Genomes and Genes
Affiliation: Nihon Schering K.K
- Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cellsHideyuki Migita
Cardiovascular Research, Drug Discovery Institute, Nihon Schering K K, 1900 1, Togo Mobara, Chiba 297 0017, Japan
FEBS Lett 561:69-74. 2004..Furthermore, the expression of Rev-erbalpha was upregulated by RORalpha1 but that upregulation was attenuated by Rev-erbalpha itself in A7r5 VSMCs. These results suggest a regulatory link between Rev-erbalpha and the NF-kappaB pathway...
- RORalpha1 and RORalpha4 suppress TNF-alpha-induced VCAM-1 and ICAM-1 expression in human endothelial cellsHideyuki Migita
Cardiovascular Research, Drug Discovery Institute, Nihon Schering KK, 1900 1, Togo Mobara, Chiba 297 0017, Japan
FEBS Lett 557:269-74. 2004..These results suggest that RORalpha1 and RORalpha4 regulate the inflammatory responses via inhibition of the nuclear factor-kappaB signaling pathway in endothelial cells...
- 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis facHideyuki Migita
Department of Pharmacology, Berlex Biosciences, Richmond, CA 94806, USA
Arterioscler Thromb Vasc Biol 25:710-6. 2005....