachi-Dori, Niigata, Niigata 951-8510, Japan
J Orthop Sci 6:269-75. 2001..The PCR-ELISA using Osf2 mRNA is a potential method to detect circulating osteosarcoma cells in peripheral blood...
Treatment of myxoid liposarcoma by marginal or intralesional resection combined with radiotherapyH Hatano
Department of Orthopedic Surgery, Niigata University School of Medicine, Niigata City, 950 8510, Japan
Anticancer Res 23:3045-9. 2003..1 months. The development of severe radiation-related complications was not detected. This medium follow-up study suggested that this method can achieve a high rate of local control...
In vivo bone-forming capacity of human bone marrow-derived stromal cells is stimulated by recombinant human bone morphogenetic protein-2H Yamagiwa
Department of Orthopedic Surgery, Niigata University School of Medicine, Japan
J Bone Miner Metab 19:20-8. 2001..The results of the present study demonstrate that culture-expanded HMSCs preserve the osteoblastic phenotype, and the in vivo bone-forming capacity can be promoted by rhBMP-2...
High-level expression of the coxsackievirus and adenovirus receptor messenger RNA in osteosarcoma, Ewing's sarcoma, and benign neurogenic tumors among musculoskeletal tumorsWenguang Gu
Divisions of Orthopedic Surgery and Cell Biology and Molecular Pharmacology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Clin Cancer Res 10:3831-8. 2004..CAR has been shown to function as the primary receptor for adenoviruses and to play a critical role in adenovirus entry into host cells. It is important for clinical gene therapy to determine the expression level of CAR in tumor tissues...
Histological examination of beta-tricalcium phosphate graft in human femurAkira Ogose
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Science, Niigata University, Niigata, Japan
J Biomed Mater Res 63:601-4. 2002..There was a considerable number of osteoclast-like giant cells surrounding the beta-TCP. This case illustrated that highly purified beta-TCP had prominent osteoconductive activity and biodegradable nature in human bone...
Clinical and imaging features of distended scapulothoracic bursitis: spontaneously regressed pseudotumoral lesionTakeshi Higuchi
Department of Radiology, Niigata City General Hospital, Niigata, Japan
J Comput Assist Tomogr 28:223-8. 2004..To describe clinical and imaging findings of distended scapulothoracic bursitis without scapular snapping, which is often confused with a soft tissue tumor...
Presacral multiple cellular schwannomasAkira Ogose
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Course for Biological Functions and Medical Control, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Spine (Phila Pa 1976) 28:E426-9. 2003..Case report. The authors documented a patient presenting with multiple cellular schwannomas along the sciatic nerve. The patient had no stigmas of neurofibromatosis. Thirteen tumors were resected via both anterior and posterior approaches...
Alveolar soft part sarcoma in Japan: multi-institutional study of 57 patients from the Japanese Musculoskeletal Oncology GroupAkira Ogose
Division of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
Oncology 65:7-13. 2003..The efficacy of chemotherapy for soft tissue sarcoma, including high-dose ifosfamide and cisplatin, has not been established yet. Some reports suggest ASPS may occur primarily in bone...
Expression of the coxsackievirus and adenovirus receptor in musculoskeletal tumors and mesenchymal tissues: efficacy of adenoviral gene therapy for osteosarcomaHiroyuki Kawashima
Division of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1 Asahimachi dori, Niigata 951 8510
Cancer Sci 94:70-5. 2003..Most osteosarcomas appeared to express high levels of CAR, and thus adenovirus-mediated p53 gene therapy is likely to be suitable for the treatment of such tumors...
Diagnosis of peripheral nerve sheath tumors around the pelvisAkira Ogose
Division of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951 8510, Japan
Jpn J Clin Oncol 34:405-13. 2004..To distinguish between benign and malignant peripheral nerve sheath tumors around the pelvis...
Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytesHiroshi Hatano
Department of Orthopedic Research, Mayo Clinic and Foundation, MSB 3-69, 200 First Street SW, Rochester, MN 55905, USA
J Orthop Sci 8:842-8. 2003..We suggest that statins have implications for fracture and cartilage repair...
Effect of dexamethasone on growth inhibition and chondrogenic maturation of human chondrosarcomaHiroyuki Kawashima
Division of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1 Asahimachi-dori, Niigata 951-8510, Japan
J Orthop Sci 8:341-5. 2003..These results suggest that dexamethasone caused growth inhibition and induced chondrogenic maturation of human chondrosarcoma cells...
Pathological fracture of the femur ten years after successful radiation therapy for metastatic breast cancerHiroshi Hatano
Department of Orthopedic Surgery, Niigata Cancer Center Hospital, 2-15-3, Kawagishi-cho, Niigata City, 951-8566, Japan
Breast Cancer 11:313-7. 2004..Late complications of radiation therapy should be considered with care, even when metastatic lesions demonstrate complete response to treatment...
Cis-acting intronic elements that regulate cartilage-specific alternative splicing of the type II collagen (Col2) pre-mRNA lie at or near splice site junction sequences flanking exon 2 of the geneTakayuki Nishiyama
Department of Orthopedic Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
J Bone Miner Res 18:1716-22. 2003....
Plexiform schwannoma of the forearmKeiichi Katsumi
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachi 1-751, 951-8510 Niigata, Japan
Skeletal Radiol 32:719-23. 2003..Pre-operative diagnosis of the rare plexiform schwannoma may be possible with careful imaging examination for the target sign...
Expression of the cartilage derived anti-angiogenic factor chondromodulin-I decreases in the early stage of experimental osteoarthritisTadashi Hayami
Department of Orthopedic Surgery, Niigata University School of Medicine (NUSM, Niigata, Japan
J Rheumatol 30:2207-17. 2003..These findings suggest the loss of ChM-I from articular cartilage might be responsible in part for promoting blood vessel invasion into the cartilage during progression of OA...
